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Items: 1 to 50 of 97

1.

Permissive versus restrictive temperature thresholds in critically ill children with fever and infection: a multicentre randomized clinical pilot trial.

Peters MJ, Woolfall K, Khan I, Deja E, Mouncey PR, Wulff J, Mason A, Agbeko RS, Draper ES, Fenn B, Gould DW, Koelewyn A, Klein N, Mackerness C, Martin S, O'Neill L, Ray S, Ramnarayan P, Tibby S, Thorburn K, Tume L, Watkins J, Wellman P, Harrison DA, Rowan KM; FEVER Investigators on behalf of the Paediatric Intensive Care Society Study Group (PICS-SG).

Crit Care. 2019 Mar 7;23(1):69. doi: 10.1186/s13054-019-2354-4.

2.

To Enjoy the FRUIT of Your Labors, Don't Forget to Look before You Leap!

Fan E, Rowan KM.

Ann Am Thorac Soc. 2019 Mar;16(3):309-310. doi: 10.1513/AnnalsATS.201811-814ED. No abstract available.

PMID:
30821490
3.

Different temperature thresholds for antipyretic intervention in critically ill children with fever due to infection: the FEVER feasibility RCT.

Peters MJ, Khan I, Woolfall K, Deja E, Mouncey PR, Wulff J, Mason A, Agbeko R, Draper ES, Fenn B, Gould DW, Koelewyn A, Klein N, Mackerness C, Martin S, O'Neill L, Ramnarayan P, Tibby S, Tume L, Watkins J, Thorburn K, Wellman P, Harrison DA, Rowan KM.

Health Technol Assess. 2019 Feb;23(5):1-148. doi: 10.3310/hta23050.

4.

Effect of a Nurse-Led Preventive Psychological Intervention on Symptoms of Posttraumatic Stress Disorder Among Critically Ill Patients: A Randomized Clinical Trial.

Wade DM, Mouncey PR, Richards-Belle A, Wulff J, Harrison DA, Sadique MZ, Grieve RD, Emerson LM, Mason AJ, Aaronovitch D, Als N, Brewin CR, Harvey SE, Howell DCJ, Hudson N, Mythen MG, Smyth D, Weinman J, Welch J, Whitman C, Rowan KM; POPPI Trial Investigators.

JAMA. 2019 Feb 19;321(7):665-675. doi: 10.1001/jama.2019.0073.

PMID:
30776295
5.

Analysis of Benefit of Intensive Care Unit Transfer for Deteriorating Ward Patients: A Patient-Centered Approach to Clinical Evaluation.

Grieve R, O'Neill S, Basu A, Keele L, Rowan KM, Harris S.

JAMA Netw Open. 2019 Feb 1;2(2):e187704. doi: 10.1001/jamanetworkopen.2018.7704.

PMID:
30768190
6.

ICU Structure and Outcomes Following Traumatic Brain Injury.

Menon DK, Rowan KM, Harrison DA.

Crit Care Med. 2019 Jan;47(1):e68-e69. doi: 10.1097/CCM.0000000000003386. No abstract available.

PMID:
30557260
7.

Psychological outcomes following a nurse-led preventative psychological intervention for critically ill patients trial: Statistical and health economic analysis plan.

Wulff J, Sadique Z, Grieve R, Howell D, Mouncey P, Wade D, Rowan KM, Harrison DA.

J Intensive Care Soc. 2018 Nov;19(4):281-286. doi: 10.1177/1751143718755016. Epub 2018 Jan 29.

8.

A Comparison of Mortality From Sepsis in Brazil and England: The Impact of Heterogeneity in General and Sepsis-Specific Patient Characteristics.

Ranzani OT, Shankar-Hari M, Harrison DA, Rabello LS, Salluh JIF, Rowan KM, Soares M.

Crit Care Med. 2019 Jan;47(1):76-84. doi: 10.1097/CCM.0000000000003438.

PMID:
30247269
9.

Restricted fluid bolus versus current practice in children with septic shock: the FiSh feasibility study and pilot RCT.

Inwald D, Canter RR, Woolfall K, O'Hara CB, Mouncey PR, Zenasni Z, Hudson N, Saunders S, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM.

