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Items: 1 to 50 of 415

1.

No chromosome arm unturned: in memory of Roland Berger 1934-2012.

Harrison CJ, Rowley JD, Van den Berghe H, Bernheim A, Martineau M, Gautier M, Le Coniat-Busson M, Romana S, Dastugue N, Hagemeijer A, Jonveaux P, Nguyen-Khac F, Bernard OA.

Leukemia. 2014 Feb;28(2):464-9: discussion 469. doi: 10.1038/leu.2013.340. No abstract available.

PMID:
24496283
2.

TET1 plays an essential oncogenic role in MLL-rearranged leukemia.

Huang H, Jiang X, Li Z, Li Y, Song CX, He C, Sun M, Chen P, Gurbuxani S, Wang J, Hong GM, Elkahloun AG, Arnovitz S, Wang J, Szulwach K, Lin L, Street C, Wunderlich M, Dawlaty M, Neilly MB, Jaenisch R, Yang FC, Mulloy JC, Jin P, Liu PP, Rowley JD, Xu M, He C, Chen J.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11994-9. doi: 10.1073/pnas.1310656110. Epub 2013 Jul 1.

3.

miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.

Chen P, Price C, Li Z, Li Y, Cao D, Wiley A, He C, Gurbuxani S, Kunjamma RB, Huang H, Jiang X, Arnovitz S, Xu M, Hong GM, Elkahloun AG, Neilly MB, Wunderlich M, Larson RA, Le Beau MM, Mulloy JC, Liu PP, Rowley JD, Chen J.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11511-6. doi: 10.1073/pnas.1310144110. Epub 2013 Jun 24.

4.

Genetics. A story of swapped ends.

Rowley JD.

Science. 2013 Jun 21;340(6139):1412-3. doi: 10.1126/science.1241318. No abstract available.

PMID:
23788787
5.

Critical role of miR-9 in myelopoiesis and EVI1-induced leukemogenesis.

Senyuk V, Zhang Y, Liu Y, Ming M, Premanand K, Zhou L, Chen P, Chen J, Rowley JD, Nucifora G, Qian Z.

Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5594-9. doi: 10.1073/pnas.1302645110. Epub 2013 Mar 18.

6.

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.

Li Z, Herold T, He C, Valk PJ, Chen P, Jurinovic V, Mansmann U, Radmacher MD, Maharry KS, Sun M, Yang X, Huang H, Jiang X, Sauerland MC, Büchner T, Hiddemann W, Elkahloun A, Neilly MB, Zhang Y, Larson RA, Le Beau MM, Caligiuri MA, Döhner K, Bullinger L, Liu PP, Delwel R, Marcucci G, Lowenberg B, Bloomfield CD, Rowley JD, Bohlander SK, Chen J.

J Clin Oncol. 2013 Mar 20;31(9):1172-81. doi: 10.1200/JCO.2012.44.3184. Epub 2013 Feb 4.

7.

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

Li Z, Zhang Z, Li Y, Arnovitz S, Chen P, Huang H, Jiang X, Hong GM, Kunjamma RB, Ren H, He C, Wang CZ, Elkahloun AG, Valk PJ, Döhner K, Neilly MB, Bullinger L, Delwel R, Löwenberg B, Liu PP, Morgan R, Rowley JD, Yuan CS, Chen J.

Blood. 2013 Feb 21;121(8):1422-31. doi: 10.1182/blood-2012-07-442004. Epub 2012 Dec 20.

8.

New fusion transcripts identified in normal karyotype acute myeloid leukemia.

Wen H, Li Y, Malek SN, Kim YC, Xu J, Chen P, Xiao F, Huang X, Zhou X, Xuan Z, Mankala S, Hou G, Rowley JD, Zhang MQ, Wang SM.

PLoS One. 2012;7(12):e51203. doi: 10.1371/journal.pone.0051203. Epub 2012 Dec 12.

9.

MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.

Jiang X, Huang H, Li Z, He C, Li Y, Chen P, Gurbuxani S, Arnovitz S, Hong GM, Price C, Ren H, Kunjamma RB, Neilly MB, Salat J, Wunderlich M, Slany RK, Zhang Y, Larson RA, Le Beau MM, Mulloy JC, Rowley JD, Chen J.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19397-402. doi: 10.1073/pnas.1217519109. Epub 2012 Nov 6.

