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Items: 1 to 50 of 219

1.

Roles of Regulatory T Cells in Tissue Pathophysiology and Metabolism.

Campbell C, Rudensky A.

Cell Metab. 2019 Oct 1. pii: S1550-4131(19)30513-3. doi: 10.1016/j.cmet.2019.09.010. [Epub ahead of print] Review.

PMID:
31607562
2.

IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus.

Hemmers S, Schizas M, Azizi E, Dikiy S, Zhong Y, Feng Y, Altan-Bonnet G, Rudensky AY.

J Exp Med. 2019 Aug 21. pii: jem.20190993. doi: 10.1084/jem.20190993. [Epub ahead of print]

PMID:
31434685
3.

Therapeutic use of regulatory T cells for graft-versus-host disease.

Elias S, Rudensky AY.

Br J Haematol. 2019 Oct;187(1):25-38. doi: 10.1111/bjh.16157. Epub 2019 Aug 16. Review.

PMID:
31418827
4.

Mouse Watch: A Cautionary Tale.

Dikiy S, Rudensky AY.

Immunity. 2019 Jul 16;51(1):10-12. doi: 10.1016/j.immuni.2019.06.019.

PMID:
31315029
5.

Editorial overview: The value of commitment in the lymphocyte world.

Rudensky AY.

Curr Opin Immunol. 2019 Jun;58:v-vii. doi: 10.1016/j.coi.2019.06.004. No abstract available.

PMID:
31279359
6.

Distinct Requirements of CHD4 during B Cell Development and Antibody Response.

Yen WF, Sharma R, Cols M, Lau CM, Chaudhry A, Chowdhury P, Yewdell WT, Vaidyanathan B, Sun A, Coffre M, Pucella JN, Chen CC, Jasin M, Sun JC, Rudensky AY, Koralov SB, Chaudhuri J.

Cell Rep. 2019 Apr 30;27(5):1472-1486.e5. doi: 10.1016/j.celrep.2019.04.011.

7.

Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells.

van der Veeken J, Zhong Y, Sharma R, Mazutis L, Dao P, Pe'er D, Leslie CS, Rudensky AY.

Immunity. 2019 May 21;50(5):1202-1217.e7. doi: 10.1016/j.immuni.2019.03.031. Epub 2019 Apr 23.

PMID:
31027997
8.

Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells.

Fleskens V, Minutti CM, Wu X, Wei P, Pals CEGM, McCrae J, Hemmers S, Groenewold V, Vos HJ, Rudensky A, Pan F, Li H, Zaiss DM, Coffer PJ.

Cell Rep. 2019 Mar 26;26(13):3600-3612.e6. doi: 10.1016/j.celrep.2019.02.087.

9.

A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.

Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA.

Immunity. 2019 Feb 19;50(2):362-377.e6. doi: 10.1016/j.immuni.2018.12.016. Epub 2019 Jan 29.

PMID:
30709738
10.

FoxP3 and Ezh2 regulate Tfr cell suppressive function and transcriptional program.

Hou S, Clement RL, Diallo A, Blazar BR, Rudensky AY, Sharpe AH, Sage PT.

J Exp Med. 2019 Mar 4;216(3):605-620. doi: 10.1084/jem.20181134. Epub 2019 Jan 31.

11.

Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function.

Konopacki C, Pritykin Y, Rubtsov Y, Leslie CS, Rudensky AY.

Nat Immunol. 2019 Feb;20(2):232-242. doi: 10.1038/s41590-018-0291-z. Epub 2019 Jan 14.

PMID:
30643266
12.

CD49b defines functionally mature Treg cells that survey skin and vascular tissues.

Fan X, Moltedo B, Mendoza A, Davydov AN, Faire MB, Mazutis L, Sharma R, Pe'er D, Chudakov DM, Rudensky AY.

J Exp Med. 2018 Nov 5;215(11):2796-2814. doi: 10.1084/jem.20181442. Epub 2018 Oct 24.

13.

The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types.

Hsin JP, Lu Y, Loeb GB, Leslie CS, Rudensky AY.

Nat Immunol. 2018 Oct;19(10):1137-1145. doi: 10.1038/s41590-018-0208-x. Epub 2018 Sep 17.

14.

Author Correction: An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses.

Mann M, Mehta A, Zhao JL, Lee K, Marinov GK, Garcia-Flores Y, Lu LF, Rudensky AY, Baltimore D.

