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Items: 1 to 50 of 65

1.

Metabolism and pharmacokinetics characterization of metarrestin in multiple species.

Padilha EC, Shah P, Wang AQ, Singleton MD, Hughes EA, Li D, Rice KA, Konrath KM, Patnaik S, Marugan J, Rudloff U, Xu X.

Cancer Chemother Pharmacol. 2020 Apr;85(4):805-816. doi: 10.1007/s00280-020-04042-y. Epub 2020 Mar 17.

PMID:
32185484
2.

Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.

Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaax6337. doi: 10.1126/scitranslmed.aax6337.

PMID:
32051227
3.

LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies.

O'Neill MJ, Chan K, Jaynes JM, Knotts Z, Xu X, Abisoye-Ogunniyan A, Guerin T, Schlomer J, Li D, Cary JW, Rajasekaran K, Yates C, Kozlov S, Andresson T, Rudloff U.

J Pharm Biomed Anal. 2020 Mar 20;181:113093. doi: 10.1016/j.jpba.2020.113093. Epub 2020 Jan 2.

PMID:
31931447
4.

Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.

Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF 3rd, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ.

Cancer Discov. 2020 Jan;10(1):104-123. doi: 10.1158/2159-8290.CD-19-1006. Epub 2019 Oct 24.

PMID:
31649109
5.

Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.

Bian Y, Teper Y, Mathews Griner LA, Aiken TJ, Shukla V, Guha R, Shinn P, Xin HW, Pflicke H, Powers AS, Li D, Jiang JK, Patel P, Rogers SA, Aubé J, Ferrer M, Thomas CJ, Rudloff U.

Mol Cancer Ther. 2019 Nov;18(11):2097-2110. doi: 10.1158/1535-7163.MCT-18-1011. Epub 2019 Aug 8.

PMID:
31395684
6.

Associations of CDH1 germline variant location and cancer phenotype in families with hereditary diffuse gastric cancer (HDGC).

Lo W, Zhu B, Sabesan A, Wu HH, Powers A, Sorber RA, Ravichandran S, Chen I, McDuffie LA, Quadri HS, Beane JD, Calzone K, Miettinen MM, Hewitt SM, Koh C, Heller T, Wacholder S, Rudloff U.

J Med Genet. 2019 Jun;56(6):370-379. doi: 10.1136/jmedgenet-2018-105361. Epub 2019 Feb 11.

7.

Gastric adenocarcinoma and proximal polyposis of the stomach: diagnosis and clinical perspectives.

Rudloff U.

Clin Exp Gastroenterol. 2018 Dec 3;11:447-459. doi: 10.2147/CEG.S163227. eCollection 2018. Review.

8.

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.

Vilimas T, Wang AQ, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U.

Cancer Chemother Pharmacol. 2018 Dec;82(6):1067-1080. doi: 10.1007/s00280-018-3699-0. Epub 2018 Oct 10.

9.

Loss of PDPK1 abrogates resistance to gemcitabine in label-retaining pancreatic cancer cells.

Li D, Mullinax JE, Aiken T, Xin H, Wiegand G, Anderson A, Thorgeirsson S, Avital I, Rudloff U.

BMC Cancer. 2018 Jul 31;18(1):772. doi: 10.1186/s12885-018-4690-1.

10.

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.

Frankowski KJ, Wang C, Patnaik S, Schoenen FJ, Southall N, Li D, Teper Y, Sun W, Kandela I, Hu D, Dextras C, Knotts Z, Bian Y, Norton J, Titus S, Lewandowska MA, Wen Y, Farley KI, Griner LM, Sultan J, Meng Z, Zhou M, Vilimas T, Powers AS, Kozlov S, Nagashima K, Quadri HS, Fang M, Long C, Khanolkar O, Chen W, Kang J, Huang H, Chow E, Goldberg E, Feldman C, Xi R, Kim HR, Sahagian G, Baserga SJ, Mazar A, Ferrer M, Zheng W, Shilatifard A, Aubé J, Rudloff U, Marugan JJ, Huang S.

Sci Transl Med. 2018 May 16;10(441). pii: eaap8307. doi: 10.1126/scitranslmed.aap8307.

11.
12.

