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Items: 38

1.

Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.

Johnson TB, Mechels K, Anderson RE, Cain JT, Sturdevant DA, Braddock S, Pinz H, Wilson MA, Landsverk M, Roux KJ, Weimer JM.

Sci Rep. 2018 Nov 1;8(1):16161. doi: 10.1038/s41598-018-34437-0.

2.

UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC driven lymphomagenesis in mice.

Hussain S, Bedekovics T, Liu Q, Hu W, Jeon H, Johnson SH, Vasmatzis G, May DG, Roux KJ, Galardy PJ.

Blood. 2018 Sep 26. pii: blood-2018-05-848515. doi: 10.1182/blood-2018-05-848515. [Epub ahead of print]

PMID:
30257881
3.

MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.

Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM.

Mol Neurobiol. 2018 Nov;55(11):8388-8402. doi: 10.1007/s12035-018-0990-3. Epub 2018 Mar 15.

PMID:
29546593
4.

BioID: A Screen for Protein-Protein Interactions.

Roux KJ, Kim DI, Burke B, May DG.

Curr Protoc Protein Sci. 2018 Feb 21;91:19.23.1-19.23.15. doi: 10.1002/cpps.51.

PMID:
29516480
5.

VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF.

Birendra Kc, May DG, Benson BV, Kim DI, Shivega WG, Ali MH, Faustino RS, Campos AR, Roux KJ.

Mol Biol Cell. 2017 Aug 15;28(17):2241-2250. doi: 10.1091/mbc.E17-03-0138. Epub 2017 Jun 21.

6.

Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome.

Cain JT, Kim DI, Quast M, Shivega WG, Patrick RJ, Moser C, Reuter S, Perez M, Myers A, Weimer JM, Roux KJ, Landsverk M.

Am J Med Genet A. 2017 May;173(5):1200-1207. doi: 10.1002/ajmg.a.38162. Epub 2017 Mar 29.

7.

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity.

Alam SG, Zhang Q, Prasad N, Li Y, Chamala S, Kuchibhotla R, Kc B, Aggarwal V, Shrestha S, Jones AL, Levy SE, Roux KJ, Nickerson JA, Lele TP.

Sci Rep. 2016 Dec 1;6:38063. doi: 10.1038/srep38063.

8.

Filling the Void: Proximity-Based Labeling of Proteins in Living Cells.

Kim DI, Roux KJ.

Trends Cell Biol. 2016 Nov;26(11):804-817. doi: 10.1016/j.tcb.2016.09.004. Epub 2016 Sep 22. Review.

9.

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

Forred BJ, Neuharth S, Kim DI, Amolins MW, Motamedchaboki K, Roux KJ, Vitiello PF.

Oxid Med Cell Longev. 2016;2016:5829063. doi: 10.1155/2016/5829063. Epub 2016 Jun 29.

10.

Identifying Protein-Protein Associations at the Nuclear Envelope with BioID.

Kim DI, Jensen SC, Roux KJ.

Methods Mol Biol. 2016;1411:133-46. doi: 10.1007/978-1-4939-3530-7_8.

11.

An improved smaller biotin ligase for BioID proximity labeling.

Kim DI, Jensen SC, Noble KA, Kc B, Roux KH, Motamedchaboki K, Roux KJ.

Mol Biol Cell. 2016 Apr 15;27(8):1188-96. doi: 10.1091/mbc.E15-12-0844. Epub 2016 Feb 24.

12.

BioID Identification of Lamin-Associated Proteins.

Mehus AA, Anderson RH, Roux KJ.

Methods Enzymol. 2016;569:3-22. doi: 10.1016/bs.mie.2015.08.008. Epub 2015 Sep 26.

13.

The nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts.

Alam SG, Lovett D, Kim DI, Roux KJ, Dickinson RB, Lele TP.

J Cell Sci. 2015 May 15;128(10):1901-11. doi: 10.1242/jcs.161703. Epub 2015 Apr 23.

14.

Direct force probe reveals the mechanics of nuclear homeostasis in the mammalian cell.

Neelam S, Chancellor TJ, Li Y, Nickerson JA, Roux KJ, Dickinson RB, Lele TP.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5720-5. doi: 10.1073/pnas.1502111112. Epub 2015 Apr 21.

15.

Making the LINC: SUN and KASH protein interactions.

Kim DI, Birendra KC, Roux KJ.

Biol Chem. 2015 Apr;396(4):295-310. doi: 10.1515/hsz-2014-0267. Review.

16.

Nuclear forces and cell mechanosensing.

Alam S, Lovett DB, Dickinson RB, Roux KJ, Lele TP.

Prog Mol Biol Transl Sci. 2014;126:205-15. doi: 10.1016/B978-0-12-394624-9.00008-7. Review.

17.

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

Kim DI, Birendra KC, Zhu W, Motamedchaboki K, Doye V, Roux KJ.

Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):E2453-61. doi: 10.1073/pnas.1406459111. Epub 2014 Jun 3.

18.

BioID: a screen for protein-protein interactions.

Roux KJ, Kim DI, Burke B.

Curr Protoc Protein Sci. 2013 Nov 5;74:Unit 19.23.. doi: 10.1002/0471140864.ps1923s74.

PMID:
24510646
19.

A mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeleton.

Horn HF, Kim DI, Wright GD, Wong ES, Stewart CL, Burke B, Roux KJ.

