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In Vivo Retargeting of Poly(beta aminoester) (OM-PBAE) Nanoparticles is Influenced by Protein Corona.

Fornaguera C, Guerra-Rebollo M, Lázaro MÁ, Cascante A, Rubio N, Blanco J, Borrós S.

Adv Healthc Mater. 2019 Oct;8(19):e1900849. doi: 10.1002/adhm.201900849. Epub 2019 Sep 2.


Theiler's murine encephalomyelitis virus infection of astrocytes induces the expression of chemokines which attract activated but not resting T lymphocytes.

Rubio N, Sanz-Rodriguez F.

J Neurovirol. 2019 Jul 5. doi: 10.1007/s13365-019-00776-5. [Epub ahead of print]


Targeting of replicating CD133 and OCT4/SOX2 expressing glioma stem cells selects a cell population that reinitiates tumors upon release of therapeutic pressure.

Guerra-Rebollo M, Garrido C, Sánchez-Cid L, Soler-Botija C, Meca-Cortés O, Rubio N, Blanco J.

Sci Rep. 2019 Jul 2;9(1):9549. doi: 10.1038/s41598-019-46014-0.


Discrimination between chewing of coca leaves or drinking of coca tea and smoking of "paco" (coca paste) by hair analysis. A preliminary study of possibilities and limitations.

Rubio NC, Krumbiegel F, Pragst F, Thurmann D, Nagel A, Zytowski E, Aranguren M, Gorlelo JC, Poliansky N.

Forensic Sci Int. 2019 Apr;297:171-176. doi: 10.1016/j.forsciint.2019.01.040. Epub 2019 Feb 5.


The Turner syndrome research registry: Creating equipoise between investigators and participants.

Prakash SK, Lugo-Ruiz S, Rivera-Dávila M, Rubio N Jr, Shah AN, Knickmeyer RC, Scurlock C, Crenshaw M, Davis SM, Lorigan GA, Dorfman AT, Rubin K, Maslen C, Bamba V, Kruszka P, Silberbach M; Scientific Advisory Board of the TSRR.

Am J Med Genet C Semin Med Genet. 2019 Mar;181(1):135-140. doi: 10.1002/ajmg.c.31689. Epub 2019 Feb 13.


Smartphone-Based Physical Activity Telecoaching in Chronic Obstructive Pulmonary Disease: Mixed-Methods Study on Patient Experiences and Lessons for Implementation.

Loeckx M, Rabinovich RA, Demeyer H, Louvaris Z, Tanner R, Rubio N, Frei A, De Jong C, Gimeno-Santos E, Rodrigues FM, Buttery SC, Hopkinson NS, Büsching G, Strassmann A, Serra I, Vogiatzis I, Garcia-Aymerich J, Polkey MI, Troosters T.

JMIR Mhealth Uhealth. 2018 Dec 21;6(12):e200. doi: 10.2196/mhealth.9774.


Depleting Depletion: Maintaining Single-Walled Carbon Nanotube Dispersions after Graft-To Polymer Functionalization.

Clancy AJ, Leese HS, Rubio N, Buckley DJ, Greenfield JL, Shaffer MSP.

Langmuir. 2018 Dec 18;34(50):15396-15402. doi: 10.1021/acs.langmuir.8b03144. Epub 2018 Nov 28.


Development of a Reliable Method for Assessing Coca Alkaloids in Oral Fluid by HPLC-MS-MS.

Rubio NC, Bermejo-Barrera P, Bermejo AM, Moreda-Piñeiro A.

J Anal Toxicol. 2019 Apr 1;43(3):196-202. doi: 10.1093/jat/bky076.


Glioblastoma Bystander Cell Therapy: Improvements in Treatment and Insights into the Therapy Mechanisms.

Guerra-Rebollo M, Nogueira de Moraes C, Alcoholado C, Soler-Botija C, Sanchez-Cid L, Vila OF, Meca-Cortés O, Ramos-Romero S, Rubio N, Becerra J, Blanco J, Garrido C.

Mol Ther Oncolytics. 2018 Sep 15;11:39-51. doi: 10.1016/j.omto.2018.09.002. eCollection 2018 Dec 21.


Fast Exfoliation and Functionalisation of Two-Dimensional Crystalline Carbon Nitride by Framework Charging.

