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Items: 1 to 50 of 75

1.

Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis.

Barahman M, Zhang W, Harris HY, Aiyer A, Kabarriti R, Kinkhabwala M, Roy-Chowdhury N, Beck AP, Scanlan TS, Roy-Chowdhury J, Asp P, Guha C.

J Hepatol. 2019 Jun;70(6):1170-1179. doi: 10.1016/j.jhep.2019.01.010. Epub 2019 Jan 14.

PMID:
30654068
2.

Genes and Pathways Promoting Long-Term Liver Repopulation by Ex Vivo hYAP-ERT2 Transduced Hepatocytes and Treatment of Jaundice in Gunn Rats.

Peterson EA, Polgar Z, Devakanmalai GS, Li Y, Jaber FL, Zhang W, Wang X, Iqbal NJ, Murray JW, Roy-Chowdhury N, Quispe-Tintaya W, Maslov AY, Tchaikovskaya TL, Sharma Y, Rogler LE, Gupta S, Zhu L, Roy-Chowdhury J, Shafritz DA.

Hepatol Commun. 2018 Nov 20;3(1):129-146. doi: 10.1002/hep4.1278. eCollection 2019 Jan.

3.

Hepatocyte Transplantation: Quo Vadis?

Barahman M, Asp P, Roy-Chowdhury N, Kinkhabwala M, Roy-Chowdhury J, Kabarriti R, Guha C.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):922-934. doi: 10.1016/j.ijrobp.2018.11.016. Epub 2018 Nov 29. Review.

PMID:
30503786
4.

Drug- and Drug Abuse-Associated Hyperbilirubinemia: Experience With Atazanavir.

Roy-Chowdhury J, Roy-Chowdhury N, Listowsky I, Wolkoff AW.

Clin Pharmacol Drug Dev. 2017 Mar;6(2):140-146. doi: 10.1002/cpdd.314.

5.

Host conditioning and rejection monitoring in hepatocyte transplantation in humans.

Soltys KA, Setoyama K, Tafaleng EN, Soto Gutiérrez A, Fong J, Fukumitsu K, Nishikawa T, Nagaya M, Sada R, Haberman K, Gramignoli R, Dorko K, Tahan V, Dreyzin A, Baskin K, Crowley JJ, Quader MA, Deutsch M, Ashokkumar C, Shneider BL, Squires RH, Ranganathan S, Reyes-Mugica M, Dobrowolski SF, Mazariegos G, Elango R, Stolz DB, Strom SC, Vockley G, Roy-Chowdhury J, Cascalho M, Guha C, Sindhi R, Platt JL, Fox IJ.

J Hepatol. 2017 May;66(5):987-1000. doi: 10.1016/j.jhep.2016.12.017. Epub 2016 Dec 24.

6.

Gunn Rats as a Surrogate Model for Evaluation of Hepatocyte Transplantation-Based Therapies of Crigler-Najjar Syndrome Type 1.

Polgar Z, Li Y, Li Wang X, Guha C, Roy-Chowdhury N, Roy-Chowdhury J.

Methods Mol Biol. 2017;1506:131-147.

PMID:
27830550
7.

Oxalobacter formigenes-Derived Bioactive Factors Stimulate Oxalate Transport by Intestinal Epithelial Cells.

Arvans D, Jung YC, Antonopoulos D, Koval J, Granja I, Bashir M, Karrar E, Roy-Chowdhury J, Musch M, Asplin J, Chang E, Hassan H.

J Am Soc Nephrol. 2017 Mar;28(3):876-887. doi: 10.1681/ASN.2016020132. Epub 2016 Oct 13.

8.

Hepatocyte-like cells derived from induced pluripotent stem cells.

Roy-Chowdhury N, Wang X, Guha C, Roy-Chowdhury J.

Hepatol Int. 2017 Jan;11(1):54-69. doi: 10.1007/s12072-016-9757-y. Epub 2016 Aug 17. Review.

PMID:
27530815
9.

