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Items: 49


Genetic Deletion of Syndecan-4 Alters Body Composition, Metabolic Phenotypes, and the Function of Metabolic Tissues in Female Mice Fed A High-Fat Diet.

De Luca M, Vecchie' D, Athmanathan B, Gopalkrishna S, Valcin JA, Swain TM, Sertie R, Wekesa K, Rowe GC, Bailey SM, Nagareddy PR.

Nutrients. 2019 Nov 18;11(11). pii: E2810. doi: 10.3390/nu11112810.


The Role of Lipopolysaccharide-Induced Extracellular Vesicles in Cardiac Cell Death.

Bell CR, Jones LB, Crenshaw BJ, Kumar S, Rowe GC, Sims B, Javan GT, Matthews QL.

Biology (Basel). 2019 Sep 23;8(4). pii: E69. doi: 10.3390/biology8040069.


Geographic Variance in Maryland's Potentially Preventable Emergency Visits: Comparison of Explanatory Models.

Rowe GC.

West J Nurs Res. 2019 Aug 2:193945919867938. doi: 10.1177/0193945919867938. [Epub ahead of print]


HDAC inhibition induces autophagy and mitochondrial biogenesis to maintain mitochondrial homeostasis during cardiac ischemia/reperfusion injury.

Yang J, He J, Ismail M, Tweeten S, Zeng F, Gao L, Ballinger S, Young M, Prabhu SD, Rowe GC, Zhang J, Zhou L, Xie M.

J Mol Cell Cardiol. 2019 May;130:36-48. doi: 10.1016/j.yjmcc.2019.03.008. Epub 2019 Mar 14.


Age- and Genotype-Specific Effects of the Angiotensin-Converting Enzyme Inhibitor Lisinopril on Mitochondrial and Metabolic Parameters in Drosophila melanogaster.

Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M.

Int J Mol Sci. 2018 Oct 26;19(11). pii: E3351. doi: 10.3390/ijms19113351.


Adult skeletal muscle deletion of Mitofusin 1 and 2 impedes exercise performance and training capacity.

Bell MB, Bush Z, McGinnis GR, Rowe GC.

J Appl Physiol (1985). 2019 Feb 1;126(2):341-353. doi: 10.1152/japplphysiol.00719.2018. Epub 2018 Sep 27.


Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment.

McMeekin LJ, Li Y, Fox SN, Rowe GC, Crossman DK, Day JJ, Li Y, Detloff PJ, Cowell RM.

J Neurosci. 2018 Mar 28;38(13):3273-3286. doi: 10.1523/JNEUROSCI.0848-17.2018. Epub 2018 Feb 28.


PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy.

Liu LX, Rowe GC, Yang S, Li J, Damilano F, Chan MC, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann BK, Rabinowitz JD, Das S, Rosenzweig A, Arany Z.

Circ Res. 2017 Dec 8;121(12):1370-1378. doi: 10.1161/CIRCRESAHA.117.311456. Epub 2017 Sep 19.


Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart.

McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Abel ED, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, Chatham JC, Young ME.

J Mol Cell Cardiol. 2017 Sep;110:80-95. doi: 10.1016/j.yjmcc.2017.07.005. Epub 2017 Jul 20.


miR-29b contributes to multiple types of muscle atrophy.

Li J, Chan MC, Yu Y, Bei Y, Chen P, Zhou Q, Cheng L, Chen L, Ziegler O, Rowe GC, Das S, Xiao J.

Nat Commun. 2017 May 25;8:15201. doi: 10.1038/ncomms15201.


VEGF-B: friend or foe to the heart in times of nutrient excess?

Rowe GC, Young ME.

Am J Physiol Heart Circ Physiol. 2017 Aug 1;313(2):H244-H247. doi: 10.1152/ajpheart.00158.2017. Epub 2017 May 19. No abstract available.


Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function.

McDermott-Roe C, Leleu M, Rowe GC, Palygin O, Bukowy JD, Kuo J, Rech M, Hermans-Beijnsberger S, Schaefer S, Adami E, Creemers EE, Heinig M, Schroen B, Arany Z, Petretto E, Geurts AM.

