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Items: 38

1.

Oncogene-Selective Sensitivity to Synchronous Cell Death following Modulation of the Amino Acid Nutrient Cystine.

Poursaitidis I, Wang X, Crighton T, Labuschagne C, Mason D, Cramer SL, Triplett K, Roy R, Pardo OE, Seckl MJ, Rowlinson SW, Stone E, Lamb RF.

Cell Rep. 2017 Mar 14;18(11):2547-2556. doi: 10.1016/j.celrep.2017.02.054.

2.

Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.

Burrage LC, Sun Q, Elsea SH, Jiang MM, Nagamani SC, Frankel AE, Stone E, Alters SE, Johnson DE, Rowlinson SW, Georgiou G; Members of Urea Cycle Disorders Consortium, Lee BH.

Hum Mol Genet. 2015 Nov 15;24(22):6417-27. doi: 10.1093/hmg/ddv352. Epub 2015 Sep 10.

3.

Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2.

Blobaum AL, Xu S, Rowlinson SW, Duggan KC, Banerjee S, Kudalkar SN, Birmingham WR, Ghebreselasie K, Marnett LJ.

J Biol Chem. 2015 May 15;290(20):12793-803. doi: 10.1074/jbc.M114.635987. Epub 2015 Mar 30.

4.

A BMP7 variant inhibits the tumorigenic potential of glioblastoma stem-like cells.

Tate CM, Pallini R, Ricci-Vitiani L, Dowless M, Shiyanova T, D'Alessandris GQ, Morgante L, Giannetti S, Larocca LM, di Martino S, Rowlinson SW, De Maria R, Stancato L.

Cell Death Differ. 2012 Oct;19(10):1644-54. doi: 10.1038/cdd.2012.44. Epub 2012 Apr 27.

5.

An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway.

Rowlinson SW, Yoshizato H, Barclay JL, Brooks AJ, Behncken SN, Kerr LM, Millard K, Palethorpe K, Nielsen K, Clyde-Smith J, Hancock JF, Waters MJ.

Nat Cell Biol. 2008 Jun;10(6):740-7. doi: 10.1038/ncb1737. Epub 2008 May 18. Erratum in: Nat Cell Biol. 2008 Jul;10(7):874.

PMID:
18488018
6.

Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4.

Hu SH, Gee CL, Latham CF, Rowlinson SW, Rova U, Jones A, Halliday JA, Bryant NJ, James DE, Martin JL.

Protein Expr Purif. 2003 Oct;31(2):305-10.

PMID:
14550652
7.

A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385.

Rowlinson SW, Kiefer JR, Prusakiewicz JJ, Pawlitz JL, Kozak KR, Kalgutkar AS, Stallings WC, Kurumbail RG, Marnett LJ.

J Biol Chem. 2003 Nov 14;278(46):45763-9. Epub 2003 Aug 18.

8.

Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid anandamide.

Kozak KR, Prusakiewicz JJ, Rowlinson SW, Prudhomme DR, Marnett LJ.

Biochemistry. 2003 Aug 5;42(30):9041-9.

PMID:
12885237
9.

Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.

Liu L, Ding C, Zeng W, Heuer JG, Tetreault JW, Noblitt TW, Hangoc G, Cooper S, Brune KA, Sharma G, Fox N, Rowlinson SW, Rogers DP, Witcher DR, Lambooy PK, Wroblewski VJ, Miller JR, Broxmeyer HE.

Blood. 2003 Nov 1;102(9):3206-9. Epub 2003 Jul 10.

10.

Functional analysis of the molecular determinants of cyclooxygenase-2 acetylation by 2-acetoxyphenylhept-2-ynyl sulfide.

Phillip Hochgesang G, Nemeth-Cawley JF, Rowlinson SW, Caprioli RM, Marnett LJ.

Arch Biochem Biophys. 2003 Jan 1;409(1):127-33.

PMID:
12464251
11.

A novel bioassay for human somatogenic activity in serum samples supports the clinical reliability of immunoassays.

Rowland JE, Marshall NJ, Leung KC, Ho KK, Cotterill AM, Rowlinson SW, Waters MJ.

Clin Endocrinol (Oxf). 2002 Apr;56(4):475-85.

PMID:
11966740
12.

Enantiospecific, selective cyclooxygenase-2 inhibitors.

Kozak KR, Prusakiewicz JJ, Rowlinson SW, Marnett LJ.

Bioorg Med Chem Lett. 2002 May 6;12(9):1315-8.

PMID:
11965379
13.

Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors.

Kalgutkar AS, Rowlinson SW, Crews BC, Marnett LJ.

Bioorg Med Chem Lett. 2002 Feb 25;12(4):521-4.

PMID:
11844663
14.

Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. A critical role for serine 530 and valine 349.

Schneider C, Boeglin WE, Prusakiewicz JJ, Rowlinson SW, Marnett LJ, Samel N, Brash AR.

