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Items: 1 to 50 of 127


Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR.

Yang P, Zeng H, Tan W, Luo X, Zheng E, Zhao L, Wei L, Ruan XZ, Chen Y, Chen Y.

FASEB J. 2020 Feb 25. doi: 10.1096/fj.201902777RR. [Epub ahead of print]


Butyrate Improves the Metabolic Disorder and Gut Microbiome Dysbiosis in Mice Induced by a High-Fat Diet.

Gao F, Lv YW, Long J, Chen JM, He JM, Ruan XZ, Zhu HB.

Front Pharmacol. 2019 Sep 13;10:1040. doi: 10.3389/fphar.2019.01040. eCollection 2019.


Nuclear FAM289-Galectin-1 interaction controls FAM289-mediated tumor promotion in malignant glioma.

Guo XR, Wu MY, Dai LJ, Huang Y, Shan MY, Ma SN, Wang J, Peng H, Ding Y, Zhang QF, Tang JM, Ruan XZ, Li DS.

J Exp Clin Cancer Res. 2019 Sep 6;38(1):394. doi: 10.1186/s13046-019-1393-7.


Lipid Metabolism Disorder and Renal Fibrosis.

Du XG, Ruan XZ.

Adv Exp Med Biol. 2019;1165:525-541. doi: 10.1007/978-981-13-8871-2_26.


The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis.

Zhou X, Zhao L, Yang P, Chen Y, Ruan XZ.

Gastroenterol Res Pract. 2019 Feb 28;2019:3480732. doi: 10.1155/2019/3480732. eCollection 2019. Review.


High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways.

Zhang X, Yang P, Luo X, Su C, Chen Y, Zhao L, Wei L, Zeng H, Varghese Z, Moorhead JF, Ruan XZ, Chen Y.

Lipids Health Dis. 2019 Mar 28;18(1):76. doi: 10.1186/s12944-019-1023-6.


CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway.

Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

J Lipid Res. 2019 Apr;60(4):844-855. doi: 10.1194/jlr.M090969. Epub 2019 Jan 20.


Caspase 3/ROCK1 pathway mediates high glucose-induced platelet microparticles shedding.

Wang GH, Ma KL, Zhang Y, Hu ZB, Liu L, Lu J, Chen PP, Lu CC, Ruan XZ, Liu BC.

Biochem Biophys Res Commun. 2019 Feb 5;509(2):596-602. doi: 10.1016/j.bbrc.2018.12.166. Epub 2018 Dec 31.


SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up-regulating autophagy in ApoE-/- mice.

Li D, Chen A, Lan T, Zou Y, Zhao L, Yang P, Qu H, Wei L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

FASEB J. 2019 Mar;33(3):3437-3450. doi: 10.1096/fj.201800975RRR. Epub 2018 Nov 21.


Platelet microparticles contribute to aortic vascular endothelial injury in diabetes via the mTORC1 pathway.

Wang GH, Ma KL, Zhang Y, Hu ZB, Liu L, Lu J, Chen PP, Lu CC, Ruan XZ, Liu BC.

Acta Pharmacol Sin. 2019 Apr;40(4):468-476. doi: 10.1038/s41401-018-0186-4. Epub 2018 Nov 16.


Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy.

Zhang Y, Ma KL, Gong YX, Wang GH, Hu ZB, Liu L, Lu J, Chen PP, Lu CC, Ruan XZ, Liu BC.

J Am Soc Nephrol. 2018 Nov;29(11):2671-2695. doi: 10.1681/ASN.2018040368. Epub 2018 Oct 19. Erratum in: J Am Soc Nephrol. 2019 Jan;30(1):182.


Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway.

Yang P, Su C, Luo X, Zeng H, Zhao L, Wei L, Zhang X, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

Cancer Lett. 2018 Dec 1;438:76-85. doi: 10.1016/j.canlet.2018.09.006. Epub 2018 Sep 11.


Fatty acid activates NLRP3 inflammasomes in mouse Kupffer cells through mitochondrial DNA release.

Pan J, Ou Z, Cai C, Li P, Gong J, Ruan XZ, He K.