Human Urinary Epithelial Cells as a Source of Engraftable Hepatocyte-Like Cells Using Stem Cell Technology.

Sauer V, Tchaikovskaya T, Wang X, Li Y, Zhang W, Tar K, Polgar Z, Ding J, Guha C, Fox IJ, Roy-Chowdhury N, Roy-Chowdhury J.

Cell Transplant. 2016 Dec 13;25(12):2221-2243. doi: 10.3727/096368916X692014. Epub 2016 Jun 9.

PMID:
27512979
10.

Gene therapy of Wilson disease: A "golden" opportunity using rAAV on the 50th anniversary of the discovery of the virus.

Roy-Chowdhury J, Schilsky ML.

J Hepatol. 2016 Feb;64(2):265-267. doi: 10.1016/j.jhep.2015.11.017. Epub 2015 Nov 27. No abstract available.

PMID:
26639392
11.

Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes.

Chen Y, Li Y, Wang X, Zhang W, Sauer V, Chang CJ, Han B, Tchaikovskaya T, Avsar Y, Tafaleng E, Madhusudana Girija S, Tar K, Polgar Z, Strom S, Bouhassira EE, Guha C, Fox IJ, Roy-Chowdhury J, Roy-Chowdhury N.

Stem Cell Reports. 2015 Jul 14;5(1):22-30. doi: 10.1016/j.stemcr.2015.04.017. Epub 2015 Jun 11.

12.

Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.

Tafaleng EN, Chakraborty S, Han B, Hale P, Wu W, Soto-Gutierrez A, Feghali-Bostwick CA, Wilson AA, Kotton DN, Nagaya M, Strom SC, Roy-Chowdhury J, Stolz DB, Perlmutter DH, Fox IJ.

Hepatology. 2015 Jul;62(1):147-57. doi: 10.1002/hep.27753. Epub 2015 Apr 13.

13.

Induced pluripotent stem cells as a source of hepatocytes.

Sauer V, Roy-Chowdhury N, Guha C, Roy-Chowdhury J.

Curr Pathobiol Rep. 2014 Mar;2(1):11-20.

14.

An autologous in situ tumor vaccination approach for hepatocellular carcinoma. 2. Tumor-specific immunity and cure after radio-inducible suicide gene therapy and systemic CD40-ligand and Flt3-ligand gene therapy in an orthotopic tumor model.

Kawashita Y, Deb NJ, Garg MK, Kabarriti R, Fan Z, Alfieri AA, Roy-Chowdhury J, Guha C.

Radiat Res. 2014 Aug;182(2):201-10. doi: 10.1667/RR13617.1. Epub 2014 Jul 3.

PMID:
24992166
15.

An autologous in situ tumor vaccination approach for hepatocellular carcinoma. 1. Flt3 ligand gene transfer increases antitumor effects of a radio-inducible suicide gene therapy in an ectopic tumor model.

Kawashita Y, Deb NJ, Garg M, Kabarriti R, Alfieri A, Takahashi M, Roy-Chowdhury J, Guha C.

Radiat Res. 2014 Aug;182(2):191-200. doi: 10.1667/RR13594.1. Epub 2014 Jun 27.

PMID:
24972258
16.

Bone marrow-derived stromal cell therapy in cirrhosis: clinical evidence, cellular mechanisms, and implications for the treatment of hepatocellular carcinoma.

Vainshtein JM, Kabarriti R, Mehta KJ, Roy-Chowdhury J, Guha C.

Int J Radiat Oncol Biol Phys. 2014 Jul 15;89(4):786-803. doi: 10.1016/j.ijrobp.2014.02.017.

17.

A nonhuman primate model of human radiation-induced venocclusive liver disease and hepatocyte injury.

Yannam GR, Han B, Setoyama K, Yamamoto T, Ito R, Brooks JM, Guzman-Lepe J, Galambos C, Fong JV, Deutsch M, Quader MA, Yamanouchi K, Kabarriti R, Mehta K, Soto-Gutierrez A, Roy-Chowdhury J, Locker J, Abe M, Enke CA, Baranowska-Kortylewicz J, Solberg TD, Guha C, Fox IJ.

