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Study of chromatin remodeling genes implicates SMARCA4 as a putative player in oncogenesis in neuroblastoma.

Bellini A, Bessoltane-Bentahar N, Bhalshankar J, Clement N, Raynal V, Baulande S, Bernard V, Danzon A, Chicard M, Colmet-Daage L, Pierron G, Le Roux L, Planchon JM, Combaret V, Lapouble E, Corradini N, Thebaud E, Gambart M, Valteau-Couanet D, Michon J, Louis-Brennetot C, Janoueix-Lerosey I, Defachelles AS, Bourdeaut F, Delattre O, Schleiermacher G.

Int J Cancer. 2019 Apr 24. doi: 10.1002/ijc.32361. [Epub ahead of print]


Method To Detect Ethanol Vapor in High Humidity by Direct Reflection on a Xerogel Coating.

Dalstein O, Tabo M, Alvarez E, Roux L, Garuz R, Pasquinelli M, Azzi L, Bendahan M, Aguir K, Loizillon J, Abbarchi M, Grosso D.

ACS Appl Mater Interfaces. 2019 Jan 30;11(4):4439-4446. doi: 10.1021/acsami.8b20479. Epub 2019 Jan 18.


Metal chelators for the inhibition of the lymphocytic choriomeningitis virus endonuclease domain.

Saez-Ayala M, Laban Yekwa E, Mondielli C, Roux L, Hernández S, Bailly F, Cotelle P, Rogolino D, Canard B, Ferron F, Alvarez K.

Antiviral Res. 2019 Feb;162:79-89. doi: 10.1016/j.antiviral.2018.12.008. Epub 2018 Dec 14.


Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways.

Osborn MF, Coles AH, Biscans A, Haraszti RA, Roux L, Davis S, Ly S, Echeverria D, Hassler MR, Godinho BMDC, Nikan M, Khvorova A.

Nucleic Acids Res. 2018 Dec 8. doi: 10.1093/nar/gky1232. [Epub ahead of print]


RNAi modulation of placental sFLT1 for the treatment of preeclampsia.

Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, Zsengeller ZK, Hennessy A, Karumanchi SA, Moore MJ, Khvorova A.

Nat Biotechnol. 2018 Nov 19. doi: 10.1038/nbt.4297. [Epub ahead of print]


Identification of Lynch syndrome risk variants in the Romanian population.

Iordache PD, Mates D, Gunnarsson B, Eggertsson HP, Sulem P, Benonisdottir S, Csiki IE, Rascu S, Radavoi D, Ursu R, Staicu C, Calota V, Voinoiu A, Jinga M, Rosoga G, Danau R, Sima SC, Badescu D, Suciu N, Radoi V, Mates IN, Dobra M, Nicolae C, Kristjansdottir S, Jonasson JG, Manolescu A, Arnadottir G, Jensson B, Jonasdottir A, Sigurdsson A, le Roux L, Johannsdottir H, Rafnar T, Halldorsson BV, Jinga V, Stefansson K.

J Cell Mol Med. 2018 Dec;22(12):6068-6076. doi: 10.1111/jcmm.13881. Epub 2018 Oct 16.


Outcomes of the amphilimus-eluting polymer-free stent for chronic total occlusion treatment: a multicentre experience.

Maeremans J, Cottens D, Azzalini L, Pereira B, Godino C, Carlino M, Colombo A, Frambach P, Bellini B, Candilio L, Briguori C, Pierri A, Lamers S, Roux L, Duponselle J, Vrolix M, Dens J.

J Cardiovasc Med (Hagerstown). 2018 Oct;19(10):564-570. doi: 10.2459/JCM.0000000000000704.


Bolus quality and food comfortability of model cheeses for the elderly as influenced by their texture.

Lorieau L, Septier C, Laguerre A, Le Roux L, Hazart E, Ligneul A, Famelart MH, Dupont D, Floury J, Feron G, Labouré H.

Food Res Int. 2018 Sep;111:31-38. doi: 10.1016/j.foodres.2018.05.013. Epub 2018 May 8.


Optimized Cholesterol-siRNA Chemistry Improves Productive Loading onto Extracellular Vesicles.

Haraszti RA, Miller R, Didiot MC, Biscans A, Alterman JF, Hassler MR, Roux L, Echeverria D, Sapp E, DiFiglia M, Aronin N, Khvorova A.

Mol Ther. 2018 Aug 1;26(8):1973-1982. doi: 10.1016/j.ymthe.2018.05.024. Epub 2018 Jun 21.


Prognostic value of the high-sensitivity troponin T assay after percutaneous intervention of chronic total occlusions.

Cottens D, Maeremans J, McCutcheon K, Lamers S, Roux L, Duponselle J, Bennett J, Dens J.

