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Items: 1 to 50 of 131

1.

Identification of a protein phosphatase 2A family member that regulates cell cycle progression in Trypanosoma brucei.

Rothberg KG, Jetton N, Hubbard JG, Powell DA, Pandarinath V, Ruben L.

Mol Biochem Parasitol. 2014 Mar-Apr;194(1-2):48-52. doi: 10.1016/j.molbiopara.2014.04.006. Epub 2014 Apr 26.

PMID:
24780109
2.

Resistance to cancer in amphibians: a role for apoptosis?

Ruben LN, Johnson RO, Clothier RH, Balls M.

Altern Lab Anim. 2013 Jul;41(3):231-4.

PMID:
23971703
3.

Comparative studies of apoptosis in Xenopus laevis and mouse thymoma cell lines.

Johnson RO, Tittle TV, Sefchick MP, Zettergren LD, Ruben LN, Clothier RH, Balls M.

Altern Lab Anim. 2013 Jul;41(3):211-8.

PMID:
23971701
4.

The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing.

Ochiana SO, Pandarinath V, Wang Z, Kapoor R, Ondrechen MJ, Ruben L, Pollastri MP.

Eur J Med Chem. 2013 Apr;62:777-84. doi: 10.1016/j.ejmech.2012.07.038. Epub 2012 Jul 31.

5.

The cell cycle as a therapeutic target against Trypanosoma brucei: Hesperadin inhibits Aurora kinase-1 and blocks mitotic progression in bloodstream forms.

Jetton N, Rothberg KG, Hubbard JG, Wise J, Li Y, Ball HL, Ruben L.

Mol Microbiol. 2009 Apr;72(2):442-58. doi: 10.1111/j.1365-2958.2009.06657.x. Epub 2009 Mar 6.

6.

The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis.

Regmi S, Rothberg KG, Hubbard JG, Ruben L.

Mol Microbiol. 2008 Nov;70(3):724-45. doi: 10.1111/j.1365-2958.2008.06443.x. Epub 2008 Sep 10.

7.

Cancer resistance in amphibians.

Ruben LN, Clothier RH, Balls M.

Altern Lab Anim. 2007 Oct;35(5):463-70. Review.

PMID:
18001168
8.

Bleomycin-induced DNA damage and repair in Xenopus laevis and Xenopus tropicalis.

Banner SH, Ruben LN, Johnson RO.

J Exp Zool A Ecol Genet Physiol. 2007 Feb 1;307(2):84-90.

PMID:
17171708
9.

The RACK1 homologue from Trypanosoma brucei is required for the onset and progression of cytokinesis.

Rothberg KG, Burdette DL, Pfannstiel J, Jetton N, Singh R, Ruben L.

J Biol Chem. 2006 Apr 7;281(14):9781-90. Epub 2006 Feb 9.

10.
11.
12.

Apoptosis and the cell cycle in Xenopus: PMA and MPMA exposure of splenocytes.

Ruben LN, Johnson RO, Bergin A, Clothier RH.

Apoptosis. 2000 Jun;5(3):225-33.

PMID:
11225844
13.

Calmodulin-binding properties of the paraflagellar rod complex from Trypanosoma brucei.

Ridgley E, Webster P, Patton C, Ruben L.

Mol Biochem Parasitol. 2000 Jul;109(2):195-201. No abstract available.

PMID:
10960180
14.

Phosphatidylserine expression on apoptotic lymphocytes of Xenopus laevis, the South African clawed toad, as a signal for macrophage recognition.

Nera MS, Vanderbeek G, Johnson RO, Ruben LN, Clothier RH.

Dev Comp Immunol. 2000 Sep-Oct;24(6-7):641-52.

PMID:
10831798
15.

Apoptosis and the cell cycle in Xenopus laevis: PHA and PMA exposure of splenocytes.

McMahan R, Johnson RO, Ruben LN, Clothier RH.

Immunol Lett. 1999 Dec 1;70(3):179-83.

PMID:
10656671
16.

Pathways involved in environmental sensing in trypanosomatids.

Parsons M, Ruben L.

Parasitol Today. 2000 Feb;16(2):56-62. Review.

PMID:
10652488
17.
18.

Adrenergic modulation of apoptosis in splenocytes of Xenopus laevis in vitro.

Haberfeld M, Johnson RO, Ruben LN, Clothier RH, Shiigi S.

Neuroimmunomodulation. 1999 May-Jun;6(3):175-81.

PMID:
10213915
19.

Expression of a Fas-like proapoptotic molecule on the lymphocytes of Xenopus laevis.

Mangurian C, Johnson RO, McMahan R, Clothier RH, Ruben LN.

Immunol Lett. 1998 Nov;64(1):31-8.

PMID:
9865599
20.

Calcium entry in Trypanosoma brucei is regulated by phospholipase A2 and arachidonic acid.

Eintracht J, Maathai R, Mellors A, Ruben L.

Biochem J. 1998 Dec 15;336 ( Pt 3):659-66.

21.

In situ lymphocyte apoptosis in larval Xenopus laevis, the South African clawed toad.

Grant P, Clothier RH, Johnson RO, Ruben LN.

Dev Comp Immunol. 1998 Jul-Aug;22(4):449-55.

PMID:
9699490
22.
23.
24.

Nuclear calcium flux in Trypanosoma brucei can be quantified with targeted aequorin.

Xiong ZH, Ruben L.

Mol Biochem Parasitol. 1996 Dec 2;83(1):57-67.