Int J Radiat Oncol Biol Phys. 2014 Feb 1;88(2):404-411. doi: 10.1016/j.ijrobp.2013.10.037. Epub 2013 Dec 5.

18.

Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage-hair hypoplasia.

Rogler LE, Kosmyna B, Moskowitz D, Bebawee R, Rahimzadeh J, Kutchko K, Laederach A, Notarangelo LD, Giliani S, Bouhassira E, Frenette P, Roy-Chowdhury J, Rogler CE.

Hum Mol Genet. 2014 Jan 15;23(2):368-82. doi: 10.1093/hmg/ddt427. Epub 2013 Sep 5.

19.

Single liver lobe repopulation with wildtype hepatocytes using regional hepatic irradiation cures jaundice in Gunn rats.

Zhou H, Dong X, Kabarriti R, Chen Y, Avsar Y, Wang X, Ding J, Liu L, Fox IJ, Roy-Chowdhury J, Roy-Chowdhury N, Guha C.

PLoS One. 2012;7(10):e46775. doi: 10.1371/journal.pone.0046775. Epub 2012 Oct 16.

20.

Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes.

Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, Wong RJ, Avsar Y, Guha C, Perlmutter DH, Fox IJ, Roy-Chowdhury J.

J Clin Invest. 2011 May;121(5):1930-4. doi: 10.1172/JCI45260. Epub 2011 Apr 18.

21.

Improving the techniques for human hepatocyte transplantation: report from a consensus meeting in London.

Puppi J, Strom SC, Hughes RD, Bansal S, Castell JV, Dagher I, Ellis EC, Nowak G, Ericzon BG, Fox IJ, Gómez-Lechón MJ, Guha C, Gupta S, Mitry RR, Ohashi K, Ott M, Reid LM, Roy-Chowdhury J, Sokal E, Weber A, Dhawan A.

Cell Transplant. 2012;21(1):1-10. doi: 10.3727/096368911X566208.

PMID:
21457616
22.

Modeling and therapy of human liver diseases using induced pluripotent stem cells: how far have we come?

Soto-Gutierrez A, Tafaleng E, Kelly V, Roy-Chowdhury J, Fox IJ.

Hepatology. 2011 Feb;53(2):708-11. doi: 10.1002/hep.24143. No abstract available.

23.

Hepatic differentiation of liver-derived progenitor cells and their characterization by microRNA analysis.

Chen Y, Zhou H, Sarver AL, Zeng Y, Roy-Chowdhury J, Steer CJ, Sahin MB.

Liver Transpl. 2010 Sep;16(9):1086-97. doi: 10.1002/lt.22111.

24.

Barriers to the successful treatment of liver disease by hepatocyte transplantation.

Soltys KA, Soto-Gutiérrez A, Nagaya M, Baskin KM, Deutsch M, Ito R, Shneider BL, Squires R, Vockley J, Guha C, Roy-Chowdhury J, Strom SC, Platt JL, Fox IJ.

J Hepatol. 2010 Oct;53(4):769-74. doi: 10.1016/j.jhep.2010.05.010. Epub 2010 Jun 30. No abstract available.

25.

Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice.

Bhanja P, Saha S, Kabarriti R, Liu L, Roy-Chowdhury N, Roy-Chowdhury J, Sellers RS, Alfieri AA, Guha C.

PLoS One. 2009 Nov 24;4(11):e8014. doi: 10.1371/journal.pone.0008014.

26.

Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon.

Wang X, Sarkar DP, Mani P, Steer CJ, Chen Y, Guha C, Chandrasekhar V, Chaudhuri A, Roy-Chowdhury N, Kren BT, Roy-Chowdhury J.

Hepatology. 2009 Sep;50(3):815-24. doi: 10.1002/hep.23060.

27.

