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Items: 40


The role of Alu-derived RNAs in Alzheimer's and other neurodegenerative conditions.

Polesskaya O, Kananykhina E, Roy-Engel AM, Nazarenko O, Kulemzina I, Baranova A, Vassetsky Y, Myakishev-Rempel M.

Med Hypotheses. 2018 Jun;115:29-34. doi: 10.1016/j.mehy.2018.03.008. Epub 2018 Mar 21.


Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells.

Ade CM, Derbes RS, Wagstaff BJ, Linker SB, White TB, Deharo D, Belancio VP, Ivics Z, Roy-Engel AM.

Gene. 2018 Feb 5;642:188-198. doi: 10.1016/j.gene.2017.11.033. Epub 2017 Nov 14.


The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition.

Servant G, Streva VA, Derbes RS, Wijetunge MI, Neeland M, White TB, Belancio VP, Roy-Engel AM, Deininger PL.

Genetics. 2017 Jan;205(1):139-153. doi: 10.1534/genetics.116.188680. Epub 2016 Nov 14.


Carcinogenic effects of oil dispersants: A KEGG pathway-based RNA-seq study of human airway epithelial cells.

Liu YZ, Zhang L, Roy-Engel AM, Saito S, Lasky JA, Wang G, Wang H.

Gene. 2017 Feb 20;602:16-23. doi: 10.1016/j.gene.2016.11.028. Epub 2016 Nov 16.


Heavy metal and junk DNA.

Roy-Engel AM.

Mob Genet Elements. 2016 Sep 20;6(5):e1234428. eCollection 2016. No abstract available.


Meeting report for Odd Pols 2016: Ann Arbor 2.0.

Roy-Engel AM.

Gene. 2017 May 15;612:1-4. doi: 10.1016/j.gene.2016.09.029. Epub 2016 Sep 21.


Heavy Metal Exposure Influences Double Strand Break DNA Repair Outcomes.

Morales ME, Derbes RS, Ade CM, Ortego JC, Stark J, Deininger PL, Roy-Engel AM.

PLoS One. 2016 Mar 11;11(3):e0151367. doi: 10.1371/journal.pone.0151367. eCollection 2016.


SINE Retrotransposition: Evaluation of Alu Activity and Recovery of De Novo Inserts.

Ade C, Roy-Engel AM.

Methods Mol Biol. 2016;1400:183-201. doi: 10.1007/978-1-4939-3372-3_13.


The impact of oil spill to lung health--Insights from an RNA-seq study of human airway epithelial cells.

Liu YZ, Roy-Engel AM, Baddoo MC, Flemington EK, Wang G, Wang H.

Gene. 2016 Mar 1;578(1):38-51. doi: 10.1016/j.gene.2015.12.016. Epub 2015 Dec 9.


Altering Genomic Integrity: Heavy Metal Exposure Promotes Transposable Element-Mediated Damage.

Morales ME, Servant G, Ade C, Roy-Engel AM.

Biol Trace Elem Res. 2015 Jul;166(1):24-33. doi: 10.1007/s12011-015-0298-3. Epub 2015 Mar 14. Review.


Meeting report for "OddPols" 2014: the odds invite an even.

Roy-Engel AM.

Gene. 2015 Feb 1;556(1):1-6. doi: 10.1016/j.gene.2014.10.053. Epub 2014 Oct 31.


Alu elements: an intrinsic source of human genome instability.

Ade C, Roy-Engel AM, Deininger PL.

Curr Opin Virol. 2013 Dec;3(6):639-45. doi: 10.1016/j.coviro.2013.09.002. Epub 2013 Sep 27. Review.


Effects of COREXIT dispersants on cytotoxicity parameters in a cultured human bronchial airway cells, BEAS-2B.

Shi Y, Roy-Engel AM, Wang H.

J Toxicol Environ Health A. 2013;76(13):827-35. doi: 10.1080/15287394.2013.821396.


Meeting report for Odd Pols 2012.

Roy-Engel AM, Moss T, Maraia RJ.

Gene. 2013 Aug 15;526(1):1-6. doi: 10.1016/j.gene.2013.04.009. Epub 2013 Apr 20.


A tale of an A-tail: The lifeline of a SINE.

Roy-Engel AM.

Mob Genet Elements. 2012 Nov 1;2(6):282-286. No abstract available.


Molecular reconstruction of extinct LINE-1 elements and their interaction with nonautonomous elements.

Wagstaff BJ, Kroutter EN, Derbes RS, Belancio VP, Roy-Engel AM.

Mol Biol Evol. 2013 Jan;30(1):88-99. doi: 10.1093/molbev/mss202. Epub 2012 Aug 23.


Rescuing Alu: recovery of new inserts shows LINE-1 preserves Alu activity through A-tail expansion.

Wagstaff BJ, Hedges DJ, Derbes RS, Campos Sanchez R, Chiaromonte F, Makova KD, Roy-Engel AM.

PLoS Genet. 2012;8(8):e1002842. doi: 10.1371/journal.pgen.1002842. Epub 2012 Aug 9.


Alu expression in human cell lines and their retrotranspositional potential.

Oler AJ, Traina-Dorge S, Derbes RS, Canella D, Cairns BR, Roy-Engel AM.

Mob DNA. 2012 Jun 20;3(1):11. doi: 10.1186/1759-8753-3-11.


LINEs, SINEs and other retroelements: do birds of a feather flock together?

Roy-Engel AM.