Cell Immunol. 2018 Oct;332:111-120. doi: 10.1016/j.cellimm.2018.08.006. Epub 2018 Aug 10.


Activation of the CXCL16/CXCR6 pathway promotes lipid deposition in fatty livers of apolipoprotein E knockout mice and HepG2 cells.

Ma KL, Wu Y, Zhang Y, Wang GH, Hu ZB, Ruan XZ.

Am J Transl Res. 2018 Jun 15;10(6):1802-1816. eCollection 2018.


Intestinal dysbiosis activates renal renin-angiotensin system contributing to incipient diabetic nephropathy.

Lu CC, Ma KL, Ruan XZ, Liu BC.

Int J Med Sci. 2018 May 22;15(8):816-822. doi: 10.7150/ijms.25543. eCollection 2018. Review.


Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells.

Zhou X, Gao H, Guo Y, Chen Y, Ruan XZ.

Biochem Biophys Res Commun. 2018 Oct 2;504(2):387-392. doi: 10.1016/j.bbrc.2018.06.030. Epub 2018 Jun 15.


CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis.

Zhao L, Zhang C, Luo X, Wang P, Zhou W, Zhong S, Xie Y, Jiang Y, Yang P, Tang R, Pan Q, Hall AR, Luong TV, Fan J, Varghese Z, Moorhead JF, Pinzani M, Chen Y, Ruan XZ.

J Hepatol. 2018 Sep;69(3):705-717. doi: 10.1016/j.jhep.2018.04.006. Epub 2018 Apr 27.


Smooth muscle cells differentiated from mesenchymal stem cells are regulated by microRNAs and suitable for vascular tissue grafts.

Gu W, Hong X, Le Bras A, Nowak WN, Issa Bhaloo S, Deng J, Xie Y, Hu Y, Ruan XZ, Xu Q.

J Biol Chem. 2018 May 25;293(21):8089-8102. doi: 10.1074/jbc.RA118.001739. Epub 2018 Apr 11.


CD36 and lipid metabolism in the evolution of atherosclerosis.

Zhao L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

Br Med Bull. 2018 Jun 1;126(1):101-112. doi: 10.1093/bmb/ldy006. Review.


Palmitic Acid-Induced Podocyte Apoptosis via the Reactive Oxygen Species-Dependent Mitochondrial Pathway.

Liu T, Chen XM, Sun JY, Jiang XS, Wu Y, Yang S, Huang HZ, Ruan XZ, Du XG.

Kidney Blood Press Res. 2018;43(1):206-219. doi: 10.1159/000487673. Epub 2018 Feb 22.


Crosstalk of Hyperglycemia and Dyslipidemia in Diabetic Kidney Disease.

Su W, Cao R, He YC, Guan YF, Ruan XZ.

Kidney Dis (Basel). 2017 Dec;3(4):171-180. doi: 10.1159/000479874. Epub 2017 Sep 13. Review.


The Emerging Roles of Microparticles in Diabetic Nephropathy.

Lu CC, Ma KL, Ruan XZ, Liu BC.

Int J Biol Sci. 2017 Sep 5;13(9):1118-1125. doi: 10.7150/ijbs.21140. eCollection 2017. Review.


CD36 in chronic kidney disease: novel insights and therapeutic opportunities.

Yang X, Okamura DM, Lu X, Chen Y, Moorhead J, Varghese Z, Ruan XZ.

Nat Rev Nephrol. 2017 Dec;13(12):769-781. doi: 10.1038/nrneph.2017.126. Epub 2017 Sep 18. Review.


The value of Gd-BOPTA- enhanced MRIs and DWI in the diagnosis of intrahepatic mass-forming cholangiocarcinoma.

Xu CC, Tang YF, Ruan XZ, Huang QL, Sun L, Li J.

Neoplasma. 2017;64(6):945-953. doi: 10.4149/neo_2017_619.


Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells.

Gao H, Li D, Yang P, Zhao L, Wei L, Chen Y, Ruan XZ.

Biochem Biophys Res Commun. 2017 Sep 9;491(1):204-208. doi: 10.1016/j.bbrc.2017.07.077. Epub 2017 Jul 13.


