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Items: 1 to 50 of 366

1.

Immature excitatory neurons develop during adolescence in the human amygdala.

Sorrells SF, Paredes MF, Velmeshev D, Herranz-Pérez V, Sandoval K, Mayer S, Chang EF, Insausti R, Kriegstein AR, Rubenstein JL, Manuel Garcia-Verdugo J, Huang EJ, Alvarez-Buylla A.

Nat Commun. 2019 Jun 21;10(1):2748. doi: 10.1038/s41467-019-10765-1.

PMID:
31227709
2.

Evolving Treatments for Primary Central Nervous System Lymphoma.

Ferreri AJM, Holdhoff M, Nayak L, Rubenstein JL.

Am Soc Clin Oncol Educ Book. 2019 Jan;39:454-466. doi: 10.1200/EDBK_242547. Epub 2019 May 17.

PMID:
31099614
3.

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders.

Sohal VS, Rubenstein JLR.

Mol Psychiatry. 2019 May 14. doi: 10.1038/s41380-019-0426-0. [Epub ahead of print] Review.

PMID:
31089192
4.

Maintenance Lenalidomide in Primary CNS Lymphoma.

Rubenstein JL, Geng H, Vu K, Mannis G, Formaker P, Hwang J, Munster PN, Damato B.

Ann Oncol. 2019 May 2. pii: mdz142. doi: 10.1093/annonc/mdz142. [Epub ahead of print] No abstract available.

PMID:
31046114
5.

Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer.

Forés-Martos J, Catalá-López F, Sánchez-Valle J, Ibáñez K, Tejero H, Palma-Gudiel H, Climent J, Pancaldi V, Fañanás L, Arango C, Parellada M, Baudot A, Vogt D, Rubenstein JL, Valencia A, Tabarés-Seisdedos R.

Mol Autism. 2019 Apr 8;10:17. doi: 10.1186/s13229-019-0262-8. eCollection 2019.

6.

Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.

Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z.

Cereb Cortex. 2019 Feb 23. pii: bhz018. doi: 10.1093/cercor/bhz018. [Epub ahead of print]

PMID:
30796806
7.

Low-dose lenalidomide maintenance after induction therapy in older patients with primary central nervous system lymphoma.

Vu K, Mannis G, Hwang J, Geng H, Rubenstein JL.

Br J Haematol. 2019 Jul;186(1):180-183. doi: 10.1111/bjh.15787. Epub 2019 Feb 3. No abstract available.

PMID:
30714128
8.

Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function.

Pai EL, Vogt D, Clemente-Perez A, McKinsey GL, Cho FS, Hu JS, Wimer M, Paul A, Fazel Darbandi S, Pla R, Nowakowski TJ, Goodrich LV, Paz JT, Rubenstein JLR.

Cell Rep. 2019 Jan 29;26(5):1157-1173.e5. doi: 10.1016/j.celrep.2019.01.031.

9.

Insights from a Case of Vitreoretinal Lymphoma.

Damato BE, Bever GJ, Afshar AR, Rubenstein JL.

Ocul Oncol Pathol. 2019 Jan;5(1):13-19. doi: 10.1159/000487949. Epub 2018 Apr 17.

10.

Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder.

An JY, Lin K, Zhu L, Werling DM, Dong S, Brand H, Wang HZ, Zhao X, Schwartz GB, Collins RL, Currall BB, Dastmalchi C, Dea J, Duhn C, Gilson MC, Klei L, Liang L, Markenscoff-Papadimitriou E, Pochareddy S, Ahituv N, Buxbaum JD, Coon H, Daly MJ, Kim YS, Marth GT, Neale BM, Quinlan AR, Rubenstein JL, Sestan N, State MW, Willsey AJ, Talkowski ME, Devlin B, Roeder K, Sanders SJ.

Science. 2018 Dec 14;362(6420). pii: eaat6576. doi: 10.1126/science.aat6576.

11.

Comprehensive approach to diagnosis and treatment of newly diagnosed primary CNS lymphoma.

Grommes C, Rubenstein JL, DeAngelis LM, Ferreri AJM, Batchelor TT.

Neuro Oncol. 2019 Feb 19;21(3):296-305. doi: 10.1093/neuonc/noy192.

PMID:
30418592
12.

Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity.

Fazel Darbandi S, Robinson Schwartz SE, Qi Q, Catta-Preta R, Pai EL, Mandell JD, Everitt A, Rubin A, Krasnoff RA, Katzman S, Tastad D, Nord AS, Willsey AJ, Chen B, State MW, Sohal VS, Rubenstein JLR.

Neuron. 2018 Nov 21;100(4):831-845.e7. doi: 10.1016/j.neuron.2018.09.027. Epub 2018 Oct 11.

PMID:
30318412
13.

