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Natural history of pain associated with melanoma surgery.

Slagelse C, Munch T, Glazer C, Greene K, Finnerup NB, Kashani-Sabet M, Leong SP, Petersen KL, Rowbotham MC.

Pain Rep. 2018 Oct 19;3(6):e689. doi: 10.1097/PR9.0000000000000689. eCollection 2018 Nov.


The IASP classification of chronic pain for ICD-11: chronic neuropathic pain.

Scholz J, Finnerup NB, Attal N, Aziz Q, Baron R, Bennett MI, Benoliel R, Cohen M, Cruccu G, Davis KD, Evers S, First M, Giamberardino MA, Hansson P, Kaasa S, Korwisi B, Kosek E, Lavandʼhomme P, Nicholas M, Nurmikko T, Perrot S, Raja SN, Rice ASC, Rowbotham MC, Schug S, Simpson DM, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ, Barke A, Rief W, Treede RD; Classification Committee of the Neuropathic Pain Special Interest Group (NeuPSIG).

Pain. 2019 Jan;160(1):53-59. doi: 10.1097/j.pain.0000000000001365. Review.


Evaluation of composite responder outcomes of pain intensity and physical function in neuropathic pain clinical trials: an ACTTION individual patient data analysis.

Patel KV, Allen R, Burke L, Farrar JT, Gewandter JS, Gilron I, Katz NP, Markman JD, Marshall SF, Resnick M, Rice ASC, Rowbotham MC, Smith SM, Vanhove GF, Wasan AD, Zhang S, Dworkin RH, Turk DC.

Pain. 2018 Nov;159(11):2245-2254. doi: 10.1097/j.pain.0000000000001324.


The Potential Role of Sensory Testing, Skin Biopsy, and Functional Brain Imaging as Biomarkers in Chronic Pain Clinical Trials: IMMPACT Considerations.

Smith SM, Dworkin RH, Turk DC, Baron R, Polydefkis M, Tracey I, Borsook D, Edwards RR, Harris RE, Wager TD, Arendt-Nielsen L, Burke LB, Carr DB, Chappell A, Farrar JT, Freeman R, Gilron I, Goli V, Haeussler J, Jensen T, Katz NP, Kent J, Kopecky EA, Lee DA, Maixner W, Markman JD, McArthur JC, McDermott MP, Parvathenani L, Raja SN, Rappaport BA, Rice ASC, Rowbotham MC, Tobias JK, Wasan AD, Witter J.

J Pain. 2017 Jul;18(7):757-777. doi: 10.1016/j.jpain.2017.02.429. Epub 2017 Feb 27. Review.


Informed Consent.

Grady C, Cummings SR, Rowbotham MC, McConnell MV, Ashley EA, Kang G.

N Engl J Med. 2017 Mar 2;376(9):856-867. doi: 10.1056/NEJMra1603773. Review. No abstract available.


Reporting of data monitoring boards in publications of randomized clinical trials is often deficient: ACTTION systematic review.

Gewandter JS, Kitt RA, Hunsinger MR, Poku J, Lozano J, Chaudari J, Evans S, Gross RA, McDermott MP, Rowbotham MC, Turk DC, Dworkin RH.

J Clin Epidemiol. 2017 Mar;83:101-107. doi: 10.1016/j.jclinepi.2016.12.018. Epub 2017 Jan 23. Review.


Adverse Event Reporting in Clinical Trials of Intravenous and Invasive Pain Treatments: An ACTTION Systematic Review.

Williams MR, McKeown A, Pressman Z, Hunsinger M, Lee K, Coplan P, Gilron I, Katz NP, McDermott MP, Raja SN, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM.

J Pain. 2016 Nov;17(11):1137-1149. doi: 10.1016/j.jpain.2016.07.006. Epub 2016 Aug 12. Review.


Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults.

Tranah GJ, Yaffe K, Katzman SM, Lam ET, Pawlikowska L, Kwok PY, Schork NJ, Manini TM, Kritchevsky S, Thomas F, Newman AB, Harris TB, Coleman AL, Gorin MB, Helzner EP, Rowbotham MC, Browner WS, Cummings SR; Health, Aging and Body Composition Study.

