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Items: 1 to 50 of 53

1.

Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis.

Barahman M, Zhang W, Harris HY, Aiyer A, Kabarriti R, Kinkhabwala M, Roy-Chowdhury N, Beck AP, Scanlan TS, Roy-Chowdhury J, Asp P, Guha C.

J Hepatol. 2019 Jun;70(6):1170-1179. doi: 10.1016/j.jhep.2019.01.010. Epub 2019 Jan 14.

PMID:
30654068
2.

Genes and Pathways Promoting Long-Term Liver Repopulation by Ex Vivo hYAP-ERT2 Transduced Hepatocytes and Treatment of Jaundice in Gunn Rats.

Peterson EA, Polgar Z, Devakanmalai GS, Li Y, Jaber FL, Zhang W, Wang X, Iqbal NJ, Murray JW, Roy-Chowdhury N, Quispe-Tintaya W, Maslov AY, Tchaikovskaya TL, Sharma Y, Rogler LE, Gupta S, Zhu L, Roy-Chowdhury J, Shafritz DA.

Hepatol Commun. 2018 Nov 20;3(1):129-146. doi: 10.1002/hep4.1278. eCollection 2019 Jan.

3.

Hepatocyte Transplantation: Quo Vadis?

Barahman M, Asp P, Roy-Chowdhury N, Kinkhabwala M, Roy-Chowdhury J, Kabarriti R, Guha C.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):922-934. doi: 10.1016/j.ijrobp.2018.11.016. Epub 2018 Nov 29. Review.

PMID:
30503786
4.

Impact of arsenic contaminated groundwater used during domestic scale post harvesting of paddy crop in West Bengal: Arsenic partitioning in raw and parboiled whole grain.

Roy Chowdhury N, Ghosh S, Joardar M, Kar D, Roychowdhury T.

Chemosphere. 2018 Nov;211:173-184. doi: 10.1016/j.chemosphere.2018.07.128. Epub 2018 Jul 25.

PMID:
30071430
5.

"Chocolate" Gold Nanoparticles-One Pot Synthesis and Biocompatibility.

Roy Chowdhury N, Cowin AJ, Zilm P, Vasilev K.

Nanomaterials (Basel). 2018 Jul 5;8(7). pii: E496. doi: 10.3390/nano8070496.

6.

Drug- and Drug Abuse-Associated Hyperbilirubinemia: Experience With Atazanavir.

Roy-Chowdhury J, Roy-Chowdhury N, Listowsky I, Wolkoff AW.

Clin Pharmacol Drug Dev. 2017 Mar;6(2):140-146. doi: 10.1002/cpdd.314.

7.

Gunn Rats as a Surrogate Model for Evaluation of Hepatocyte Transplantation-Based Therapies of Crigler-Najjar Syndrome Type 1.

Polgar Z, Li Y, Li Wang X, Guha C, Roy-Chowdhury N, Roy-Chowdhury J.

Methods Mol Biol. 2017;1506:131-147.

PMID:
27830550
8.

Hepatocyte-like cells derived from induced pluripotent stem cells.

Roy-Chowdhury N, Wang X, Guha C, Roy-Chowdhury J.

Hepatol Int. 2017 Jan;11(1):54-69. doi: 10.1007/s12072-016-9757-y. Epub 2016 Aug 17. Review.

PMID:
27530815
9.

Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology.

Sauer V, Tchaikovskaya T, Wang X, Li Y, Zhang W, Tar K, Polgar Z, Ding J, Guha C, Fox IJ, Roy-Chowdhury N, Roy-Chowdhury J.

Cell Transplant. 2016 Dec 13;25(12):2221-2243. doi: 10.3727/096368916X692014. Epub 2016 Jun 9.

PMID:
27512979
10.

Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes.

Chen Y, Li Y, Wang X, Zhang W, Sauer V, Chang CJ, Han B, Tchaikovskaya T, Avsar Y, Tafaleng E, Madhusudana Girija S, Tar K, Polgar Z, Strom S, Bouhassira EE, Guha C, Fox IJ, Roy-Chowdhury J, Roy-Chowdhury N.

Stem Cell Reports. 2015 Jul 14;5(1):22-30. doi: 10.1016/j.stemcr.2015.04.017. Epub 2015 Jun 11.

11.

