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Items: 31

1.

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance.

Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, Sun N, Chen X, Brown D, Rovira II, Taguchi K, Brooks CR, Stillman IE, Bhasin MK, Finkel T, Parikh SM.

JCI Insight. 2019 Mar 14;5. pii: 126749. doi: 10.1172/jci.insight.126749.

2.

Macrophage fatty acid oxidation inhibits atherosclerosis progression.

Nomura M, Liu J, Yu ZX, Yamazaki T, Yan Y, Kawagishi H, Rovira II, Liu C, Wolfgang MJ, Mukouyama YS, Finkel T.

J Mol Cell Cardiol. 2019 Feb;127:270-276. doi: 10.1016/j.yjmcc.2019.01.003. Epub 2019 Jan 9.

PMID:
30639412
3.

Sonic hedgehog signaling regulates the mammalian cardiac regenerative response.

Kawagishi H, Xiong J, Rovira II, Pan H, Yan Y, Fleischmann BK, Yamada M, Finkel T.

J Mol Cell Cardiol. 2018 Oct;123:180-184. doi: 10.1016/j.yjmcc.2018.09.005. Epub 2018 Sep 17.

PMID:
30236923
4.

A Metabolic Basis for Endothelial-to-Mesenchymal Transition.

Xiong J, Kawagishi H, Yan Y, Liu J, Wells QS, Edmunds LR, Fergusson MM, Yu ZX, Rovira II, Brittain EL, Wolfgang MJ, Jurczak MJ, Fessel JP, Finkel T.

Mol Cell. 2018 Feb 15;69(4):689-698.e7. doi: 10.1016/j.molcel.2018.01.010. Epub 2018 Feb 8.

5.

A fluorescence-based imaging method to measure in vitro and in vivo mitophagy using mt-Keima.

Sun N, Malide D, Liu J, Rovira II, Combs CA, Finkel T.

Nat Protoc. 2017 Aug;12(8):1576-1587. doi: 10.1038/nprot.2017.060. Epub 2017 Jul 13.

PMID:
28703790
6.

The In Vivo Biology of the Mitochondrial Calcium Uniporter.

Liu JC, Parks RJ, Liu J, Stares J, Rovira II, Murphy E, Finkel T.

Adv Exp Med Biol. 2017;982:49-63. doi: 10.1007/978-3-319-55330-6_3. Review.

PMID:
28551781
7.

Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation.

Marmisolle I, Martínez J, Liu J, Mastrogiovanni M, Fergusson MM, Rovira II, Castro L, Trostchansky A, Moreno M, Cao L, Finkel T, Quijano C.

Arch Biochem Biophys. 2017 Jan 1;613:12-22. doi: 10.1016/j.abb.2016.10.016. Epub 2016 Oct 27.

8.

Fatty acid oxidation in macrophage polarization.

Nomura M, Liu J, Rovira II, Gonzalez-Hurtado E, Lee J, Wolfgang MJ, Finkel T.

Nat Immunol. 2016 Mar;17(3):216-7. doi: 10.1038/ni.3366. No abstract available.

9.

Measuring In Vivo Mitophagy.

Sun N, Yun J, Liu J, Malide D, Liu C, Rovira II, Holmström KM, Fergusson MM, Yoo YH, Combs CA, Finkel T.

Mol Cell. 2015 Nov 19;60(4):685-96. doi: 10.1016/j.molcel.2015.10.009. Epub 2015 Nov 5.

10.

The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.

Pan X, Liu J, Nguyen T, Liu C, Sun J, Teng Y, Fergusson MM, Rovira II, Allen M, Springer DA, Aponte AM, Gucek M, Balaban RS, Murphy E, Finkel T.

Nat Cell Biol. 2013 Dec;15(12):1464-72. doi: 10.1038/ncb2868. Epub 2013 Nov 10.

11.

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor.

Torisu T, Torisu K, Lee IH, Liu J, Malide D, Combs CA, Wu XS, Rovira II, Fergusson MM, Weigert R, Connelly PS, Daniels MP, Komatsu M, Cao L, Finkel T.

Nat Med. 2013 Oct;19(10):1281-7. doi: 10.1038/nm.3288. Epub 2013 Sep 22.

12.

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression.

Wu JJ, Liu J, Chen EB, Wang JJ, Cao L, Narayan N, Fergusson MM, Rovira II, Allen M, Springer DA, Lago CU, Zhang S, DuBois W, Ward T, deCabo R, Gavrilova O, Mock B, Finkel T.

Cell Rep. 2013 Sep 12;4(5):913-20. doi: 10.1016/j.celrep.2013.07.030. Epub 2013 Aug 29.

13.

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.

Narayan N, Lee IH, Borenstein R, Sun J, Wong R, Tong G, Fergusson MM, Liu J, Rovira II, Cheng HL, Wang G, Gucek M, Lombard D, Alt FW, Sack MN, Murphy E, Cao L, Finkel T.

Nature. 2012 Dec 13;492(7428):199-204. doi: 10.1038/nature11700. Epub 2012 Nov 28. Retraction in: Nature. 2014 Feb 27;506(7489):516.

PMID:
23201684
14.

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress.