Adjuvant intraperitoneal chemotherapy for the treatment of colorectal cancer at risk for peritoneal carcinomatosis: a systematic review.

Feingold PL, Klemen ND, Kwong MLM, Hashimoto B, Rudloff U.

Int J Hyperthermia. 2018 Aug;34(5):501-511. doi: 10.1080/02656736.2017.1401742. Epub 2017 Dec 7.

PMID:
29214884
13.

The Changing Paradigm of Management of Liver Abscesses in Chronic Granulomatous Disease.

Straughan DM, McLoughlin KC, Mullinax JE, Marciano BE, Freeman AF, Anderson VL, Uzel G, Azoury SC, Sorber R, Quadri HS, Malech HL, DeRavin SS, Kamal N, Koh C, Zerbe CS, Kuhns DB, Gallin JI, Heller T, Holland SM, Rudloff U.

Clin Infect Dis. 2018 Apr 17;66(9):1427-1434. doi: 10.1093/cid/cix1012.

14.

Expression of the scaffold connector enhancer of kinase suppressor of Ras 1 (CNKSR1) is correlated with clinical outcome in pancreatic cancer.

Quadri HS, Aiken TJ, Allgaeuer M, Moravec R, Altekruse S, Hussain SP, Miettinen MM, Hewitt SM, Rudloff U.

BMC Cancer. 2017 Jul 21;17(1):495. doi: 10.1186/s12885-017-3481-4.

15.

Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer.

Chen I, Mathews-Greiner L, Li D, Abisoye-Ogunniyan A, Ray S, Bian Y, Shukla V, Zhang X, Guha R, Thomas C, Gryder B, Zacharia A, Beane JD, Ravichandran S, Ferrer M, Rudloff U.

J Transl Med. 2017 May 1;15(1):92. doi: 10.1186/s12967-017-1197-5.

16.

Adjuvant intraperitoneal chemotherapy for the treatment of gastric cancer at risk for peritoneal carcinomatosis: A systematic review.

Feingold PL, Kwong ML, Davis JL, Rudloff U.

J Surg Oncol. 2017 Feb;115(2):192-201. doi: 10.1002/jso.24476. Epub 2016 Nov 23. Review.

PMID:
27878811
17.

β-Catenin activation in fundic gland polyps, gastric cancer and colonic polyps in families afflicted by 'gastric adenocarcinoma and proximal polyposis of the stomach' (GAPPS).

McDuffie LA, Sabesan A, Allgäeuer M, Xin L, Koh C, Heller T, Davis JL, Raffeld M, Miettienen M, Quezado M, Rudloff U.

J Clin Pathol. 2016 Sep;69(9):826-33. doi: 10.1136/jclinpath-2016-203746. Epub 2016 Jul 12.

PMID:
27406052
18.

Liver Label Retaining Cancer Cells Are Relatively Resistant to the Reported Anti-Cancer Stem Cell Drug Metformin.

Xin HW, Ambe CM, Miller TC, Chen JQ, Wiegand GW, Anderson AJ, Ray S, Mullinax JE, Hari DM, Koizumi T, Godbout JD, Goldsmith PK, Stojadinovic A, Rudloff U, Thorgeirsson SS, Avital I.

J Cancer. 2016 Jun 6;7(9):1142-51. doi: 10.7150/jca.10047. eCollection 2016.

19.

Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.

Li J, Woods SL, Healey S, Beesley J, Chen X, Lee JS, Sivakumaran H, Wayte N, Nones K, Waterfall JJ, Pearson J, Patch AM, Senz J, Ferreira MA, Kaurah P, Mackenzie R, Heravi-Moussavi A, Hansford S, Lannagan TRM, Spurdle AB, Simpson PT, da Silva L, Lakhani SR, Clouston AD, Bettington M, Grimpen F, Busuttil RA, Di Costanzo N, Boussioutas A, Jeanjean M, Chong G, Fabre A, Olschwang S, Faulkner GJ, Bellos E, Coin L, Rioux K, Bathe OF, Wen X, Martin HC, Neklason DW, Davis SR, Walker RL, Calzone KA, Avital I, Heller T, Koh C, Pineda M, Rudloff U, Quezado M, Pichurin PN, Hulick PJ, Weissman SM, Newlin A, Rubinstein WS, Sampson JE, Hamman K, Goldgar D, Poplawski N, Phillips K, Schofield L, Armstrong J, Kiraly-Borri C, Suthers GK, Huntsman DG, Foulkes WD, Carneiro F, Lindor NM, Edwards SL, French JD, Waddell N, Meltzer PS, Worthley DL, Schrader KA, Chenevix-Trench G.

