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Segmentation by Classification: A Novel and Reliable Approach for Semi-Automatic Selection of HIV/SIV Envelope Spikes.

Banerjee C, Dutta M, Liu X, Roux KH, Taylor KA.

J Struct Biol. 2019 Nov 13:107426. doi: 10.1016/j.jsb.2019.107426. [Epub ahead of print]


A Case Study of an Effective and Sustainable Antiretroviral Therapy Program in Rural South Africa.

Le Roux KW, Davis EC, Gaunt CB, Young C, Koussa M, Harris C, Rotheram-Borus MJ.

AIDS Patient Care STDS. 2019 Nov;33(11):466-472. doi: 10.1089/apc.2019.0055.


Maternal and child health outcomes in rural South African mothers living with and without HIV.

le Roux KW, Christodoulou J, Davis EC, Stansert Katzen L, Dippenaar E, Tomlinson M, Rotheram-Borus MJ.

AIDS Care. 2019 Oct 22:1-10. doi: 10.1080/09540121.2019.1679706. [Epub ahead of print]


Multimodal imaging for tumour characterization from micro- to macroscopic level using a newly developed dorsal chamber designed for long-term follow-up.

Rouffiac V, Roux KS, Salomé-Desnoulez S, Leguerney I, Ginefri JC, Sébrié C, Jourdain L, Lécluse Y, Laplace-Builhé C.

J Biophotonics. 2019 Oct 8:e201900217. doi: 10.1002/jbio.201900217. [Epub ahead of print]


Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab.

Chaput N, Lepage P, Coutzac C, Soularue E, Le Roux K, Monot C, Boselli L, Routier E, Cassard L, Collins M, Vaysse T, Marthey L, Eggermont A, Asvatourian V, Lanoy E, Mateus C, Robert C, Carbonnel F.

Ann Oncol. 2019 Aug 13. pii: mdz224. doi: 10.1093/annonc/mdz224. [Epub ahead of print] No abstract available.


Mechanical Stabilization of the Glandular Acinus by Linker of Nucleoskeleton and Cytoskeleton Complex.

Zhang Q, Narayanan V, Mui KL, O'Bryan CS, Anderson RH, Kc B, Cabe JI, Denis KB, Antoku S, Roux KJ, Dickinson RB, Angelini TE, Gundersen GG, Conway DE, Lele TP.

Curr Biol. 2019 Sep 9;29(17):2826-2839.e4. doi: 10.1016/j.cub.2019.07.021. Epub 2019 Aug 8.


A Guide for Ex Vivo Handling and Storage of Stool Samples Intended for Fecal Microbiota Transplantation.

Burz SD, Abraham AL, Fonseca F, David O, Chapron A, Béguet-Crespel F, Cénard S, Le Roux K, Patrascu O, Levenez F, Schwintner C, Blottière HM, Béra-Maillet C, Lepage P, Doré J, Juste C.

Sci Rep. 2019 Jun 20;9(1):8897. doi: 10.1038/s41598-019-45173-4.


BioID as a Tool for Protein-Proximity Labeling in Living Cells.

Sears RM, May DG, Roux KJ.

Methods Mol Biol. 2019;2012:299-313. doi: 10.1007/978-1-4939-9546-2_15.


Repair of nuclear ruptures requires barrier-to-autointegration factor.

Halfmann CT, Sears RM, Katiyar A, Busselman BW, Aman LK, Zhang Q, O'Bryan CS, Angelini TE, Lele TP, Roux KJ.

J Cell Biol. 2019 Jul 1;218(7):2136-2149. doi: 10.1083/jcb.201901116. Epub 2019 May 30.


BioID: A Method to Generate a History of Protein Associations.

May DG, Roux KJ.

Methods Mol Biol. 2019;2008:83-95. doi: 10.1007/978-1-4939-9537-0_7. Epub 2019 May 24.


Elimination of dog-mediated human rabies: the burden of human rabies in Africa.

Le Roux K, Kotze J, Perrett K.

Rev Sci Tech. 2018 Aug;37(2):607-615. doi: 10.20506/rst.37.2.2827.


Perinatal maternal depression in rural South Africa: Child outcomes over the first two years.

Christodoulou J, Le Roux K, Tomlinson M, Le Roux IM, Katzen LS, Rotheram-Borus MJ.

J Affect Disord. 2019 Mar 15;247:168-174. doi: 10.1016/j.jad.2019.01.019. Epub 2019 Jan 15.