Induced pluripotent stem cells as a source of hepatocytes.

Sauer V, Roy-Chowdhury N, Guha C, Roy-Chowdhury J.

Curr Pathobiol Rep. 2014 Mar;2(1):11-20.

12.

Single liver lobe repopulation with wildtype hepatocytes using regional hepatic irradiation cures jaundice in Gunn rats.

Zhou H, Dong X, Kabarriti R, Chen Y, Avsar Y, Wang X, Ding J, Liu L, Fox IJ, Roy-Chowdhury J, Roy-Chowdhury N, Guha C.

PLoS One. 2012;7(10):e46775. doi: 10.1371/journal.pone.0046775. Epub 2012 Oct 16.

13.

Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes.

Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, Wong RJ, Avsar Y, Guha C, Perlmutter DH, Fox IJ, Roy-Chowdhury J.

J Clin Invest. 2011 May;121(5):1930-4. doi: 10.1172/JCI45260. Epub 2011 Apr 18.

14.

Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice.

Bhanja P, Saha S, Kabarriti R, Liu L, Roy-Chowdhury N, Roy-Chowdhury J, Sellers RS, Alfieri AA, Guha C.

PLoS One. 2009 Nov 24;4(11):e8014. doi: 10.1371/journal.pone.0008014.

15.

Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon.

Wang X, Sarkar DP, Mani P, Steer CJ, Chen Y, Guha C, Chandrasekhar V, Chaudhuri A, Roy-Chowdhury N, Kren BT, Roy-Chowdhury J.

Hepatology. 2009 Sep;50(3):815-24. doi: 10.1002/hep.23060.

16.

Fatal kernicterus in a girl deficient in glucose-6-phosphate dehydrogenase: a paradigm of synergistic heterozygosity.

Zangen S, Kidron D, Gelbart T, Roy-Chowdhury N, Wang X, Kaplan M.

J Pediatr. 2009 Apr;154(4):616-9. doi: 10.1016/j.jpeds.2008.10.049.

PMID:
19324225
17.

Ex vivo gene transfer into hepatocytes.

Wang X, Mani P, Sarkar DP, Roy-Chowdhury N, Roy-Chowdhury J.

Methods Mol Biol. 2009;481:117-40. doi: 10.1007/978-1-59745-201-4_11. Review.

PMID:
19096805
18.

Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation.

Yamanouchi K, Zhou H, Roy-Chowdhury N, Macaluso F, Liu L, Yamamoto T, Yannam GR, Enke C, Solberg TD, Adelson AB, Platt JL, Fox IJ, Roy-Chowdhury J, Guha C.

Hepatology. 2009 Jan;49(1):258-67. doi: 10.1002/hep.22573.

19.

Correction of hyperoxaluria by liver repopulation with hepatocytes in a mouse model of primary hyperoxaluria type-1.

Jiang J, Salido EC, Guha C, Wang X, Moitra R, Liu L, Roy-Chowdhury J, Roy-Chowdhury N.

Transplantation. 2008 May 15;85(9):1253-60. doi: 10.1097/TP.0b013e31816de49e.

PMID:
18475180
20.

Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat.

Kawashita Y, Guha C, Moitra R, Wang X, Fox IJ, Roy-Chowdhury J, Roy-Chowdhury N.

J Hepatol. 2008 Jul;49(1):99-106. doi: 10.1016/j.jhep.2008.02.020. Epub 2008 Apr 9.

PMID:
18466997
21.

Prevention of hepatocyte allograft rejection in rats by transferring adenoviral early region 3 genes into donor cells.

Mashalova EV, Guha C, Roy-Chowdhury N, Liu L, Fox IJ, Roy-Chowdhury J, Horwitz MS.

Hepatology. 2007 Mar;45(3):755-66.

PMID:
17326202
22.

Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer.

Salido EC, Li XM, Lu Y, Wang X, Santana A, Roy-Chowdhury N, Torres A, Shapiro LJ, Roy-Chowdhury J.

Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18249-54. Epub 2006 Nov 16.

23.

Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice.

Landis CS, Yamanouchi K, Zhou H, Mohan S, Roy-Chowdhury N, Shafritz DA, Koretsky A, Roy-Chowdhury J, Hetherington HP, Guha C.

Hepatology. 2006 Nov;44(5):1250-8.