10.

Two isoforms of HOXA9 function differently but work synergistically in human MLL-rearranged leukemia.

He M, Chen P, Arnovitz S, Li Y, Huang H, Neilly MB, Wei M, Rowley JD, Chen J, Li Z.

Blood Cells Mol Dis. 2012 Aug 15;49(2):102-6. doi: 10.1016/j.bcmd.2012.05.003. Epub 2012 May 25.

11.

Broadband terahertz pulse emission from ZnGeP2.

Rowley JD, Pierce JK, Brant AT, Halliburton LE, Giles NC, Schunemann PG, Bristow AD.

Opt Lett. 2012 Mar 1;37(5):788-90. doi: 10.1364/OL.37.000788.

PMID:
22378394
12.

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML.

Li Z, Huang H, Li Y, Jiang X, Chen P, Arnovitz S, Radmacher MD, Maharry K, Elkahloun A, Yang X, He C, He M, Zhang Z, Dohner K, Neilly MB, Price C, Lussier YA, Zhang Y, Larson RA, Le Beau MM, Caligiuri MA, Bullinger L, Valk PJ, Delwel R, Lowenberg B, Liu PP, Marcucci G, Bloomfield CD, Rowley JD, Chen J.

Blood. 2012 Mar 8;119(10):2314-24. doi: 10.1182/blood-2011-10-386235. Epub 2012 Jan 17.

13.

Chronic myeloid leukemia: current perspectives.

Zhang Y, Rowley JD.

Clin Lab Med. 2011 Dec;31(4):687-98, x. doi: 10.1016/j.cll.2011.08.012. Epub 2011 Oct 14. Review.

PMID:
22118744
14.

Targeting mutations predictably.

Schreiber H, Rowley JD, Rowley DA.

Blood. 2011 Jul 28;118(4):830-1. doi: 10.1182/blood-2011-06-357541. No abstract available.

PMID:
21799095
15.

Philadelphia Chromosome Symposium: commemoration of the 50th anniversary of the discovery of the Ph chromosome.

Chandra HS, Heisterkamp NC, Hungerford A, Morrissette JJ, Nowell PC, Rowley JD, Testa JR.

Cancer Genet. 2011 Apr;204(4):171-9. doi: 10.1016/j.cancergen.2011.03.002.

16.

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia.

Mi S, Li Z, Chen P, He C, Cao D, Elkahloun A, Lu J, Pelloso LA, Wunderlich M, Huang H, Luo RT, Sun M, He M, Neilly MB, Zeleznik-Le NJ, Thirman MJ, Mulloy JC, Liu PP, Rowley JD, Chen J.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3710-5. doi: 10.1073/pnas.0914900107. Epub 2010 Feb 2.

17.

Leukaemogenesis: more than mutant genes.

Chen J, Odenike O, Rowley JD.

Nat Rev Cancer. 2010 Jan;10(1):23-36. doi: 10.1038/nrc2765. Review.

18.

Chromosomes in leukemia and beyond: from irrelevant to central players.

Rowley JD.

Annu Rev Genomics Hum Genet. 2009;10:1-18. doi: 10.1146/annurev-genom-082908-150144.

PMID:
19715438
19.

The transcriptome of human CD34+ hematopoietic stem-progenitor cells.

Kim YC, Wu Q, Chen J, Xuan Z, Jung YC, Zhang MQ, Rowley JD, Wang SM.

Proc Natl Acad Sci U S A. 2009 May 19;106(20):8278-83. doi: 10.1073/pnas.0903390106. Epub 2009 Apr 30.

20.

Regulation of mir-196b by MLL and its overexpression by MLL fusions contributes to immortalization.

Popovic R, Riesbeck LE, Velu CS, Chaubey A, Zhang J, Achille NJ, Erfurth FE, Eaton K, Lu J, Grimes HL, Chen J, Rowley JD, Zeleznik-Le NJ.

Blood. 2009 Apr 2;113(14):3314-22. doi: 10.1182/blood-2008-04-154310. Epub 2009 Feb 2.

21.

Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.

Li Z, Luo RT, Mi S, Sun M, Chen P, Bao J, Neilly MB, Jayathilaka N, Johnson DS, Wang L, Lavau C, Zhang Y, Tseng C, Zhang X, Wang J, Yu J, Yang H, Wang SM, Rowley JD, Chen J, Thirman MJ.