J Cardiovasc Med (Hagerstown). 2018 Jul;19(7):366-372. doi: 10.2459/JCM.0000000000000660.


Modeling of Aniridia-Related Keratopathy by CRISPR/Cas9 Genome Editing of Human Limbal Epithelial Cells and Rescue by Recombinant PAX6 Protein.

Roux LN, Petit I, Domart R, Concordet JP, Qu J, Zhou H, Joliot A, Ferrigno O, Aberdam D.

Stem Cells. 2018 Sep;36(9):1421-1429. doi: 10.1002/stem.2858. Epub 2018 Jul 18.


Hydrophobicity of Lipid-Conjugated siRNAs Predicts Productive Loading to Small Extracellular Vesicles.

Biscans A, Haraszti RA, Echeverria D, Miller R, Didiot MC, Nikan M, Roux L, Aronin N, Khvorova A.

Mol Ther. 2018 Jun 6;26(6):1520-1528. doi: 10.1016/j.ymthe.2018.03.019. Epub 2018 Apr 4.


How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy.

Pasquier A, Alais S, Roux L, Thoulouze MI, Alvarez K, Journo C, Dutartre H, Mahieux R.

Front Microbiol. 2018 Mar 13;9:278. doi: 10.3389/fmicb.2018.00278. eCollection 2018.


Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.

Hassler MR, Turanov AA, Alterman JF, Haraszti RA, Coles AH, Osborn MF, Echeverria D, Nikan M, Salomon WE, Roux L, Godinho BMDC, Davis SM, Morrissey DV, Zamore PD, Karumanchi SA, Moore MJ, Aronin N, Khvorova A.

Nucleic Acids Res. 2018 Mar 16;46(5):2185-2196. doi: 10.1093/nar/gky037.


Bioaccessibility of four calcium sources in different whey-based dairy matrices assessed by in vitro digestion.

Lorieau L, Le Roux L, Gaucheron F, Ligneul A, Hazart E, Dupont D, Floury J.

Food Chem. 2018 Apr 15;245:454-462. doi: 10.1016/j.foodchem.2017.10.108. Epub 2017 Oct 21.


Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization Assay.

Godinho BMDC, Gilbert JW, Haraszti RA, Coles AH, Biscans A, Roux L, Nikan M, Echeverria D, Hassler M, Khvorova A.

Nucleic Acid Ther. 2017 Dec;27(6):323-334. doi: 10.1089/nat.2017.0690. Epub 2017 Oct 12.


Social workers' views on pre-trial therapy in cases of child sexual abuse in South Africa.

Fouché A, le Roux LMP.

Child Abuse Negl. 2018 Feb;76:23-33. doi: 10.1016/j.chiabu.2017.09.008. Epub 2017 Oct 7.


5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo.

Haraszti RA, Roux L, Coles AH, Turanov AA, Alterman JF, Echeverria D, Godinho BMDC, Aronin N, Khvorova A.

Nucleic Acids Res. 2017 Jul 27;45(13):7581-7592. doi: 10.1093/nar/gkx507.


Applications of NMR and computational methodologies to study protein dynamics.

Narayanan C, Bafna K, Roux LD, Agarwal PK, Doucet N.

Arch Biochem Biophys. 2017 Aug 15;628:71-80. doi: 10.1016/ Epub 2017 May 5. Review.


Sharp wave ripples during learning stabilize the hippocampal spatial map.

Roux L, Hu B, Eichler R, Stark E, Buzsáki G.

Nat Neurosci. 2017 Jun;20(6):845-853. doi: 10.1038/nn.4543. Epub 2017 Apr 10.


Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast.

Eudes A, Mouille M, Robinson DS, Benites VT, Wang G, Roux L, Tsai YL, Baidoo EE, Chiu TY, Heazlewood JL, Scheller HV, Mukhopadhyay A, Keasling JD, Deutsch S, Loqué D.

Microb Cell Fact. 2016 Nov 21;15(1):198.


Defective interfering genomes and Ebola virus persistence.

Calain P, Roux L, Kolakofsky D.

Lancet. 2016 Aug 13;388(10045):659-60. doi: 10.1016/S0140-6736(16)31272-7. No abstract available.


Ligand Binding Enhances Millisecond Conformational Exchange in Xylanase B2 from Streptomyces lividans.

Gagné D, Narayanan C, Nguyen-Thi N, Roux LD, Bernard DN, Brunzelle JS, Couture JF, Agarwal PK, Doucet N.

Biochemistry. 2016 Aug 2;55(30):4184-96. doi: 10.1021/acs.biochem.6b00130. Epub 2016 Jul 21.


The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa.

Chambonnier G, Roux L, Redelberger D, Fadel F, Filloux A, Sivaneson M, de Bentzmann S, Bordi C.