Health Technol Assess. 2018 Sep;22(51):1-106. doi: 10.3310/hta22510.

10.

Effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route for critically ill adult patients.

Sadique Z, Harrison DA, Bear DE, Rowan KM, Grieve R; CALORIES trial investigators.

J Crit Care. 2018 Aug 26. pii: S0883-9441(18)30351-4. doi: 10.1016/j.jcrc.2018.08.025. [Epub ahead of print] No abstract available.

PMID:
30224150
11.

A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol.

Young PJ, Bagshaw SM, Forbes A, Nichol A, Wright SE, Bellomo R, Bailey MJ, Beasley RW, Eastwood GM, Festa M, Gattas D, van Haren F, Litton E, Mouncey PR, Navarra L, Pilcher D, Mackle DM, McArthur CJ, McGuinness SP, Saxena MK, Webb S, Rowan KM; Australian and New Zealand Intensive Care Society Clinical Trials Group on behalf of the PEPTIC investigators.

Crit Care Resusc. 2018 Sep;20(3):182-189.

PMID:
30153780
12.

Assessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit: A Multicenter Population-Based Cohort Study.

Stelfox HT, Soo A, Niven DJ, Fiest KM, Wunsch H, Rowan KM, Bagshaw SM.

JAMA Intern Med. 2018 Oct 1;178(10):1390-1399. doi: 10.1001/jamainternmed.2018.3675.

PMID:
30128550
13.

Restricted fluid bolus volume in early septic shock: results of the Fluids in Shock pilot trial.

Inwald DP, Canter R, Woolfall K, Mouncey P, Zenasni Z, O'Hara C, Carter A, Jones N, Lyttle MD, Nadel S, Peters MJ, Harrison DA, Rowan KM; PERUKI (Paediatric Emergency Research in the UK and Ireland) and PICS SG (Paediatric Intensive Care Society Study Group).

Arch Dis Child. 2018 Aug 7. pii: archdischild-2018-314924. doi: 10.1136/archdischild-2018-314924. [Epub ahead of print]

14.

Providing psychological support to people in intensive care: development and feasibility study of a nurse-led intervention to prevent acute stress and long-term morbidity.

Wade D, Als N, Bell V, Brewin C, D'Antoni D, Harrison DA, Harvey M, Harvey S, Howell D, Mouncey PR, Mythen M, Richards-Belle A, Smyth D, Weinman J, Welch J, Whitman C, Rowan KM; POPPI investigators.

BMJ Open. 2018 Jul 23;8(7):e021083. doi: 10.1136/bmjopen-2017-021083.

15.

Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.

Peters MJ, Jones GAL, Wiley D, Wulff J, Ramnarayan P, Ray S, Inwald D, Grocott M, Griksaitis M, Pappachan J, O'Neill L, Eaton S, Mouncey PR, Harrison DA, Rowan KM; Oxy-PICU Investigators for the Paediatric Intensive Care Society Study Group (PICS-SG).

Intensive Care Med. 2018 Aug;44(8):1240-1248. doi: 10.1007/s00134-018-5232-7. Epub 2018 Jun 4.

PMID:
29868973
16.

The organisation of critical care for burn patients in the UK: epidemiology and comparison of mortality prediction models.

Toft-Petersen AP, Ferrando-Vivas P, Harrison DA, Dunn K, Rowan KM.

Anaesthesia. 2018 Sep;73(9):1131-1140. doi: 10.1111/anae.14319. Epub 2018 May 15.

PMID:
29762869
17.

Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention.

Richards-Belle A, Mouncey PR, Wade D, Brewin CR, Emerson LM, Grieve R, Harrison DA, Harvey S, Howell D, Mythen M, Sadique Z, Smyth D, Weinman J, Welch J, Rowan KM; POPPI Trial Investigators.

BMJ Open. 2018 Feb 8;8(2):e020908. doi: 10.1136/bmjopen-2017-020908.

18.

Estimating attributable fraction of mortality from sepsis to inform clinical trials.

Shankar-Hari M, Harrison DA, Rowan KM, Rubenfeld GD.

