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Items: 1 to 50 of 52

1.

Caseload management and outcome of patients with aortic stenosis in primary/secondary versus tertiary care settings-design of the IMPULSE enhanced registry.

Rudolph TK, Messika-Zeitoun D, Frey N, Lutz M, Krapf L, Passefort S, Fryearson J, Simpson H, Mortensen K, Rehse S, Tiroke A, Dodos F, Mies F, Pohlmann C, Kurucova J, Thoenes M, Bramlage P, Steeds RP.

Open Heart. 2019 Jul 21;6(2):e001019. doi: 10.1136/openhrt-2019-001019. eCollection 2019.

2.

Balloon-expandable transcatheter aortic valve implantation with or without pre-dilation - results of a meta-analysis of 3 multicenter registries.

Ashauer JO, Bonaros N, Kofler M, Schymik G, Butter C, Romano M, Bapat V, Strauch J, Schröfel H, Busjahn A, Deutsch C, Bramlage P, Kurucova J, Thoenes M, Baldus S, Rudolph TK.

BMC Cardiovasc Disord. 2019 Jul 19;19(1):172. doi: 10.1186/s12872-019-1151-y.

3.

Symptoms, disease severity and treatment of adults with a new diagnosis of severe aortic stenosis.

Frey N, Steeds RP, Rudolph TK, Thambyrajah J, Serra A, Schulz E, Maly J, Aiello M, Lloyd G, Bortone AS, Hauptmann KE, Clerici A, Delle Karth G, Rieber J, Indorfi C, Mancone M, Belle L, Lauten A, Arnold M, Bouma BJ, Lutz M, Pohlmann C, Kurucova J, Thoenes M, Bramlage P, Messika-Zeitoun D; IMPULSE registry group.

Heart. 2019 Jul 13. pii: heartjnl-2019-314940. doi: 10.1136/heartjnl-2019-314940. [Epub ahead of print]

PMID:
31302639
4.

Degree of valve calcification in patients undergoing transfemoral transcatheter aortic valve implantation with and without balloon aortic valvuloplasty: Findings from the multicenter EASE-IT TF registry.

Butter C, Okamoto M, Schymik G, Jacobshagen C, Rothe J, Treede H, Kerber S, Frank D, Bramlage P, Sykorova L, Thoenes M, Rudolph TK.

Catheter Cardiovasc Interv. 2019 Mar 13. doi: 10.1002/ccd.28164. [Epub ahead of print]

PMID:
30866154
5.

Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.

Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi GA, Aytekin M, Dweik RA, Hennigs JK, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph TK, Hazen SL, Klose H, Schermuly RT, Rudolph V, Baldus S.

JCI Insight. 2018 Jun 7;3(11). pii: 97530. doi: 10.1172/jci.insight.97530. eCollection 2018 Jun 7.

6.

Predictors of paravalvular regurgitation and permanent pacemaker implantation after TAVR with a next-generation self-expanding device.

Mauri V, Deuschl F, Frohn T, Schofer N, Linder M, Kuhn E, Schaefer A, Rudolph V, Madershahian N, Conradi L, Rudolph TK, Schäfer U.

Clin Res Cardiol. 2018 Aug;107(8):688-697. doi: 10.1007/s00392-018-1235-1. Epub 2018 Apr 17.

PMID:
29667013
7.

Short-Term Outcome and Hemodynamic Performance of Next-Generation Self-Expanding Versus Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annulus: A Multicenter Propensity-Matched Comparison.

Mauri V, Kim WK, Abumayyaleh M, Walther T, Moellmann H, Schaefer U, Conradi L, Hengstenberg C, Hilker M, Wahlers T, Baldus S, Rudolph V, Madershahian N, Rudolph TK.

Circ Cardiovasc Interv. 2017 Oct;10(10). pii: e005013. doi: 10.1161/CIRCINTERVENTIONS.117.005013.

PMID:
28951395
8.

Prasugrel as opposed to clopidogrel improves endothelial nitric oxide bioavailability and reduces platelet-leukocyte interaction in patients with unstable angina pectoris: A randomized controlled trial.

Rudolph TK, Fuchs A, Klinke A, Schlichting A, Friedrichs K, Hellmich M, Mollenhauer M, Schwedhelm E, Baldus S, Rudolph V.

Int J Cardiol. 2017 Dec 1;248:7-13. doi: 10.1016/j.ijcard.2017.06.099. Epub 2017 Jul 1.

PMID:
28709700
9.

Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling.

Mollenhauer M, Friedrichs K, Lange M, Gesenberg J, Remane L, Kerkenpaß C, Krause J, Schneider J, Ravekes T, Maass M, Halbach M, Peinkofer G, Saric T, Mehrkens D, Adam M, Deuschl FG, Lau D, Geertz B, Manchanda K, Eschenhagen T, Kubala L, Rudolph TK, Wu Y, Tang WHW, Hazen SL, Baldus S, Klinke A, Rudolph V.

Circ Res. 2017 Jun 23;121(1):56-70. doi: 10.1161/CIRCRESAHA.117.310870. Epub 2017 Apr 12.

10.

Nitro-oleic acid regulates growth factor-induced differentiation of bone marrow-derived macrophages.

Verescakova H, Ambrozova G, Kubala L, Perecko T, Koudelka A, Vasicek O, Rudolph TK, Klinke A, Woodcock SR, Freeman BA, Pekarova M.

Free Radic Biol Med. 2017 Mar;104:10-19. doi: 10.1016/j.freeradbiomed.2017.01.003. Epub 2017 Jan 4.

11.

Catheter Insertion via Extracorporeal Membrane Oxygenation Cannula during Transcatheter Aortic Valve Implantation.

Kuhn EW, Madershahian N, Rudolph TK, Scherner M, Choi YH, Wahlers T.

Thorac Cardiovasc Surg Rep. 2016 Dec;5(1):41-43. doi: 10.1055/s-0036-1572512. Epub 2016 Feb 24.

12.

Nitro-Oleic Acid Prevents Hypoxia- and Asymmetric Dimethylarginine-Induced Pulmonary Endothelial Dysfunction.

Koudelka A, Ambrozova G, Klinke A, Fidlerova T, Martiskova H, Kuchta R, Rudolph TK, Kadlec J, Kuchtova Z, Woodcock SR, Freeman BA, Kubala L, Pekarova M.

Cardiovasc Drugs Ther. 2016 Dec;30(6):579-586.

13.

Predictors of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement With the SAPIEN 3.

Mauri V, Reimann A, Stern D, Scherner M, Kuhn E, Rudolph V, Rosenkranz S, Eghbalzadeh K, Friedrichs K, Wahlers T, Baldus S, Madershahian N, Rudolph TK.

JACC Cardiovasc Interv. 2016 Nov 14;9(21):2200-2209. doi: 10.1016/j.jcin.2016.08.034.

14.

Nitro-oleic acid inhibits vascular endothelial inflammatory responses and the endothelial-mesenchymal transition.

Ambrozova G, Fidlerova T, Verescakova H, Koudelka A, Rudolph TK, Woodcock SR, Freeman BA, Kubala L, Pekarova M.

Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2428-2437. doi: 10.1016/j.bbagen.2016.07.010. Epub 2016 Jul 16.

15.

Successful treatment of an iatrogenic membranous ventricular septal defect (IVSD) following Edwards SAPIEN 3 implantation by a valve-in-valve procedure.

Rudolph TK, Scherner M, Kuhn E, Rudolph V, Mauri V, Rosenkranz S, Wahlers T, Baldus S, Mader N.

EuroIntervention. 2016 Apr 20;11(13):1562. doi: 10.4244/EIJV11I13A300. No abstract available.

16.

Nitro-oleic acid modulates classical and regulatory activation of macrophages and their involvement in pro-fibrotic responses.

Ambrozova G, Martiskova H, Koudelka A, Ravekes T, Rudolph TK, Klinke A, Rudolph V, Freeman BA, Woodcock SR, Kubala L, Pekarova M.

Free Radic Biol Med. 2016 Jan;90:252-260. doi: 10.1016/j.freeradbiomed.2015.11.026. Epub 2015 Nov 24.

17.

Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation.

Rudolph TK, Ravekes T, Klinke A, Friedrichs K, Mollenhauer M, Pekarova M, Ambrozova G, Martiskova H, Kaur JJ, Matthes B, Schwoerer A, Woodcock SR, Kubala L, Freeman BA, Baldus S, Rudolph V.

Cardiovasc Res. 2016 Jan 1;109(1):174-84. doi: 10.1093/cvr/cvv254. Epub 2015 Nov 23.

18.

Focus on the surgical approach to transcatheter aortic valve implantation: Complications, outcome, and preoperative risk adjustment.