Am J Hum Genet. 2016 May 5;98(5):830-842. doi: 10.1016/j.ajhg.2016.03.001. Epub 2016 Apr 14.

20.

Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion.

Sorber R, Teper Y, Abisoye-Ogunniyan A, Waterfall JJ, Davis S, Killian JK, Pineda M, Ray S, McCord MR, Pflicke H, Burkett SS, Meltzer PS, Rudloff U.

PLoS One. 2016 Mar 10;11(3):e0149833. doi: 10.1371/journal.pone.0149833. eCollection 2016.

21.

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for gastric cancer and other less common disease histologies: is it time?

Feingold PL, Kwong ML, Sabesan A, Sorber R, Rudloff U.

J Gastrointest Oncol. 2016 Feb;7(1):87-98. doi: 10.3978/j.issn.2078-6891.2015.098. Review.

22.

Duodenal ischemia and upper GI bleeding are dose-limiting toxicities of 24-h continuous intra-arterial pancreatic perfusion of gemcitabine following vascular isolation of the pancreatic head: early results from the Regional Chemotherapy in Locally Advanced Pancreatic Cancer (RECLAP) study.

Beane JD, Griffin KF, Levy EB, Pandalai P, Wood B, Abi-Jaoudeh N, Beresnev T, Shutack Y, Webb CC, Avital I, Rudloff U.

Invest New Drugs. 2015 Feb;33(1):109-18. doi: 10.1007/s10637-014-0157-7. Epub 2014 Sep 19.

23.

Impact of maximal cytoreductive surgery plus regional heated intraperitoneal chemotherapy (HIPEC) on outcome of patients with peritoneal carcinomatosis of gastric origin: results of the GYMSSA trial.

Rudloff U, Langan RC, Mullinax JE, Beane JD, Steinberg SM, Beresnev T, Webb CC, Walker M, Toomey MA, Schrump D, Pandalai P, Stojadinovic A, Avital I.

J Surg Oncol. 2014 Sep;110(3):275-84. doi: 10.1002/jso.23633. Epub 2014 Jul 5.

24.

Efficacy of adjuvant radiation therapy in the treatment of soft tissue sarcoma of the extremity: 20-year follow-up of a randomized prospective trial.

Beane JD, Yang JC, White D, Steinberg SM, Rosenberg SA, Rudloff U.

Ann Surg Oncol. 2014 Aug;21(8):2484-9. doi: 10.1245/s10434-014-3732-4. Epub 2014 Apr 23.

25.

A novel chimeric antigen receptor against prostate stem cell antigen mediates tumor destruction in a humanized mouse model of pancreatic cancer.

Abate-Daga D, Lagisetty KH, Tran E, Zheng Z, Gattinoni L, Yu Z, Burns WR, Miermont AM, Teper Y, Rudloff U, Restifo NP, Feldman SA, Rosenberg SA, Morgan RA.

Hum Gene Ther. 2014 Dec;25(12):1003-12. doi: 10.1089/hum.2013.209.

26.

ERBB4 mutation analysis: emerging molecular target for melanoma treatment.

Lau C, Killian KJ, Samuels Y, Rudloff U.

Methods Mol Biol. 2014;1102:461-80. doi: 10.1007/978-1-62703-727-3_24.

27.

An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer.

Jia J, Parikh H, Xiao W, Hoskins JW, Pflicke H, Liu X, Collins I, Zhou W, Wang Z, Powell J, Thorgeirsson SS, Rudloff U, Petersen GM, Amundadottir LT.

BMC Med Genomics. 2013 Sep 22;6:33. doi: 10.1186/1755-8794-6-33.

28.

Wnt and the cancer niche: paracrine interactions with gastrointestinal cancer cells undergoing asymmetric cell division.