J Gerontol A Biol Sci Med Sci. 2015 Nov;70(11):1418-24. doi: 10.1093/gerona/glv097. Epub 2015 Aug 31.


Tricyclic antidepressants and opioids-better together?

Rowbotham MC.

Pain. 2015 Aug;156(8):1373-4. doi: 10.1097/j.pain.0000000000000189. No abstract available.


Results availability for analgesic device, complex regional pain syndrome, and post-stroke pain trials: comparing the RReADS, RReACT, and RReMiT databases.

Dufka FL, Munch T, Dworkin RH, Rowbotham MC.

Pain. 2015 Jan;156(1):72-80. doi: 10.1016/j.pain.0000000000000009.


Reporting of sample size calculations in analgesic clinical trials: ACTTION systematic review.

McKeown A, Gewandter JS, McDermott MP, Pawlowski JR, Poli JJ, Rothstein D, Farrar JT, Gilron I, Katz NP, Lin AH, Rappaport BA, Rowbotham MC, Turk DC, Dworkin RH, Smith SM.

J Pain. 2015 Mar;16(3):199-206.e1-7. doi: 10.1016/j.jpain.2014.11.010. Epub 2014 Dec 4. Review.


Data interpretation in analgesic clinical trials with statistically nonsignificant primary analyses: an ACTTION systematic review.

Gewandter JS, McKeown A, McDermott MP, Dworkin JD, Smith SM, Gross RA, Hunsinger M, Lin AH, Rappaport BA, Rice AS, Rowbotham MC, Williams MR, Turk DC, Dworkin RH.

J Pain. 2015 Jan;16(1):3-10. doi: 10.1016/j.jpain.2014.10.003. Epub 2014 Oct 23. Review.


Reporting of intention-to-treat analyses in recent analgesic clinical trials: ACTTION systematic review and recommendations.

Gewandter JS, McDermott MP, McKeown A, Smith SM, Pawlowski JR, Poli JJ, Rothstein D, Williams MR, Bujanover S, Farrar JT, Gilron I, Katz NP, Rowbotham MC, Turk DC, Dworkin RH.

Pain. 2014 Dec;155(12):2714-9. doi: 10.1016/j.pain.2014.09.039. Epub 2014 Oct 2. Review.


How transparent are migraine clinical trials? Repository of Registered Migraine Trials (RReMiT).

Dufka FL, Dworkin RH, Rowbotham MC.

Neurology. 2014 Oct 7;83(15):1372-81. doi: 10.1212/WNL.0000000000000866. Epub 2014 Sep 5.


Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations.

Gewandter JS, Dworkin RH, Turk DC, McDermott MP, Baron R, Gastonguay MR, Gilron I, Katz NP, Mehta C, Raja SN, Senn S, Taylor C, Cowan P, Desjardins P, Dimitrova R, Dionne R, Farrar JT, Hewitt DJ, Iyengar S, Jay GW, Kalso E, Kerns RD, Leff R, Leong M, Petersen KL, Ravina BM, Rauschkolb C, Rice AS, Rowbotham MC, Sampaio C, Sindrup SH, Stauffer JW, Steigerwald I, Stewart J, Tobias J, Treede RD, Wallace M, White RE.

Pain. 2014 Sep;155(9):1683-95. doi: 10.1016/j.pain.2014.05.025. Epub 2014 May 24. Review.


Effect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: an ACTTION study.

Farrar JT, Troxel AB, Haynes K, Gilron I, Kerns RD, Katz NP, Rappaport BA, Rowbotham MC, Tierney AM, Turk DC, Dworkin RH.

Pain. 2014 Aug;155(8):1622-31. doi: 10.1016/j.pain.2014.05.009. Epub 2014 May 14.


RReACT goes global: perils and pitfalls of constructing a global open-access database of registered analgesic clinical trials and trial results.

Munch T, Dufka FL, Greene K, Smith SM, Dworkin RH, Rowbotham MC.

Pain. 2014 Jul;155(7):1313-7. doi: 10.1016/j.pain.2014.04.007. Epub 2014 Apr 13.