J Crit Care. 2018 Jun;45:33-39. doi: 10.1016/j.jcrc.2018.01.018. Epub 2018 Jan 31.

PMID:
29413720
19.

Protocol for a randomised pilot multiple centre trial of conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU).

Jones GAL, Ramnarayan P, Raman S, Inwald D, Grocott MPW, Eaton S, Ray S, Griksaitis MJ, Pappachan J, Wiley D, Mouncey PR, Wulff J, Harrison DA, Rowan KM, Peters MJ; Oxy-PICU Investigators for thePaediatric Intensive Care Society-Study Group (PICS-SG).

BMJ Open. 2017 Dec 14;7(12):e019253. doi: 10.1136/bmjopen-2017-019253.

20.

Exploring the impact of using measured or estimated values for height and weight on the relationship between BMI and acute hospital mortality.

Toft-Petersen AP, Wulff J, Harrison DA, Ostermann M, Margarson M, Rowan KM, Dawson D.

J Crit Care. 2018 Apr;44:196-202. doi: 10.1016/j.jcrc.2017.11.021. Epub 2017 Nov 15.

PMID:
29156253
21.

A qualitative feasibility study to inform a randomised controlled trial of fluid bolus therapy in septic shock.

O'Hara CB, Canter RR, Mouncey PR, Carter A, Jones N, Nadel S, Peters MJ, Lyttle MD, Harrison DA, Rowan KM, Inwald D, Woolfall K.

Arch Dis Child. 2018 Jan;103(1):28-32. doi: 10.1136/archdischild-2016-312515. Epub 2017 Aug 28.

22.

Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis.

PRISM Investigators, Rowan KM, Angus DC, Bailey M, Barnato AE, Bellomo R, Canter RR, Coats TJ, Delaney A, Gimbel E, Grieve RD, Harrison DA, Higgins AM, Howe B, Huang DT, Kellum JA, Mouncey PR, Music E, Peake SL, Pike F, Reade MC, Sadique MZ, Singer M, Yealy DM.

N Engl J Med. 2017 Jun 8;376(23):2223-2234. doi: 10.1056/NEJMoa1701380. Epub 2017 Mar 21.

23.

Association of Intensive Care Unit Patient-to-Intensivist Ratios With Hospital Mortality.

Gershengorn HB, Harrison DA, Garland A, Wilcox ME, Rowan KM, Wunsch H.

JAMA Intern Med. 2017 Mar 1;177(3):388-396. doi: 10.1001/jamainternmed.2016.8457.

PMID:
28118657
24.

qSOFA for Identifying Sepsis Among Patients With Infection.

Lamontagne F, Harrison DA, Rowan KM.

JAMA. 2017 Jan 17;317(3):267-268. doi: 10.1001/jama.2016.19684. No abstract available.

PMID:
28114531
25.

Psychometric assessment of the Family Satisfaction in the Intensive Care Unit questionnaire in the United Kingdom.

Harrison DA, Ferrando-Vivas P, Wright SE, McColl E, Heyland DK, Rowan KM; Family-Reported Experiences Evaluation Study Investigators.

J Crit Care. 2017 Apr;38:346-350. doi: 10.1016/j.jcrc.2016.10.023. Epub 2016 Nov 5.

PMID:
27914907
26.

Development and validation of the new ICNARC model for prediction of acute hospital mortality in adult critical care.

Ferrando-Vivas P, Jones A, Rowan KM, Harrison DA.

J Crit Care. 2017 Apr;38:335-339. doi: 10.1016/j.jcrc.2016.11.031. Epub 2016 Nov 21.

PMID:
27899205
27.

The Assessment of Risk in Cardiothoracic Intensive Care (ARCtIC): prediction of hospital mortality after admission to cardiothoracic critical care.

Shahin J, Ferrando-Vivas P, Power GS, Biswas S, Webb ST, Rowan KM, Harrison DA.

Anaesthesia. 2016 Dec;71(12):1410-1416. doi: 10.1111/anae.13624. Epub 2016 Sep 26.

28.

Predicting invasive fungal disease due to Candida species in non-neutropenic, critically ill, adult patients in United Kingdom critical care units.