J Cell Biol. 2013 Sep 30;202(7):1023-39. doi: 10.1083/jcb.201304004. Epub 2013 Sep 23.

20.

Modulation of Nuclear Shape by Substrate Rigidity.

Lovett DB, Shekhar N, Nickerson JA, Roux KJ, Lele TP.

Cell Mol Bioeng. 2013 Jun 1;6(2):230-238.

21.

Marked by association: techniques for proximity-dependent labeling of proteins in eukaryotic cells.

Roux KJ.

Cell Mol Life Sci. 2013 Oct;70(19):3657-64. doi: 10.1007/s00018-013-1287-3. Epub 2013 Feb 19. Review.

PMID:
23420482
22.

The LINC complex is essential for hearing.

Horn HF, Brownstein Z, Lenz DR, Shivatzki S, Dror AA, Dagan-Rosenfeld O, Friedman LM, Roux KJ, Kozlov S, Jeang KT, Frydman M, Burke B, Stewart CL, Avraham KB.

J Clin Invest. 2013 Feb;123(2):740-50. doi: 10.1172/JCI66911. Epub 2013 Jan 25.

23.

Novel bilobe components in Trypanosoma brucei identified using proximity-dependent biotinylation.

Morriswood B, Havlicek K, Demmel L, Yavuz S, Sealey-Cardona M, Vidilaseris K, Anrather D, Kostan J, Djinovic-Carugo K, Roux KJ, Warren G.

Eukaryot Cell. 2013 Feb;12(2):356-67. doi: 10.1128/EC.00326-12. Epub 2012 Dec 21.

24.

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

Roux KJ, Kim DI, Raida M, Burke B.

J Cell Biol. 2012 Mar 19;196(6):801-10. doi: 10.1083/jcb.201112098. Epub 2012 Mar 12.

25.

The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton.

Lombardi ML, Jaalouk DE, Shanahan CM, Burke B, Roux KJ, Lammerding J.

J Biol Chem. 2011 Jul 29;286(30):26743-53. doi: 10.1074/jbc.M111.233700. Epub 2011 Jun 7.

26.

Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.

Hernandez L, Roux KJ, Wong ES, Mounkes LC, Mutalif R, Navasankari R, Rai B, Cool S, Jeong JW, Wang H, Lee HS, Kozlov S, Grunert M, Keeble T, Jones CM, Meta MD, Young SG, Daar IO, Burke B, Perantoni AO, Stewart CL.

Dev Cell. 2010 Sep 14;19(3):413-25. doi: 10.1016/j.devcel.2010.08.013.

27.

Dynamics of lamin-A processing following precursor accumulation.

Liu Q, Kim DI, Syme J, LuValle P, Burke B, Roux KJ.

PLoS One. 2010 May 28;5(5):e10874. doi: 10.1371/journal.pone.0010874.

28.

Nuclei take a position: managing nuclear location.

Burke B, Roux KJ.

Dev Cell. 2009 Nov;17(5):587-97. doi: 10.1016/j.devcel.2009.10.018. Review.

29.

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization.

Roux KJ, Crisp ML, Liu Q, Kim D, Kozlov S, Stewart CL, Burke B.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2194-9. doi: 10.1073/pnas.0808602106. Epub 2009 Jan 21.

30.

Blurring the boundary: the nuclear envelope extends its reach.

Stewart CL, Roux KJ, Burke B.

Science. 2007 Nov 30;318(5855):1408-12. Review.

PMID:
18048680
31.

Functional association of Sun1 with nuclear pore complexes.

Liu Q, Pante N, Misteli T, Elsagga M, Crisp M, Hodzic D, Burke B, Roux KJ.

J Cell Biol. 2007 Aug 27;178(5):785-98.

32.

From pore to kinetochore and back: regulating envelope assembly.

Roux KJ, Burke B.

Dev Cell. 2006 Sep;11(3):276-8. Review.

33.

Nuclear envelope defects in muscular dystrophy.

Roux KJ, Burke B.

Biochim Biophys Acta. 2007 Feb;1772(2):118-27. Epub 2006 Jun 7. Review.

34.

Molecular alterations resulting from frameshift mutations in peripheral myelin protein 22: implications for neuropathy severity.

Johnson JS, Roux KJ, Fletcher BS, Fortun J, Notterpek L.

J Neurosci Res. 2005 Dec 15;82(6):743-52.

PMID:
16273544
35.

Modulation of epithelial morphology, monolayer permeability, and cell migration by growth arrest specific 3/peripheral myelin protein 22.

Roux KJ, Amici SA, Fletcher BS, Notterpek L.

Mol Biol Cell. 2005 Mar;16(3):1142-51. Epub 2005 Jan 5.

36.
37.

Peripheral myelin protein 22 is a constituent of intercellular junctions in epithelia.

Notterpek L, Roux KJ, Amici SA, Yazdanpour A, Rahner C, Fletcher BS.

Proc Natl Acad Sci U S A. 2001 Dec 4;98(25):14404-9. Epub 2001 Nov 20.

38.

Exon 10b of the NF1 gene represents a mutational hotspot and harbors a recurrent missense mutation Y489C associated with aberrant splicing.

Messiaen LM, Callens T, Roux KJ, Mortier GR, De Paepe A, Abramowicz M, Pericak-Vance MA, Vance JM, Wallace MR.

Genet Med. 1999 Sep-Oct;1(6):248-53.

PMID:
11258625

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