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Items: 13

1.

Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA, Johnstone RW.

Cancer Res. 2003 Aug 1;63(15):4460-71.

2.

P-glycoprotein inhibits caspase-8 activation but not formation of the death inducing signal complex (disc) following Fas ligation.

Ruefli AA, Tainton KM, Darcy PK, Smyth MJ, Johnstone RW.

Cell Death Differ. 2002 Nov;9(11):1266-72.

3.

Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells.

Ruefli AA, Bernhard D, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.

Int J Cancer. 2002 May 10;99(2):292-8.

4.

Apoptosis: a link between cancer genetics and chemotherapy.

Johnstone RW, Ruefli AA, Lowe SW.

Cell. 2002 Jan 25;108(2):153-64. Review.

5.

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.

Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.

Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10833-8. Epub 2001 Sep 4.

6.

P-glycoprotein does not protect cells against cytolysis induced by pore-forming proteins.

Johnstone RW, Tainton KM, Ruefli AA, Froelich CJ, Cerruti L, Jane SM, Smyth MJ.

J Biol Chem. 2001 May 18;276(20):16667-73. Epub 2001 Feb 20.

7.

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

Sutton VR, Davis JE, Cancilla M, Johnstone RW, Ruefli AA, Sedelies K, Browne KA, Trapani JA.

J Exp Med. 2000 Nov 20;192(10):1403-14.

8.

Equivalent death of P-glycoprotein expressing and nonexpressing cells induced by the protein kinase C inhibitor staurosporine.

Tainton KM, Ruefli AA, Smyth MJ, Johnstone RW.

Biochem Biophys Res Commun. 2000 Sep 16;276(1):231-7.

PMID:
11006111
9.

A role for P-glycoprotein in regulating cell death.

Johnstone RW, Ruefli AA, Tainton KM, Smyth MJ.

Leuk Lymphoma. 2000 Jun;38(1-2):1-11. Review.

PMID:
10811443
10.
11.

Multiple physiological functions for multidrug transporter P-glycoprotein?

Johnstone RW, Ruefli AA, Smyth MJ.

Trends Biochem Sci. 2000 Jan;25(1):1-6. Review.

PMID:
10637601
12.

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.

Buxbaum JD, Ruefli AA, Parker CA, Cypess AM, Greengard P.

Proc Natl Acad Sci U S A. 1994 May 10;91(10):4489-93.

13.

Expression of APP in brains of transgenic mice containing the entire human APP gene.

Buxbaum JD, Christensen JL, Ruefli AA, Greengard P, Loring JF.

Biochem Biophys Res Commun. 1993 Dec 15;197(2):639-45.

PMID:
8267600

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