Lee IH, Kawai Y, Fergusson MM, Rovira II, Bishop AJ, Motoyama N, Cao L, Finkel T.

Science. 2012 Apr 13;336(6078):225-8. doi: 10.1126/science.1218395. Erratum in: Science. 2012 Aug 24;337(6097):911. Science. 2013 Aug 2;341(6145):457.

15.

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations.

Quijano C, Cao L, Fergusson MM, Romero H, Liu J, Gutkind S, Rovira II, Mohney RP, Karoly ED, Finkel T.

Cell Cycle. 2012 Apr 1;11(7):1383-92. doi: 10.4161/cc.19800. Epub 2012 Apr 1.

16.

BRCA1 is an essential regulator of heart function and survival following myocardial infarction.

Shukla PC, Singh KK, Quan A, Al-Omran M, Teoh H, Lovren F, Cao L, Rovira II, Pan Y, Brezden-Masley C, Yanagawa B, Gupta A, Deng CX, Coles JG, Leong-Poi H, Stanford WL, Parker TG, Schneider MD, Finkel T, Verma S.

Nat Commun. 2011 Dec 20;2:593. doi: 10.1038/ncomms1601.

17.

Wnt signaling regulates hepatic metabolism.

Liu H, Fergusson MM, Wu JJ, Rovira II, Liu J, Gavrilova O, Lu T, Bao J, Han D, Sack MN, Finkel T.

Sci Signal. 2011 Feb 1;4(158):ra6. doi: 10.1126/scisignal.2001249.

18.

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy.

Wu JJ, Quijano C, Chen E, Liu H, Cao L, Fergusson MM, Rovira II, Gutkind S, Daniels MP, Komatsu M, Finkel T.

Aging (Albany NY). 2009 Apr 9;1(4):425-37.

19.

Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules.

Ohtsubo T, Matsumura K, Sakagami K, Fujii K, Tsuruya K, Noguchi H, Rovira II, Finkel T, Iida M.

Hypertension. 2009 Oct;54(4):868-76. doi: 10.1161/HYPERTENSIONAHA.109.135152. Epub 2009 Aug 10.

20.

Bmi1 regulates mitochondrial function and the DNA damage response pathway.

Liu J, Cao L, Chen J, Song S, Lee IH, Quijano C, Liu H, Keyvanfar K, Chen H, Cao LY, Ahn BH, Kumar NG, Rovira II, Xu XL, van Lohuizen M, Motoyama N, Deng CX, Finkel T.

Nature. 2009 May 21;459(7245):387-392. doi: 10.1038/nature08040. Epub 2009 Apr 29.

21.

Augmented Wnt signaling in a mammalian model of accelerated aging.

Liu H, Fergusson MM, Castilho RM, Liu J, Cao L, Chen J, Malide D, Rovira II, Schimel D, Kuo CJ, Gutkind JS, Hwang PM, Finkel T.

Science. 2007 Aug 10;317(5839):803-6.

22.

Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.

Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W, Frank JA, Reitz M, Finkel T.

J Exp Med. 2006 May 15;203(5):1235-47. Epub 2006 Apr 24.

23.

Redox-dependent transcriptional regulation.

Liu H, Colavitti R, Rovira II, Finkel T.

Circ Res. 2005 Nov 11;97(10):967-74. Review.

PMID:
16284189
24.

Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.

Ohtsubo T, Rovira II, Starost MF, Liu C, Finkel T.

Circ Res. 2004 Nov 26;95(11):1118-24. Epub 2004 Nov 4.

PMID:
15528468
25.

Regulation of the Werner helicase through a direct interaction with a subunit of protein kinase A.

Nguyen DT, Rovira II, Finkel T.

FEBS Lett. 2002 Jun 19;521(1-3):170-4.

26.

Oxidants painting the cysteine chapel: redox regulation of PTPs.

Xu D, Rovira II, Finkel T.

Dev Cell. 2002 Mar;2(3):251-2. Review.

27.

Endothelial progenitor cells as putative targets for angiostatin.

Ito H, Rovira II, Bloom ML, Takeda K, Ferrans VJ, Quyyumi AA, Finkel T.

Cancer Res. 1999 Dec 1;59(23):5875-7.

28.

A role for reactive oxygen species in endothelial cell anoikis.

Li AE, Ito H, Rovira II, Kim KS, Takeda K, Yu ZY, Ferrans VJ, Finkel T.

Circ Res. 1999 Aug 20;85(4):304-10.

PMID:
10455058
29.

Regulation of endothelial cell adherens junctions by a Ras-dependent signal transduction pathway.

Hegland DD, Sullivan DM, Rovira II, Li A, Kovesdi I, Bruder JT, Finkel T.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):371-6.

PMID:
10403777
30.

A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.

Pracyk JB, Tanaka K, Hegland DD, Kim KS, Sethi R, Rovira II, Blazina DR, Lee L, Bruder JT, Kovesdi I, Goldshmidt-Clermont PJ, Irani K, Finkel T.

J Clin Invest. 1998 Sep 1;102(5):929-37.

31.

The effect of pyridoxine on the depressant action of ethanol.

Basilio CM, Rovira II, Bernstein J.

P R Health Sci J. 1989 Dec;8(3):301-2. No abstract available.

PMID:
2561796

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