Genomic analysis of transcriptional networks directing progression of cell states during MGE development.

Sandberg M, Taher L, Hu J, Black BL, Nord AS, Rubenstein JLR.

Neural Dev. 2018 Sep 14;13(1):21. doi: 10.1186/s13064-018-0119-4.

14.

Can rituximab unlock the innate potential of checkpoint blockade in the CNS?

Rubenstein JL.

Leuk Lymphoma. 2019 Feb;60(2):281-283. doi: 10.1080/10428194.2018.1510496. Epub 2018 Sep 6. No abstract available.

PMID:
30188237
15.

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner S, Rubenstein JLR, Hevner RF.

Front Neurosci. 2018 Aug 22;12:571. doi: 10.3389/fnins.2018.00571. eCollection 2018.

16.

Phase 1 investigation of lenalidomide/rituximab plus outcomes of lenalidomide maintenance in relapsed CNS lymphoma.

Rubenstein JL, Geng H, Fraser EJ, Formaker P, Chen L, Sharma J, Killea P, Choi K, Ventura J, Kurhanewicz J, Lowell C, Hwang J, Treseler P, Sneed PK, Li J, Wang X, Chen N, Gangoiti J, Munster PN, Damato B.

Blood Adv. 2018 Jul 10;2(13):1595-1607. doi: 10.1182/bloodadvances.2017014845.

17.

SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression.

Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z.

Development. 2018 Jul 23;145(14). pii: dev165456. doi: 10.1242/dev.165456.

18.

Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development.

Liu Z, Zhang Z, Lindtner S, Li Z, Xu Z, Wei S, Liang Q, Wen Y, Tao G, You Y, Chen B, Wang Y, Rubenstein JL, Yang Z.

Cereb Cortex. 2019 Jun 1;29(6):2653-2667. doi: 10.1093/cercor/bhy133.

PMID:
29878134
19.

An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder.

Werling DM, Brand H, An JY, Stone MR, Zhu L, Glessner JT, Collins RL, Dong S, Layer RM, Markenscoff-Papadimitriou E, Farrell A, Schwartz GB, Wang HZ, Currall BB, Zhao X, Dea J, Duhn C, Erdman CA, Gilson MC, Yadav R, Handsaker RE, Kashin S, Klei L, Mandell JD, Nowakowski TJ, Liu Y, Pochareddy S, Smith L, Walker MF, Waterman MJ, He X, Kriegstein AR, Rubenstein JL, Sestan N, McCarroll SA, Neale BM, Coon H, Willsey AJ, Buxbaum JD, Daly MJ, State MW, Quinlan AR, Marth GT, Roeder K, Devlin B, Talkowski ME, Sanders SJ.

Nat Genet. 2018 Apr 26;50(5):727-736. doi: 10.1038/s41588-018-0107-y.

20.

Tbr1 instructs laminar patterning of retinal ganglion cell dendrites.

Liu J, Reggiani JDS, Laboulaye MA, Pandey S, Chen B, Rubenstein JLR, Krishnaswamy A, Sanes JR.

Nat Neurosci. 2018 May;21(5):659-670. doi: 10.1038/s41593-018-0127-z. Epub 2018 Apr 9.

21.

Ultraconserved Enhancers Are Required for Normal Development.

Dickel DE, Ypsilanti AR, Pla R, Zhu Y, Barozzi I, Mannion BJ, Khin YS, Fukuda-Yuzawa Y, Plajzer-Frick I, Pickle CS, Lee EA, Harrington AN, Pham QT, Garvin TH, Kato M, Osterwalder M, Akiyama JA, Afzal V, Rubenstein JLR, Pennacchio LA, Visel A.

Cell. 2018 Jan 25;172(3):491-499.e15. doi: 10.1016/j.cell.2017.12.017. Epub 2018 Jan 18.

22.

Biology of CNS lymphoma and the potential of novel agents.

Rubenstein JL.

Hematology Am Soc Hematol Educ Program. 2017 Dec 8;2017(1):556-564. doi: 10.1182/asheducation-2017.1.556. Review.

23.

THERAPEUTIC VITRECTOMY AS AN ADJUNCT TREATMENT TO SYSTEMIC CHEMOTHERAPY FOR INTRAOCULAR LYMPHOMA.

Bever GJ, Kim DJ, Afshar AR, Rubenstein JL, Damato BE.

Retin Cases Brief Rep. 2017 Nov 23. doi: 10.1097/ICB.0000000000000668. [Epub ahead of print]

24.

Cortical interneuron development: a tale of time and space.

Hu JS, Vogt D, Sandberg M, Rubenstein JL.

Development. 2017 Nov 1;144(21):3867-3878. doi: 10.1242/dev.132852. Review.

25.

Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis.