Correction: Shaped Magnetic Field Pulses by Multi-Coil Repetitive Transcranial Magnetic Stimulation (rTMS) Differentially Modulate Anterior Cingulate Cortex Responses and Pain in Volunteers and Fibromyalgia Patients.

Tzabazis A, Aparici CM, Rowbotham MC, Schneider MB, Etkin A, Yeomans DC.

Mol Pain. 2014 Jan-Dec;10:174480691016. doi: 10.1186/1744-8069-10-16. No abstract available.


Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations.

O'Connor AB, Turk DC, Dworkin RH, Katz NP, Colucci R, Haythornthwaite JA, Klein M, O'Brien C, Posner K, Rappaport BA, Reisfield G, Adams EH, Balster RL, Bigelow GE, Burke LB, Comer SD, Cone E, Cowan P, Denisco RA, Farrar JT, Foltin RW, Haddox JD, Hertz S, Jay GW, Junor R, Kopecky EA, Leiderman DB, McDermott MP, Palmer PP, Raja SN, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Smith SM, Sokolowska M, Stauffer JW, Walsh SL, Zacny JP.

Pain. 2013 Nov;154(11):2324-34. doi: 10.1016/j.pain.2013.06.035. Review.


Discrepancies between registered and published primary outcome specifications in analgesic trials: ACTTION systematic review and recommendations.

Smith SM, Wang AT, Pereira A, Chang RD, McKeown A, Greene K, Rowbotham MC, Burke LB, Coplan P, Gilron I, Hertz SH, Katz NP, Lin AH, McDermott MP, Papadopoulos EJ, Rappaport BA, Sweeney M, Turk DC, Dworkin RH.

Pain. 2013 Dec;154(12):2769-74. doi: 10.1016/j.pain.2013.08.011. Epub 2013 Aug 17. Review.


Does naloxone reinstate secondary hyperalgesia in humans after resolution of a burn injury? A placebo-controlled, double-blind, randomized, cross-over study.

Pereira MP, Werner MU, Ringsted TK, Rowbotham MC, Taylor BK, Dahl JB.

PLoS One. 2013 May 31;8(5):e64608. doi: 10.1371/journal.pone.0064608. Print 2013.


Natural history of herpes zoster: late follow-up of 3.9 years (n=43) and 7.7 years (n=10).

Reda H, Greene K, Rice FL, Rowbotham MC, Petersen KL.

Pain. 2013 Oct;154(10):2227-33. doi: 10.1016/j.pain.2013.04.015. Epub 2013 Apr 11.


Assay sensitivity and study features in neuropathic pain trials: an ACTTION meta-analysis.

Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Farrar JT, Katz NP, Lin AH, Rappaport BA, Rowbotham MC.

Neurology. 2013 Jul 2;81(1):67-75. doi: 10.1212/WNL.0b013e318297ee69. Epub 2013 May 22.


Healthy volunteers can be phenotyped using cutaneous sensitization pain models.

Werner MU, Petersen KL, Rowbotham MC, Dahl JB.

PLoS One. 2013 May 9;8(5):e62733. doi: 10.1371/journal.pone.0062733. Print 2013.


Adverse event assessment, analysis, and reporting in recent published analgesic clinical trials: ACTTION systematic review and recommendations.

Smith SM, Wang AT, Katz NP, McDermott MP, Burke LB, Coplan P, Gilron I, Hertz SH, Lin AH, Rappaport BA, Rowbotham MC, Sampaio C, Sweeney M, Turk DC, Dworkin RH.

Pain. 2013 Jul;154(7):997-1008. doi: 10.1016/j.pain.2013.03.003. Epub 2013 Mar 14.


Can pragmatic trials help us better understand chronic pain and improve treatment?

Rowbotham MC, Gilron I, Glazer C, Rice AS, Smith BH, Stewart WF, Wasan AD.

Pain. 2013 May;154(5):643-6. doi: 10.1016/j.pain.2013.02.034. Epub 2013 Mar 7. Review. No abstract available.


Interactive informed consent: randomized comparison with paper consents.

Rowbotham MC, Astin J, Greene K, Cummings SR.