Diagnostic value of four-dimensional CT angiography in arterial erectile dysfunction using 320-detector row dynamic volume CT.

Xu CC, Ruan XZ, Tang YF, Pan JH, Wang GY, Huang QL.

Biosci Rep. 2017 Aug 21;37(4). pii: BSR20170200. doi: 10.1042/BSR20170200. Print 2017 Aug 31.


Chronic Kidney Disease-Mineral and Bone Disorder.

Lee WC, Ruan XZ, Chau YY, Chen JB.

Biomed Res Int. 2017;2017:4875042. doi: 10.1155/2017/4875042. Epub 2017 Jun 19. No abstract available.


Fatty acid translocase promoted hepatitis B virus replication by upregulating the levels of hepatic cytosolic calcium.

Huang J, Zhao L, Yang P, Chen Z, Ruan XZ, Huang A, Tang N, Chen Y.

Exp Cell Res. 2017 Sep 15;358(2):360-368. doi: 10.1016/j.yexcr.2017.07.012. Epub 2017 Jul 8.


Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice.

Chen T, Lu L, Xu C, Lin X, Leung YK, Ho SM, Ruan XZ, Lian X.

Sci Rep. 2017 Jul 5;7(1):4723. doi: 10.1038/s41598-017-05053-1.


Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development.

He K, Zhu X, Liu Y, Miao C, Wang T, Li P, Zhao L, Chen Y, Gong J, Cai C, Li J, Li S, Ruan XZ, Gong J.

Oncotarget. 2017 Jun 6;8(23):37657-37672. doi: 10.18632/oncotarget.17489.


Reactive Oxygen Species Generation and Atherosclerosis.

Nowak WN, Deng J, Ruan XZ, Xu Q.

Arterioscler Thromb Vasc Biol. 2017 May;37(5):e41-e52. doi: 10.1161/ATVBAHA.117.309228. Review. No abstract available.


Liver X receptor α induces 17β-hydroxysteroid dehydrogenase-13 expression through SREBP-1c.

Su W, Peng J, Li S, Dai YB, Wang CJ, Xu H, Gao M, Ruan XZ, Gustafsson JÅ, Guan YF, Zhang XY.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E357-E367. doi: 10.1152/ajpendo.00310.2016. Epub 2017 Mar 7.


Gilbert damping in CoFeB/GaAs(001) film with enhanced in-plane uniaxial magnetic anisotropy.

Tu HQ, Liu B, Huang DW, Ruan XZ, You B, Huang ZC, Zhai Y, Gao Y, Wang J, Wei LJ, Yuan Y, Xu YB, Du J.

Sci Rep. 2017 Mar 6;7:43971. doi: 10.1038/srep43971.


Autophagy Protects against Palmitic Acid-Induced Apoptosis in Podocytes in vitro.

Jiang XS, Chen XM, Wan JM, Gui HB, Ruan XZ, Du XG.

Sci Rep. 2017 Feb 22;7:42764. doi: 10.1038/srep42764.


Association between reductions in low-density lipoprotein cholesterol with statin therapy and the risk of new-onset diabetes: a meta-analysis.

Wang S, Cai R, Yuan Y, Varghese Z, Moorhead J, Ruan XZ.

Sci Rep. 2017 Jan 10;7:39982. doi: 10.1038/srep39982.


Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway.

Zhong S, Zhao L, Wang Y, Zhang C, Liu J, Wang P, Zhou W, Yang P, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

Antioxid Redox Signal. 2017 Aug 1;27(4):201-214. doi: 10.1089/ars.2016.6808. Epub 2017 Jan 10.


Immunity, atherogenesis and vascular function.

Sun J, Zhang X, Ruan XZ.

Exp Physiol. 2016 Nov 1;101(11):1325-1326. doi: 10.1113/EP085569. No abstract available.


The Tumor-promoting Effects of FAM92A1-289 in Cervical Carcinoma Cells.

Gui H, Guo XR, Fang J, Ma SN, Wu G, Shen JH, Tu HJ, Li DS, Dai LJ, Ruan XZ.

Anticancer Res. 2016 Oct;36(10):5197-5204.