PLoS One. 2017 Feb 3;12(2):e0170458. doi: 10.1371/journal.pone.0170458. eCollection 2017.


Development of dilated cardiomyopathy and impaired calcium homeostasis with cardiac-specific deletion of ESRRβ.

Rowe GC, Asimaki A, Graham EL, Martin KD, Margulies KB, Das S, Saffitz J, Arany Z.

Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H662-H671. doi: 10.1152/ajpheart.00446.2016. Epub 2017 Jan 27.


Hypothalamic ΔFosB prevents age-related metabolic decline and functions via SNS.

Sato K, Idelevich A, Nagano K, Rowe GC, Gori F, Baron R.

Aging (Albany NY). 2017 Jan 20;9(2):353-369. doi: 10.18632/aging.101157.


LDB1 Regulates Energy Homeostasis During Diet-Induced Obesity.

Loyd C, Liu Y, Kim T, Holleman C, Galloway J, Bethea M, Ediger BN, Swain TA, Tang Y, Stoffers DA, Rowe GC, Young M, Steele C, Habegger KM, Hunter CS.

Endocrinology. 2017 May 1;158(5):1289-1297. doi: 10.1210/en.2016-1791.


The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.

Wada S, Neinast M, Jang C, Ibrahim YH, Lee G, Babu A, Li J, Hoshino A, Rowe GC, Rhee J, Martina JA, Puertollano R, Blenis J, Morley M, Baur JA, Seale P, Arany Z.

Genes Dev. 2016 Nov 15;30(22):2551-2564. Epub 2016 Dec 2.


Heme oxygenase and carbon monoxide protect from muscle dystrophy.

Chan MC, Ziegler O, Liu L, Rowe GC, Das S, Otterbein LE, Arany Z.

Skelet Muscle. 2016 Nov 28;6(1):41.


Adult expression of PGC-1α and -1β in skeletal muscle is not required for endurance exercise-induced enhancement of exercise capacity.

Ballmann C, Tang Y, Bush Z, Rowe GC.

Am J Physiol Endocrinol Metab. 2016 Dec 1;311(6):E928-E938. doi: 10.1152/ajpendo.00209.2016. Epub 2016 Oct 25.


The TreadWheel: A Novel Apparatus to Measure Genetic Variation in Response to Gently Induced Exercise for Drosophila.

Mendez S, Watanabe L, Hill R, Owens M, Moraczewski J, Rowe GC, Riddle NC, Reed LK.

PLoS One. 2016 Oct 13;11(10):e0164706. doi: 10.1371/journal.pone.0164706. eCollection 2016.


Biotinylation: a novel posttranslational modification linking cell autonomous circadian clocks with metabolism.

He L, Hamm JA, Reddy A, Sams D, Peliciari-Garcia RA, McGinnis GR, Bailey SM, Chow CW, Rowe GC, Chatham JC, Young ME.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1520-32. doi: 10.1152/ajpheart.00959.2015. Epub 2016 Apr 15.


PGC-1α Induces Human RPE Oxidative Metabolism and Antioxidant Capacity.

Iacovelli J, Rowe GC, Khadka A, Diaz-Aguilar D, Spencer C, Arany Z, Saint-Geniez M.

Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1038-51. doi: 10.1167/iovs.15-17758.


A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.

Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z.

Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7.


Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice.

Safdar A, Khrapko K, Flynn JM, Saleem A, De Lisio M, Johnston AP, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, Rowe GC, Arany Z, Prolla TA, Tarnopolsky MA.

Skelet Muscle. 2016 Jan 31;6:7. doi: 10.1186/s13395-016-0075-9. eCollection 2016.


A statewide assessment of smoke-free policy in multiunit housing settings.

Burdette LK, Rowe GC, Johansen L, Kerkvliet JL, Nagelhout E, Lewis K, Fahrenwald NL.

Nicotine Tob Res. 2014 Dec;16(12):1593-8. doi: 10.1093/ntr/ntu114. Epub 2014 Jul 23.


PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle.

Rowe GC, Raghuram S, Jang C, Nagy JA, Patten IS, Goyal A, Chan MC, Liu LX, Jiang A, Spokes KC, Beeler D, Dvorak H, Aird WC, Arany Z.

Circ Res. 2014 Aug 15;115(5):504-17. doi: 10.1161/CIRCRESAHA.115.303829. Epub 2014 Jul 9.


Running forward: new frontiers in endurance exercise biology.

Rowe GC, Safdar A, Arany Z.

Circulation. 2014 Feb 18;129(7):798-810. doi: 10.1161/CIRCULATIONAHA.113.001590. Review. No abstract available.


Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor γ coactivator (PGC)-1α.

Thom R, Rowe GC, Jang C, Safdar A, Arany Z.

J Biol Chem. 2014 Mar 28;289(13):8810-7. doi: 10.1074/jbc.M114.554394. Epub 2014 Feb 6.


Post-natal induction of PGC-1α protects against severe muscle dystrophy independently of utrophin.

Chan MC, Rowe GC, Raghuram S, Patten IS, Farrell C, Arany Z.

Skelet Muscle. 2014 Jan 22;4(1):2. doi: 10.1186/2044-5040-4-2.


WITHDRAWN: Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by N-Terminus Peroxisome Proliferator-Activated Receptor Gamma Coactivator (NT-PGC)-1alpha.

Thom R, Rowe GC, Jang C, Safdar A, White JP, Arany Z.

J Biol Chem. 2014 Jan 15. doi: 10.1074/jbc.M113.512061. Epub 2014 Jan 15. No abstract available. Retraction in: J Biol Chem. 2015 Aug 7;290(32):19543.


Genetic models of PGC-1 and glucose metabolism and homeostasis.

Rowe GC, Arany Z.

Rev Endocr Metab Disord. 2014 Mar;15(1):21-9. doi: 10.1007/s11154-013-9273-5. Review.


Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle.

Rowe GC, Patten IS, Zsengeller ZK, El-Khoury R, Okutsu M, Bampoh S, Koulisis N, Farrell C, Hirshman MF, Yan Z, Goodyear LJ, Rustin P, Arany Z.

Cell Rep. 2013 May 30;3(5):1449-56. doi: 10.1016/j.celrep.2013.04.023. Epub 2013 May 23.


Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

Haq R, Shoag J, Andreu-Perez P, Yokoyama S, Edelman H, Rowe GC, Frederick DT, Hurley AD, Nellore A, Kung AL, Wargo JA, Song JS, Fisher DE, Arany Z, Widlund HR.

Cancer Cell. 2013 Mar 18;23(3):302-15. doi: 10.1016/j.ccr.2013.02.003. Epub 2013 Mar 7.


PGC-1 coactivators regulate MITF and the tanning response.

Shoag J, Haq R, Zhang M, Liu L, Rowe GC, Jiang A, Koulisis N, Farrel C, Amos CI, Wei Q, Lee JE, Zhang J, Kupper TS, Qureshi AA, Cui R, Han J, Fisher DE, Arany Z.

Mol Cell. 2013 Jan 10;49(1):145-57. doi: 10.1016/j.molcel.2012.10.027. Epub 2012 Nov 29.


PGC-1α is dispensable for exercise-induced mitochondrial biogenesis in skeletal muscle.

Rowe GC, El-Khoury R, Patten IS, Rustin P, Arany Z.

PLoS One. 2012;7(7):e41817. doi: 10.1371/journal.pone.0041817. Epub 2012 Jul 24.


Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.

Patten IS, Rana S, Shahul S, Rowe GC, Jang C, Liu L, Hacker MR, Rhee JS, Mitchell J, Mahmood F, Hess P, Farrell C, Koulisis N, Khankin EV, Burke SD, Tudorache I, Bauersachs J, del Monte F, Hilfiker-Kleiner D, Karumanchi SA, Arany Z.

Nature. 2012 May 9;485(7398):333-8. doi: 10.1038/nature11040.