Pla R, Stanco A, Howard MA, Rubin AN, Vogt D, Mortimer N, Cobos I, Potter GB, Lindtner S, Price JD, Nord AS, Visel A, Schreiner CE, Baraban SC, Rowitch DH, Rubenstein JLR.

Cereb Cortex. 2018 Nov 1;28(11):3797-3815. doi: 10.1093/cercor/bhx241.

PMID:
29028947
26.

Mouse Cntnap2 and Human CNTNAP2 ASD Alleles Cell Autonomously Regulate PV+ Cortical Interneurons.

Vogt D, Cho KKA, Shelton SM, Paul A, Huang ZJ, Sohal VS, Rubenstein JLR.

Cereb Cortex. 2018 Nov 1;28(11):3868-3879. doi: 10.1093/cercor/bhx248.

PMID:
29028946
27.

Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development.

Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z.

Cereb Cortex. 2018 Sep 1;28(9):3278-3294. doi: 10.1093/cercor/bhx199.

PMID:
28981617
28.

GABAergic Interneuron Differentiation in the Basal Forebrain Is Mediated through Direct Regulation of Glutamic Acid Decarboxylase Isoforms by Dlx Homeobox Transcription Factors.

Le TN, Zhou QP, Cobos I, Zhang S, Zagozewski J, Japoni S, Vriend J, Parkinson T, Du G, Rubenstein JL, Eisenstat DD.

J Neurosci. 2017 Sep 6;37(36):8816-8829. doi: 10.1523/JNEUROSCI.2125-16.2017. Epub 2017 Aug 8.

29.

Coup-TF1 and Coup-TF2 control subtype and laminar identity of MGE-derived neocortical interneurons.

Hu JS, Vogt D, Lindtner S, Sandberg M, Silberberg SN, Rubenstein JLR.

Development. 2017 Aug 1;144(15):2837-2851. doi: 10.1242/dev.150664. Epub 2017 Jul 10.

30.

Generation of pure GABAergic neurons by transcription factor programming.

Yang N, Chanda S, Marro S, Ng YH, Janas JA, Haag D, Ang CE, Tang Y, Flores Q, Mall M, Wapinski O, Li M, Ahlenius H, Rubenstein JL, Chang HY, Buylla AA, Südhof TC, Wernig M.

Nat Methods. 2017 Jun;14(6):621-628. doi: 10.1038/nmeth.4291. Epub 2017 May 15.

31.

Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity.

Raju CS, Spatazza J, Stanco A, Larimer P, Sorrells SF, Kelley KW, Nicholas CR, Paredes MF, Lui JH, Hasenstaub AR, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL, Oldham MC.

Cereb Cortex. 2018 Jun 1;28(6):1946-1958. doi: 10.1093/cercor/bhx101.

32.

Regression of methotrexate-resistant AIDS-related primary central nervous system lymphoma with lenalidomide plus combination anti-retroviral therapy.

Gupta NK, Wang CC, Mannis GN, Yu JJ, Rubenstein JL.

Leuk Lymphoma. 2017 Nov;58(11):2748-2751. doi: 10.1080/10428194.2017.1312374. Epub 2017 Apr 10. No abstract available.

33.

Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types.

Chen YJ, Friedman BA, Ha C, Durinck S, Liu J, Rubenstein JL, Seshagiri S, Modrusan Z.

Sci Rep. 2017 Mar 31;7:45656. doi: 10.1038/srep45656.

34.

Functional consequences of I56ii Dlx enhancer deletion in the developing mouse forebrain.

Fazel Darbandi S, Poitras L, Monis S, Lindtner S, Yu M, Hatch G, Rubenstein JL, Ekker M.

Dev Biol. 2016 Oct 27. pii: S0012-1606(16)30263-9. doi: 10.1016/j.ydbio.2016.10.015. [Epub ahead of print]

35.

The Challenge of Primary Central Nervous System Lymphoma.

Carnevale J, Rubenstein JL.

Hematol Oncol Clin North Am. 2016 Dec;30(6):1293-1316. doi: 10.1016/j.hoc.2016.07.013. Review.

36.

Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum.

Gobius I, Morcom L, Suárez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ.

Cell Rep. 2016 Oct 11;17(3):735-747. doi: 10.1016/j.celrep.2016.09.033.

37.

Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate.

Silberberg SN, Taher L, Lindtner S, Sandberg M, Nord AS, Vogt D, Mckinsey GL, Hoch R, Pattabiraman K, Zhang D, Ferran JL, Rajkovic A, Golonzhka O, Kim C, Zeng H, Puelles L, Visel A, Rubenstein JLR.

Neuron. 2016 Oct 5;92(1):59-74. doi: 10.1016/j.neuron.2016.09.027.

38.

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.

Sandberg M, Flandin P, Silberberg S, Su-Feher L, Price JD, Hu JS, Kim C, Visel A, Nord AS, Rubenstein JLR.