PLoS One. 2013;8(3):e58603. doi: 10.1371/journal.pone.0058603. Epub 2013 Mar 6.


Neuropathic pain needs systematic classification.

Finnerup NB, Scholz J, Attal N, Baron R, Haanpää M, Hansson P, Raja SN, Rice AS, Rief W, Rowbotham MC, Simpson DM, Treede RD.

Eur J Pain. 2013 Aug;17(7):953-6. doi: 10.1002/j.1532-2149.2012.00282.x. Epub 2013 Jan 21. Review. No abstract available.


Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations.

Comer SD, Zacny JP, Dworkin RH, Turk DC, Bigelow GE, Foltin RW, Jasinski DR, Sellers EM, Adams EH, Balster R, Burke LB, Cerny I, Colucci RD, Cone E, Cowan P, Farrar JT, Haddox JD, Haythornthwaite JA, Hertz S, Jay GW, Johanson CE, Junor R, Katz NP, Klein M, Kopecky EA, Leiderman DB, McDermott MP, O'Brien C, O'Connor AB, Palmer PP, Raja SN, Rappaport BA, Rauschkolb C, Rowbotham MC, Sampaio C, Setnik B, Sokolowska M, Stauffer JW, Walsh SL.

Pain. 2012 Dec;153(12):2315-24. doi: 10.1016/j.pain.2012.07.035. Epub 2012 Sep 19.


Adherence to CONSORT harms-reporting recommendations in publications of recent analgesic clinical trials: an ACTTION systematic review.

Smith SM, Chang RD, Pereira A, Shah N, Gilron I, Katz NP, Lin AH, McDermott MP, Rappaport BA, Rowbotham MC, Sampaio C, Turk DC, Dworkin RH.

Pain. 2012 Dec;153(12):2415-21. doi: 10.1016/j.pain.2012.08.009. Epub 2012 Sep 15. Review.


A snapshot and scorecard for analgesic clinical trials for chronic pain: the RReACT database.

Greene K, Dworkin RH, Rowbotham MC.

Pain. 2012 Sep;153(9):1794-7. doi: 10.1016/j.pain.2012.06.004. Epub 2012 Jul 15. Review. No abstract available.


Randomized control trial of topical clonidine for treatment of painful diabetic neuropathy.

Campbell CM, Kipnes MS, Stouch BC, Brady KL, Kelly M, Schmidt WK, Petersen KL, Rowbotham MC, Campbell JN.

Pain. 2012 Sep;153(9):1815-23. doi: 10.1016/j.pain.2012.04.014. Epub 2012 Jun 8.


Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations.

Dworkin RH, Turk DC, Peirce-Sandner S, Burke LB, Farrar JT, Gilron I, Jensen MP, Katz NP, Raja SN, Rappaport BA, Rowbotham MC, Backonja MM, Baron R, Bellamy N, Bhagwagar Z, Costello A, Cowan P, Fang WC, Hertz S, Jay GW, Junor R, Kerns RD, Kerwin R, Kopecky EA, Lissin D, Malamut R, Markman JD, McDermott MP, Munera C, Porter L, Rauschkolb C, Rice AS, Sampaio C, Skljarevski V, Sommerville K, Stacey BR, Steigerwald I, Tobias J, Trentacosti AM, Wasan AD, Wells GA, Williams J, Witter J, Ziegler D.

Pain. 2012 Jun;153(6):1148-58. doi: 10.1016/j.pain.2012.03.003. Epub 2012 Apr 9.


Efficacy and safety of the α4β2 neuronal nicotinic receptor agonist ABT-894 in patients with diabetic peripheral neuropathic pain.

Rowbotham MC, Arslanian A, Nothaft W, Duan WR, Best AE, Pritchett Y, Zhou Q, Stacey BR.

Pain. 2012 Apr;153(4):862-8. doi: 10.1016/j.pain.2012.01.009. Epub 2012 Mar 3.


How to reduce the incidence of neuropathic pain: sentinel node biopsy for diagnosis of metastatic malignant melanoma.

Rowbotham MC, Leong SP.

