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Items: 26

1.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, Ebneth A, Roevens P, Royaux I, Peeters PJ.

Stem Cell Reports. 2019 Aug 13;13(2):434-435. doi: 10.1016/j.stemcr.2019.07.007. No abstract available.

2.

Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis.

Miles LA, Hermans SJ, Crespi GAN, Gooi JH, Doughty L, Nero TL, Markulić J, Ebneth A, Wroblowski B, Oehlrich D, Trabanco AA, Rives ML, Royaux I, Hancock NC, Parker MW.

iScience. 2019 Sep 27;19:110-118. doi: 10.1016/j.isci.2019.07.023. Epub 2019 Jul 19.

3.

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study.

Volpato V, Smith J, Sandor C, Ried JS, Baud A, Handel A, Newey SE, Wessely F, Attar M, Whiteley E, Chintawar S, Verheyen A, Barta T, Lako M, Armstrong L, Muschet C, Artati A, Cusulin C, Christensen K, Patsch C, Sharma E, Nicod J, Brownjohn P, Stubbs V, Heywood WE, Gissen P, De Filippis R, Janssen K, Reinhardt P, Adamski J, Royaux I, Peeters PJ, Terstappen GC, Graf M, Livesey FJ, Akerman CJ, Mills K, Bowden R, Nicholson G, Webber C, Cader MZ, Lakics V.

Stem Cell Reports. 2018 Oct 9;11(4):897-911. doi: 10.1016/j.stemcr.2018.08.013. Epub 2018 Sep 20.

4.

Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.

Verheyen A, Diels A, Reumers J, Van Hoorde K, Van den Wyngaert I, van Outryve d'Ydewalle C, De Bondt A, Kuijlaars J, De Muynck L, De Hoogt R, Bretteville A, Jaensch S, Buist A, Cabrera-Socorro A, Wray S, Ebneth A, Roevens P, Royaux I, Peeters PJ.

Stem Cell Reports. 2018 Aug 14;11(2):363-379. doi: 10.1016/j.stemcr.2018.06.022. Epub 2018 Jul 26. Erratum in: Stem Cell Reports. 2019 Aug 13;13(2):434-435.

5.

Development of a Scalable, High-Throughput-Compatible Assay to Detect Tau Aggregates Using iPSC-Derived Cortical Neurons Maintained in a Three-Dimensional Culture Format.

Medda X, Mertens L, Versweyveld S, Diels A, Barnham L, Bretteville A, Buist A, Verheyen A, Royaux I, Ebneth A, Cabrera-Socorro A.

J Biomol Screen. 2016 Sep;21(8):804-15. doi: 10.1177/1087057116638029. Epub 2016 Mar 16.

PMID:
26984927
6.

Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment.

Daniëls VW, Smans K, Royaux I, Chypre M, Swinnen JV, Zaidi N.

PLoS One. 2014 Sep 12;9(9):e106913. doi: 10.1371/journal.pone.0106913. eCollection 2014.

7.

ATP citrate lyase knockdown induces growth arrest and apoptosis through different cell- and environment-dependent mechanisms.

Zaidi N, Royaux I, Swinnen JV, Smans K.

Mol Cancer Ther. 2012 Sep;11(9):1925-35. doi: 10.1158/1535-7163.MCT-12-0095. Epub 2012 Jun 20.

8.

Corticotropin releasing factor-induced ERK phosphorylation in AtT20 cells occurs via a cAMP-dependent mechanism requiring EPAC2.

Van Kolen K, Dautzenberg FM, Verstraeten K, Royaux I, De Hoogt R, Gutknecht E, Peeters PJ.

Neuropharmacology. 2010 Jan;58(1):135-44. doi: 10.1016/j.neuropharm.2009.06.022. Epub 2009 Jun 30. Erratum in: Neuropharmacology. 2010 Feb;58(2):559. Dautzenberg, Frank M [added].

PMID:
19573542
9.

Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus.

Anesti AM, Peeters PJ, Royaux I, Coffin RS.

Nucleic Acids Res. 2008 Aug;36(14):e86. doi: 10.1093/nar/gkn371. Epub 2008 Jun 25.

10.

Loss of KCNJ10 protein expression abolishes endocochlear potential and causes deafness in Pendred syndrome mouse model.

Wangemann P, Itza EM, Albrecht B, Wu T, Jabba SV, Maganti RJ, Lee JH, Everett LA, Wall SM, Royaux IE, Green ED, Marcus DC.

BMC Med. 2004 Aug 20;2:30.

11.

Localization and functional studies of pendrin in the mouse inner ear provide insight about the etiology of deafness in pendred syndrome.