J Biol Chem. 2002 Jan 4;277(1):478-85. Epub 2001 Oct 24. Erratum in: J Biol Chem 2002 Apr 12;277(15):13354.

15.

Amino acid determinants in cyclooxygenase-2 oxygenation of the endocannabinoid 2-arachidonylglycerol.

Kozak KR, Prusakiewicz JJ, Rowlinson SW, Schneider C, Marnett LJ.

J Biol Chem. 2001 Aug 10;276(32):30072-7. Epub 2001 Jun 11.

16.

Characterization of the lysyl adducts of prostaglandin H-synthases that are derived from oxygenation of arachidonic acid.

Boutaud O, Brame CJ, Chaurand P, Li J, Rowlinson SW, Crews BC, Ji C, Marnett LJ, Caprioli RM, Roberts LJ 2nd, Oates JA.

Biochemistry. 2001 Jun 12;40(23):6948-55.

PMID:
11389610
17.

Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2.

Kozak KR, Rowlinson SW, Marnett LJ.

J Biol Chem. 2000 Oct 27;275(43):33744-9.

19.

Structural insights into the stereochemistry of the cyclooxygenase reaction.

Kiefer JR, Pawlitz JL, Moreland KT, Stegeman RA, Hood WF, Gierse JK, Stevens AM, Goodwin DC, Rowlinson SW, Marnett LJ, Stallings WC, Kurumbail RG.

Nature. 2000 May 4;405(6782):97-101.

PMID:
10811226
20.
21.

Discovery of a new class of selective cyclooxygenase-2 (COX-2) inhibitor that covalently modifies the isozyme.

Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Marnett LJ.

Adv Exp Med Biol. 1999;469:139-43. No abstract available.

PMID:
10667322
22.

Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors.

Kalgutkar AS, Crews BC, Rowlinson SW, Marnett AB, Kozak KR, Remmel RP, Marnett LJ.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):925-30.

24.

Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition.

Marnett LJ, Rowlinson SW, Goodwin DC, Kalgutkar AS, Lanzo CA.

J Biol Chem. 1999 Aug 13;274(33):22903-6. Review. No abstract available.

26.

Aspirin-like molecules that covalently inactivate cyclooxygenase-2.

Kalgutkar AS, Crews BC, Rowlinson SW, Garner C, Seibert K, Marnett LJ.

Science. 1998 May 22;280(5367):1268-70.

27.

Activation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies. A specific conformational change may be required for full-length receptor signaling.

Rowlinson SW, Behncken SN, Rowland JE, Clarkson RW, Strasburger CJ, Wu Z, Baumbach W, Waters MJ.

J Biol Chem. 1998 Feb 27;273(9):5307-14.

28.

Aspartate 171 is the major primate-specific determinant of human growth hormone. Engineering porcine growth hormone to activate the human receptor.

Behncken SN, Rowlinson SW, Rowland JE, Conway-Campbell BL, Monks TA, Waters MJ.

J Biol Chem. 1997 Oct 24;272(43):27077-83.

29.

Large-scale preparation and characterization of recombinant ovine placental lactogen.

Sakal E, Bignon C, Grosclaude J, Kantor A, Shapira R, Leibovitch H, Helman D, Nespoulous C, Shamay A, Rowlinson SW, Djiane J, Gertler A.

J Endocrinol. 1997 Feb;152(2):317-27.

PMID:
9071989
30.
31.

A growth hormone agonist produced by targeted mutagenesis at binding site 1. Evidence that site 1 regulates bioactivity.

Rowlinson SW, Barnard R, Bastiras S, Robins AJ, Brinkworth R, Waters MJ.

J Biol Chem. 1995 Jul 14;270(28):16833-9.

32.

Serum growth hormone binding protein and hepatic GH binding sites in the Lewis dwarf rat: effects of IGF-I and GH.

Barnard R, Mulcahy J, García-Aragón J, Wyse B, Owens PC, Rowlinson SW, Talamantes F, Baumbach WR, Waters MJ.

Growth Regul. 1994 Dec;4(4):147-54.

PMID:
7756972
33.
34.

Signal transduction by the growth hormone receptor.

Waters MJ, Rowlinson SW, Clarkson RW, Chen CM, Lobie PE, Norstedt G, Mertani H, Morel G, Brinkworth R, Wells CA, et al.

Proc Soc Exp Biol Med. 1994 Jul;206(3):216-20. Review.

PMID:
8016156
35.

The search for receptor-interactive regions in growth hormone: historical perspectives and novel strategies.

Barnard R, Rowlinson SW, Brinkworth R, Bastiras S, Robins A, Wells JR, Waters MJ.

Acta Paediatr Suppl. 1994 Apr;399:33-41. Review. No abstract available.

PMID:
7949615
36.

The first disulphide loop of the rabbit growth hormone receptor is required for binding to the hormone.

Gobius KS, Rowlinson SW, Barnard R, Mattick JS, Waters MJ.

J Mol Endocrinol. 1992 Dec;9(3):213-20.

PMID:
1476608
38.

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