Scherner M, Madershahian N, Ney S, Kuhr K, Rosenkranz S, Rudolph TK, Kuhn E, Slottosch I, Deppe A, Choi YH, Baldus S, Wahlers T.

J Thorac Cardiovasc Surg. 2015 Oct;150(4):841-9. doi: 10.1016/j.jtcvs.2015.06.030. Epub 2015 Jun 26.

19.

Levosimendan displays anti-inflammatory effects and decreases MPO bioavailability in patients with severe heart failure.

Adam M, Meyer S, Knors H, Klinke A, Radunski UK, Rudolph TK, Rudolph V, Spin JM, Tsao PS, Costard-Jäckle A, Baldus S.

Sci Rep. 2015 Apr 13;5:9704. doi: 10.1038/srep09704.

20.

Ferric carboxymaltose improves exercise capacity and quality of life in patients with pulmonary arterial hypertension and iron deficiency: a pilot study.

Viethen T, Gerhardt F, Dumitrescu D, Knoop-Busch S, ten Freyhaus H, Rudolph TK, Baldus S, Rosenkranz S.

Int J Cardiol. 2014 Aug 1;175(2):233-9. doi: 10.1016/j.ijcard.2014.04.233. Epub 2014 Apr 27.

PMID:
24880481
21.

Induction of atrial fibrillation by neutrophils critically depends on CD11b/CD18 integrins.

Friedrichs K, Adam M, Remane L, Mollenhauer M, Rudolph V, Rudolph TK, Andrié RP, Stöckigt F, Schrickel JW, Ravekes T, Deuschl F, Nickenig G, Willems S, Baldus S, Klinke A.

PLoS One. 2014 Feb 18;9(2):e89307. doi: 10.1371/journal.pone.0089307. eCollection 2014.

22.

Protective effects of 10-nitro-oleic acid in a hypoxia-induced murine model of pulmonary hypertension.

Klinke A, Möller A, Pekarova M, Ravekes T, Friedrichs K, Berlin M, Scheu KM, Kubala L, Kolarova H, Ambrozova G, Schermuly RT, Woodcock SR, Freeman BA, Rosenkranz S, Baldus S, Rudolph V, Rudolph TK.

Am J Respir Cell Mol Biol. 2014 Jul;51(1):155-62. doi: 10.1165/rcmb.2013-0063OC.

23.

Liberation of vessel-adherent myeloperoxidase reflects plaque burden in patients with stable coronary artery disease.

Rudolph TK, Schaper N, Klinke A, Demir C, Goldmann B, Lau D, Köster R, Hellmich M, Meinertz T, Baldus S, Rudolph V.

Atherosclerosis. 2013 Dec;231(2):354-8. doi: 10.1016/j.atherosclerosis.2013.09.016. Epub 2013 Sep 30.

24.

JenaValve--transfemoral technology.

Rudolph TK, Baldus S.

EuroIntervention. 2013 Sep 10;9 Suppl:S101-2. doi: 10.4244/EIJV9SSA20. No abstract available.

PMID:
24025944
25.

Asymmetric dimethylarginine regulates the lipopolysaccharide-induced nitric oxide production in macrophages by suppressing the activation of NF-kappaB and iNOS expression.

Pekarova M, Kubala L, Martiskova H, Bino L, Twarogova M, Klinke A, Rudolph TK, Kuchtova Z, Kolarova H, Ambrozova G, Kuchta R, Kadlec J, Lojek A.

Eur J Pharmacol. 2013 Aug 5;713(1-3):68-77. doi: 10.1016/j.ejphar.2013.05.001. Epub 2013 May 9.

PMID:
23665490
26.

Diagnostic and prognostic performance of myeloperoxidase plasma levels compared with sensitive troponins in patients admitted with acute onset chest pain.

Rudolph V, Keller T, Schulz A, Ojeda F, Rudolph TK, Tzikas S, Bickel C, Meinertz T, Münzel T, Blankenberg S, Baldus S.

Circ Cardiovasc Genet. 2012 Oct 1;5(5):561-8. doi: 10.1161/CIRCGENETICS.111.962290. Epub 2012 Aug 24.

PMID:
22923422
27.

Myeloperoxidase deficiency preserves vasomotor function in humans.

Rudolph TK, Wipper S, Reiter B, Rudolph V, Coym A, Detter C, Lau D, Klinke A, Friedrichs K, Rau T, Pekarova M, Russ D, Knöll K, Kolk M, Schroeder B, Wegscheider K, Andresen H, Schwedhelm E, Boeger R, Ehmke H, Baldus S.

