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Items: 1 to 20 of 390

1.

Correction: Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR.

Lian WS, Ko JY, Chen YS, Ke HC, Wu SL, Kuo CW, Wang FS.

Cell Death Dis. 2019 Oct 3;10(10):741. doi: 10.1038/s41419-019-1991-5.

2.

DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis.

Barroso-Chinea P, Luis-Ravelo D, Fumagallo-Reading F, Castro-Hernandez J, Salas-Hernandez J, Rodriguez-Nuñez J, Febles-Casquero A, Cruz-Muros I, Afonso-Oramas D, Abreu-Gonzalez P, Moratalla R, Millan MJ, Gonzalez-Hernandez T.

Autophagy. 2019 Oct 2:1-17. doi: 10.1080/15548627.2019.1668606. [Epub ahead of print]

PMID:
31538542
3.

mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation.

Asrani K, Murali S, Lam B, Na CH, Phatak P, Sood A, Kaur H, Khan Z, Noë M, Anchoori RK, Talbot CC Jr, Smith B, Skaro M, Lotan TL.

J Clin Invest. 2019 Sep 17. pii: 128287. doi: 10.1172/JCI128287. [Epub ahead of print]

4.

TSC1/mTOR-controlled metabolic-epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis.

Shi L, Chen X, Zang A, Li T, Hu Y, Ma S, Lü M, Yin H, Wang H, Zhang X, Zhang B, Leng Q, Yang J, Xiao H.

PLoS Biol. 2019 Aug 21;17(8):e3000420. doi: 10.1371/journal.pbio.3000420. eCollection 2019 Aug.

5.

mTORC1 and CB1 receptor signaling regulate excitatory glutamatergic inputs onto the hypothalamic paraventricular nucleus in response to energy availability.

Mazier W, Saucisse N, Simon V, Cannich A, Marsicano G, Massa F, Cota D.

Mol Metab. 2019 Oct;28:151-159. doi: 10.1016/j.molmet.2019.08.005. Epub 2019 Aug 8.

6.

Regulation of YAP by Mammalian Target of Rapamycin Complex 1 in Endothelial Cells Controls Blood Pressure Through COX-2/mPGES-1/PGE2 Cascade.

Yao L, He J, Li B, Yan M, Wang H, Tan L, Liu M, Lv X, Lv H, Zhang X, Chen C, Wang D, Yu Y, Huang Y, Zhu Y, Ai D.

Hypertension. 2019 Oct;74(4):936-946. doi: 10.1161/HYPERTENSIONAHA.119.12834. Epub 2019 Aug 5.

PMID:
31378107
7.

Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction.

Jones I, Hägglund AC, Carlsson L.

Biol Open. 2019 Aug 1;8(8). pii: bio044370. doi: 10.1242/bio.044370.

8.

Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly.

Cuéllar J, Ludlam WG, Tensmeyer NC, Aoba T, Dhavale M, Santiago C, Bueno-Carrasco MT, Mann MJ, Plimpton RL, Makaju A, Franklin S, Willardson BM, Valpuesta JM.

Nat Commun. 2019 Jun 28;10(1):2865. doi: 10.1038/s41467-019-10781-1.

9.

SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease.

Fernández-Santiago R, Martín-Flores N, Antonelli F, Cerquera C, Moreno V, Bandres-Ciga S, Manduchi E, Tolosa E, Singleton AB, Moore JH; International Parkinson's Disease Genomics Consortium, Martí MJ, Ezquerra M, Malagelada C.

Mov Disord. 2019 Sep;34(9):1333-1344. doi: 10.1002/mds.27770. Epub 2019 Jun 24.

PMID:
31234232
10.

The double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis.

Yang H, Ni HM, Ding WX.

Autophagy. 2019 Sep;15(9):1671-1673. doi: 10.1080/15548627.2019.1634445. Epub 2019 Jun 23.

PMID:
31216956
11.

Longitudinal study of leukocyte DNA methylation and biomarkers for cancer risk in older adults.

Bartlett AH, Liang JW, Sandoval-Sierra JV, Fowke JH, Simonsick EM, Johnson KC, Mozhui K.

Biomark Res. 2019 May 28;7:10. doi: 10.1186/s40364-019-0161-3. eCollection 2019.

12.

DDR1 (discoidin domain receptor tyrosine kinase 1) drives glioblastoma therapy resistance by modulating autophagy.

Vehlow A, Cordes N.

Autophagy. 2019 Aug;15(8):1487-1488. doi: 10.1080/15548627.2019.1618540. Epub 2019 May 23.

PMID:
31117874
13.

Array-based DNA methylation profiling reveals peripheral blood differential methylation in male infertility.

Sarkar S, Sujit KM, Singh V, Pandey R, Trivedi S, Singh K, Gupta G, Rajender S.

Fertil Steril. 2019 Jul;112(1):61-72.e1. doi: 10.1016/j.fertnstert.2019.03.020. Epub 2019 May 15.

PMID:
31103287
14.

The MTORC1-mediated autophagy is regulated by the FBXW7-SHOC2-RPTOR axis.

Xie CM, Sun Y.

Autophagy. 2019 Aug;15(8):1470-1472. doi: 10.1080/15548627.2019.1609864. Epub 2019 May 3.

PMID:
31010381
15.

Genetic variants in the liver kinase B1-AMP-activated protein kinase pathway genes and pancreatic cancer risk.

Xu X, Qian D, Liu H, Cruz D, Luo S, Walsh KM, Abbruzzese JL, Zhang X, Wei Q.

Mol Carcinog. 2019 Aug;58(8):1338-1348. doi: 10.1002/mc.23018. Epub 2019 Apr 17.

PMID:
30997723
16.

Hepatoid adenocarcinoma of the stomach: a unique subgroup with distinct clinicopathological and molecular features.

Wang Y, Sun L, Li Z, Gao J, Ge S, Zhang C, Yuan J, Wang X, Li J, Lu Z, Gong J, Lu M, Zhou J, Peng Z, Shen L, Zhang X.

Gastric Cancer. 2019 Apr 15. doi: 10.1007/s10120-019-00965-5. [Epub ahead of print]

PMID:
30989433
17.

Identification of suitable reference genes for gene expression studies in rat skeletal muscle following sciatic nerve crush injury.

Wang X, Zhao H, Ni J, Pan J, Hua H, Wang Y.

Mol Med Rep. 2019 May;19(5):4377-4387. doi: 10.3892/mmr.2019.10102. Epub 2019 Mar 28.

18.

Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function.

Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, Lai W, Pan X, You T, Luo H, Guan X, Deng Y, Yuan S, Chu J, Namaka M, Hughes T, Ye L, Yu J, Li X, Deng Y.

Nat Commun. 2018 Nov 19;9(1):4874. doi: 10.1038/s41467-018-07277-9.

19.

MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca2+ communication: a dead end in cancer cells.

Ahumada-Castro U, Silva-Pavez E, Lovy A, Pardo E, Molgό J, Cárdenas C.

Autophagy. 2019 Feb;15(2):358-361. doi: 10.1080/15548627.2018.1537769. Epub 2018 Oct 29.

PMID:
30351219
20.

Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice.

Onufer EJ, Tay S, Barron LK, Courtney CM, Warner BW, Guo J.

Biochem Biophys Res Commun. 2018 Nov 10;505(4):1174-1179. doi: 10.1016/j.bbrc.2018.10.040. Epub 2018 Oct 12.

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