Jia J, White ER, Clancy AJ, Rubio N, Suter T, Miller TS, McColl K, McMillan PF, Brázdová V, Corà F, Howard CA, Law RV, Mattevi C, Shaffer MSP.

Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12656-12660. doi: 10.1002/anie.201800875. Epub 2018 Aug 29.


mRNA Delivery System for Targeting Antigen-Presenting Cells In Vivo.

Fornaguera C, Guerra-Rebollo M, Ángel Lázaro M, Castells-Sala C, Meca-Cortés O, Ramos-Pérez V, Cascante A, Rubio N, Blanco J, Borrós S.

Adv Healthc Mater. 2018 Sep;7(17):e1800335. doi: 10.1002/adhm.201800335. Epub 2018 Jun 19.


Kir 4.1 inward rectifier potassium channel is upregulated in astrocytes in a murine multiple sclerosis model.

Mercado F, Almanza A, Rubio N, Soto E.

Neurosci Lett. 2018 Jun 11;677:88-93. doi: 10.1016/j.neulet.2018.04.052. Epub 2018 Apr 26.


Modeling of behavioral responses for successful selection of easy-to-train rams for semen collection with an artificial vagina.

Ambrosi CP, Rubio N, Giménez G, Venturino A, Aisen EG, López Armengol MF.

Anim Reprod Sci. 2018 Jun;193:90-97. doi: 10.1016/j.anireprosci.2018.04.003. Epub 2018 Apr 7.


Brominated graphene as a versatile precursor for multifunctional grafting.

Au H, Rubio N, Shaffer MSP.

Chem Sci. 2017 Sep 29;9(1):209-217. doi: 10.1039/c7sc03455e. eCollection 2018 Jan 7.


Application of an assay Cascade methodology for a deep preclinical characterization of polymeric nanoparticles as a treatment for gliomas.

Fornaguera C, Lázaro MÁ, Brugada-Vilà P, Porcar I, Morera I, Guerra-Rebollo M, Garrido C, Rubio N, Blanco J, Cascante A, Borrós S.

Drug Deliv. 2018 Nov;25(1):472-483. doi: 10.1080/10717544.2018.1436099.


MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells.

Sánchez-Cid L, Pons M, Lozano JJ, Rubio N, Guerra-Rebollo M, Soriano A, Paris-Coderch L, Segura MF, Fueyo R, Arguimbau J, Zodda E, Bermudo R, Alonso I, Caparrós X, Cascante M, Rafii A, Kang Y, Martínez-Balbás M, Weiss SJ, Blanco J, Muñoz M, Fernández PL, Thomson TM.

Oncotarget. 2017 Sep 7;8(48):83384-83406. doi: 10.18632/oncotarget.20698. eCollection 2017 Oct 13.


Thermochemical functionalisation of graphenes with minimal framework damage.

Hu S, Laker ZPL, Leese HS, Rubio N, De Marco M, Au H, Skilbeck MS, Wilson NR, Shaffer MSP.

Chem Sci. 2017 Sep 1;8(9):6149-6154. doi: 10.1039/c6sc05603b. Epub 2017 Jun 16.


CRISPR/Cas9-Mediated Knockin Application in Cell Therapy: A Non-viral Procedure for Bystander Treatment of Glioma in Mice.

Meca-Cortés O, Guerra-Rebollo M, Garrido C, Borrós S, Rubio N, Blanco J.

Mol Ther Nucleic Acids. 2017 Sep 15;8:395-403. doi: 10.1016/j.omtn.2017.07.012. Epub 2017 Jul 18.


Communication skills in candidates for accreditation in rheumatology are correlated with candidate's performance in the objective structured clinical examination.

Pascual-Ramos V, Flores-Alvarado DE, Portela-Hernández M, Maldonado-Velázquez MDR, Amezcua-Guerra LM, López-Zepeda J, Álvarez E, Rubio N, Lastra OV, Saavedra MÁ, Arce-Salinas CA; A.C. Consejo Mexicano de Reumatología.

Reumatol Clin. 2019 Mar - Apr;15(2):97-101. doi: 10.1016/j.reuma.2017.06.007. Epub 2017 Jul 26. English, Spanish.


Home monitoring of breathing rate in people with chronic obstructive pulmonary disease: observational study of feasibility, acceptability, and change after exacerbation.

Rubio N, Parker RA, Drost EM, Pinnock H, Weir CJ, Hanley J, Mantoani LC, MacNee W, McKinstry B, Rabinovich RA.