PMID:
17058269
24.

Role of cysteine residues in the function of human UDP glucuronosyltransferase isoform 1A1 (UGT1A1).

Ghosh SS, Lu Y, Lee SW, Wang X, Guha C, Roy-Chowdhury J, Roy-Chowdhury N.

Biochem J. 2005 Dec 15;392(Pt 3):685-92.

25.

Feasibility of hepatocyte transplantation-based therapies for primary hyperoxalurias.

Guha C, Yamanouchi K, Jiang J, Wang X, Roy Chowdhury N, Santana A, Shapiro LJ, Salido E, Roy-Chowdhury J.

Am J Nephrol. 2005 Mar-Apr;25(2):161-70. Epub 2005 Apr 21.

PMID:
15849463
26.

Cell culture and animal models of viral hepatitis. Part I: hepatitis B.

Guha C, Mohan S, Roy-Chowdhury N, Roy-Chowdhury J.

Lab Anim (NY). 2004 Jul-Aug;33(7):37-46. Review.

PMID:
15224117
27.

Nuclear receptors orchestrate detoxification pathways.

Roy-Chowdhury J, Locker J, Roy-Chowdhury N.

Dev Cell. 2003 May;4(5):607-8.

28.

Molecular therapies for viral hepatitis.

Guha C, Shah SJ, Ghosh SS, Lee SW, Roy-Chowdhury N, Roy-Chowdhury J.

BioDrugs. 2003;17(2):81-91. Review.

PMID:
12641487
29.

A novel strategy for in vivo expansion of transplanted hepatocytes using preparative hepatic irradiation and FasL-induced hepatocellular apoptosis.

Takahashi M, Deb NJ, Kawashita Y, Lee SW, Furgueil J, Okuyama T, Roy-Chowdhury N, Vikram B, Roy-Chowdhury J, Guha C.

Gene Ther. 2003 Feb;10(4):304-13.

PMID:
12595889
30.

Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection.

Guha C, Parashar B, Deb NJ, Garg M, Gorla GR, Singh A, Roy-Chowdhury N, Vikram B, Roy-Chowdhury J.

Hepatology. 2002 Aug;36(2):354-62.

PMID:
12143043
31.

Modification of hepatic genomic DNA using RNA/DNA oligonucleotides.

Kren BT, Chen Z, Felsheim R, Roy Chowdhury N, Roy Chowdhury J, Steer CJ.

Gene Ther. 2002 Jun;9(11):686-90.

32.

Presence of the genetic marker for Gilbert syndrome is associated with increased level and duration of neonatal jaundice.

Roy-Chowdhury N, Deocharan B, Bejjanki HR, Roy-Chowdhury J, Koliopoulos C, Petmezaki S, Valaes T.

Acta Paediatr. 2002;91(1):100-1. No abstract available.

PMID:
11883809
33.

Gene therapy for inherited hyperbilirubinemias.

Roy-Chowdhury N, Kadakol A, Sappal BS, Thummala NR, Ghosh SS, Lee SW, Roy-Chowdhury J.

J Perinatol. 2001 Dec;21 Suppl 1:S114-8; discussion S125-7.

34.

Amplification of engrafted hepatocytes by preparative manipulation of the host liver.

Guha C, Deb NJ, Sappal BS, Ghosh SS, Roy-Chowdhury N, Roy-Chowdhury J.

Artif Organs. 2001 Jul;25(7):522-8. Review.

PMID:
11493272
35.

Hepatocyte-based gene therapy.

Guha C, Roy-Chowdhury N, Jauregui H, Roy-Chowdhury J.

J Hepatobiliary Pancreat Surg. 2001;8(1):51-7. Review.

PMID:
11294290
36.

Liver irradiation: a potential preparative regimen for hepatocyte transplantation.

Guha C, Parashar B, Deb NJ, Sharma A, Gorla GR, Alfieri A, Roy-Chowdhury N, Roy-Chowdhury J, Vikram B.

Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):451-7. Review.

PMID:
11173140
37.

A long-term hepatitis B viremia model generated by transplanting nontumorigenic immortalized human hepatocytes in Rag-2-deficient mice.

Brown JJ, Parashar B, Moshage H, Tanaka KE, Engelhardt D, Rabbani E, Roy-Chowdhury N, Roy-Chowdhury J.