Pain. 2011 Dec;152(12):2681-2. doi: 10.1016/j.pain.2011.09.006. Epub 2011 Oct 7. No abstract available.


Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial.

Rowbotham MC, Nothaft W, Duan WR, Wang Y, Faltynek C, McGaraughty S, Chu KL, Svensson P.

Pain. 2011 May;152(5):1192-200. doi: 10.1016/j.pain.2011.01.051. Epub 2011 Mar 4.


Effect of a single dose of pregabalin on herpes zoster pain.

Jensen-Dahm C, Rowbotham MC, Reda H, Petersen KL.

Trials. 2011 Feb 28;12:55. doi: 10.1186/1745-6215-12-55.


Evidence-based clinical trial design for chronic pain pharmacotherapy: a blueprint for ACTION.

Dworkin RH, Turk DC, Katz NP, Rowbotham MC, Peirce-Sandner S, Cerny I, Clingman CS, Eloff BC, Farrar JT, Kamp C, McDermott MP, Rappaport BA, Sanhai WR.

Pain. 2011 Mar;152(3 Suppl):S107-15. doi: 10.1016/j.pain.2010.11.008. Epub 2010 Dec 9. Review. No abstract available.


Natural history of cutaneous innervation following herpes zoster.

Petersen KL, Rice FL, Farhadi M, Reda H, Rowbotham MC.

Pain. 2010 Jul;150(1):75-82. doi: 10.1016/j.pain.2010.04.002. Epub 2010 May 8.


Natural history of sensory function after herpes zoster.

Petersen KL, Rowbotham MC.

Pain. 2010 Jul;150(1):83-92. doi: 10.1016/j.pain.2010.04.005. Epub 2010 May 7.


Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base.

Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham MC, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM.

J Pain. 2010 Sep;11(9):807-29. doi: 10.1016/j.jpain.2010.02.019. Epub 2010 Apr 28.


Pain's policy on the spinal administration of drugs.

Rowbotham MC.

Pain. 2010 Jun;149(3):415-6. doi: 10.1016/j.pain.2010.02.027. Epub 2010 Mar 3. No abstract available.


The case for publishing 'negative' clinical trials.

Rowbotham MC.

Pain. 2009 Dec;146(3):225-6. doi: 10.1016/j.pain.2009.09.026. Epub 2009 Oct 22. No abstract available.


Clinical effectiveness: an approach to clinical trial design more relevant to clinical practice, acknowledging the importance of individual differences.

Moore RA, Derry S, McQuay HJ, Straube S, Aldington D, Wiffen P, Bell RF, Kalso E, Rowbotham MC; ACTINPAIN writing group of the IASP Special Interest Group (SIG) on Systematic Reviews in Pain Relief.

Pain. 2010 May;149(2):173-6. doi: 10.1016/j.pain.2009.08.007. Epub 2009 Sep 11. Review. No abstract available.


A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain.

Rowbotham MC, Duan WR, Thomas J, Nothaft W, Backonja MM.

Pain. 2009 Dec;146(3):245-52. doi: 10.1016/j.pain.2009.06.013. Epub 2009 Jul 24.


The impact of selective publication on clinical research in pain.

Rowbotham MC.

Pain. 2008 Dec;140(3):401-4. doi: 10.1016/j.pain.2008.10.026. Epub 2008 Nov 11. Review. No abstract available.


Naltrexone aversion and treatment efficacy are greatest in humans and rats that actively consume high levels of alcohol.

Mitchell JM, Bergren LJ, Chen KS, Rowbotham MC, Fields HL.

Neurobiol Dis. 2009 Jan;33(1):72-80. doi: 10.1016/j.nbd.2008.09.018. Epub 2008 Oct 1.


How should treatment results from clinical practice be reported?

Rowbotham MC.

Pain. 2008 Sep 15;138(3):475-6. doi: 10.1016/j.pain.2008.08.003. Epub 2008 Aug 22. No abstract available.


Placebo response in neuropathic pain trials.

Quessy SN, Rowbotham MC.

Pain. 2008 Sep 15;138(3):479-83. doi: 10.1016/j.pain.2008.06.024. Epub 2008 Aug 15. Review. No abstract available.


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