Depinning of domain walls in permalloy nanowires with asymmetric notches.

Gao Y, You B, Ruan XZ, Liu MY, Yang HL, Zhan QF, Li Z, Lei N, Zhao WS, Pan DF, Wan JG, Wu J, Tu HQ, Wang J, Zhang W, Xu YB, Du J.

Sci Rep. 2016 Sep 7;6:32617. doi: 10.1038/srep32617.


Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.

Wu W, Zhao L, Yang P, Zhou W, Li B, Moorhead JF, Varghese Z, Ruan XZ, Chen Y.

PLoS One. 2016 Jul 18;11(7):e0159512. doi: 10.1371/journal.pone.0159512. eCollection 2016.


LXRα represses LPS-induced inflammatory responses by competing with IRF3 for GRIP1 in Kupffer cells.

Miao CM, He K, Li PZ, Liu ZJ, Zhu XW, Ou ZB, Ruan XZ, Gong JP, Liu CA.

Int Immunopharmacol. 2016 Jun;35:272-279. doi: 10.1016/j.intimp.2016.04.009. Epub 2016 Apr 16.


Lipid disorder and intrahepatic renin-angiotensin system activation synergistically contribute to non-alcoholic fatty liver disease.

Wu Y, Ma KL, Zhang Y, Wen Y, Wang GH, Hu ZB, Liu L, Lu J, Chen PP, Ruan XZ, Liu BC.

Liver Int. 2016 Oct;36(10):1525-34. doi: 10.1111/liv.13131. Epub 2016 May 3.


Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury.

Zhang Y, Ma KL, Ruan XZ, Liu BC.

Int J Biol Sci. 2016 Mar 21;12(5):569-79. doi: 10.7150/ijbs.14027. eCollection 2016. Review.


Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo.

Yang P, Zhao Y, Zhao L, Yuan J, Chen Y, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

Sci Rep. 2015 Oct 9;5:14959. doi: 10.1038/srep14959.


p120-catenin participates in the progress of gastric cancer through regulating the Rac1 and Pak1 signaling pathway.

Li TF, Qin SH, Ruan XZ, Wang X.

Oncol Rep. 2015 Nov;34(5):2357-64. doi: 10.3892/or.2015.4226. Epub 2015 Aug 26.


CD36 Mediated Fatty Acid-Induced Podocyte Apoptosis via Oxidative Stress.

Hua W, Huang HZ, Tan LT, Wan JM, Gui HB, Zhao L, Ruan XZ, Chen XM, Du XG.

PLoS One. 2015 May 22;10(5):e0127507. doi: 10.1371/journal.pone.0127507. eCollection 2015.


Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice.

Zhao L, Zhong S, Qu H, Xie Y, Cao Z, Li Q, Yang P, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

Sci Rep. 2015 May 14;5:10222. doi: 10.1038/srep10222.


Activation of mTORC1 disrupted LDL receptor pathway: a potential new mechanism for the progression of non-alcoholic fatty liver disease.

Liu J, Ma KL, Zhang Y, Wu Y, Hu ZB, Lv LL, Tang RN, Liu H, Ruan XZ, Liu BC.

Int J Biochem Cell Biol. 2015 Apr;61:8-19. doi: 10.1016/j.biocel.2015.01.011. Epub 2015 Jan 23.


Inflammatory Stress Exacerbated Mesangial Foam Cell Formation and Renal Injury via Disrupting Cellular Cholesterol Homeostasis.

Zhong S, Zhao L, Li Q, Yang P, Varghese Z, Moorhead JF, Chen Y, Ruan XZ.

Inflammation. 2015;38(3):959-71. doi: 10.1007/s10753-014-0058-0.


Effects of miR-33a-5P on ABCA1/G1-mediated cholesterol efflux under inflammatory stress in THP-1 macrophages.

Mao M, Lei H, Liu Q, Chen Y, Zhao L, Li Q, Luo S, Zuo Z, He Q, Huang W, Zhang N, Zhou C, Ruan XZ.

PLoS One. 2014 Oct 17;9(10):e109722. doi: 10.1371/journal.pone.0109722. eCollection 2014.

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