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Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma.
Jin Z, Song M, Wang J, Zhu W, Sun D, Liu H, Shi G. Jin Z, et al. Front Genet. 2022 Nov 10;13:944681. doi: 10.3389/fgene.2022.944681. eCollection 2022. Front Genet. 2022. PMID: 36437949 Free PMC article.
Both mRNA and protein of these PUSs were highly diagnostic of HCC. Moreover, the CNV of PUS1, PUS7, PUS7L, and RPUSD2 was also associated with prognosis. Further functional analysis revealed that PUSs were mainly involved in pathways such as genetic information processing, …
Both mRNA and protein of these PUSs were highly diagnostic of HCC. Moreover, the CNV of PUS1, PUS7, PUS7L, and RPUSD2 was also associ …
Comprehensive gene and microRNA expression profiling reveals the crucial role of hsa-let-7i and its target genes in colorectal cancer metastasis.
Zhang P, Ma Y, Wang F, Yang J, Liu Z, Peng J, Qin H. Zhang P, et al. Mol Biol Rep. 2012 Feb;39(2):1471-8. doi: 10.1007/s11033-011-0884-1. Epub 2011 May 29. Mol Biol Rep. 2012. PMID: 21625861
In addition, the targets of hsa-let-7i were predicted by two programs TargetScan and PicTar, and target genes were validated by expression profiling in the most epresentative LoVo and Caco-2 cell lines. Eight genes including TRIM41, SOX13, SLC25A4, SEMA4F, RPUSD2, PLEKHG6, …
In addition, the targets of hsa-let-7i were predicted by two programs TargetScan and PicTar, and target genes were validated by expression p …