PLoS Genet. 2016 May 13;12(5):e1006032. doi: 10.1371/journal.pgen.1006032. eCollection 2016 May.


Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP.

Colletier JP, Sliwa M, Gallat FX, Sugahara M, Guillon V, Schirò G, Coquelle N, Woodhouse J, Roux L, Gotthard G, Royant A, Uriarte LM, Ruckebusch C, Joti Y, Byrdin M, Mizohata E, Nango E, Tanaka T, Tono K, Yabashi M, Adam V, Cammarata M, Schlichting I, Bourgeois D, Weik M.

J Phys Chem Lett. 2016 Mar 3;7(5):882-7. doi: 10.1021/acs.jpclett.5b02789. Epub 2016 Feb 25.


A global agenda for electronic injury surveillance: Consensus statement from the Trauma Association of Canada, the Trauma Society of South Africa, and the Panamerican Trauma Society.

Zargaran E, Adolph L, Schuurman N, Roux L, Ramsey D, Simons R, Spence R, Nicol AJ, Navsaria P, Puyana JC, Parry N, Moore L, Aboutanos M, Yanchar N, Razek T, Ball CG, Hameed SM; Trauma Association of Canada; Trauma Society of South Africa; Panamerican Trauma Society.

J Trauma Acute Care Surg. 2016 Jan;80(1):168-70. doi: 10.1097/TA.0000000000000880. No abstract available.


Astroglial Connexin 43 Hemichannels Modulate Olfactory Bulb Slow Oscillations.

Roux L, Madar A, Lacroix MM, Yi C, Benchenane K, Giaume C.

J Neurosci. 2015 Nov 18;35(46):15339-52. doi: 10.1523/JNEUROSCI.0861-15.2015.


Li4Ti5O12/graphene nanoribbons composite as anodes for lithium ion batteries.

Medina PA 4th, Zheng H, Fahlman BD, Annamalai P, Swartbooi A, le Roux L, Mathe MK.

Springerplus. 2015 Oct 26;4:643. doi: 10.1186/s40064-015-1438-0. eCollection 2015.


Habenular CB1 Receptors Control the Expression of Aversive Memories.

Soria-Gómez E, Busquets-Garcia A, Hu F, Mehidi A, Cannich A, Roux L, Louit I, Alonso L, Wiesner T, Georges F, Verrier D, Vincent P, Ferreira G, Luo M, Marsicano G.

Neuron. 2015 Oct 21;88(2):306-13. doi: 10.1016/j.neuron.2015.08.035. Epub 2015 Sep 24.


Local generation of multineuronal spike sequences in the hippocampal CA1 region.

Stark E, Roux L, Eichler R, Buzsáki G.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10521-6. doi: 10.1073/pnas.1508785112. Epub 2015 Aug 3.


Loss-of-function variants in ATM confer risk of gastric cancer.

Helgason H, Rafnar T, Olafsdottir HS, Jonasson JG, Sigurdsson A, Stacey SN, Jonasdottir A, Tryggvadottir L, Alexiusdottir K, Haraldsson A, le Roux L, Gudmundsson J, Johannsdottir H, Oddsson A, Gylfason A, Magnusson OT, Masson G, Jonsson T, Skuladottir H, Gudbjartsson DF, Thorsteinsdottir U, Sulem P, Stefansson K.

Nat Genet. 2015 Aug;47(8):906-10. doi: 10.1038/ng.3342. Epub 2015 Jun 22.


Exploring S1 plasticity and probing S1' subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors.

Revelant G, Al-Lakkis-Wehbe M, Schmitt M, Alavi S, Schmitt C, Roux L, Al-Masri M, Schifano-Faux N, Maiereanu C, Tarnus C, Albrecht S.

Bioorg Med Chem. 2015 Jul 1;23(13):3192-207. doi: 10.1016/j.bmc.2015.04.066. Epub 2015 May 1.


Enzymatic synthesis of acyclic nucleoside thiophosphonate diphosphates: effect of the α-phosphorus configuration on HIV-1 RT activity.

Priet S, Roux L, Saez-Ayala M, Ferron F, Canard B, Alvarez K.

Antiviral Res. 2015 May;117:122-31. doi: 10.1016/j.antiviral.2015.03.003. Epub 2015 Mar 9.


Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes.

Abudara V, Roux L, Dallérac G, Matias I, Dulong J, Mothet JP, Rouach N, Giaume C.

Glia. 2015 May;63(5):795-811. doi: 10.1002/glia.22785. Epub 2015 Jan 30.


Sendai virus particle production: a more detailed role of F and HN through, namely, their association with M.

Shevtsova-Horoz A, Essaidi-Laziosi M, Roux L.