Nat Commun. 2018 Aug 16;9(1):3338. doi: 10.1038/s41467-018-05720-5.

15.

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b.

Cho S, Lee HM, Yu IS, Choi YS, Huang HY, Hashemifar SS, Lin LL, Chen MC, Afanasiev ND, Khan AA, Lin SW, Rudensky AY, Crotty S, Lu LF.

Nat Commun. 2018 Jul 16;9(1):2757. doi: 10.1038/s41467-018-05196-3.

16.

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment.

Azizi E, Carr AJ, Plitas G, Cornish AE, Konopacki C, Prabhakaran S, Nainys J, Wu K, Kiseliovas V, Setty M, Choi K, Fromme RM, Dao P, McKenney PT, Wasti RC, Kadaveru K, Mazutis L, Rudensky AY, Pe'er D.

Cell. 2018 Aug 23;174(5):1293-1308.e36. doi: 10.1016/j.cell.2018.05.060. Epub 2018 Jun 28.

17.

Extrathymically Generated Regulatory T Cells Establish a Niche for Intestinal Border-Dwelling Bacteria and Affect Physiologic Metabolite Balance.

Campbell C, Dikiy S, Bhattarai SK, Chinen T, Matheis F, Calafiore M, Hoyos B, Hanash A, Mucida D, Bucci V, Rudensky AY.

Immunity. 2018 Jun 19;48(6):1245-1257.e9. doi: 10.1016/j.immuni.2018.04.013. Epub 2018 May 29.

18.

ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity.

Moore MJ, Blachere NE, Fak JJ, Park CY, Sawicka K, Parveen S, Zucker-Scharff I, Moltedo B, Rudensky AY, Darnell RB.

Elife. 2018 May 31;7. pii: e33057. doi: 10.7554/eLife.33057.

19.

Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU).

Li K, Vorkas CK, Chaudhry A, Bell DL, Willis RA, Rudensky A, Altman JD, Glickman MS, Aubé J.

PLoS One. 2018 Feb 5;13(2):e0191837. doi: 10.1371/journal.pone.0191837. eCollection 2018.

20.

Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade.

Ariyan CE, Brady MS, Siegelbaum RH, Hu J, Bello DM, Rand J, Fisher C, Lefkowitz RA, Panageas KS, Pulitzer M, Vignali M, Emerson R, Tipton C, Robins H, Merghoub T, Yuan J, Jungbluth A, Blando J, Sharma P, Rudensky AY, Wolchok JD, Allison JP.

Cancer Immunol Res. 2018 Feb;6(2):189-200. doi: 10.1158/2326-6066.CIR-17-0356. Epub 2018 Jan 16.

21.

Comparative analysis of murine T-cell receptor repertoires.

Izraelson M, Nakonechnaya TO, Moltedo B, Egorov ES, Kasatskaya SA, Putintseva EV, Mamedov IZ, Staroverov DB, Shemiakina II, Zakharova MY, Davydov AN, Bolotin DA, Shugay M, Chudakov DM, Rudensky AY, Britanova OV.

Immunology. 2018 Feb;153(2):133-144. doi: 10.1111/imm.12857. Epub 2017 Nov 27. Review.

22.

A nonimmune function of T cells in promoting lung tumor progression.

Green JA, Arpaia N, Schizas M, Dobrin A, Rudensky AY.

J Exp Med. 2017 Dec 4;214(12):3565-3575. doi: 10.1084/jem.20170356. Epub 2017 Oct 16.

23.

An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses.

Mann M, Mehta A, Zhao JL, Lee K, Marinov GK, Garcia-Flores Y, Lu LF, Rudensky AY, Baltimore D.

Nat Commun. 2017 Oct 11;8(1):851. doi: 10.1038/s41467-017-00972-z. Erratum in: Nat Commun. 2018 Aug 16;9(1):3338.

24.

Antigen receptor repertoire profiling from RNA-seq data.

Bolotin DA, Poslavsky S, Davydov AN, Frenkel FE, Fanchi L, Zolotareva OI, Hemmers S, Putintseva EV, Obraztsova AS, Shugay M, Ataullakhanov RI, Rudensky AY, Schumacher TN, Chudakov DM.

Nat Biotechnol. 2017 Oct 11;35(10):908-911. doi: 10.1038/nbt.3979. No abstract available.

25.

Corrigendum: Stability and function of regulatory T cells expressing the transcription factor T-bet.

Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY.

Nature. 2017 Sep 20;550(7674):142. doi: 10.1038/nature24013.

PMID:
28953866
26.

BRCT-domain protein BRIT1 influences class switch recombination.

Yen WF, Chaudhry A, Vaidyanathan B, Yewdell WT, Pucella JN, Sharma R, Liang Y, Li K, Rudensky AY, Chaudhuri J.

Proc Natl Acad Sci U S A. 2017 Jul 19. pii: 201708211. doi: 10.1073/pnas.1708211114. [Epub ahead of print]

27.

Stability and function of regulatory T cells expressing the transcription factor T-bet.

Levine AG, Mendoza A, Hemmers S, Moltedo B, Niec RE, Schizas M, Hoyos BE, Putintseva EV, Chaudhry A, Dikiy S, Fujisawa S, Chudakov DM, Treuting PM, Rudensky AY.

Nature. 2017 Jun 15;546(7658):421-425. doi: 10.1038/nature22360. Epub 2017 Jun 7. Erratum in: Nature. 2017 Sep 20;:.

28.

Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity.

Levine AG, Hemmers S, Baptista AP, Schizas M, Faire MB, Moltedo B, Konopacki C, Schmidt-Supprian M, Germain RN, Treuting PM, Rudensky AY.

J Exp Med. 2017 Mar 6;214(3):609-622. doi: 10.1084/jem.20161318. Epub 2017 Jan 27.

29.

Pillars Article: Foxp3 Programs the Development and Function of CD4+CD25+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330-336.

Fontenot JD, Gavin MA, Rudensky AY.

J Immunol. 2017 Feb 1;198(3):986-992. No abstract available.

30.

The aryl hydrocarbon receptor controls cell-fate decisions in B cells.

Vaidyanathan B, Chaudhry A, Yewdell WT, Angeletti D, Yen WF, Wheatley AK, Bradfield CA, McDermott AB, Yewdell JW, Rudensky AY, Chaudhuri J.

J Exp Med. 2017 Jan;214(1):197-208. doi: 10.1084/jem.20160789. Epub 2016 Dec 23.

31.

Basophils Promote Tumor Rejection via Chemotaxis and Infiltration of CD8+ T Cells.

Sektioglu IM, Carretero R, Bulbuc N, Bald T, Tüting T, Rudensky AY, Hämmerling GJ.

Cancer Res. 2017 Jan 15;77(2):291-302. doi: 10.1158/0008-5472.CAN-16-0993. Epub 2016 Nov 22.

32.

Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer.

Plitas G, Konopacki C, Wu K, Bos PD, Morrow M, Putintseva EV, Chudakov DM, Rudensky AY.

Immunity. 2016 Nov 15;45(5):1122-1134. doi: 10.1016/j.immuni.2016.10.032.

33.

An essential role for the IL-2 receptor in Treg cell function.

Chinen T, Kannan AK, Levine AG, Fan X, Klein U, Zheng Y, Gasteiger G, Feng Y, Fontenot JD, Rudensky AY.

Nat Immunol. 2016 Nov;17(11):1322-1333. doi: 10.1038/ni.3540. Epub 2016 Sep 5.

34.

Regulatory T Cells: Differentiation and Function.

Plitas G, Rudensky AY.

Cancer Immunol Res. 2016 Sep 2;4(9):721-5. doi: 10.1158/2326-6066.CIR-16-0193. Review.

35.

Memory of Inflammation in Regulatory T Cells.

van der Veeken J, Gonzalez AJ, Cho H, Arvey A, Hemmers S, Leslie CS, Rudensky AY.

Cell. 2016 Aug 11;166(4):977-990. doi: 10.1016/j.cell.2016.07.006. Epub 2016 Aug 4.

36.

T cell receptor signalling in the control of regulatory T cell differentiation and function.

Li MO, Rudensky AY.

Nat Rev Immunol. 2016 Apr;16(4):220-33. doi: 10.1038/nri.2016.26. Review.

37.

Hallmarks of Tissue-Resident Lymphocytes.

Fan X, Rudensky AY.

Cell. 2016 Mar 10;164(6):1198-1211. doi: 10.1016/j.cell.2016.02.048. Review.

38.

miR-23∼27∼24 clusters control effector T cell differentiation and function.

Cho S, Wu CJ, Yasuda T, Cruz LO, Khan AA, Lin LL, Nguyen DT, Miller M, Lee HM, Kuo ML, Broide DH, Rajewsky K, Rudensky AY, Lu LF.