Cancer Res. 2009 Feb 1;69(3):1109-16. doi: 10.1158/0008-5472.CAN-08-3381. Epub 2009 Jan 20.

22.

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.

Li Z, Lu J, Sun M, Mi S, Zhang H, Luo RT, Chen P, Wang Y, Yan M, Qian Z, Neilly MB, Jin J, Zhang Y, Bohlander SK, Zhang DE, Larson RA, Le Beau MM, Thirman MJ, Golub TR, Rowley JD, Chen J.

Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15535-40. doi: 10.1073/pnas.0808266105. Epub 2008 Oct 1.

23.

Chromosomal translocations: revisited yet again.

Rowley JD.

Blood. 2008 Sep 15;112(6):2183-9. doi: 10.1182/blood-2008-04-097931. Review. No abstract available.

PMID:
18779403
24.

Medicine. The cart before the horse.

Rowley JD, Blumenthal T.

Science. 2008 Sep 5;321(5894):1302-4. doi: 10.1126/science.1163791. No abstract available.

PMID:
18772424
25.

Comparative gene mapping in cattle, Indian muntjac, and Chinese muntjac by fluorescence in situ hybridization.

Murmann AE, Mincheva A, Scheuermann MO, Gautier M, Yang F, Buitkamp J, Strissel PL, Strick R, Rowley JD, Lichter P.

Genetica. 2008 Nov;134(3):345-51. doi: 10.1007/s10709-008-9242-1. Epub 2008 Feb 19.

PMID:
18283540
26.

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.

Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, Wang Y, Qian Z, Jin J, Zhang Y, Bohlander SK, Le Beau MM, Larson RA, Golub TR, Rowley JD, Chen J.

Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19971-6. Epub 2007 Dec 4.

27.

Cytogenetic and molecular study of the PRDX4 gene in a t(X;18)(p22;q23): a cautionary tale.

Gerr HD, Nassin ML, Davis EM, Jayathilaka N, Neilly ME, Schlegelberger B, Zhang Y, Rowley JD.

Cancer Genet Cytogenet. 2007 Jul 15;176(2):131-6.

28.

Methylation-independent silencing of the tumor suppressor INK4b (p15) by CBFbeta-SMMHC in acute myelogenous leukemia with inv(16).

Markus J, Garin MT, Bies J, Galili N, Raza A, Thirman MJ, Le Beau MM, Rowley JD, Liu PP, Wolff L.

Cancer Res. 2007 Feb 1;67(3):992-1000.

29.

ISCN (2005) is not acceptable for describing clonal evolution in cancer.

Mitelman F, Rowley JD.

Genes Chromosomes Cancer. 2007 Mar;46(3):213-4. No abstract available.

PMID:
17171683
30.

Chromatin structural elements and chromosomal translocations in leukemia.

Zhang Y, Rowley JD.

DNA Repair (Amst). 2006 Sep 8;5(9-10):1282-97. Epub 2006 Aug 7. Review.

PMID:
16893685
31.

A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis.

Yan M, Kanbe E, Peterson LF, Boyapati A, Miao Y, Wang Y, Chen IM, Chen Z, Rowley JD, Willman CL, Zhang DE.

Nat Med. 2006 Aug;12(8):945-9. Epub 2006 Jul 30.

PMID:
16892037
32.

Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.

Lee S, Chen J, Zhou G, Shi RZ, Bouffard GG, Kocherginsky M, Ge X, Sun M, Jayathilaka N, Kim YC, Emmanuel N, Bohlander SK, Minden M, Kline J, Ozer O, Larson RA, LeBeau MM, Green ED, Trent J, Karrison T, Liu PP, Wang SM, Rowley JD.

Proc Natl Acad Sci U S A. 2006 Jan 24;103(4):1030-5. Epub 2006 Jan 17.

33.

Local gene density predicts the spatial position of genetic loci in the interphase nucleus.

Murmann AE, Gao J, Encinosa M, Gautier M, Peter ME, Eils R, Lichter P, Rowley JD.

Exp Cell Res. 2005 Nov 15;311(1):14-26. Epub 2005 Oct 3.

PMID:
16202404
34.
35.

Knockdown of Pu.1 by small interfering RNA in CD34+ embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells.