Energy expenditure and bone formation share a common sensitivity to AP-1 transcription in the hypothalamus.

Rowe GC, Vialou V, Sato K, Saito H, Yin M, Green TA, Lotinun S, Kveiborg M, Horne WC, Nestler EJ, Baron R.

J Bone Miner Res. 2012 Aug;27(8):1649-58. doi: 10.1002/jbmr.1618.


Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.

Finley LW, Lee J, Souza A, Desquiret-Dumas V, Bullock K, Rowe GC, Procaccio V, Clish CB, Arany Z, Haigis MC.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2931-6. doi: 10.1073/pnas.1115813109. Epub 2012 Feb 3.


Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

McDermott-Roe C, Ye J, Ahmed R, Sun XM, Serafín A, Ware J, Bottolo L, Muckett P, Cañas X, Zhang J, Rowe GC, Buchan R, Lu H, Braithwaite A, Mancini M, Hauton D, Martí R, García-Arumí E, Hubner N, Jacob H, Serikawa T, Zidek V, Papousek F, Kolar F, Cardona M, Ruiz-Meana M, García-Dorado D, Comella JX, Felkin LE, Barton PJ, Arany Z, Pravenec M, Petretto E, Sanchis D, Cook SA.

Nature. 2011 Oct 5;478(7367):114-8. doi: 10.1038/nature10490.


PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice.

Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A, Zsengeller ZK, Akhavan-Sharif MR, Khankin EV, Saintgeniez M, David S, Burstein D, Karumanchi SA, Stillman IE, Arany Z, Parikh SM.

J Clin Invest. 2011 Oct;121(10):4003-14. doi: 10.1172/JCI58662. Epub 2011 Sep 1.


PGC-1β regulates angiogenesis in skeletal muscle.

Rowe GC, Jang C, Patten IS, Arany Z.

Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E155-63. doi: 10.1152/ajpendo.00681.2010. Epub 2011 Mar 1.


PGC-1 coactivators in cardiac development and disease.

Rowe GC, Jiang A, Arany Z.

Circ Res. 2010 Oct 1;107(7):825-38. doi: 10.1161/CIRCRESAHA.110.223818. Review.


Metabolic signatures of exercise in human plasma.

Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE.

Sci Transl Med. 2010 May 26;2(33):33ra37. doi: 10.1126/scitranslmed.3001006.


The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle.

Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, Rowe GC, Sawada N, Raghuram S, Arany Z.

Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21401-6. doi: 10.1073/pnas.0909131106. Epub 2009 Dec 4.


Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo.

Wu M, Hesse E, Morvan F, Zhang JP, Correa D, Rowe GC, Kiviranta R, Neff L, Philbrick WM, Horne WC, Baron R.

Bone. 2009 Apr;44(4):528-36. doi: 10.1016/j.bone.2008.11.011. Epub 2008 Nov 27.


Increased energy expenditure and insulin sensitivity in the high bone mass DeltaFosB transgenic mice.

Rowe GC, Choi CS, Neff L, Horne WC, Shulman GI, Baron R.

Endocrinology. 2009 Jan;150(1):135-43. doi: 10.1210/en.2008-0678. Epub 2008 Sep 4.


Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity.

Sabatakos G, Rowe GC, Kveiborg M, Wu M, Neff L, Chiusaroli R, Philbrick WM, Baron R.

J Bone Miner Res. 2008 May;23(5):584-95. doi: 10.1359/jbmr.080110.


Novel antineoplastic isochalcones inhibit the expression of cyclooxygenase 1,2 and EGF in human prostate cancer cell line LNCaP.

Johnson KP, Rowe GC, Jackson BA, D'Agustino JL, Campbell PE, Guillory BO, Williams MV, Matthews QL, McKay J, Charles GM, Verret CR, Deleon M, Johnson DE, Cooke DB.

Cell Mol Biol (Noisy-le-grand). 2001 Sep;47(6):1039-45.




Am Heart J. 1964 Mar;67:334-7. No abstract available.


Drug therapy during cardiac arrest.


Wis Med J. 1959 Nov;58:663-5. No abstract available.


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