A longitudinal cohort study of rural adolescent vs adult South African mothers and their children from birth to 24 months.

le Roux K, Christodoulou J, Stansert-Katzen L, Dippenaar E, Laurenzi C, le Roux IM, Tomlinson M, Rotheram-Borus MJ.

BMC Pregnancy Childbirth. 2019 Jan 11;19(1):24. doi: 10.1186/s12884-018-2164-8.


Modulation of the microbiota by oral antibiotics treats immunoglobulin A nephropathy in humanized mice.

Chemouny JM, Gleeson PJ, Abbad L, Lauriero G, Boedec E, Le Roux K, Monot C, Bredel M, Bex-Coudrat J, Sannier A, Daugas E, Vrtovsnik F, Gesualdo L, Leclerc M, Berthelot L, Ben Mkaddem S, Lepage P, Monteiro RC.

Nephrol Dial Transplant. 2019 Jul 1;34(7):1135-1144. doi: 10.1093/ndt/gfy323.


Characterization of a recurrent missense mutation in the forkhead DNA-binding domain of FOXP1.

Johnson TB, Mechels K, Anderson RE, Cain JT, Sturdevant DA, Braddock S, Pinz H, Wilson MA, Landsverk M, Roux KJ, Weimer JM.

Sci Rep. 2018 Nov 1;8(1):16161. doi: 10.1038/s41598-018-34437-0.


UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in mice.

Hussain S, Bedekovics T, Liu Q, Hu W, Jeon H, Johnson SH, Vasmatzis G, May DG, Roux KJ, Galardy PJ.

Blood. 2018 Dec 13;132(24):2564-2574. doi: 10.1182/blood-2018-05-848515. Epub 2018 Sep 26.


Characteristics of owned dogs in rabies endemic KwaZulu-Natal province, South Africa.

Hergert M, Le Roux K, Nel LH.

BMC Vet Res. 2018 Sep 10;14(1):278. doi: 10.1186/s12917-018-1604-z.


Mentor Mothers Zithulele: exploring the role of a peer mentorship program in rural PMTCT care in Zithulele, Eastern Cape, South Africa.

Hamilton ARL, le Roux KWDP, Young CW, Södergård B.

Paediatr Int Child Health. 2018 Aug 13:1-7. doi: 10.1080/20469047.2018.1474697. [Epub ahead of print]


MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.

Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM.

Mol Neurobiol. 2018 Nov;55(11):8388-8402. doi: 10.1007/s12035-018-0990-3. Epub 2018 Mar 15.


BioID: A Screen for Protein-Protein Interactions.

Roux KJ, Kim DI, Burke B, May DG.

Curr Protoc Protein Sci. 2018 Feb 21;91:19.23.1-19.23.15. doi: 10.1002/cpps.51.


Failure to perform assisted deliveries is resulting in an increased neonatal and maternal morbidity and mortality: An expert opinion.

Pattinson RC, Vannevel V, Barnard D, Baloyi S, Gebhardt GS, Le Roux K, Moran N, Moodley J.

S Afr Med J. 2018 Feb 1;108(2):75-78. doi: 10.7196/SAMJ.2017.v108i2.12786.


Effects of processing and storage on almond (Prunus dulcis L.) amandin immunoreactivity.

Su M, Liu C, Roux KH, Gradziel TM, Sathe SK.

Food Res Int. 2017 Oct;100(Pt 1):87-95. doi: 10.1016/j.foodres.2017.06.061. Epub 2017 Jun 27.


Comparison of Laboratory-Developed and Commercial Monoclonal Antibody-Based Sandwich Enzyme-Linked Immunosorbent Assays for Almond (Prunus dulcis) Detection and Quantification.

Liu C, Chhabra GS, Zhao J, Zaffran VD, Gupta S, Roux KH, Gradziel TM, Sathe SK.

J Food Sci. 2017 Oct;82(10):2504-2515. doi: 10.1111/1750-3841.13829. Epub 2017 Sep 4.


Effects of the Maillard Reaction on the Immunoreactivity of Amandin in Food Matrices.

Chhabra GS, Liu C, Su M, Venkatachalam M, Roux KH, Sathe SK.

J Food Sci. 2017 Oct;82(10):2495-2503. doi: 10.1111/1750-3841.13839. Epub 2017 Aug 23.


Identification of a common Ara h 3 epitope recognized by both the capture and the detection monoclonal antibodies in an ELISA detection kit.

Zhao L, Zhao L, Zhang B, Robotham JM, Roux KH, Tang H.

PLoS One. 2017 Aug 11;12(8):e0182935. doi: 10.1371/journal.pone.0182935. eCollection 2017.