Ex vivo gene transfer into hepatocytes.

Wang X, Mani P, Sarkar DP, Roy-Chowdhury N, Roy-Chowdhury J.

Methods Mol Biol. 2009;481:117-40. doi: 10.1007/978-1-59745-201-4_11. Review.

PMID:
19096805
28.

Differentiation and transplantation of human embryonic stem cell-derived hepatocytes.

Basma H, Soto-Gutiérrez A, Yannam GR, Liu L, Ito R, Yamamoto T, Ellis E, Carson SD, Sato S, Chen Y, Muirhead D, Navarro-Alvarez N, Wong RJ, Roy-Chowdhury J, Platt JL, Mercer DF, Miller JD, Strom SC, Kobayashi N, Fox IJ.

Gastroenterology. 2009 Mar;136(3):990-9. doi: 10.1053/j.gastro.2008.10.047. Epub 2008 Oct 29.

29.

Hepatic irradiation augments engraftment of donor cells following hepatocyte transplantation.

Yamanouchi K, Zhou H, Roy-Chowdhury N, Macaluso F, Liu L, Yamamoto T, Yannam GR, Enke C, Solberg TD, Adelson AB, Platt JL, Fox IJ, Roy-Chowdhury J, Guha C.

Hepatology. 2009 Jan;49(1):258-67. doi: 10.1002/hep.22573.

30.

Correction of hyperoxaluria by liver repopulation with hepatocytes in a mouse model of primary hyperoxaluria type-1.

Jiang J, Salido EC, Guha C, Wang X, Moitra R, Liu L, Roy-Chowdhury J, Roy-Chowdhury N.

Transplantation. 2008 May 15;85(9):1253-60. doi: 10.1097/TP.0b013e31816de49e.

PMID:
18475180
31.

Hepatic repopulation with stably transduced conditionally immortalized hepatocytes in the Gunn rat.

Kawashita Y, Guha C, Moitra R, Wang X, Fox IJ, Roy-Chowdhury J, Roy-Chowdhury N.

J Hepatol. 2008 Jul;49(1):99-106. doi: 10.1016/j.jhep.2008.02.020. Epub 2008 Apr 9.

PMID:
18466997
32.

Prevention of hepatocyte allograft rejection in rats by transferring adenoviral early region 3 genes into donor cells.

Mashalova EV, Guha C, Roy-Chowdhury N, Liu L, Fox IJ, Roy-Chowdhury J, Horwitz MS.

Hepatology. 2007 Mar;45(3):755-66.

PMID:
17326202
33.

Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer.

Salido EC, Li XM, Lu Y, Wang X, Santana A, Roy-Chowdhury N, Torres A, Shapiro LJ, Roy-Chowdhury J.

Proc Natl Acad Sci U S A. 2006 Nov 28;103(48):18249-54. Epub 2006 Nov 16.

34.

Noninvasive evaluation of liver repopulation by transplanted hepatocytes using 31P MRS imaging in mice.

Landis CS, Yamanouchi K, Zhou H, Mohan S, Roy-Chowdhury N, Shafritz DA, Koretsky A, Roy-Chowdhury J, Hetherington HP, Guha C.

Hepatology. 2006 Nov;44(5):1250-8.

PMID:
17058269
35.

Role of cysteine residues in the function of human UDP glucuronosyltransferase isoform 1A1 (UGT1A1).

Ghosh SS, Lu Y, Lee SW, Wang X, Guha C, Roy-Chowdhury J, Roy-Chowdhury N.

Biochem J. 2005 Dec 15;392(Pt 3):685-92.

36.

Feasibility of hepatocyte transplantation-based therapies for primary hyperoxalurias.

Guha C, Yamanouchi K, Jiang J, Wang X, Roy Chowdhury N, Santana A, Shapiro LJ, Salido E, Roy-Chowdhury J.

Am J Nephrol. 2005 Mar-Apr;25(2):161-70. Epub 2005 Apr 21.

PMID:
15849463
37.

