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Items: 11


The evolution of lifespan and age-dependent cancer risk.

Rozhok AI, DeGregori J.

Trends Cancer. 2016 Oct;2(10):552-560. doi: 10.1016/j.trecan.2016.09.004.


Coupling an EML4-ALK-centric interactome with RNA interference identifies sensitizers to ALK inhibitors.

Zhang G, Scarborough H, Kim J, Rozhok AI, Chen YA, Zhang X, Song L, Bai Y, Fang B, Liu RZ, Koomen J, Tan AC, Degregori J, Haura EB.

Sci Signal. 2016 Oct 18;9(450):rs12.


Spatial Proximity to Fibroblasts Impacts Molecular Features and Therapeutic Sensitivity of Breast Cancer Cells Influencing Clinical Outcomes.

Marusyk A, Tabassum DP, Janiszewska M, Place AE, Trinh A, Rozhok AI, Pyne S, Guerriero JL, Shu S, Ekram M, Ishkin A, Cahill DP, Nikolsky Y, Chan TA, Rimawi MF, Hilsenbeck S, Schiff R, Osborne KC, Letai A, Polyak K.

Cancer Res. 2016 Nov 15;76(22):6495-6506. doi: 10.1158/0008-5472.CAN-16-1457. Epub 2016 Sep 26.


ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.

Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678. Epub 2016 Oct 10.


Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia.

Rozhok AI, Salstrom JL, DeGregori J.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1050-5. doi: 10.1073/pnas.1509333113. Epub 2016 Jan 11.


Toward an evolutionary model of cancer: Considering the mechanisms that govern the fate of somatic mutations.

Rozhok AI, DeGregori J.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8914-21. doi: 10.1073/pnas.1501713112.


A Critical Examination of the "Bad Luck" Explanation of Cancer Risk.

Rozhok AI, Wahl GM, DeGregori J.

Cancer Prev Res (Phila). 2015 Sep;8(9):762-4. doi: 10.1158/1940-6207.CAPR-15-0229. Epub 2015 Jun 29.


Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects.

Fleenor CJ, Rozhok AI, Zaberezhnyy V, Mathew D, Kim J, Tan AC, Bernstein ID, DeGregori J.

Stem Cells. 2015 Apr;33(4):1345-58. doi: 10.1002/stem.1936.


On the persistence of P element in cultured lineages of Drosophila melanogaster.

Rozhok AI, Ievdokymenko KS, Kozeretska IA.

Tsitol Genet. 2012 Jul-Aug;46(4):55-8.


DNA methylation in Drosophila melanogaster may depend on lineage heterogeneity.

Redchuk TA, Rozhok AI, Zhuk OW, Kozeretska IA, Mousseau TA.

Tsitol Genet. 2012 Jan-Feb;46(1):75-9.


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