To evaluate if increased supervision and support of South African Government health workers' home visits improves maternal and child outcomes: study protocol for a randomized control trial.

Rotheram-Borus MJ, Le Roux K, Le Roux IM, Christodoulou J, Laurenzi C, Mbewu N, Tomlinson M.

Trials. 2017 Aug 7;18(1):368. doi: 10.1186/s13063-017-2074-5.


Elements for optimizing a one-step enzymatic bio-refinery process of shrimp cuticles: Focus on enzymatic proteolysis screening.

Baron R, Socol M, Kaas R, Arhaliass A, Rodriguez Del Pino J, Le Roux K, Donnay-Moreno C, Bergé JP.

Biotechnol Rep (Amst). 2017 Jun 13;15:70-74. doi: 10.1016/j.btre.2017.01.003. eCollection 2017 Sep.


VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF.

Birendra Kc, May DG, Benson BV, Kim DI, Shivega WG, Ali MH, Faustino RS, Campos AR, Roux KJ.

Mol Biol Cell. 2017 Aug 15;28(17):2241-2250. doi: 10.1091/mbc.E17-03-0138. Epub 2017 Jun 21.


A Cherry Seed-Derived Spice, Mahleb, is Recognized by Anti-Almond Antibodies Including Almond-Allergic Patient IgE.

Noble KA, Liu C, Sathe SK, Roux KH.

J Food Sci. 2017 Aug;82(8):1786-1791. doi: 10.1111/1750-3841.13757. Epub 2017 Jun 19.


Structure of Simian Immunodeficiency Virus Envelope Spikes Bound with CD4 and Monoclonal Antibody 36D5.

Hu G, Liu J, Roux KH, Taylor KA.

J Virol. 2017 Jul 27;91(16). pii: e00134-17. doi: 10.1128/JVI.00134-17. Print 2017 Aug 15.


Nonsense pathogenic variants in exon 1 of PHOX2B lead to translational reinitiation in congenital central hypoventilation syndrome.

Cain JT, Kim DI, Quast M, Shivega WG, Patrick RJ, Moser C, Reuter S, Perez M, Myers A, Weimer JM, Roux KJ, Landsverk M.

Am J Med Genet A. 2017 May;173(5):1200-1207. doi: 10.1002/ajmg.a.38162. Epub 2017 Mar 29.


Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab.

Chaput N, Lepage P, Coutzac C, Soularue E, Le Roux K, Monot C, Boselli L, Routier E, Cassard L, Collins M, Vaysse T, Marthey L, Eggermont A, Asvatourian V, Lanoy E, Mateus C, Robert C, Carbonnel F.

Ann Oncol. 2017 Jun 1;28(6):1368-1379. doi: 10.1093/annonc/mdx108.


New isolations of the rabies-related Mokola virus from South Africa.

Coertse J, Markotter W, le Roux K, Stewart D, Sabeta CT, Nel LH.

BMC Vet Res. 2017 Jan 31;13(1):37. doi: 10.1186/s12917-017-0948-0.


Immunisation coverage in the rural Eastern Cape - are we getting the basics of primary care right? Results from a longitudinal prospective cohort study.

Le Roux K, Akin-Olugbade O, Katzen LS, Laurenzi C, Mercer N, Tomlinson M, Rotheram-Borus MJ.

S Afr Med J. 2016 Dec 21;107(1):52-55. doi: 10.7196/SAMJ.2016.v107.i1.11242.


The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity.

Alam SG, Zhang Q, Prasad N, Li Y, Chamala S, Kuchibhotla R, Kc B, Aggarwal V, Shrestha S, Jones AL, Levy SE, Roux KJ, Nickerson JA, Lele TP.

Sci Rep. 2016 Dec 1;6:38063. doi: 10.1038/srep38063.


Filling the Void: Proximity-Based Labeling of Proteins in Living Cells.

Kim DI, Roux KJ.

Trends Cell Biol. 2016 Nov;26(11):804-817. doi: 10.1016/j.tcb.2016.09.004. Epub 2016 Sep 22. Review.


Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

Forred BJ, Neuharth S, Kim DI, Amolins MW, Motamedchaboki K, Roux KJ, Vitiello PF.

Oxid Med Cell Longev. 2016;2016:5829063. doi: 10.1155/2016/5829063. Epub 2016 Jun 29.


Critical and direct involvement of the CD23 stalk region in IgE binding.