Hepatology. 2000 Jan;31(1):173-81.

PMID:
10613743
38.

Amelioration of radiation-induced liver damage in partially hepatectomized rats by hepatocyte transplantation.

Guha C, Sharma A, Gupta S, Alfieri A, Gorla GR, Gagandeep S, Sokhi R, Roy-Chowdhury N, Tanaka KE, Vikram B, Roy-Chowdhury J.

Cancer Res. 1999 Dec 1;59(23):5871-4.

39.

Long-term amelioration of bilirubin glucuronidation defect in Gunn rats by transplanting genetically modified immortalized autologous hepatocytes.

Tada K, Roy-Chowdhury N, Prasad V, Kim BH, Manchikalapudi P, Fox IJ, van Duijvendijk P, Bosma PJ, Roy-Chowdhury J.

Cell Transplant. 1998 Nov-Dec;7(6):607-16.

PMID:
9853589
40.

Splice-site mutations: a novel genetic mechanism of Crigler-Najjar syndrome type 1.

Gantla S, Bakker CT, Deocharan B, Thummala NR, Zweiner J, Sinaasappel M, Roy Chowdhury J, Bosma PJ, Roy Chowdhury N.

Am J Hum Genet. 1998 Mar;62(3):585-92.

41.

Mechanisms of intrathymic tolerance induction to isolated rat hepatocyte allografts.

Attavar P, Budhai L, Kim BH, Roy-Chowdhury N, Roy-Chowdhury J, Davidson A.

Hepatology. 1997 Nov;26(5):1287-95.

PMID:
9362374
42.

Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat.

Ilan Y, Jona VK, Sengupta K, Davidson A, Horwitz MS, Roy-Chowdhury N, Roy-Chowdhury J.

Hepatology. 1997 Oct;26(4):949-56.

PMID:
9328318
43.

Massive repopulation of rat liver by transplantation of hepatocytes into specific lobes of the liver and ligation of portal vein branches to other lobes.

Ilan Y, Roy-Chowdhury N, Prakash R, Jona V, Attavar P, Guha C, Tada K, Roy-Chowdhury J.

Transplantation. 1997 Jul 15;64(1):8-13.

PMID:
9233693
44.

Cell and gene therapy for inherited deficiency of bilirubin glucuronidation.

Kim BH, Takahashi M, Tada K, Bosma PJ, Roy-Chowdhury J, Roy-Chowdhury N.

J Perinatol. 1996 May-Jun;16(3 Pt 2):S67-72. Review. No abstract available.

PMID:
8817442
45.

Bilirubin glucuronidation by intact Gunn rat fibroblasts expressing bilirubin UDP-glucuronosyltransferase.

Seppen J, Tada K, Hellwig S, Bakker CT, Prasad VR, Roy Chowdhury N, Roy Chowdhury J, Bosma PJ, Oude Elferink RP.

Biochem J. 1996 Mar 1;314 ( Pt 2):477-83.

47.

Hepatic uptake of bilirubin diglucuronide: analysis by using sinusoidal plasma membrane vesicles.

Adachi Y, Roy-Chowdhury J, Roy-Chowdhury N, Kinne R, Tran T, Kobayashi H, Arias IM.

J Biochem. 1990 May;107(5):749-54.

48.

Human liver cell transplantation. Prolonged function in athymic-Gunn and athymic-analbuminemic hybrid rats.

Moscioni AD, Roy-Chowdhury J, Barbour R, Brown LL, Roy-Chowdhury N, Competiello LS, Lahiri P, Demetriou AA.

Gastroenterology. 1989 Jun;96(6):1546-51.

PMID:
2653943
49.

Isolation of multiple normal and functionally defective forms of uridine diphosphate-glucuronosyltransferase from inbred Gunn rats.

Roy Chowdhury N, Gross F, Moscioni AD, Kram M, Arias IM, Roy Chowdhury J.

J Clin Invest. 1987 Feb;79(2):327-34.

50.

Isolation and characterization of multiple forms of rat liver UDP-glucuronate glucuronosyltransferase.

Roy Chowdhury J, Roy Chowdhury N, Falany CN, Tephly TR, Arias IM.

Biochem J. 1986 Feb 1;233(3):827-37.

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