Int J Chron Obstruct Pulmon Dis. 2017 Apr 20;12:1221-1231. doi: 10.2147/COPD.S120706. eCollection 2017.


Physical activity is increased by a 12-week semiautomated telecoaching programme in patients with COPD: a multicentre randomised controlled trial.

Demeyer H, Louvaris Z, Frei A, Rabinovich RA, de Jong C, Gimeno-Santos E, Loeckx M, Buttery SC, Rubio N, Van der Molen T, Hopkinson NS, Vogiatzis I, Puhan MA, Garcia-Aymerich J, Polkey MI, Troosters T; Mr Papp PROactive study group and the PROactive consortium.

Thorax. 2017 May;72(5):415-423. doi: 10.1136/thoraxjnl-2016-209026. Epub 2017 Jan 30.


Application of Mixed Effects Limits of Agreement in the Presence of Multiple Sources of Variability: Exemplar from the Comparison of Several Devices to Measure Respiratory Rate in COPD Patients.

Parker RA, Weir CJ, Rubio N, Rabinovich R, Pinnock H, Hanley J, McCloughan L, Drost EM, Mantoani LC, MacNee W, McKinstry B.

PLoS One. 2016 Dec 14;11(12):e0168321. doi: 10.1371/journal.pone.0168321. eCollection 2016.


Novel homozygous likely-pathogenic intronic variant in INS causing permanent neonatal diabetes in siblings.

Courtney R, Gamble C, Arango ML, Shah A, Rubio NI, Nguyen J, Rodriguez-Buritica D.

J Pediatr Endocrinol Metab. 2016 Sep 1;29(9):1089-93. doi: 10.1515/jpem-2016-0040.


Real-Time Bioluminescence Imaging of Cell Distribution, Growth, and Differentiation in a Three-Dimensional Scaffold Under Interstitial Perfusion for Tissue Engineering.

Vila OF, Garrido C, Cano I, Guerra-Rebollo M, Navarro M, Meca-Cortés O, Ma SP, Engel E, Rubio N, Blanco J.

Tissue Eng Part C Methods. 2016 Sep;22(9):864-72. doi: 10.1089/ten.TEC.2014.0421. Epub 2016 Aug 10.


Interventions to modify physical activity in patients with COPD: a systematic review.

Mantoani LC, Rubio N, McKinstry B, MacNee W, Rabinovich RA.

Eur Respir J. 2016 Jul;48(1):69-81. doi: 10.1183/13993003.01744-2015. Epub 2016 Apr 21. Review.


Behaviour of hygrine and cuscohygrine in illicit cocaine production establishes their use as markers for chewing coca leaves in contrast with cocaine abuse.

Rubio NC, Thurmann D, Krumbiegel F, Pragst F.

Drug Test Anal. 2017 Feb;9(2):323-326. doi: 10.1002/dta.1972. Epub 2016 Mar 22.


Triple-Modal Imaging of Magnetically-Targeted Nanocapsules in Solid Tumours In Vivo.

Bai J, Wang JT, Rubio N, Protti A, Heidari H, Elgogary R, Southern P, Al-Jamal WT, Sosabowski J, Shah AM, Bals S, Pankhurst QA, Al-Jamal KT.

Theranostics. 2016 Jan 1;6(3):342-56. doi: 10.7150/thno.11918. eCollection 2016.


Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo.

Kafa H, Wang JT, Rubio N, Klippstein R, Costa PM, Hassan HA, Sosabowski JK, Bansal SS, Preston JE, Abbott NJ, Al-Jamal KT.

J Control Release. 2016 Mar 10;225:217-29. doi: 10.1016/j.jconrel.2016.01.031. Epub 2016 Jan 23.


Carbon nanotubes' surface chemistry determines their potency as vaccine nanocarriers in vitro and in vivo.

Hassan HA, Smyth L, Rubio N, Ratnasothy K, Wang JT, Bansal SS, Summers HD, Diebold SS, Lombardi G, Al-Jamal KT.

J Control Release. 2016 Mar 10;225:205-16. doi: 10.1016/j.jconrel.2016.01.030. Epub 2016 Jan 21.


Kinetics of functionalised carbon nanotube distribution in mouse brain after systemic injection: Spatial to ultra-structural analyses.