Virus Res. 2015 Mar 2;199:31-41. doi: 10.1016/j.virusres.2015.01.010. Epub 2015 Jan 19.


Excitation and inhibition compete to control spiking during hippocampal ripples: intracellular study in behaving mice.

English DF, Peyrache A, Stark E, Roux L, Vallentin D, Long MA, Buzsáki G.

J Neurosci. 2014 Dec 3;34(49):16509-17. doi: 10.1523/JNEUROSCI.2600-14.2014.


Tasks for inhibitory interneurons in intact brain circuits.

Roux L, Buzsáki G.

Neuropharmacology. 2015 Jan;88:10-23. doi: 10.1016/j.neuropharm.2014.09.011. Epub 2014 Sep 17. Review.


Skin absorption of six performance amines used in metalworking fluids.

Roux LN, Brooks JD, Yeatts JL, Baynes RE.

J Appl Toxicol. 2015 May;35(5):520-8. doi: 10.1002/jat.3056. Epub 2014 Sep 4.


Differentiation of low-attenuation intracranial hemorrhage and calcification using dual-energy computed tomography in a phantom system.

Nute JL, Le Roux L, Chandler AG, Baladandayuthapani V, Schellingerhout D, Cody DD.

Invest Radiol. 2015 Jan;50(1):9-16. doi: 10.1097/RLI.0000000000000089.


Promiscuity and selectivity in covalent enzyme inhibition: a systematic study of electrophilic fragments.

Jöst C, Nitsche C, Scholz T, Roux L, Klein CD.

J Med Chem. 2014 Sep 25;57(18):7590-9. doi: 10.1021/jm5006918. Epub 2014 Sep 5.


Transmission enhancement through square coaxial aperture arrays in metallic film: when leaky modes filter infrared light for multispectral imaging.

Vial B, Commandré M, Demésy G, Nicolet A, Zolla F, Bedu F, Dallaporta H, Tisserand S, Roux L.

Opt Lett. 2014 Aug 15;39(16):4723-6. doi: 10.1364/OL.39.004723.


Patchwork structure-function analysis of the Sendai virus matrix protein.

Mottet-Osman G, Miazza V, Vidalain PO, Roux L.

Virology. 2014 Sep;464-465:330-340. doi: 10.1016/j.virol.2014.07.024. Epub 2014 Aug 9.


Pyramidal cell-interneuron interactions underlie hippocampal ripple oscillations.

Stark E, Roux L, Eichler R, Senzai Y, Royer S, Buzsáki G.

Neuron. 2014 Jul 16;83(2):467-480. doi: 10.1016/j.neuron.2014.06.023.


Does age modify the cost-effectiveness of community-based physical activity interventions?

Roux L, Pratt M, Lee IM, Bazzarre T, Buchner D.

J Phys Act Health. 2015 Feb;12(2):224-31.


Molecular neuroimaging: the basics.

Le Roux LG, Schellingerhout D.

Semin Roentgenol. 2014 Apr;49(2):225-33. doi: 10.1053/ Epub 2013 Dec 13. Review. No abstract available.


Multispectral band selection and spatial characterization: Application to mitosis detection in breast cancer histopathology.

Irshad H, Gouaillard A, Roux L, Racoceanu D.

Comput Med Imaging Graph. 2014 Jul;38(5):390-402. doi: 10.1016/j.compmedimag.2014.04.003. Epub 2014 Apr 24.


Methods for nuclei detection, segmentation, and classification in digital histopathology: a review-current status and future potential.

Irshad H, Veillard A, Roux L, Racoceanu D.

IEEE Rev Biomed Eng. 2014;7:97-114. doi: 10.1109/RBME.2013.2295804. Review.


In vivo optogenetic identification and manipulation of GABAergic interneuron subtypes.

Roux L, Stark E, Sjulson L, Buzsáki G.

Curr Opin Neurobiol. 2014 Jun;26:88-95. doi: 10.1016/j.conb.2013.12.013. Epub 2014 Jan 14. Review.


Large-scale, high-density (up to 512 channels) recording of local circuits in behaving animals.

Berényi A, Somogyvári Z, Nagy AJ, Roux L, Long JD, Fujisawa S, Stark E, Leonardo A, Harris TD, Buzsáki G.

J Neurophysiol. 2014 Mar;111(5):1132-49. doi: 10.1152/jn.00785.2013. Epub 2013 Dec 18.


Mutation of the TYTLE motif in the cytoplasmic tail of the sendai virus fusion protein deeply affects viral assembly and particle production.

Essaidi-Laziosi M, Shevtsova A, Gerlier D, Roux L.

PLoS One. 2013 Dec 10;8(12):e78074. doi: 10.1371/journal.pone.0078074. eCollection 2013.

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