Shahin J, Allen EJ, Patel K, Muskett H, Harvey SE, Edgeworth J, Kibbler CC, Barnes RA, Biswas S, Soni N, Rowan KM, Harrison DA; FIRE Study Investigators.

BMC Infect Dis. 2016 Sep 9;16:480. doi: 10.1186/s12879-016-1803-9.

30.

An evaluation of the clinical and cost-effectiveness of alternative care locations for critically ill adult patients with acute traumatic brain injury.

Grieve R, Sadique Z, Gomes M, Smith M, Lecky FE, Hutchinson PJ, Menon DK, Rowan KM, Harrison DA; Risk Adjustment In Neurocritical care (RAIN) Study Investigators.

Br J Neurosurg. 2016 Aug;30(4):388-96. doi: 10.3109/02688697.2016.1161166. Epub 2016 May 18.

PMID:
27188663
31.

A multicentre, randomised controlled trial comparing the clinical effectiveness and cost-effectiveness of early nutritional support via the parenteral versus the enteral route in critically ill patients (CALORIES).

Harvey SE, Parrott F, Harrison DA, Sadique MZ, Grieve RD, Canter RR, McLennan BK, Tan JC, Bear DE, Segaran E, Beale R, Bellingan G, Leonard R, Mythen MG, Rowan KM.

Health Technol Assess. 2016 Apr;20(28):1-144. doi: 10.3310/hta20280.

32.

Five-Year Mortality and Hospital Costs Associated with Surviving Intensive Care.

Lone NI, Gillies MA, Haddow C, Dobbie R, Rowan KM, Wild SH, Murray GD, Walsh TS.

Am J Respir Crit Care Med. 2016 Jul 15;194(2):198-208. doi: 10.1164/rccm.201511-2234OC.

33.

Family-Reported Experiences Evaluation (FREE) study: a mixed-methods study to evaluate families’ satisfaction with adult critical care services in the NHS.

Wright SE, Walmsley E, Harvey SE, Robinson E, Ferrando-Vivas P, Harrison DA, Canter RR, McColl E, Richardson A, Richardson M, Hinton L, Heyland DK, Rowan KM.

Southampton (UK): NIHR Journals Library; 2015 Dec.

34.

Cost-effectiveness of a cardiac output-guided haemodynamic therapy algorithm in high-risk patients undergoing major gastrointestinal surgery.

Sadique Z, Harrison DA, Grieve R, Rowan KM, Pearse RM; OPTIMISE study group.

Perioper Med (Lond). 2015 Dec 14;4:13. doi: 10.1186/s13741-015-0024-x. eCollection 2015.

35.

Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study.

Robinson EJ, Smith GB, Power GS, Harrison DA, Nolan J, Soar J, Spearpoint K, Gwinnutt C, Rowan KM.

BMJ Qual Saf. 2016 Nov;25(11):832-841. doi: 10.1136/bmjqs-2015-004223. Epub 2015 Dec 11.

36.

Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised resuscitation for emerging septic shock.

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Tan JC, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM.

Health Technol Assess. 2015 Nov;19(97):i-xxv, 1-150. doi: 10.3310/hta19970.

37.
38.

Regional variation in critical care provision and outcome after high-risk surgery.

Gillies MA, Power GS, Harrison DA, Fleming A, Cook B, Walsh TS, Pearse RM, Rowan KM.

Intensive Care Med. 2015 Oct;41(10):1809-16. doi: 10.1007/s00134-015-3980-1. Epub 2015 Jul 23.

PMID:
26202040
39.

A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators.

Angus DC, Barnato AE, Bell D, Bellomo R, Chong CR, Coats TJ, Davies A, Delaney A, Harrison DA, Holdgate A, Howe B, Huang DT, Iwashyna T, Kellum JA, Peake SL, Pike F, Reade MC, Rowan KM, Singer M, Webb SA, Weissfeld LA, Yealy DM, Young JD.

Intensive Care Med. 2015 Sep;41(9):1549-60. doi: 10.1007/s00134-015-3822-1. Epub 2015 May 8. Review.

PMID:
25952825
40.

External Validation and Recalibration of Risk Prediction Models for Acute Traumatic Brain Injury among Critically Ill Adult Patients in the United Kingdom.