Front Biosci (Landmark Ed). 2012 Jan 1;17:1345-61. Review.


Evolutionary conservation of the functional modularity of primate and murine LINE-1 elements.

Wagstaff BJ, Barnerssoi M, Roy-Engel AM.

PLoS One. 2011 May 10;6(5):e19672. doi: 10.1371/journal.pone.0019672.


All y'all need to know 'bout retroelements in cancer.

Belancio VP, Roy-Engel AM, Deininger PL.

Semin Cancer Biol. 2010 Aug;20(4):200-10. doi: 10.1016/j.semcancer.2010.06.001. Epub 2010 Jun 25. Review.


Somatic expression of LINE-1 elements in human tissues.

Belancio VP, Roy-Engel AM, Pochampally RR, Deininger P.

Nucleic Acids Res. 2010 Jul;38(12):3909-22. doi: 10.1093/nar/gkq132. Epub 2010 Mar 9.


LINE dancing in the human genome: transposable elements and disease.

Belancio VP, Deininger PL, Roy-Engel AM.

Genome Med. 2009 Oct 27;1(10):97. doi: 10.1186/gm97.


The RNA polymerase dictates ORF1 requirement and timing of LINE and SINE retrotransposition.

Kroutter EN, Belancio VP, Wagstaff BJ, Roy-Engel AM.

PLoS Genet. 2009 Apr;5(4):e1000458. doi: 10.1371/journal.pgen.1000458. Epub 2009 Apr 24.


Diverse cis factors controlling Alu retrotransposition: what causes Alu elements to die?

Comeaux MS, Roy-Engel AM, Hedges DJ, Deininger PL.

Genome Res. 2009 Apr;19(4):545-55. doi: 10.1101/gr.089789.108. Epub 2009 Mar 9.


LINE-1 ORF1 protein enhances Alu SINE retrotransposition.

Wallace N, Wagstaff BJ, Deininger PL, Roy-Engel AM.

Gene. 2008 Aug 1;419(1-2):1-6. doi: 10.1016/j.gene.2008.04.007. Epub 2008 Apr 24.


ERCC1/XPF limits L1 retrotransposition.

Gasior SL, Roy-Engel AM, Deininger PL.

DNA Repair (Amst). 2008 Jun 1;7(6):983-9. doi: 10.1016/j.dnarep.2008.02.006. Epub 2008 Apr 18.


The impact of multiple splice sites in human L1 elements.

Belancio VP, Roy-Engel AM, Deininger P.

Gene. 2008 Mar 31;411(1-2):38-45. doi: 10.1016/j.gene.2007.12.022. Epub 2008 Jan 11.


The L1 retrotranspositional stimulation by particulate and soluble cadmium exposure is independent of the generation of DNA breaks.

Kale SP, Carmichael MC, Harris K, Roy-Engel AM.

Int J Environ Res Public Health. 2006 Jun;3(2):121-8.


Heavy metals stimulate human LINE-1 retrotransposition.

Kale SP, Moore L, Deininger PL, Roy-Engel AM.

Int J Environ Res Public Health. 2005 Apr;2(1):14-23.


Nickel stimulates L1 retrotransposition by a post-transcriptional mechanism.

El-Sawy M, Kale SP, Dugan C, Nguyen TQ, Belancio V, Bruch H, Roy-Engel AM, Deininger PL.

J Mol Biol. 2005 Nov 25;354(2):246-57. Epub 2005 Oct 4.


Human retroelements may introduce intragenic polyadenylation signals.

Roy-Engel AM, El-Sawy M, Farooq L, Odom GL, Perepelitsa-Belancio V, Bruch H, Oyeniran OO, Deininger PL.

Cytogenet Genome Res. 2005;110(1-4):365-71.


Potential for retroposition by old Alu subfamilies.

Johanning K, Stevenson CA, Oyeniran OO, Gozal YM, Roy-Engel AM, Jurka J, Deininger PL.

J Mol Evol. 2003 Jun;56(6):658-64.


Active Alu element "A-tails": size does matter.

Roy-Engel AM, Salem AH, Oyeniran OO, Deininger L, Hedges DJ, Kilroy GE, Batzer MA, Deininger PL.

Genome Res. 2002 Sep;12(9):1333-44.


Shared protein components of SINE RNPs.

West N, Roy-Engel AM, Imataka H, Sonenberg N, Deininger P.

J Mol Biol. 2002 Aug 16;321(3):423-32.


Non-traditional Alu evolution and primate genomic diversity.

Roy-Engel AM, Carroll ML, El-Sawy M, Salem AH, Garber RK, Nguyen SV, Deininger PL, Batzer MA.

J Mol Biol. 2002 Mar 8;316(5):1033-40.


Alu insertion polymorphisms for the study of human genomic diversity.

Roy-Engel AM, Carroll ML, Vogel E, Garber RK, Nguyen SV, Salem AH, Batzer MA, Deininger PL.

Genetics. 2001 Sep;159(1):279-90.


Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity.

Carroll ML, Roy-Engel AM, Nguyen SV, Salem AH, Vogel E, Vincent B, Myers J, Ahmad Z, Nguyen L, Sammarco M, Watkins WS, Henke J, Makalowski W, Jorde LB, Deininger PL, Batzer MA.

J Mol Biol. 2001 Aug 3;311(1):17-40.


Cis-acting influences on Alu RNA levels.

Alemán C, Roy-Engel AM, Shaikh TH, Deininger PL.

Nucleic Acids Res. 2000 Dec 1;28(23):4755-61.

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