Eur Heart J. 2012 Jul;33(13):1625-34. doi: 10.1093/eurheartj/ehr193. Epub 2011 Jun 30.

28.

Nitroalkylation--a redox sensitive signaling pathway.

Geisler AC, Rudolph TK.

Biochim Biophys Acta. 2012 Jun;1820(6):777-84. doi: 10.1016/j.bbagen.2011.06.014. Epub 2011 Jun 24. Review.

PMID:
21723375
29.

Electrophilic fatty acids regulate matrix metalloproteinase activity and expression.

Bonacci G, Schopfer FJ, Batthyany CI, Rudolph TK, Rudolph V, Khoo NK, Kelley EE, Freeman BA.

J Biol Chem. 2011 May 6;286(18):16074-81. doi: 10.1074/jbc.M111.225029. Epub 2011 Mar 15.

30.

Myeloperoxidase attracts neutrophils by physical forces.

Klinke A, Nussbaum C, Kubala L, Friedrichs K, Rudolph TK, Rudolph V, Paust HJ, Schröder C, Benten D, Lau D, Szocs K, Furtmüller PG, Heeringa P, Sydow K, Duchstein HJ, Ehmke H, Schumacher U, Meinertz T, Sperandio M, Baldus S.

Blood. 2011 Jan 27;117(4):1350-8. doi: 10.1182/blood-2010-05-284513. Epub 2010 Oct 27.

31.

Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction.

Rudolph V, Goldmann BU, Bös C, Rudolph TK, Klinke A, Friedrichs K, Lau D, Wegscheider K, Haddad M, Meinertz T, Baldus S.

Int J Cardiol. 2011 Dec 15;153(3):267-71. doi: 10.1016/j.ijcard.2010.08.015. Epub 2010 Sep 16.

PMID:
20846733
32.

Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids.

Groeger AL, Cipollina C, Cole MP, Woodcock SR, Bonacci G, Rudolph TK, Rudolph V, Freeman BA, Schopfer FJ.

Nat Chem Biol. 2010 Jun;6(6):433-41. doi: 10.1038/nchembio.367. Epub 2010 May 2.

33.

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.

Rudolph V, Andrié RP, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer AP, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner EC, Szoecs K, Schrickel JW, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann WH, Meinertz T, Böger RH, Reichenspurner H, Freeman BA, Eschenhagen T, Ehmke H, Hazen SL, Willems S, Baldus S.

Nat Med. 2010 Apr;16(4):470-4. doi: 10.1038/nm.2124. Epub 2010 Mar 21.

34.

Nitro-fatty acids reduce atherosclerosis in apolipoprotein E-deficient mice.

Rudolph TK, Rudolph V, Edreira MM, Cole MP, Bonacci G, Schopfer FJ, Woodcock SR, Franek A, Pekarova M, Khoo NK, Hasty AH, Baldus S, Freeman BA.

Arterioscler Thromb Vasc Biol. 2010 May;30(5):938-45. doi: 10.1161/ATVBAHA.109.201582. Epub 2010 Feb 18.

35.

Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions.

Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, Xu HE, Batthyany CI, Chen YE, Hallis TM, Freeman BA.

J Biol Chem. 2010 Apr 16;285(16):12321-33. doi: 10.1074/jbc.M109.091512. Epub 2010 Jan 22.

36.

Transduction of redox signaling by electrophile-protein reactions.

Rudolph TK, Freeman BA.

Sci Signal. 2009 Sep 29;2(90):re7. doi: 10.1126/scisignal.290re7. Review.

37.

Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury.

Cole MP, Rudolph TK, Khoo NK, Motanya UN, Golin-Bisello F, Wertz JW, Schopfer FJ, Rudolph V, Woodcock SR, Bolisetty S, Ali MS, Zhang J, Chen YE, Agarwal A, Freeman BA, Bauer PM.

Circ Res. 2009 Nov 6;105(10):965-72. doi: 10.1161/CIRCRESAHA.109.199075. Epub 2009 Sep 24.

38.

A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function.

Rudolph V, Rudolph TK, Kubala L, Clauberg N, Maas R, Pekarova M, Klinke A, Lau D, Szöcs K, Meinertz T, Böger RH, Baldus S.

Free Radic Biol Med. 2009 Dec 1;47(11):1584-90. doi: 10.1016/j.freeradbiomed.2009.09.001. Epub 2009 Sep 6.

PMID:
19735726
39.