Multicenter clinical trials on a novel polyherbal formulation in allergic rhinitis.

Saxena VS, Venkateshwarlu K, Nadig P, Barbhaiya HC, Bhatia N, Borkar DM, Gill RS, Jain RK, Katiyar SK, Nagendra Prasad KV, Nalinesha KM, Nasiruddin K, Rishi JP, Roy Chowdhury J, Saharia PS, Thomas B, Bagchi D.

Int J Clin Pharmacol Res. 2004;24(2-3):79-94.

PMID:
15689054
38.

Hepatocyte transplantation: state of the art and strategies for overcoming existing hurdles.

Lee SW, Wang X, Chowdhury NR, Roy-Chowdhury J.

Ann Hepatol. 2004 Apr-Jun;3(2):48-53. Review.

39.

Cell culture and animal models of viral hepatitis. Part I: hepatitis B.

Guha C, Mohan S, Roy-Chowdhury N, Roy-Chowdhury J.

Lab Anim (NY). 2004 Jul-Aug;33(7):37-46. Review.

PMID:
15224117
40.

Hepatocyte transplantation.

Fox IJ, Roy-Chowdhury J.

J Hepatol. 2004 Jun;40(6):878-86. Review. No abstract available.

PMID:
15158325
41.
42.

Nuclear receptors orchestrate detoxification pathways.

Roy-Chowdhury J, Locker J, Roy-Chowdhury N.

Dev Cell. 2003 May;4(5):607-8.

43.

Molecular therapies for viral hepatitis.

Guha C, Shah SJ, Ghosh SS, Lee SW, Roy-Chowdhury N, Roy-Chowdhury J.

BioDrugs. 2003;17(2):81-91. Review.

PMID:
12641487
44.

A novel strategy for in vivo expansion of transplanted hepatocytes using preparative hepatic irradiation and FasL-induced hepatocellular apoptosis.

Takahashi M, Deb NJ, Kawashita Y, Lee SW, Furgueil J, Okuyama T, Roy-Chowdhury N, Vikram B, Roy-Chowdhury J, Guha C.

Gene Ther. 2003 Feb;10(4):304-13.

PMID:
12595889
45.

Normal hepatocytes correct serum bilirubin after repopulation of Gunn rat liver subjected to irradiation/partial resection.

Guha C, Parashar B, Deb NJ, Garg M, Gorla GR, Singh A, Roy-Chowdhury N, Vikram B, Roy-Chowdhury J.

Hepatology. 2002 Aug;36(2):354-62.

PMID:
12143043
46.

Modification of hepatic genomic DNA using RNA/DNA oligonucleotides.

Kren BT, Chen Z, Felsheim R, Roy Chowdhury N, Roy Chowdhury J, Steer CJ.

Gene Ther. 2002 Jun;9(11):686-90.

47.

Evolution of adenoviruses as gene therapy vectors.

Roy-Chowdhury J, Horwitz MS.

Mol Ther. 2002 Apr;5(4):340-4. No abstract available.

48.

Presence of the genetic marker for Gilbert syndrome is associated with increased level and duration of neonatal jaundice.

Roy-Chowdhury N, Deocharan B, Bejjanki HR, Roy-Chowdhury J, Koliopoulos C, Petmezaki S, Valaes T.

Acta Paediatr. 2002;91(1):100-1. No abstract available.

PMID:
11883809
49.

Gene therapy for inherited hyperbilirubinemias.

Roy-Chowdhury N, Kadakol A, Sappal BS, Thummala NR, Ghosh SS, Lee SW, Roy-Chowdhury J.

J Perinatol. 2001 Dec;21 Suppl 1:S114-8; discussion S125-7.

50.

Amplification of engrafted hepatocytes by preparative manipulation of the host liver.

Guha C, Deb NJ, Sappal BS, Ghosh SS, Roy-Chowdhury N, Roy-Chowdhury J.

Artif Organs. 2001 Jul;25(7):522-8. Review.

PMID:
11493272

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