Neuron. 2016 Sep 21;91(6):1260-1275. doi: 10.1016/j.neuron.2016.08.020.

39.

Long-term survival in AIDS-related primary central nervous system lymphoma.

Gupta NK, Nolan A, Omuro A, Reid EG, Wang CC, Mannis G, Jaglal M, Chavez JC, Rubinstein PG, Griffin A, Abrams DI, Hwang J, Kaplan LD, Luce JA, Volberding P, Treseler PA, Rubenstein JL.

Neuro Oncol. 2017 Jan;19(1):99-108. doi: 10.1093/neuonc/now155. Epub 2016 Aug 30.

40.

The Cytokine CXCL12 Promotes Basket Interneuron Inhibitory Synapses in the Medial Prefrontal Cortex.

Wu PR, Cho KKA, Vogt D, Sohal VS, Rubenstein JLR.

Cereb Cortex. 2017 Sep 1;27(9):4303-4313. doi: 10.1093/cercor/bhw230.

41.

A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients.

Sun Y, Paşca SP, Portmann T, Goold C, Worringer KA, Guan W, Chan KC, Gai H, Vogt D, Chen YJ, Mao R, Chan K, Rubenstein JL, Madison DV, Hallmayer J, Froehlich-Santino WM, Bernstein JA, Dolmetsch RE.

Elife. 2016 Jul 26;5. pii: e13073. doi: 10.7554/eLife.13073.

42.

The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons.

Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z.

Cell Rep. 2016 Aug 2;16(5):1431-1444. doi: 10.1016/j.celrep.2016.06.090. Epub 2016 Jul 21.

43.

TBR1 regulates autism risk genes in the developing neocortex.

Notwell JH, Heavner WE, Darbandi SF, Katzman S, McKenna WL, Ortiz-Londono CF, Tastad D, Eckler MJ, Rubenstein JL, McConnell SK, Chen B, Bejerano G.

Genome Res. 2016 Aug;26(8):1013-22. doi: 10.1101/gr.203612.115. Epub 2016 Jun 20.

44.

Radial derivatives of the mouse ventral pallium traced with Dbx1-LacZ reporters.

Puelles L, Medina L, Borello U, Legaz I, Teissier A, Pierani A, Rubenstein JL.

J Chem Neuroanat. 2016 Sep;75(Pt A):2-19. doi: 10.1016/j.jchemneu.2015.10.011. Epub 2015 Dec 31.

PMID:
26748312
45.

Accelerated Evolution of Enhancer Hotspots in the Mammal Ancestor.

Holloway AK, Bruneau BG, Sukonnik T, Rubenstein JL, Pollard KS.

Mol Biol Evol. 2016 Apr;33(4):1008-18. doi: 10.1093/molbev/msv344. Epub 2015 Dec 29.

46.

Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis.

Prochazka J, Prochazkova M, Du W, Spoutil F, Tureckova J, Hoch R, Shimogori T, Sedlacek R, Rubenstein JL, Wittmann T, Klein OD.

Dev Cell. 2015 Dec 21;35(6):713-24. doi: 10.1016/j.devcel.2015.11.025.

47.

Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.

Golonzhka O, Nord A, Tang PLF, Lindtner S, Ypsilanti AR, Ferretti E, Visel A, Selleri L, Rubenstein JLR.

Neuron. 2015 Dec 16;88(6):1192-1207. doi: 10.1016/j.neuron.2015.10.045. Epub 2015 Dec 6.

48.

EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex.

Lim JW, Donahoo AL, Bunt J, Edwards TJ, Fenlon LR, Liu Y, Zhou J, Moldrich RX, Piper M, Gobius I, Bailey TL, Wray NR, Kessaris N, Poo MM, Rubenstein JL, Richards LJ.

Development. 2015 Nov 1;142(21):3746-57. doi: 10.1242/dev.119909.

49.

Performance of Apparent Diffusion Coefficient Values and Conventional MRI Features in Differentiating Tumefactive Demyelinating Lesions From Primary Brain Neoplasms.

Mabray MC, Cohen BA, Villanueva-Meyer JE, Valles FE, Barajas RF, Rubenstein JL, Cha S.

AJR Am J Roentgenol. 2015 Nov;205(5):1075-85. doi: 10.2214/AJR.14.13970.

50.

Prolonged Complete Response in a Pediatric Patient With Primary Peripheral T-Cell Lymphoma of the Central Nervous System.

Shalabi H, Angiolillo A, Vezina G, Rubenstein JL, Pittaluga S, Raffeld M, Marcus L.

Pediatr Hematol Oncol. 2015;32(8):529-34. doi: 10.3109/08880018.2015.1074325. Epub 2015 Sep 18.

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