Endogenous generation and protective effects of nitro-fatty acids in a murine model of focal cardiac ischaemia and reperfusion.

Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Woodcock SR, Cole MP, Baker PR, Ramani R, Freeman BA.

Cardiovasc Res. 2010 Jan 1;85(1):155-66. doi: 10.1093/cvr/cvp275.

40.

Neutrophil activation precedes myocardial injury in patients with acute myocardial infarction.

Goldmann BU, Rudolph V, Rudolph TK, Holle AK, Hillebrandt M, Meinertz T, Baldus S.

Free Radic Biol Med. 2009 Jul 1;47(1):79-83. doi: 10.1016/j.freeradbiomed.2009.04.004. Epub 2009 Apr 9.

PMID:
19362143
41.

Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives.

Schopfer FJ, Batthyany C, Baker PR, Bonacci G, Cole MP, Rudolph V, Groeger AL, Rudolph TK, Nadtochiy S, Brookes PS, Freeman BA.

Free Radic Biol Med. 2009 May 1;46(9):1250-9. doi: 10.1016/j.freeradbiomed.2008.12.025.

42.

Liberation of vessel adherent myeloperoxidase by enoxaparin improves endothelial function.

Rudolph TK, Rudolph V, Witte A, Klinke A, Szoecs K, Lau D, Heitzer T, Meinertz T, Baldus S.

Int J Cardiol. 2010 Apr 1;140(1):42-7. doi: 10.1016/j.ijcard.2008.10.035. Epub 2008 Dec 2.

PMID:
19049846
43.

Contribution of myeloperoxidase to smoking-dependent vascular inflammation.

Rudolph TK, Rudolph V, Baldus S.

Proc Am Thorac Soc. 2008 Dec 1;5(8):820-3. doi: 10.1513/pats.200807-063TH.

PMID:
19017736
44.

Nitro-fatty acid metabolome: saturation, desaturation, beta-oxidation, and protein adduction.

Rudolph V, Schopfer FJ, Khoo NK, Rudolph TK, Cole MP, Woodcock SR, Bonacci G, Groeger AL, Golin-Bisello F, Chen CS, Baker PR, Freeman BA.

J Biol Chem. 2009 Jan 16;284(3):1461-73. doi: 10.1074/jbc.M802298200. Epub 2008 Nov 17.

45.

Copper trafficking and extracellular superoxide dismutase activity: kinky hair, kinky vessels.

Rudolph V, Rudolph TK, Freeman BA.

Hypertension. 2008 Nov;52(5):811-2. doi: 10.1161/HYPERTENSIONAHA.108.117770. Epub 2008 Sep 2. No abstract available.

46.

Bivalirudin decreases NO bioavailability by vascular immobilization of myeloperoxidase.

Rudolph V, Rudolph TK, Schopfer FJ, Bonacci G, Lau D, Szöcs K, Klinke A, Meinertz T, Freeman BA, Baldus S.

J Pharmacol Exp Ther. 2008 Nov;327(2):324-31. doi: 10.1124/jpet.108.142414. Epub 2008 Aug 13.

47.

Blood pressure regulation: role for neutrophils?

Rudolph V, Rudolph TK, Freeman BA.

Blood. 2008 May 15;111(10):4840. doi: 10.1182/blood-2008-03-142513.

48.

Activation of polymorphonuclear neutrophils in patients with impaired left ventricular function.

Rudolph V, Rudolph TK, Hennings JC, Blankenberg S, Schnabel R, Steven D, Haddad M, Knittel K, Wende S, Wenzel J, Münzel T, Heitzer T, Meinertz T, Hübner C, Baldus S.

Free Radic Biol Med. 2007 Oct 15;43(8):1189-96. Epub 2007 Jul 19.

PMID:
17854714
49.

Acute effects of various fast-food meals on vascular function and cardiovascular disease risk markers: the Hamburg Burger Trial.

Rudolph TK, Ruempler K, Schwedhelm E, Tan-Andresen J, Riederer U, Böger RH, Maas R.

Am J Clin Nutr. 2007 Aug;86(2):334-40.

PMID:
17684202
50.

Asymmetric dimethylarginine determines the improvement of endothelium-dependent vasodilation by simvastatin: Effect of combination with oral L-arginine.

Böger GI, Rudolph TK, Maas R, Schwedhelm E, Dumbadze E, Bierend A, Benndorf RA, Böger RH.

J Am Coll Cardiol. 2007 Jun 12;49(23):2274-82. Epub 2007 May 25.

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