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Items: 1 to 50 of 511

1.

Theria-specific homeodomain and cis-regulatory element evolution of the Dlx3-4 bigene cluster in 12 different mammalian species.

Sumiyama K, Miyake T, Grimwood J, Stuart A, Dickson M, Schmutz J, Ruddle FH, Myers RM, Amemiya CT.

J Exp Zool B Mol Dev Evol. 2012 Dec;318(8):639-50. doi: 10.1002/jez.b.22469. Epub 2012 Sep 5.

2.

High endothelial venule reporter mice to probe regulation of lymph node vasculature.

Bentley KL, Stranford S, Liao S, Mounzer RM, Ruddle FH, Ruddle NH.

Adv Exp Med Biol. 2011;691:35-44. doi: 10.1007/978-1-4419-6612-4_4. No abstract available.

PMID:
21153307
3.

A yeast-based recombinogenic targeting toolset for transgenic analysis of human disease genes.

Bentley KL, Shashikant CS, Wang W, Ruddle NH, Ruddle FH.

Ann N Y Acad Sci. 2010 Oct;1207 Suppl 1:E58-68. doi: 10.1111/j.1749-6632.2010.05712.x.

PMID:
20961307
4.

Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome.

Amemiya CT, Powers TP, Prohaska SJ, Grimwood J, Schmutz J, Dickson M, Miyake T, Schoenborn MA, Myers RM, Ruddle FH, Stadler PF.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3622-7. doi: 10.1073/pnas.0914312107. Epub 2010 Feb 5.

5.

Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development.

Enkhmandakh B, Makeyev AV, Erdenechimeg L, Ruddle FH, Chimge NO, Tussie-Luna MI, Roy AL, Bayarsaihan D.

Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):181-6. doi: 10.1073/pnas.0811531106. Epub 2008 Dec 24.

6.

Identification of the TFII-I family target genes in the vertebrate genome.

Chimge NO, Makeyev AV, Ruddle FH, Bayarsaihan D.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9006-10. doi: 10.1073/pnas.0803051105. Epub 2008 Jun 25.

7.

Transgenic LacZ under control of Hec-6st regulatory sequences recapitulates endogenous gene expression on high endothelial venules.

Liao S, Bentley K, Lebrun M, Lesslauer W, Ruddle FH, Ruddle NH.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4577-82. Epub 2007 Mar 5.

8.

Mouse naked cuticle 2 (mNkd2) as a direct transcriptional target of Hoxc8 in vivo.

Lei H, Juan AH, Kim MS, Ruddle FH.

J Exp Zool A Ecol Genet Physiol. 2007 Jan 1;307(1):1-6.

PMID:
17094106
9.

Multiple roles of hoxc8 in skeletal development.

Juan AH, Lei H, Bhargava P, Lebrun M, Ruddle FH.

Ann N Y Acad Sci. 2006 Apr;1068:87-94.

PMID:
16831908
10.

Identification of a Hoxc8-regulated transcriptional network in mouse embryo fibroblast cells.

Lei H, Juan AH, Kim MS, Ruddle FH.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10305-10309. doi: 10.1073/pnas.0603552103. Epub 2006 Jun 22.

11.

HnRNP A3 genes and pseudogenes in the vertebrate genomes.

Makeyev AV, Kim CB, Ruddle FH, Enkhmandakh B, Erdenechimeg L, Bayarsaihan D.

J Exp Zool A Comp Exp Biol. 2005 Apr 1;303(4):259-71.

PMID:
15776420
12.

The identification of Hoxc8 target genes.

Lei H, Wang H, Juan AH, Ruddle FH.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2420-4. Epub 2005 Feb 7.

13.

Evidence for independent Hox gene duplications in the hagfish lineage: a PCR-based gene inventory of Eptatretus stoutii.

Stadler PF, Fried C, Prohaska SJ, Bailey WJ, Misof BY, Ruddle FH, Wagner GP.

Mol Phylogenet Evol. 2004 Sep;32(3):686-94.

PMID:
15288047
14.

GTF2IRD2 is located in the Williams-Beuren syndrome critical region 7q11.23 and encodes a protein with two TFII-I-like helix-loop-helix repeats.

Makeyev AV, Erdenechimeg L, Mungunsukh O, Roth JJ, Enkhmandakh B, Ruddle FH, Bayarsaihan D.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11052-7. Epub 2004 Jul 8.

15.

Theophilus Painter: First steps toward an understanding of the human genome.