PMID:
9010842
25.

Calcium influx in Trypanosoma brucei can be induced by amphiphilic peptides and amines.

Ruben L, Akins CD, Haghighat NG, Xue L.

Mol Biochem Parasitol. 1996 Oct 30;81(2):191-200.

PMID:
8898334
26.

Genomic organization and expression of elongation factor-1 alpha genes in Trypanosoma brucei.

Ridgley EL, Xiong ZH, Kaur KJ, Ruben L.

Mol Biochem Parasitol. 1996 Jul;79(1):119-23. No abstract available.

PMID:
8844680
27.

Interleukin-2-induced mortality during the metamorphosis of Xenopus laevis.

Ruben LN, de Leon RT, Johnson RO, Bowman S, Clothier RE.

Immunol Lett. 1996 Jul;51(3):157-61.

PMID:
8832284
28.

The time course, localization and quantitation of T- and B-cell mitogen-driven apoptosis in vivo.

Grant P, Clothier RH, Johnson RO, Schott S, Ruben LN.

Immunol Lett. 1995 Sep;47(3):227-31.

PMID:
8747724
29.

The development of peripheral TNP-tolerance and suppressor function in Xenopus laevis, the South African clawed toad.

Ruben LN, Goodman AR, Johnson RO, Kaleeba JA, Clothier RH.

Dev Comp Immunol. 1995 Sep-Oct;19(5):405-15.

PMID:
8654667
30.

The gene family of EF-hand calcium-binding proteins from the flagellum of Trypanosoma brucei.

Wu Y, Deford J, Benjamin R, Lee MG, Ruben L.

Biochem J. 1994 Dec 15;304 ( Pt 3):833-41.

31.
32.

A comparison of the effects of human rIL-2 and autologous TCGF on Xenopus laevis splenocytes in vitro.

Ruben LN, Rak JC, Johnson RO, Shiigi S, Clothier RH.

Cell Immunol. 1994 Aug;157(1):300-5.

PMID:
8039250
33.

A novel heterodimeric transferrin receptor encoded by a pair of VSG expression site-associated genes in T. brucei.

Salmon D, Geuskens M, Hanocq F, Hanocq-Quertier J, Nolan D, Ruben L, Pays E.

Cell. 1994 Jul 15;78(1):75-86.

PMID:
8033214
34.

Apoptosis in the thymus of developing Xenopus laevis.

Ruben LN, Ahmadi P, Johnson RO, Buchholz DR, Clothier RH, Shiigi S.

Dev Comp Immunol. 1994 Jul-Aug;18(4):343-52.

PMID:
7883063
35.

Apoptosis in thymus of adult Xenopus laevis.

Ruben LN, Buchholz DR, Ahmadi P, Johnson RO, Clothier RH, Shiigi S.

Dev Comp Immunol. 1994 May-Jun;18(3):231-8.

PMID:
8001701
36.
38.

Impaired T cell functions during amphibian metamorphosis: IL-2 receptor expression and endogenous ligand production.

Ruben LN, Scheinman MA, Johnson RO, Shiigi S, Clothier RH, Balls M.

Mech Dev. 1992 May;37(3):167-72.

PMID:
1498041
39.
40.

Neuroendocrine regulation of immunity: the effects of noradrenaline in Xenopus laevis, the South African clawed toad.

Clothier RH, Ruben LN, Johnson RO, Parker K, Sovak M, Greenhalgh L, Ooi EE, Balls M.

Int J Neurosci. 1992 Jan;62(1-2):123-40.

PMID:
1364139
41.

Calcium homeostasis in Trypanosoma brucei. Identification of a pH-sensitive non-mitochondrial calcium pool.

Ruben L, Hutchinson A, Moehlman J.

J Biol Chem. 1991 Dec 25;266(36):24351-8.

42.

Morphological and immunological changes in the spleen of Xenopus laevis during metamorphosis.

Clothier RH, Ruben LN, Balls M, Greenhalgh L.

Res Immunol. 1991 May;142(4):360-2. Review. No abstract available.

PMID:
1925006
43.

Variant surface glycoprotein from Trypanosoma brucei clone YTat 1.1 contains a latent calmodulin-binding domain.

Ruben L, Ridgley EL, Haghighat NG, Chan E.

Mol Biochem Parasitol. 1991 May;46(1):123-36.

PMID:
1852168
44.

Thymus-replacing activity from the metamorphic spleen of Xenopus laevis.

Ruben LN, Marshall JD, Langeberg L, Johnson RO, Clothier RH.

Cytokine. 1991 Jan;3(1):28-34.

PMID:
1883954
46.
47.

Thyroid function and immune reactivity during metamorphosis in Xenopus laevis, the South African clawed toad.

Ruben LN, Clothier RH, Murphy GL, Marshall JD, Lee R, Pham T, Nobis C, Shiigi S.

Gen Comp Endocrinol. 1989 Oct;76(1):128-38.

PMID:
2532164
48.
49.

Differential cyclophosphamide sensitivity of suppressor function in Xenopus, the clawed toad.

Clothier RH, Last Z, Somauroo JD, Ruben LN, Balls M.

Dev Comp Immunol. 1989 Spring;13(2):159-66.

PMID:
2776936
50.

Amphibian metamorphosis: an immunologic opportunity!

Ruben LN, Clothier RH, Horton JD, Balls M.

Bioessays. 1989 Jan;10(1):8-12. Review.

PMID:
2653311

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