Royaux IE, Belyantseva IA, Wu T, Kachar B, Everett LA, Marcus DC, Green ED.

J Assoc Res Otolaryngol. 2003 Sep;4(3):394-404.

12.

Deoxycorticosterone upregulates PDS (Slc26a4) in mouse kidney: role of pendrin in mineralocorticoid-induced hypertension.

Verlander JW, Hassell KA, Royaux IE, Glapion DM, Wang ME, Everett LA, Green ED, Wall SM.

Hypertension. 2003 Sep;42(3):356-62. Epub 2003 Aug 18.

PMID:
12925556
13.

Localization of pendrin in mouse kidney.

Wall SM, Hassell KA, Royaux IE, Green ED, Chang JY, Shipley GL, Verlander JW.

Am J Physiol Renal Physiol. 2003 Jan;284(1):F229-41. Epub 2002 Aug 27.

14.

Localization of the ammonium transporter proteins RhBG and RhCG in mouse kidney.

Verlander JW, Miller RT, Frank AE, Royaux IE, Kim YH, Weiner ID.

Am J Physiol Renal Physiol. 2003 Feb;284(2):F323-37. Epub 2002 Oct 8.

15.

Retention of pendrin in the endoplasmic reticulum is a major mechanism for Pendred syndrome.

Rotman-Pikielny P, Hirschberg K, Maruvada P, Suzuki K, Royaux IE, Green ED, Kohn LD, Lippincott-Schwartz J, Yen PM.

Hum Mol Genet. 2002 Oct 1;11(21):2625-33.

PMID:
12354788
16.

Pendrin immunoreactivity in the gill epithelium of a euryhaline elasmobranch.

Piermarini PM, Verlander JW, Royaux IE, Evans DH.

Am J Physiol Regul Integr Comp Physiol. 2002 Oct;283(4):R983-92.

17.

Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells.

Yoshida A, Taniguchi S, Hisatome I, Royaux IE, Green ED, Kohn LD, Suzuki K.

J Clin Endocrinol Metab. 2002 Jul;87(7):3356-61.

PMID:
12107249
18.

Expression of PDS/Pds, the Pendred syndrome gene, in endometrium.

Suzuki K, Royaux IE, Everett LA, Mori-Aoki A, Suzuki S, Nakamura K, Sakai T, Katoh R, Toda S, Green ED, Kohn LD.

J Clin Endocrinol Metab. 2002 Feb;87(2):938.

PMID:
11836344
19.

Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion.

Royaux IE, Wall SM, Karniski LP, Everett LA, Suzuki K, Knepper MA, Green ED.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):4221-6.

20.

Effects of thyroglobulin and pendrin on iodide flux through the thyrocyte.

Kohn LD, Suzuki K, Nakazato M, Royaux I, Green ED.

Trends Endocrinol Metab. 2001 Jan-Feb;12(1):10-6. Review.

PMID:
11137035
21.

Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells.

Royaux IE, Suzuki K, Mori A, Katoh R, Everett LA, Kohn LD, Green ED.

Endocrinology. 2000 Feb;141(2):839-45.

PMID:
10650967
22.

Evolutionarily conserved, alternative splicing of reelin during brain development.

Lambert de Rouvroit C, Bernier B, Royaux I, de Bergeyck V, Goffinet AM.

Exp Neurol. 1999 Apr;156(2):229-38.

PMID:
10328932
23.

A DnaJ-like gene, Hsj2, maps to mouse chromosome 5, at approximately 24 cM from the centromere.

Royaux I, Minner F, Goffinet AM, de Rouvroit CL.

Genomics. 1998 Nov 1;53(3):415. No abstract available.

PMID:
9799614
24.

Genomic organization of the mouse reelin gene.

Royaux I, Lambert de Rouvroit C, D'Arcangelo G, Demirov D, Goffinet AM.

Genomics. 1997 Dec 1;46(2):240-50.

PMID:
9417911
25.

Reln(rl-Alb2), an allele of reeler isolated from a chlorambucil screen, is due to an IAP insertion with exon skipping.

Royaux I, Bernier B, Montgomery JC, Flaherty L, Goffinet AM.

Genomics. 1997 Jun 15;42(3):479-82.

PMID:
9205121
26.

A YAC contig containing the reeler locus with preliminary characterization of candidate gene fragments.

Bar I, Lambert De Rouvroit C, Royaux I, Krizman DB, Dernoncourt C, Ruelle D, Beckers MC, Goffinet AM.

Genomics. 1995 Apr 10;26(3):543-9.

PMID:
7607678

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