Ruddle FH.

J Exp Zool A Comp Exp Biol. 2004 May 1;301(5):375-7. No abstract available.

PMID:
15114644
16.

The shark HoxN cluster is homologous to the human HoxD cluster.

Prohaska SJ, Fried C, Amemiya CT, Ruddle FH, Wagner GP, Stadler PF.

J Mol Evol. 2004 Feb;58(2):212-7.

PMID:
15042342
17.

Homeoprotein DLX-1 interacts with Smad4 and blocks a signaling pathway from activin A in hematopoietic cells.

Chiba S, Takeshita K, Imai Y, Kumano K, Kurokawa M, Masuda S, Shimizu K, Nakamura S, Ruddle FH, Hirai H.

Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15577-82. Epub 2003 Dec 11.

18.

Homez, a homeobox leucine zipper gene specific to the vertebrate lineage.

Bayarsaihan D, Enkhmandakh B, Makeyev A, Greally JM, Leckman JF, Ruddle FH.

Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10358-63. Epub 2003 Aug 18.

19.

Enhancer timing of Hox gene expression: deletion of the endogenous Hoxc8 early enhancer.

Juan AH, Ruddle FH.

Development. 2003 Oct;130(20):4823-34. Epub 2003 Aug 13.

20.

Impact of transgenic technologies on functional genomics.

Shashikant CS, Ruddle FH.

Curr Issues Mol Biol. 2003 Jul;5(3):75-98. Review.

21.

Phylogenetic analysis of the mammalian Hoxc8 non-coding region.

Kim CB, Shashikant CS, Sumiyama K, Wang WC, Amemiya CT, Ruddle FH.

J Struct Funct Genomics. 2003;3(1-4):195-9.

PMID:
12836698
22.

The role of gene duplication in the evolution and function of the vertebrate Dlx/distal-less bigene clusters.

Sumiyama K, Irvine SQ, Ruddle FH.

J Struct Funct Genomics. 2003;3(1-4):151-9. Review.

PMID:
12836694
23.

Regulation of Dlx3 gene expression in visceral arches by evolutionarily conserved enhancer elements.

Sumiyama K, Ruddle FH.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4030-4. Epub 2003 Mar 17.

24.

Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxbeta.

Tussié-Luna MI, Bayarsaihan D, Seto E, Ruddle FH, Roy AL.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12807-12. Epub 2002 Sep 18.

25.

Characterization of Hox genes in the bichir, Polypterus palmas.

Ledje C, Kim CB, Ruddle FH.

J Exp Zool. 2002 Aug 15;294(2):107-11.

PMID:
12210111
26.

Molecular evolution of the HoxA cluster in the three major gnathostome lineages.

Chiu CH, Amemiya C, Dewar K, Kim CB, Ruddle FH, Wagner GP.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5492-7. Epub 2002 Apr 9.

27.

Genomic analysis of Hox clusters in the sea lamprey Petromyzon marinus.

Irvine SQ, Carr JL, Bailey WJ, Kawasaki K, Shimizu N, Amemiya CT, Ruddle FH.

J Exp Zool. 2002 Apr 15;294(1):47-62.

PMID:
11932948
28.

Genomic organization of the genes Gtf2ird1, Gtf2i, and Ncf1 at the mouse chromosome 5 region syntenic to the human chromosome 7q11.23 Williams syndrome critical region.

Bayarsaihan D, Dunai J, Greally JM, Kawasaki K, Sumiyama K, Enkhmandakh B, Shimizu N, Ruddle FH.

Genomics. 2002 Jan;79(1):137-43.

PMID:
11827466
29.

Genomic structure and functional control of the Dlx3-7 bigene cluster.

Sumiyama K, Irvine SQ, Stock DW, Weiss KM, Kawasaki K, Shimizu N, Shashikant CS, Miller W, Ruddle FH.

Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):780-5. Epub 2002 Jan 15.

30.

Repression of TFII-I-dependent transcription by nuclear exclusion.

Tussié-Luna MI, Bayarsaihan D, Ruddle FH, Roy AL.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7789-94.

31.
32.
33.

A recombinogenic targeting method to modify large-inserts for cis-regulatory analysis in transgenic mice: construction and expression of a 100-kb, zebrafish Hoxa-11b-lacZ reporter gene.

Chiu CH, Amemiya CT, Carr JL, Bhargava J, Hwang JK, Shashikant CS, Ruddle FH, Wagner GP.

