Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 64

1.

The KDEL Receptor has a role in the Biogenesis and Trafficking of the Epithelial Sodium Channel (ENaC).

Bikard Y, Viviano J, Orr MN, Brown L, Brecker M, Jeger JL, Grits D, Suaud L, Rubenstein RC.

J Biol Chem. 2019 Oct 25. pii: jbc.RA119.008331. doi: 10.1074/jbc.RA119.008331. [Epub ahead of print]

2.

The presence of Aspergillus fumigatus is associated with worse respiratory quality of life in cystic fibrosis.

Hong G, Alby K, Ng SCW, Fleck V, Kubrak C, Rubenstein RC, Dorgan DJ, Kawut SM, Hadjiliadis D.

J Cyst Fibros. 2019 Aug 21. pii: S1569-1993(19)30840-9. doi: 10.1016/j.jcf.2019.08.008. [Epub ahead of print]

PMID:
31446018
3.

Dysregulated insulin in pancreatic insufficient cystic fibrosis with post-prandial hypoglycemia.

Kilberg MJ, Sheikh S, Stefanovski D, Kubrak C, De Leon DD, Hadjiliadis D, Rubenstein RC, Rickels MR, Kelly A.

J Cyst Fibros. 2019 Aug 8. pii: S1569-1993(19)30827-6. doi: 10.1016/j.jcf.2019.07.006. [Epub ahead of print]

PMID:
31402215
4.

Safety and efficacy of treatment with lumacaftor in combination with ivacaftor in younger patients with cystic fibrosis.

Cheng PC, Alexiou S, Rubenstein RC.

Expert Rev Respir Med. 2019 May;13(5):417-423. doi: 10.1080/17476348.2019.1602040. Epub 2019 Apr 8.

PMID:
30929526
5.

Islet Hormone and Incretin Secretion in Cystic Fibrosis after Four Months of Ivacaftor Therapy.

Kelly A, De Leon DD, Sheikh S, Camburn D, Kubrak C, Peleckis AJ, Stefanovski D, Hadjiliadis D, Rickels MR, Rubenstein RC.

Am J Respir Crit Care Med. 2019 Feb 1;199(3):342-351. doi: 10.1164/rccm.201806-1018OC.

PMID:
30130412
6.

β-Cell secretory defects are present in pancreatic insufficient cystic fibrosis with 1-hour oral glucose tolerance test glucose ≥155 mg/dL.

Nyirjesy SC, Sheikh S, Hadjiliadis D, De Leon DD, Peleckis AJ, Eiel JN, Kubrak C, Stefanovski D, Rubenstein RC, Rickels MR, Kelly A.

Pediatr Diabetes. 2018 Nov;19(7):1173-1182. doi: 10.1111/pedi.12700. Epub 2018 Jun 21.

7.

Editorial Focus: CFTR-dependent bicarbonate secretion by Calu-3 cells.

Rubenstein RC.

Physiol Rep. 2018 May;6(10):e13691. doi: 10.14814/phy2.13691. No abstract available.

8.

Sexual and reproductive health care utilization and preferences reported by young women with cystic fibrosis.

Kazmerski TM, Sawicki GS, Miller E, Jones KA, Abebe KZ, Tuchman LK, Ladores S, Rubenstein RC, Sagel SD, Weiner DJ, Pilewski JM, Orenstein DM, Borrero S.

J Cyst Fibros. 2018 Jan;17(1):64-70. doi: 10.1016/j.jcf.2017.08.009. Epub 2017 Sep 1.

PMID:
28866451
9.

Sexual and reproductive health behaviors and experiences reported by young women with cystic fibrosis.

Kazmerski TM, Sawicki GS, Miller E, Jones KA, Abebe KZ, Tuchman LK, Ladores S, Rubenstein RC, Sagel SD, Weiner DJ, Pilewski JM, Orenstein DM, Borrero S.

J Cyst Fibros. 2018 Jan;17(1):57-63. doi: 10.1016/j.jcf.2017.07.017. Epub 2017 Aug 1.

PMID:
28774749
10.

Reduced β-Cell Secretory Capacity in Pancreatic-Insufficient, but Not Pancreatic-Sufficient, Cystic Fibrosis Despite Normal Glucose Tolerance.

Sheikh S, Gudipaty L, De Leon DD, Hadjiliadis D, Kubrak C, Rosenfeld NK, Nyirjesy SC, Peleckis AJ, Malik S, Stefanovski D, Cuchel M, Rubenstein RC, Kelly A, Rickels MR.

Diabetes. 2017 Jan;66(1):134-144. doi: 10.2337/db16-0394. Epub 2016 Aug 5.

11.

Elevation of one hour plasma glucose during oral glucose tolerance testing.