Selb R, Eckl-Dorna J, Twaroch TE, Lupinek C, Teufelberger A, Hofer G, Focke-Tejkl M, Gepp B, Linhart B, Breiteneder H, Ellinger A, Keller W, Roux KH, Valenta R, Niederberger V.

J Allergy Clin Immunol. 2017 Jan;139(1):281-289.e5. doi: 10.1016/j.jaci.2016.04.015. Epub 2016 May 7.


Risk factors associated with nonvaccination rabies status of dogs in KwaZulu-Natal, South Africa.

Hergert M, le Roux K, Nel LH.

Vet Med (Auckl). 2016 Jun 27;7:75-83. doi: 10.2147/VMRR.S103859. eCollection 2016.


Nod2 Deficiency Leads to a Specific and Transmissible Mucosa-associated Microbial Dysbiosis Which Is Independent of the Mucosal Barrier Defect.

Al Nabhani Z, Lepage P, Mauny P, Montcuquet N, Roy M, Le Roux K, Dussaillant M, Berrebi D, Hugot JP, Barreau F.

J Crohns Colitis. 2016 Dec;10(12):1428-1436. Epub 2016 May 4.


Identifying Protein-Protein Associations at the Nuclear Envelope with BioID.

Kim DI, Jensen SC, Roux KJ.

Methods Mol Biol. 2016;1411:133-46. doi: 10.1007/978-1-4939-3530-7_8.


Respective Roles of Hematopoietic and Nonhematopoietic Nod2 on the Gut Microbiota and Mucosal Homeostasis.

Alnabhani Z, Hugot JP, Montcuquet N, Le Roux K, Dussaillant M, Roy M, Leclerc M, Cerf-Bensussan N, Lepage P, Barreau F.

Inflamm Bowel Dis. 2016 Apr;22(4):763-73. doi: 10.1097/MIB.0000000000000749.


Overview of the negative ion based neutral beam injectors for ITER.

Schunke B, Boilson D, Chareyre J, Choi CH, Decamps H, El-Ouazzani A, Geli F, Graceffa J, Hemsworth R, Kushwah M, Roux K, Shah D, Singh M, Svensson L, Urbani M.

Rev Sci Instrum. 2016 Feb;87(2):02C101. doi: 10.1063/1.4931802.


Final design of the beam source for the MITICA injector.

Marcuzzi D, Agostinetti P, Dalla Palma M, De Muri M, Chitarin G, Gambetta G, Marconato N, Pasqualotto R, Pavei M, Pilan N, Rizzolo A, Serianni G, Toigo V, Trevisan L, Visentin M, Zaccaria P, Zaupa M, Boilson D, Graceffa J, Hemsworth RS, Choi CH, Marti M, Roux K, Singh MJ, Masiello A, Froeschle M, Heinemann B, Nocentini R, Riedl R, Tobari H, de Esch HP, Muvvala VN.

Rev Sci Instrum. 2016 Feb;87(2):02B309. doi: 10.1063/1.4932615.


An improved smaller biotin ligase for BioID proximity labeling.

Kim DI, Jensen SC, Noble KA, Kc B, Roux KH, Motamedchaboki K, Roux KJ.

Mol Biol Cell. 2016 Apr 15;27(8):1188-96. doi: 10.1091/mbc.E15-12-0844. Epub 2016 Feb 24.


BioID Identification of Lamin-Associated Proteins.

Mehus AA, Anderson RH, Roux KJ.

Methods Enzymol. 2016;569:3-22. doi: 10.1016/bs.mie.2015.08.008. Epub 2015 Sep 26.


IgE epitope proximity determines immune complex shape and effector cell activation capacity.

Gieras A, Linhart B, Roux KH, Dutta M, Khodoun M, Zafred D, Cabauatan CR, Lupinek C, Weber M, Focke-Tejkl M, Keller W, Finkelman FD, Valenta R.

J Allergy Clin Immunol. 2016 May;137(5):1557-65. doi: 10.1016/j.jaci.2015.08.055. Epub 2015 Dec 10.


The Role of Community Health Workers in the Re-Engineering of Primary Health Care in Rural Eastern Cape.

le Roux K, le Roux I, Mbewu N, Davis E.

S Afr Fam Pract (2004). 2015 Mar 1;57(2):116-120.


Fourier Transform Infrared spectroscopy discloses different types of cell death in flow cytometrically sorted cells.

Le Roux K, Prinsloo LC, Meyer D.

Toxicol In Vitro. 2015 Oct;29(7):1932-40. doi: 10.1016/j.tiv.2015.08.002. Epub 2015 Aug 4.


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