Wang JT, Rubio N, Kafa H, Venturelli E, Fabbro C, Ménard-Moyon C, Da Ros T, Sosabowski JK, Lawson AD, Robinson MK, Prato M, Bianco A, Festy F, Preston JE, Kostarelos K, Al-Jamal KT.

J Control Release. 2016 Feb 28;224:22-32. doi: 10.1016/j.jconrel.2015.12.039. Epub 2015 Dec 30.


Overexpression of caspase 1 in apoptosis-resistant astrocytes infected with the BeAn Theiler's virus.

Rubio N, Sanz-Rodriguez F.

J Neurovirol. 2016 Jun;22(3):316-26. doi: 10.1007/s13365-015-0400-9. Epub 2015 Nov 13.


In Vitro and in Vivo Demonstration of Photodynamic Activity and Cytoplasm Imaging through TPE Nanoparticles.

Jayaram DT, Ramos-Romero S, Shankar BH, Garrido C, Rubio N, Sanchez-Cid L, Gómez SB, Blanco J, Ramaiah D.

ACS Chem Biol. 2016 Jan 15;11(1):104-12. doi: 10.1021/acschembio.5b00537. Epub 2015 Nov 4.


Synthesis of double-clickable functionalised graphene oxide for biological applications.

Mei KC, Rubio N, Costa PM, Kafa H, Abbate V, Festy F, Bansal SS, Hider RC, Al-Jamal KT.

Chem Commun (Camb). 2015 Oct 18;51(81):14981-4. doi: 10.1039/c5cc05412e.


Solvent-Free Click-Mechanochemistry for the Preparation of Cancer Cell Targeting Graphene Oxide.

Rubio N, Mei KC, Klippstein R, Costa PM, Hodgins N, Wang JT, Festy F, Abbate V, Hider RC, Chan KL, Al-Jamal KT.

ACS Appl Mater Interfaces. 2015 Sep 2;7(34):18920-3. doi: 10.1021/acsami.5b06250. Epub 2015 Aug 20.


Passively Targeted Curcumin-Loaded PEGylated PLGA Nanocapsules for Colon Cancer Therapy In Vivo.

Klippstein R, Wang JT, El-Gogary RI, Bai J, Mustafa F, Rubio N, Bansal S, Al-Jamal WT, Al-Jamal KT.

Small. 2015 Sep;11(36):4704-22. doi: 10.1002/smll.201403799. Epub 2015 Jul 3.


Cationic Liposome- Multi-Walled Carbon Nanotubes Hybrids for Dual siPLK1 and Doxorubicin Delivery In Vitro.

Pereira S, Lee J, Rubio N, Hassan HA, Suffian IB, Wang JT, Klippstein R, Ballesteros B, Al-Jamal WT, Al-Jamal KT.

Pharm Res. 2015 Oct;32(10):3293-308. doi: 10.1007/s11095-015-1707-1. Epub 2015 Jun 18.


Multiphoton luminescence imaging of chemically functionalized multi-walled carbon nanotubes in cells and solid tumors.

Rubio N, Hirvonen LM, Chong EZ, Wang JT, Bourgognon M, Kafa H, Hassan HA, Al-Jamal WT, McCarthy D, Hogstrand C, Festy F, Al-Jamal KT.

Chem Commun (Camb). 2015 Jun 7;51(45):9366-9. doi: 10.1039/c5cc02675j.


The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo.

Kafa H, Wang JT, Rubio N, Venner K, Anderson G, Pach E, Ballesteros B, Preston JE, Abbott NJ, Al-Jamal KT.

Biomaterials. 2015;53:437-52. doi: 10.1016/j.biomaterials.2015.02.083. Epub 2015 Mar 19.


Correction to "Production of water-soluble few-layer graphene mesosheets by dry milling with hydrophobic drug".

Rubio N, Serra-Maia R, Kafa H, Mei KC, Pach E, Luckhurst W, Zloh M, Festy F, Richardson JP, Naglik JR, Ballesteros B, Al-Jamal KT.

Langmuir. 2015 Feb 24;31(7):2249. doi: 10.1021/acs.langmuir.5b00033. Epub 2015 Feb 6. No abstract available.


Evaluation of posterolateral lumbar fusion in sheep using mineral scaffolds seeded with cultured bone marrow cells.

Cuenca-López MD, Andrades JA, Gómez S, Zamora-Navas P, Guerado E, Rubio N, Blanco J, Becerra J.