Sheikh S, Putt ME, Forde KA, Rubenstein RC, Kelly A.

Pediatr Pulmonol. 2015 Oct;50(10):963-9. doi: 10.1002/ppul.23237. Epub 2015 Jun 18.

PMID:
26087115
12.

Efficacy and safety of ivacaftor in patients with cystic fibrosis who have an Arg117His-CFTR mutation: a double-blind, randomised controlled trial.

Moss RB, Flume PA, Elborn JS, Cooke J, Rowe SM, McColley SA, Rubenstein RC, Higgins M; VX11-770-110 (KONDUCT) Study Group.

Lancet Respir Med. 2015 Jul;3(7):524-33. doi: 10.1016/S2213-2600(15)00201-5. Epub 2015 Jun 9.

13.

Long-term treatment with oral N-acetylcysteine: affects lung function but not sputum inflammation in cystic fibrosis subjects. A phase II randomized placebo-controlled trial.

Conrad C, Lymp J, Thompson V, Dunn C, Davies Z, Chatfield B, Nichols D, Clancy J, Vender R, Egan ME, Quittell L, Michelson P, Antony V, Spahr J, Rubenstein RC, Moss RB, Herzenberg LA, Goss CH, Tirouvanziam R.

J Cyst Fibros. 2015 Mar;14(2):219-27. doi: 10.1016/j.jcf.2014.08.008. Epub 2014 Sep 13.

14.

IL-17A induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells.

Adams KM, Abraham V, Spielman D, Kolls JK, Rubenstein RC, Conner GE, Cohen NA, Kreindler JL.

PLoS One. 2014 Aug 20;9(8):e103263. doi: 10.1371/journal.pone.0103263. eCollection 2014.

15.

Patient and parent perceptions of the diagnosis and management of cystic fibrosis-related diabetes.

Millington K, Miller V, Rubenstein RC, Kelly A.

J Clin Transl Endocrinol. 2014 Jul 11;1(3):100-107. doi: 10.1016/j.jcte.2014.07.003. eCollection 2014 Sep.

16.

ERp29 regulates epithelial sodium channel functional expression by promoting channel cleavage.

Grumbach Y, Bikard Y, Suaud L, Chanoux RA, Rubenstein RC.

Am J Physiol Cell Physiol. 2014 Oct 15;307(8):C701-9. doi: 10.1152/ajpcell.00134.2014.

17.

Body composition and pulmonary function in cystic fibrosis.

Sheikh S, Zemel BS, Stallings VA, Rubenstein RC, Kelly A.

Front Pediatr. 2014 Apr 15;2:33. doi: 10.3389/fped.2014.00033. eCollection 2014.

18.

Seeing is believing: imaging early lung disease in cystic fibrosis.

Alexiou S, Rubenstein RC.

Am J Respir Crit Care Med. 2014 Apr 15;189(8):883-5. doi: 10.1164/rccm.201403-0422ED. No abstract available.

PMID:
24735030
19.

On preventing the extinction of the physician-scientist in pediatric pulmonology.

Rubenstein RC, Kreindler JL.

Front Pediatr. 2014 Jan 21;2:4. doi: 10.3389/fped.2014.00004. eCollection 2014. Review.

20.

Hsc70 negatively regulates epithelial sodium channel trafficking at multiple sites in epithelial cells.

Chanoux RA, Shubin CB, Robay A, Suaud L, Rubenstein RC.

Am J Physiol Cell Physiol. 2013 Oct 1;305(7):C776-87. doi: 10.1152/ajpcell.00059.2013. Epub 2013 Jul 24.

21.

Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection.

Clancy JP, Dupont L, Konstan MW, Billings J, Fustik S, Goss CH, Lymp J, Minic P, Quittner AL, Rubenstein RC, Young KR, Saiman L, Burns JL, Govan JR, Ramsey B, Gupta R; Arikace Study Group.

Thorax. 2013 Sep;68(9):818-25. doi: 10.1136/thoraxjnl-2012-202230. Epub 2013 Jun 8.

22.

Molecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic Fibrosis.

Chanoux RA, Rubenstein RC.

Front Pharmacol. 2012 Jul 17;3:137. doi: 10.3389/fphar.2012.00137. eCollection 2012.

23.

Multiple residues in the distal C terminus of the α-subunit have roles in modulating human epithelial sodium channel activity.

Mueller GM, Yan W, Copelovitch L, Jarman S, Wang Z, Kinlough CL, Tolino MA, Hughey RP, Kleyman TR, Rubenstein RC.

Am J Physiol Renal Physiol. 2012 Jul 15;303(2):F220-8. doi: 10.1152/ajprenal.00493.2011. Epub 2012 May 9.

24.

Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.