J Exp Med. 2016 Feb 8;213(2):235-49. doi: 10.1084/jem.20150990. Epub 2016 Feb 1.

39.

Pillars Article: Sequence Analysis of Peptides Bound to MHC Class II Molecules. Nature. 1991. 353: 622-627.

Rudensky AY, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA Jr.

J Immunol. 2016 Feb 1;196(3):941-6. No abstract available.

40.

A mechanism for expansion of regulatory T-cell repertoire and its role in self-tolerance.

Feng Y, van der Veeken J, Shugay M, Putintseva EV, Osmanbeyoglu HU, Dikiy S, Hoyos BE, Moltedo B, Hemmers S, Treuting P, Leslie CS, Chudakov DM, Rudensky AY.

Nature. 2015 Dec 3;528(7580):132-136. doi: 10.1038/nature16141. Epub 2015 Nov 25.

41.

Immune homeostasis enforced by co-localized effector and regulatory T cells.

Liu Z, Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN.

Nature. 2015 Dec 10;528(7581):225-30. doi: 10.1038/nature16169. Epub 2015 Nov 25.

42.

Genetic and epigenetic variation in the lineage specification of regulatory T cells.

Arvey A, van der Veeken J, Plitas G, Rich SS, Concannon P, Rudensky AY.

Elife. 2015 Oct 28;4:e07571. doi: 10.7554/eLife.07571.

43.

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs.

Gasteiger G, Fan X, Dikiy S, Lee SY, Rudensky AY.

Science. 2015 Nov 20;350(6263):981-5. doi: 10.1126/science.aac9593. Epub 2015 Oct 15.

44.

Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity.

Paterson AM, Lovitch SB, Sage PT, Juneja VR, Lee Y, Trombley JD, Arancibia-Cárcamo CV, Sobel RA, Rudensky AY, Kuchroo VK, Freeman GJ, Sharpe AH.

J Exp Med. 2015 Sep 21;212(10):1603-21. doi: 10.1084/jem.20141030. Epub 2015 Sep 14.

45.

A Distinct Function of Regulatory T Cells in Tissue Protection.

Arpaia N, Green JA, Moltedo B, Arvey A, Hemmers S, Yuan S, Treuting PM, Rudensky AY.

Cell. 2015 Aug 27;162(5):1078-89. doi: 10.1016/j.cell.2015.08.021.

46.

A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner.

Lu LF, Gasteiger G, Yu IS, Chaudhry A, Hsin JP, Lu Y, Bos PD, Lin LL, Zawislak CL, Cho S, Sun JC, Leslie CS, Lin SW, Rudensky AY.

Immunity. 2015 Jul 21;43(1):52-64. doi: 10.1016/j.immuni.2015.04.022. Epub 2015 Jul 7.

47.

Reigning in regulatory T-cell function.

Konopacki C, Plitas G, Rudensky A.

Nat Biotechnol. 2015 Jul;33(7):718-9. doi: 10.1038/nbt.3285. No abstract available.

PMID:
26154011
48.

DNA methylation secures CD4(+) and CD8(+) T cell lineage borders.

Feng Y, Rudensky AY.

Nat Immunol. 2015 Jul;16(7):681-3. doi: 10.1038/ni.3207. No abstract available.

PMID:
26086134
49.

The Cell-Intrinsic Circadian Clock Is Dispensable for Lymphocyte Differentiation and Function.

Hemmers S, Rudensky AY.

Cell Rep. 2015 Jun 9;11(9):1339-49. doi: 10.1016/j.celrep.2015.04.058. Epub 2015 May 21.

50.

Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.

Vierstra J, Rynes E, Sandstrom R, Zhang M, Canfield T, Hansen RS, Stehling-Sun S, Sabo PJ, Byron R, Humbert R, Thurman RE, Johnson AK, Vong S, Lee K, Bates D, Neri F, Diegel M, Giste E, Haugen E, Dunn D, Wilken MS, Josefowicz S, Samstein R, Chang KH, Eichler EE, De Bruijn M, Reh TA, Skoultchi A, Rudensky A, Orkin SH, Papayannopoulou T, Treuting PM, Selleri L, Kaul R, Groudine M, Bender MA, Stamatoyannopoulos JA.

Science. 2014 Nov 21;346(6212):1007-12. doi: 10.1126/science.1246426.

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