Int J Mol Sci. 2014 Dec 16;15(12):23359-76. doi: 10.3390/ijms151223359.


Production of water-soluble few-layer graphene mesosheets by dry milling with hydrophobic drug.

Rubio N, Serra-Maia R, Kafa H, Mei KC, Pach E, Luckhurst W, Zloh M, Festy F, Richardson JP, Naglik JR, Ballesteros B, Al-Jamal KT.

Langmuir. 2014 Dec 16;30(49):14999-5008. doi: 10.1021/la5038475. Epub 2014 Dec 1. Erratum in: Langmuir. 2015 Feb 24;31(7):2249.


Possibilities for discrimination between chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios.

Rubio NC, Hastedt M, Gonzalez J, Pragst F.

Int J Legal Med. 2015 Jan;129(1):69-84. doi: 10.1007/s00414-014-1061-6. Epub 2014 Aug 20.


Theiler's virus infection provokes the overexpression of genes coding for the chemokine Ip10 (CXCL10) in SJL/J murine astrocytes, which can be inhibited by modulators of estrogen receptors.

Rubio N, Arevalo MA, Cerciat M, Sanz-Rodriguez F, Unkila M, Garcia-Segura LM.

J Neurovirol. 2014 Oct;20(5):485-95. doi: 10.1007/s13365-014-0273-3. Epub 2014 Jul 23.


Fast-proliferating adipose tissue mesenchymal-stromal-like cells for therapy.

Aguilar E, Bagó JR, Soler-Botija C, Alieva M, Rigola MA, Fuster C, Vila OF, Rubio N, Blanco J.

Stem Cells Dev. 2014 Dec 1;23(23):2908-20. doi: 10.1089/scd.2014.0231. Epub 2014 Aug 13.


Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors.

Vila OF, Martino MM, Nebuloni L, Kuhn G, Pérez-Amodio S, Müller R, Hubbell JA, Rubio N, Blanco J.

Acta Biomater. 2014 Oct;10(10):4377-89. doi: 10.1016/j.actbio.2014.05.028. Epub 2014 Jun 4.


Selection and characterization of a Patagonian Pichia kudriavzevii for wine deacidification.

Del Mónaco SM, Barda NB, Rubio NC, Caballero AC.

J Appl Microbiol. 2014 Aug;117(2):451-64. doi: 10.1111/jam.12547. Epub 2014 Jun 11.


Application of hygrine and cuscohygrine as possible markers to distinguish coca chewing from cocaine abuse on WDT and forensic cases.

Rubio NC, Strano-Rossi S, Tabernero MJ, Gonzalez JL, Anzillotti L, Chiarotti M, Bermejo AM.

Forensic Sci Int. 2014 Oct;243:30-4. doi: 10.1016/j.forsciint.2014.02.024. Epub 2014 Mar 6.


Polyethylene glycol conjugated polymeric nanocapsules for targeted delivery of quercetin to folate-expressing cancer cells in vitro and in vivo.

El-Gogary RI, Rubio N, Wang JT, Al-Jamal WT, Bourgognon M, Kafa H, Naeem M, Klippstein R, Abbate V, Leroux F, Bals S, Van Tendeloo G, Kamel AO, Awad GA, Mortada ND, Al-Jamal KT.

ACS Nano. 2014 Feb 25;8(2):1384-401. doi: 10.1021/nn405155b. Epub 2014 Jan 23.


p38(MAPK)-regulated induction of p62 and NBR1 after photodynamic therapy promotes autophagic clearance of ubiquitin aggregates and reduces reactive oxygen species levels by supporting Nrf2-antioxidant signaling.

Rubio N, Verrax J, Dewaele M, Verfaillie T, Johansen T, Piette J, Agostinis P.

Free Radic Biol Med. 2014 Feb;67:292-303. doi: 10.1016/j.freeradbiomed.2013.11.010. Epub 2013 Nov 22.


Bioluminescence imaging of cardiomyogenic and vascular differentiation of cardiac and subcutaneous adipose tissue-derived progenitor cells in fibrin patches in a myocardium infarct model.

Bagó JR, Soler-Botija C, Casaní L, Aguilar E, Alieva M, Rubio N, Bayes-Genis A, Blanco J.

Int J Cardiol. 2013 Nov 15;169(4):288-95. doi: 10.1016/j.ijcard.2013.09.013. Epub 2013 Oct 6.


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