Xin HW, Ambe CM, Ray S, Kim BK, Koizumi T, Wiegand GW, Hari D, Mullinax JE, Jaiswal KR, Garfield SH, Stojadinovic A, Rudloff U, Thorgeirsson SS, Avital I.

J Cancer. 2013 Jul 2;4(6):447-57. doi: 10.7150/jca.6896. Print 2013.

29.

Surgery for Li Fraumeni syndrome: pushing the limits of surgical oncology.

Langan RC, Lagisetty KH, Atay S, Pandalai P, Stojadinovic A, Rudloff U, Avital I.

Am J Clin Oncol. 2015 Feb;38(1):98-102. doi: 10.1097/COC.0b013e3182880bc5.

30.

Label-retaining liver cancer cells are relatively resistant to sorafenib.

Xin HW, Ambe CM, Hari DM, Wiegand GW, Miller TC, Chen JQ, Anderson AJ, Ray S, Mullinax JE, Koizumi T, Langan RC, Burka D, Herrmann MA, Goldsmith PK, Stojadinovic A, Rudloff U, Thorgeirsson SS, Avital I.

Gut. 2013 Dec;62(12):1777-86. doi: 10.1136/gutjnl-2012-303261. Epub 2013 Feb 14.

31.

Autoimmune pancreatitis in the autoimmune lymphoproliferative syndrome (ALPS): a sheep in wolves' clothing?

Langan RC, Gill F, Raiji MT, Mullinax JE, Pittaluga S, Pandalai P, Davis J, Perkins K, Avital I, Rudloff U.

Pancreas. 2013 Mar;42(2):363-6. doi: 10.1097/MPA.0b013e3182648778. No abstract available.

32.

A novel nomogram for peritoneal mesothelioma predicts survival.

Schaub NP, Alimchandani M, Quezado M, Kalina P, Eberhardt JS, Hughes MS, Beresnev T, Hassan R, Bartlett DL, Libutti SK, Pingpank JF, Royal RE, Kammula US, Pandalai P, Phan GQ, Stojadinovic A, Rudloff U, Alexander HR, Avital I.

Ann Surg Oncol. 2013 Feb;20(2):555-61. doi: 10.1245/s10434-012-2651-5. Epub 2012 Dec 12.

33.

Safety of major abdominal surgical procedures in patients with hyperimmunoglobulinemia E (Job's syndrome): a changing paradigm?

Langan RC, Sherry RM, Avital I, Heller T, Henderson C, Holland SM, Freeman AF, Rudloff U.

J Gastrointest Surg. 2013 May;17(5):1009-14. doi: 10.1007/s11605-012-2077-1. Epub 2012 Nov 27.

PMID:
23188219
34.

Comparative testing of various pancreatic cancer stem cells results in a novel class of pancreatic-cancer-initiating cells.

Jaiswal KR, Xin HW, Anderson A, Wiegand G, Kim B, Miller T, Hari D, Ray S, Koizumi T, Rudloff U, Thorgeirsson SS, Avital I.

Stem Cell Res. 2012 Nov;9(3):249-60. doi: 10.1016/j.scr.2012.08.001. Epub 2012 Aug 19.

35.

A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers.

Langan RC, Mullinax JE, Ray S, Raiji MT, Schaub N, Xin HW, Koizumi T, Steinberg SM, Anderson A, Wiegand G, Butcher D, Anver M, Bilchik AJ, Stojadinovic A, Rudloff U, Avital I.

J Cancer. 2012;3:231-40. doi: 10.7150/jca.4542. Epub 2012 Jun 1.

36.

Establishment of human ultra-low passage colorectal cancer cell lines using spheroids from fresh surgical specimens suitable for in vitro and in vivo studies.

Ray S, Langan RC, Mullinax JE, Koizumi T, Xin HW, Wiegand GW, Anderson AJ, Stojadinovic A, Thorgeirsson S, Rudloff U, Avital I.

J Cancer. 2012;3:196-206. doi: 10.7150/jca.4484. Epub 2012 May 7.

37.

Liver directed therapy for renal cell carcinoma.

Langan RC, Ripley RT, Davis JL, Prieto PA, Datrice N, Steinberg SM, Bratslavsky G, Rudloff U, Kammula US, Stojadinovic A, Avital I.

