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Items: 1 to 50 of 61

1.

Blood-based lung cancer biomarkers identified through proteomic discovery in cancer tissues, cell lines and conditioned medium.

Birse CE, Lagier RJ, FitzHugh W, Pass HI, Rom WN, Edell ES, Bungum AO, Maldonado F, Jett JR, Mesri M, Sult E, Joseloff E, Li A, Heidbrink J, Dhariwal G, Danis C, Tomic JL, Bruce RJ, Moore PA, He T, Lewis ME, Ruben SM.

Clin Proteomics. 2015 Jul 16;12(1):18. doi: 10.1186/s12014-015-9090-9. eCollection 2015.

2.

RNA interference characterization of proteins discovered by proteomic analysis of pancreatic cancer reveals function in cell growth and survival.

Lee CN, Heidbrink JL, McKinnon K, Bushman V, Olsen H, FitzHugh W, Li A, Van Orden K, He T, Ruben SM, Moore PA.

Pancreas. 2012 Jan;41(1):84-94. doi: 10.1097/MPA.0b013e3182236385.

PMID:
21934552
3.

Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery.

Fang DD, Kim YJ, Lee CN, Aggarwal S, McKinnon K, Mesmer D, Norton J, Birse CE, He T, Ruben SM, Moore PA.

Br J Cancer. 2010 Apr 13;102(8):1265-75. doi: 10.1038/sj.bjc.6605610. Epub 2010 Mar 23.

4.

Immune modulator CD70 as a potential cisplatin resistance predictive marker in ovarian cancer.

Aggarwal S, He T, Fitzhugh W, Rosenthal K, Feild B, Heidbrink J, Mesmer D, Ruben SM, Moore PA.

Gynecol Oncol. 2009 Dec;115(3):430-7. doi: 10.1016/j.ygyno.2009.08.031. Epub 2009 Oct 2.

PMID:
19800108
5.

Reference map for liquid chromatography-mass spectrometry-based quantitative proteomics.

Kim YJ, Feild B, Fitzhugh W, Heidbrink JL, Duff JW, Heil J, Ruben SM, He T.

Anal Biochem. 2009 Oct 15;393(2):155-62. doi: 10.1016/j.ab.2009.06.015. Epub 2009 Jun 16.

PMID:
19538932
6.

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers.

Smith LM, Nesterova A, Ryan MC, Duniho S, Jonas M, Anderson M, Zabinski RF, Sutherland MK, Gerber HP, Van Orden KL, Moore PA, Ruben SM, Carter PJ.

Br J Cancer. 2008 Jul 8;99(1):100-9. doi: 10.1038/sj.bjc.6604437. Epub 2008 Jun 10.

7.

Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients.

Nicol GR, Han M, Kim J, Birse CE, Brand E, Nguyen A, Mesri M, FitzHugh W, Kaminker P, Moore PA, Ruben SM, He T.

Mol Cell Proteomics. 2008 Oct;7(10):1974-82. doi: 10.1074/mcp.M700476-MCP200. Epub 2008 Apr 3.

8.

Reproducibility assessment of relative quantitation strategies for LC-MS based proteomics.

Kim YJ, Zhan P, Feild B, Ruben SM, He T.

Anal Chem. 2007 Aug 1;79(15):5651-8. Epub 2007 Jun 20.

PMID:
17580949
9.

Drug target identification and quantitative proteomics.

He T, Jin Kim Y, Heidbrink JL, Moore PA, Ruben SM.

Expert Opin Drug Discov. 2006 Oct;1(5):477-89. doi: 10.1517/17460441.1.5.477.

PMID:
23495947
10.

LCN6, a novel human epididymal lipocalin.

Hamil KG, Liu Q, Sivashanmugam P, Anbalagan M, Yenugu S, Soundararajan R, Grossman G, Rao AJ, Birse CE, Ruben SM, Richardson RT, Zhang YL, O'Rand MG, Petrusz P, French FS, Hall SH.

Reprod Biol Endocrinol. 2003 Nov 14;1:112.

11.

The remarkable flexibility of the human antibody repertoire; isolation of over one thousand different antibodies to a single protein, BLyS.

Edwards BM, Barash SC, Main SH, Choi GH, Minter R, Ullrich S, Williams E, Du Fou L, Wilton J, Albert VR, Ruben SM, Vaughan TJ.

J Mol Biol. 2003 Nov 14;334(1):103-18.

PMID:
14596803
13.

An integrated functional genomics screening program reveals a role for BMP-9 in glucose homeostasis.