Harrison DA, Griggs KA, Prabhu G, Gomes M, Lecky FE, Hutchinson PJ, Menon DK, Rowan KM; Risk Adjustment In Neurocritical care (RAIN) Study Investigators.

J Neurotrauma. 2015 Oct 1;32(19):1522-37. doi: 10.1089/neu.2014.3628. Epub 2015 Jun 12.

41.

Trial of early, goal-directed resuscitation for septic shock.

Mouncey PR, Osborn TM, Power GS, Harrison DA, Sadique MZ, Grieve RD, Jahan R, Harvey SE, Bell D, Bion JF, Coats TJ, Singer M, Young JD, Rowan KM; ProMISe Trial Investigators.

N Engl J Med. 2015 Apr 2;372(14):1301-11. doi: 10.1056/NEJMoa1500896. Epub 2015 Mar 17.

42.

Relationship between patients' outcomes and the changes in serum creatinine and urine output and RIFLE classification in a large critical care cohort database.

Harris SK, Lewington AJ, Harrison DA, Rowan KM.

Kidney Int. 2015 Aug;88(2):369-77. doi: 10.1038/ki.2015.70. Epub 2015 Mar 11.

PMID:
25760320
43.

Accounting for Heterogeneity in Relative Treatment Effects for Use in Cost-Effectiveness Models and Value-of-Information Analyses.

Welton NJ, Soares MO, Palmer S, Ades AE, Harrison D, Shankar-Hari M, Rowan KM.

Med Decis Making. 2015 Jul;35(5):608-21. doi: 10.1177/0272989X15570113. Epub 2015 Feb 23.

44.

External validation of the Intensive Care National Audit & Research Centre (ICNARC) risk prediction model in critical care units in Scotland.

Harrison DA, Lone NI, Haddow C, MacGillivray M, Khan A, Cook B, Rowan KM.

BMC Anesthesiol. 2014 Dec 15;14:116. doi: 10.1186/1471-2253-14-116. eCollection 2014.

45.

The CALORIES trial: statistical analysis plan.

Harvey SE, Parrott F, Harrison DA, Mythen M, Rowan KM.

Crit Care Resusc. 2014 Dec;16(4):248-54.

PMID:
25437217
46.

Intravenous immunoglobulin for severe sepsis and septic shock: clinical effectiveness, cost-effectiveness and value of a further randomised controlled trial.

Soares MO, Welton NJ, Harrison DA, Peura P, Shankar-Hari M, Harvey SE, Madan J, Ades AE, Rowan KM, Palmer SJ.

Crit Care. 2014 Dec 1;18(6):649. doi: 10.1186/s13054-014-0649-z.

47.

Trial of the route of early nutritional support in critically ill adults.

Harvey SE, Parrott F, Harrison DA, Bear DE, Segaran E, Beale R, Bellingan G, Leonard R, Mythen MG, Rowan KM; CALORIES Trial Investigators.

N Engl J Med. 2014 Oct 30;371(18):1673-84. doi: 10.1056/NEJMoa1409860. Epub 2014 Oct 1.

48.

Comparing mortality among adult, general intensive care units in England with varying intensivist cover patterns: a retrospective cohort study.

Wilcox ME, Harrison DA, Short A, Jonas M, Rowan KM.

Crit Care. 2014 Aug 14;18(4):491. doi: 10.1186/s13054-014-0491-3.

49.

Survival after postoperative morbidity: a longitudinal observational cohort study.

Moonesinghe SR, Harris S, Mythen MG, Rowan KM, Haddad FS, Emberton M, Grocott MP.

Br J Anaesth. 2014 Dec;113(6):977-84. doi: 10.1093/bja/aeu224. Epub 2014 Jul 10.

50.

Development and validation of risk models to predict outcomes following in-hospital cardiac arrest attended by a hospital-based resuscitation team.

Harrison DA, Patel K, Nixon E, Soar J, Smith GB, Gwinnutt C, Nolan JP, Rowan KM; National Cardiac Arrest Audit.

Resuscitation. 2014 Aug;85(8):993-1000. doi: 10.1016/j.resuscitation.2014.05.004. Epub 2014 May 14.

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