J Cancer. 2012;3:184-90. doi: 10.7150/jca.4456. Epub 2012 Apr 20.

38.

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma.

Wei X, Moncada-Pazos A, Cal S, Soria-Valles C, Gartner J, Rudloff U, Lin JC; NISC Comparative Sequencing Program, Rosenberg SA, López-Otín C, Samuels Y.

Hum Mutat. 2011 Jun;32(6):E2148-75. doi: 10.1002/humu.21477. Epub 2011 Feb 24.

39.

Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ.

Rudloff U, Jacks LM, Goldberg JI, Wynveen CA, Brogi E, Patil S, Van Zee KJ.

J Clin Oncol. 2010 Aug 10;28(23):3762-9. doi: 10.1200/JCO.2009.26.8847. Epub 2010 Jul 12.

PMID:
20625132
40.

A growing family: adding mutated Erbb4 as a novel cancer target.

Rudloff U, Samuels Y.

Cell Cycle. 2010 Apr 15;9(8):1487-503. Epub 2010 Apr 15.

41.

The influence of margin width and volume of disease near margin on benefit of radiation therapy for women with DCIS treated with breast-conserving therapy.

Rudloff U, Brogi E, Reiner AS, Goldberg JI, Brockway JP, Wynveen CA, McCormick B, Patil S, Van Zee KJ.

Ann Surg. 2010 Apr;251(4):583-91. doi: 10.1097/SLA.0b013e3181b5931e.

PMID:
20224381
42.

Biobanking of human pancreas cancer tissue: impact of ex-vivo procurement times on RNA quality.

Rudloff U, Bhanot U, Gerald W, Klimstra DS, Jarnagin WR, Brennan MF, Allen PJ.

Ann Surg Oncol. 2010 Aug;17(8):2229-36. doi: 10.1245/s10434-010-0959-6. Epub 2010 Feb 17.

43.

Randomized clinical trials in pancreatic adenocarcinoma.

Rudloff U, Maker AV, Brennan MF, Allen PJ.

Surg Oncol Clin N Am. 2010 Jan;19(1):115-50. doi: 10.1016/j.soc.2009.09.009. Review.

PMID:
19914563
44.

TYRO3-mediated regulation of MITF: a novel target in melanoma?

Rudloff U, Samuels Y.

Pigment Cell Melanoma Res. 2010 Feb;23(1):9-11. doi: 10.1111/j.1755-148X.2009.00649.x. Epub 2009 Oct 20. No abstract available.

45.

Concurrent lobular neoplasia increases the risk of ipsilateral breast cancer recurrence in patients with ductal carcinoma in situ treated with breast-conserving therapy.

Rudloff U, Brogi E, Brockway JP, Goldberg JI, Cranor M, Wynveen CA, Nehhozina T, Reiner AS, Patil S, Van Zee KJ.

Cancer. 2009 Mar 15;115(6):1203-14. doi: 10.1002/cncr.24166. Erratum in: Cancer. 2010 Apr 15;116(8):2064.

46.

Volvulus of an appendiceal mucocele: report of a case.

Rudloff U, Malhotra S.

Surg Today. 2007;37(6):514-7. Epub 2007 May 28.

PMID:
17522774
47.

Trauma in pregnancy.

Rudloff U.

Arch Gynecol Obstet. 2007 Aug;276(2):101-17. Review. No abstract available.

PMID:
17219159
48.

Adult-onset asthma and periocular xanthogranulomas in a patient with lymphoplasmacytic sclerosing pancreatitis.

Roggin KK, Rudloff U, Klimstra DS, Russell LA, Blumgart LH.

Pancreas. 2007 Jan;34(1):157-60.

PMID:
17198199
49.

Chirurgica Taurina: a 10-year experience of bullfight injuries.

Rudloff U, Gonzalez V, Fernandez E, Holguin E, Rubio G, Lomelin J, Dittmar M, Barrera R.

J Trauma. 2006 Oct;61(4):970-4.

PMID:
17033570
50.

Central pancreatectomy revisited.

Roggin KK, Rudloff U, Blumgart LH, Brennan MF.

J Gastrointest Surg. 2006 Jun;10(6):804-12.

PMID:
16769536

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