Chen C, Grzegorzewski KJ, Barash S, Zhao Q, Schneider H, Wang Q, Singh M, Pukac L, Bell AC, Duan R, Coleman T, Duttaroy A, Cheng S, Hirsch J, Zhang L, Lazard Y, Fischer C, Barber MC, Ma ZD, Zhang YQ, Reavey P, Zhong L, Teng B, Sanyal I, Ruben SM, Blondel O, Birse CE.

Nat Biotechnol. 2003 Mar;21(3):294-301. Epub 2003 Feb 24.

PMID:
12598908
14.

TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.

Migone TS, Zhang J, Luo X, Zhuang L, Chen C, Hu B, Hong JS, Perry JW, Chen SF, Zhou JX, Cho YH, Ullrich S, Kanakaraj P, Carrell J, Boyd E, Olsen HS, Hu G, Pukac L, Liu D, Ni J, Kim S, Gentz R, Feng P, Moore PA, Ruben SM, Wei P.

Immunity. 2002 Mar;16(3):479-92.

15.

Interferon-kappa, a novel type I interferon expressed in human keratinocytes.

LaFleur DW, Nardelli B, Tsareva T, Mather D, Feng P, Semenuk M, Taylor K, Buergin M, Chinchilla D, Roshke V, Chen G, Ruben SM, Pitha PM, Coleman TA, Moore PA.

J Biol Chem. 2001 Oct 26;276(43):39765-71. Epub 2001 Aug 20.

16.

Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis.

Richardson RT, Sivashanmugam P, Hall SH, Hamil KG, Moore PA, Ruben SM, French FS, O'Rand M.

Gene. 2001 May 30;270(1-2):93-102.

PMID:
11404006
17.

Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS.

Wu Y, Bressette D, Carrell JA, Kaufman T, Feng P, Taylor K, Gan Y, Cho YH, Garcia AD, Gollatz E, Dimke D, LaFleur D, Migone TS, Nardelli B, Wei P, Ruben SM, Ullrich SJ, Olsen HS, Kanakaraj P, Moore PA, Baker KP.

J Biol Chem. 2000 Nov 10;275(45):35478-85.

18.

A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity.

Shi Y, Ullrich SJ, Zhang J, Connolly K, Grzegorzewski KJ, Barber MC, Wang W, Wathen K, Hodge V, Fisher CL, Olsen H, Ruben SM, Knyazev I, Cho YH, Kao V, Wilkinson KA, Carrell JA, Ebner R.

J Biol Chem. 2000 Jun 23;275(25):19167-76.

19.

HE2beta and HE2gamma, new members of an epididymis-specific family of androgen-regulated proteins in the human.

Hamil KG, Sivashanmugam P, Richardson RT, Grossman G, Ruben SM, Mohler JL, Petrusz P, O'Rand MG, French FS, Hall SH.

Endocrinology. 2000 Mar;141(3):1245-53.

PMID:
10698202
20.

VEGI, a new member of the TNF family activates nuclear factor-kappa B and c-Jun N-terminal kinase and modulates cell growth.

Haridas V, Shrivastava A, Su J, Yu GL, Ni J, Liu D, Chen SF, Ni Y, Ruben SM, Gentz R, Aggarwal BB.

Oncogene. 1999 Nov 11;18(47):6496-504.

21.

Outcome predictors in pregnant opiate and polydrug users.

McCarthy JE, Siney C, Shaw NJ, Ruben SM.

Eur J Pediatr. 1999 Sep;158(9):748-9.

PMID:
10485309
22.

Effects of keratinocyte growth factor-2 (KGF-2) on wound healing in an ischaemia-impaired rabbit ear model and on scar formation.

Xia YP, Zhao Y, Marcus J, Jimenez PA, Ruben SM, Moore PA, Khan F, Mustoe TA.

J Pathol. 1999 Aug;188(4):431-8.

PMID:
10440755
23.

Use of genomic tools in the identification of bone-related therapeutics.

Ruben SM.

Bone. 1999 Jul;25(1):81-3. No abstract available.

PMID:
10423026
24.

BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.

Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, Soppet D, Charters M, Gentz R, Parmelee D, Li Y, Galperina O, Giri J, Roschke V, Nardelli B, Carrell J, Sosnovtseva S, Greenfield W, Ruben SM, Olsen HS, Fikes J, Hilbert DM.

Science. 1999 Jul 9;285(5425):260-3.

25.

TRAIL (Apo-2L) and TRAIL receptors in human placentas: implications for immune privilege.

Phillips TA, Ni J, Pan G, Ruben SM, Wei YF, Pace JL, Hunt JS.

J Immunol. 1999 May 15;162(10):6053-9.

26.

Identification and characterization of a novel member of the fibroblast growth factor family.