Liu J, Lu W, Guha S, Baltazar GC, Coffey EE, Laties AM, Rubenstein RC, Reenstra WW, Mitchell CH.

Am J Physiol Cell Physiol. 2012 Jul 15;303(2):C160-9. doi: 10.1152/ajpcell.00278.2011. Epub 2012 May 9.

25.

Hsp70 promotes epithelial sodium channel functional expression by increasing its association with coat complex II and its exit from endoplasmic reticulum.

Chanoux RA, Robay A, Shubin CB, Kebler C, Suaud L, Rubenstein RC.

J Biol Chem. 2012 Jun 1;287(23):19255-65. doi: 10.1074/jbc.M112.357756. Epub 2012 Apr 10.

26.

High prevalence of aquagenic wrinkling of the palms in patients with cystic fibrosis and association with measurable increases in transepidermal water loss.

Arkin LM, Flory JH, Shin DB, Gelfand JM, Treat JR, Allen J, Rubenstein RC, Yan AC.

Pediatr Dermatol. 2012 Sep-Oct;29(5):560-6. doi: 10.1111/j.1525-1470.2011.01708.x. Epub 2012 Apr 4.

PMID:
22471628
27.

Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report.

Ramsey BW, Banks-Schlegel S, Accurso FJ, Boucher RC, Cutting GR, Engelhardt JF, Guggino WB, Karp CL, Knowles MR, Kolls JK, LiPuma JJ, Lynch S, McCray PB Jr, Rubenstein RC, Singh PK, Sorscher E, Welsh M.

Am J Respir Crit Care Med. 2012 Apr 15;185(8):887-92. doi: 10.1164/rccm.201111-2068WS. Epub 2012 Feb 3.

28.

4-Phenylbutyrate stimulates Hsp70 expression through the Elp2 component of elongator and STAT-3 in cystic fibrosis epithelial cells.

Suaud L, Miller K, Panichelli AE, Randell RL, Marando CM, Rubenstein RC.

J Biol Chem. 2011 Dec 30;286(52):45083-92. doi: 10.1074/jbc.M111.293282. Epub 2011 Nov 8.

29.

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.

Clancy JP, Rowe SM, Accurso FJ, Aitken ML, Amin RS, Ashlock MA, Ballmann M, Boyle MP, Bronsveld I, Campbell PW, De Boeck K, Donaldson SH, Dorkin HL, Dunitz JM, Durie PR, Jain M, Leonard A, McCoy KS, Moss RB, Pilewski JM, Rosenbluth DB, Rubenstein RC, Schechter MS, Botfield M, Ordoñez CL, Spencer-Green GT, Vernillet L, Wisseh S, Yen K, Konstan MW.

Thorax. 2012 Jan;67(1):12-8. doi: 10.1136/thoraxjnl-2011-200393. Epub 2011 Aug 8.

30.

ERp29 regulates DeltaF508 and wild-type cystic fibrosis transmembrane conductance regulator (CFTR) trafficking to the plasma membrane in cystic fibrosis (CF) and non-CF epithelial cells.

Suaud L, Miller K, Alvey L, Yan W, Robay A, Kebler C, Kreindler JL, Guttentag S, Hubbard MJ, Rubenstein RC.

J Biol Chem. 2011 Jun 17;286(24):21239-53. doi: 10.1074/jbc.M111.240267. Epub 2011 Apr 27.

31.

Nocturnal saturation and glucose tolerance in children with cystic fibrosis.

Suratwala D, Chan JS, Kelly A, Meltzer LJ, Gallagher PR, Traylor J, Rubenstein RC, Marcus CL.

Thorax. 2011 Jul;66(7):574-8. doi: 10.1136/thx.2010.142141. Epub 2011 Jan 27.

PMID:
21273357
32.

Elevation of 1-hour plasma glucose during oral glucose tolerance testing is associated with worse pulmonary function in cystic fibrosis.

Brodsky J, Dougherty S, Makani R, Rubenstein RC, Kelly A.

Diabetes Care. 2011 Feb;34(2):292-5. doi: 10.2337/dc10-1604. Epub 2011 Jan 12.

33.

Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation.

Accurso FJ, Rowe SM, Clancy JP, Boyle MP, Dunitz JM, Durie PR, Sagel SD, Hornick DB, Konstan MW, Donaldson SH, Moss RB, Pilewski JM, Rubenstein RC, Uluer AZ, Aitken ML, Freedman SD, Rose LM, Mayer-Hamblett N, Dong Q, Zha J, Stone AJ, Olson ER, Ordoñez CL, Campbell PW, Ashlock MA, Ramsey BW.

N Engl J Med. 2010 Nov 18;363(21):1991-2003. doi: 10.1056/NEJMoa0909825.

34.

Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.