Zou GM, Chen JJ, Yoder MC, Wu W, Rowley JD.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13236-41. Epub 2005 Sep 1.

36.

Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells.

Feldhahn N, Río P, Soh BN, Liedtke S, Sprangers M, Klein F, Wernet P, Jumaa H, Hofmann WK, Hanenberg H, Rowley JD, Müschen M.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13266-71. Epub 2005 Sep 2.

37.

Mimicry of a constitutively active pre-B cell receptor in acute lymphoblastic leukemia cells.

Feldhahn N, Klein F, Mooster JL, Hadweh P, Sprangers M, Wartenberg M, Bekhite MM, Hofmann WK, Herzog S, Jumaa H, Rowley JD, Müschen M.

J Exp Med. 2005 Jun 6;201(11):1837-52.

38.

Genome-wide analysis of coordinate expression and evolution of human cis-encoded sense-antisense transcripts.

Chen J, Sun M, Hurst LD, Carmichael GG, Rowley JD.

Trends Genet. 2005 Jun;21(6):326-9.

PMID:
15922830
39.

Human antisense genes have unusually short introns: evidence for selection for rapid transcription.

Chen J, Sun M, Hurst LD, Carmichael GG, Rowley JD.

Trends Genet. 2005 Apr;21(4):203-7.

PMID:
15797613
40.

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements.

Kobzev YN, Martinez-Climent J, Lee S, Chen J, Rowley JD.

Genes Chromosomes Cancer. 2004 Dec;41(4):339-52.

PMID:
15390187
41.

Over 20% of human transcripts might form sense-antisense pairs.

Chen J, Sun M, Kent WJ, Huang X, Xie H, Wang W, Zhou G, Shi RZ, Rowley JD.

Nucleic Acids Res. 2004 Sep 8;32(16):4812-20. Print 2004.

42.

Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16).

Zhang Y, Zeleznik-Le N, Emmanuel N, Jayathilaka N, Chen J, Strissel P, Strick R, Li L, Neilly MB, Taki T, Hayashi Y, Kaneko Y, Schlegelberger B, Rowley JD.

Genes Chromosomes Cancer. 2004 Nov;41(3):257-65.

PMID:
15334549
43.

The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin.

Helbling D, Mueller BU, Timchenko NA, Hagemeijer A, Jotterand M, Meyer-Monard S, Lister A, Rowley JD, Huegli B, Fey MF, Pabst T.

Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13312-7. Epub 2004 Aug 23.

44.

PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22).

Zhang Y, Emmanuel N, Kamboj G, Chen J, Shurafa M, Van Dyke DL, Wiktor A, Rowley JD.

Genes Chromosomes Cancer. 2004 Aug;40(4):365-70.

PMID:
15188461
45.

Duplexes of 21-nucleotide RNAs mediate RNA interference in differentiated mouse ES cells.

Zou GM, Wu W, Chen J, Rowley JD.

Biol Cell. 2003 Sep;95(6):365-71.

PMID:
14519553
46.

Prognostic significance of the AML1-ETO fusion transcript expression in children and young adults with t(8;21) acute myeloid leukemia.

Fleischman EW, Baturina JA, Sokova OI, Popa AV, Kosorukova IS, Rowley JD.

Haematologica. 2003 Sep;88(9):1078-9. No abstract available.

47.

Screening and quantification of multiple chromosome translocations in human leukemia.

Shi RZ, Morrissey JM, Rowley JD.

Clin Chem. 2003 Jul;49(7):1066-73.

48.

T lymphoid differentiation in human bone marrow.

Klein F, Feldhahn N, Lee S, Wang H, Ciuffi F, von Elstermann M, Toribio ML, Sauer H, Wartenberg M, Barath VS, Krönke M, Wernet P, Rowley JD, Müschen M.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6747-52. Epub 2003 May 8.

49.

Generation of longer cDNA fragments from SAGE tags for gene identification.

Chen JJ, Lee S, Zhou G, Rowley JD, Wang SM.

Methods Mol Biol. 2003;221:207-22. No abstract available.

PMID:
12703746
50.

Screening poly [dA/dT(-)] cDNA for gene identification.

Wang SM, Fears SC, Zhang L, Chen JJ, Rowley JD.

Methods Mol Biol. 2003;221:197-205. No abstract available.

PMID:
12703745

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