Greene JM, Li YL, Yourey PA, Gruber J, Carter KC, Shell BK, Dillon PA, Florence C, Duan DR, Blunt A, Ornitz DM, Ruben SM, Alderson RF.

Eur J Neurosci. 1998 May;10(5):1911-25.

PMID:
9751161
27.

Expression and reconstitution of NF-kappaB from insect cells using a baculovirus vector.

Coleman TA, Huddleston KA, Ruben SM, Rosen CA, Gentz R.

Protein Expr Purif. 1997 Feb;9(1):40-8.

PMID:
9116500
28.

Maintaining low HIV seroprevalence among injecting drug users.

Morrison CL, Ruben SM.

JAMA. 1996 Feb 28;275(8):596-8. No abstract available.

PMID:
8594238
29.

Zopiclone abuse among polydrug users.

Sikdar S, Ruben SM.

Addiction. 1996 Feb;91(2):285-6. No abstract available.

PMID:
8835284
30.

Can outreach work?

Morrison CL, Ruben SM.

Addiction. 1995 Oct;90(10):1401-4. No abstract available.

PMID:
8616469
31.

The development of healthcare services for drug misusers and prostitutes.

Morrison CL, Ruben SM.

Postgrad Med J. 1995 Oct;71(840):593-7.

32.

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis.

Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K, et al.

Mol Cell Biol. 1995 Jun;15(6):3336-43.

33.

Female sexual health problems in a drug dependency unit.

Morrison CL, Ruben SM, Beeching NJ.

Int J STD AIDS. 1995 May-Jun;6(3):201-3.

PMID:
7647124
34.

An estimate of the prevalence of drug misuse in Liverpool and a spatial analysis of known addiction.

Squires NF, Beeching NJ, Schlecht BJ, Ruben SM.

J Public Health Med. 1995 Mar;17(1):103-9.

PMID:
7786555
35.

Alcohol and drug misuse in prostitutes.

Morrison CL, McGee A, Ruben SM.

Addiction. 1995 Feb;90(2):292-3. No abstract available.

PMID:
7703824
36.

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.

Nicolaides NC, Papadopoulos N, Liu B, Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, et al.

Nature. 1994 Sep 1;371(6492):75-80.

PMID:
8072530
37.

Female street prostitution in Liverpool.

Morrison CL, Ruben SM, Wakefield D.

AIDS. 1994 Aug;8(8):1194-5. No abstract available.

PMID:
7986427
38.

Drug users and sick notes.

Morrison CL, Ruben SM.

BMJ. 1994 Jul 23;309(6949):271. No abstract available.

39.

Mutation of a mutL homolog in hereditary colon cancer.

Papadopoulos N, Nicolaides NC, Wei YF, Ruben SM, Carter KC, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, et al.

Science. 1994 Mar 18;263(5153):1625-9.

PMID:
8128251
40.

Acquisition of NFKB1-selective DNA binding by substitution of four amino acid residues from NFKB1 into RelA.

Coleman TA, Kunsch C, Maher M, Ruben SM, Rosen CA.

Mol Cell Biol. 1993 Jul;13(7):3850-9.

41.

New clinics for HIV testing. Improve public access.

Beeching NJ, Nye FN, Prior M, Morrison C, Ruben SM, Mutton KJ.

BMJ. 1993 May 1;306(6886):1197. No abstract available.

42.

Liaison services for pregnant drug users.

Morrison CL, Ruben SM, Siney C, Worthington M, Young L, Murphy S.

Addiction. 1993 Mar;88(3):421-2. No abstract available.

PMID:
8461859
44.
45.

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention.

Beg AA, Ruben SM, Scheinman RI, Haskill S, Rosen CA, Baldwin AS Jr.

Genes Dev. 1992 Oct;6(10):1899-913. Erratum in: Genes Dev 1992 Dec;6(12B):2664-5.

46.

Temazepam misuse in a group of injecting drug users.

Ruben SM, Morrison CL.

Br J Addict. 1992 Oct;87(10):1387-92.

PMID:
1422104
48.

I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

Ruben SM, Klement JF, Coleman TA, Maher M, Chen CH, Rosen CA.

Genes Dev. 1992 May;6(5):745-60.

49.

Identification of a naturally occurring transforming variant of the p65 subunit of NF-kappa B.

Narayanan R, Klement JF, Ruben SM, Higgins KA, Rosen CA.

Science. 1992 Apr 17;256(5055):367-70.

PMID:
1566083
50.

Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.

Ruben SM, Narayanan R, Klement JF, Chen CH, Rosen CA.

Mol Cell Biol. 1992 Feb;12(2):444-54.

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