Dev Genes Evol. 2000 Feb;210(2):105-9.

PMID:
10664153
34.

Direct cloning of genomic DNA by recombinogenic targeting method using a yeast-bacterial shuttle vector, pClasper.

Bhargava J, Shashikant CS, Carr JL, Juan H, Bentley KL, Ruddle FH.

Genomics. 1999 Dec 1;62(2):285-8.

PMID:
10610723
35.

Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development.

Hanson RD, Hess JL, Yu BD, Ernst P, van Lohuizen M, Berns A, van der Lugt NM, Shashikant CS, Ruddle FH, Seto M, Korsmeyer SJ.

Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14372-7.

36.

Ksp-cadherin gene promoter. II. Kidney-specific activity in transgenic mice.

Igarashi P, Shashikant CS, Thomson RB, Whyte DA, Liu-Chen S, Ruddle FH, Aronson PS.

Am J Physiol. 1999 Oct;277(4):F599-610. doi: 10.1152/ajprenal.1999.277.4.F599.

PMID:
10516285
37.

Evolution of chordate hox gene clusters.

Ruddle FH, Amemiya CT, Carr JL, Kim CB, Ledje C, Shashikant CS, Wagner GP.

Ann N Y Acad Sci. 1999 May 18;870:238-48.

PMID:
10415487
38.

Phylogenetically conserved CK-II phosphorylation site of the murine homeodomain protein Hoxb-6.

Fienberg AA, Nordstedt C, Belting HG, Czernik AJ, Nairn AC, Gandy S, Greengard P, Ruddle FH.

J Exp Zool. 1999 Apr 15;285(1):76-84.

PMID:
10327653
39.

pPAC-ResQ: A yeast-bacterial shuttle vector for capturing inserts from P1 and PAC clones by recombinogenic targeted cloning.

Bhargava J, Shashikant CS, Carr JL, Bentley KL, Amemiya CT, Ruddle FH.

Genomics. 1999 Mar 15;56(3):337-9.

PMID:
10087201
40.

Mapping and sequencing of the human genome.

Ruddle FH.

Jpn J Cancer Res. 1998 Dec;89(12):inside front cover. No abstract available.

PMID:
10081483
41.

Comparative studies on mammalian Hoxc8 early enhancer sequence reveal a baleen whale-specific deletion of a cis-acting element.

Shashikant CS, Kim CB, Borbély MA, Wang WC, Ruddle FH.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15446-51.

42.

Recombinogenic targeting: a new approach to genomic analysis--a review.

Shashikant CS, Carr JL, Bhargava J, Bentley KL, Ruddle FH.

Gene. 1998 Nov 26;223(1-2):9-20. Review.

PMID:
9858667
43.

Multiple phases of expression and regulation of mouse Hoxc8 during early embryogenesis.

Belting HG, Shashikant CS, Ruddle FH.

J Exp Zool. 1998 Sep-Oct 1;282(1-2):196-222.

PMID:
9723177
44.

Modification of expression and cis-regulation of Hoxc8 in the evolution of diverged axial morphology.

Belting HG, Shashikant CS, Ruddle FH.

Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2355-60.

45.

Molecular evolution of Hox gene regulation: cloning and transgenic analysis of the lamprey HoxQ8 gene.

Carr JL, Shashikant CS, Bailey WJ, Ruddle FH.

J Exp Zool. 1998 Jan 1;280(1):73-85.

PMID:
9437854
46.

Vertebrate genome evolution--the decade ahead.

Ruddle FH.

Genomics. 1997 Dec 1;46(2):171-3. Review. No abstract available.

PMID:
9417903
47.

Phylogenetic reconstruction of vertebrate Hox cluster duplications.

Bailey WJ, Kim J, Wagner GP, Ruddle FH.

Mol Biol Evol. 1997 Aug;14(8):843-53.

PMID:
9254922
48.
49.

Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosis.

Shimamoto T, Nakamura S, Bollekens J, Ruddle FH, Takeshita K.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3245-9.

50.

Genomic analysis of a new mammalian distal-less gene: Dlx7.

Nakamura S, Stock DW, Wydner KL, Bollekens JA, Takeshita K, Nagai BM, Chiba S, Kitamura T, Freeland TM, Zhao Z, Minowada J, Lawrence JB, Weiss KM, Ruddle FH.

Genomics. 1996 Dec 15;38(3):314-24.

PMID:
8975708

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