Rubenstein RC, Lockwood SR, Lide E, Bauer R, Suaud L, Grumbach Y.

Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L88-L101. doi: 10.1152/ajplung.00142.2010. Epub 2010 Oct 8.

35.

Carrier screening, incidence of cystic fibrosis, and difficult decisions.

Liou TG, Rubenstein RC.

JAMA. 2009 Dec 16;302(23):2595-6. doi: 10.1001/jama.2009.1865. No abstract available.

PMID:
20009063
36.

ERp29 restricts Connexin43 oligomerization in the endoplasmic reticulum.

Das S, Smith TD, Sarma JD, Ritzenthaler JD, Maza J, Kaplan BE, Cunningham LA, Suaud L, Hubbard MJ, Rubenstein RC, Koval M.

Mol Biol Cell. 2009 May;20(10):2593-604. doi: 10.1091/mbc.E08-07-0790. Epub 2009 Mar 25.

37.

Murine nasal septa for respiratory epithelial air-liquid interface cultures.

Antunes MB, Woodworth BA, Bhargave G, Xiong G, Aguilar JL, Ratner AJ, Kreindler JL, Rubenstein RC, Cohen NA.

Biotechniques. 2007 Aug;43(2):195-6, 198, 200 passim.

38.

Small heat shock protein alphaA-crystallin regulates epithelial sodium channel expression.

Kashlan OB, Mueller GM, Qamar MZ, Poland PA, Ahner A, Rubenstein RC, Hughey RP, Brodsky JL, Kleyman TR.

J Biol Chem. 2007 Sep 21;282(38):28149-56. Epub 2007 Jul 30.

39.

Intracellular trafficking of a polymorphism in the COOH terminus of the alpha-subunit of the human epithelial sodium channel is modulated by casein kinase 1.

Yan W, Spruce L, Rosenblatt MM, Kleyman TR, Rubenstein RC.

Am J Physiol Renal Physiol. 2007 Sep;293(3):F868-76. Epub 2007 Jun 27.

40.

Regulatory interactions of N1303K-CFTR and ENaC in Xenopus oocytes: evidence that chloride transport is not necessary for inhibition of ENaC.

Suaud L, Yan W, Carattino MD, Robay A, Kleyman TR, Rubenstein RC.

Am J Physiol Cell Physiol. 2007 Apr;292(4):C1553-61. Epub 2006 Dec 20.

42.

Abnormal regulatory interactions of I148T-CFTR and the epithelial Na+ channel in Xenopus oocytes.

Suaud L, Yan W, Rubenstein RC.

Am J Physiol Cell Physiol. 2007 Jan;292(1):C603-11. Epub 2006 Jul 5.

43.

Cystic fibrosis as a risk factor for recurrent venous thrombosis at a pediatric tertiary care hospital.

Raffini LJ, Raybagkar D, Blumenstein MS, Rubenstein RC, Manno CS.

J Pediatr. 2006 May;148(5):659-64.

PMID:
16737881
44.

Differential effects of Hsc70 and Hsp70 on the intracellular trafficking and functional expression of epithelial sodium channels.

Goldfarb SB, Kashlan OB, Watkins JN, Suaud L, Yan W, Kleyman TR, Rubenstein RC.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5817-22. Epub 2006 Apr 3.

45.

Risk factors for death of patients with cystic fibrosis awaiting lung transplantation.

Belkin RA, Henig NR, Singer LG, Chaparro C, Rubenstein RC, Xie SX, Yee JY, Kotloff RM, Lipson DA, Bunin GR.

Am J Respir Crit Care Med. 2006 Mar 15;173(6):659-66. Epub 2005 Dec 30.

46.

Differential modulation of a polymorphism in the COOH terminus of the alpha-subunit of the human epithelial sodium channel by protein kinase Cdelta.

Yan W, Suaud L, Kleyman TR, Rubenstein RC.

Am J Physiol Renal Physiol. 2006 Feb;290(2):F279-88. Epub 2005 Sep 20.

47.

Novel, mechanism-based therapies for cystic fibrosis.

Rubenstein RC.

Curr Opin Pediatr. 2005 Jun;17(3):385-92. Review.

PMID:
15891431
48.

Functional polymorphism in the carboxyl terminus of the alpha-subunit of the human epithelial sodium channel.

Samaha FF, Rubenstein RC, Yan W, Ramkumar M, Levy DI, Ahn YJ, Sheng S, Kleyman TR.

J Biol Chem. 2004 Jun 4;279(23):23900-7. Epub 2004 Apr 6.

49.

Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes.

Yan W, Samaha FF, Ramkumar M, Kleyman TR, Rubenstein RC.

J Biol Chem. 2004 May 28;279(22):23183-92. Epub 2004 Mar 26.

50.

Supplemental Content

Loading ...
Support Center