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Items: 1 to 50 of 100

1.

The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry.

Kiema TR, Thapa CJ, Laitaoja M, Schmitz W, Maksimainen MM, Fukao T, Rouvinen J, Jänis J, Wierenga RK.

Biochem J. 2019 Jan 25;476(2):307-332. doi: 10.1042/BCJ20180788.

PMID:
30573650
2.

Unraveling Substrate Specificity and Catalytic Promiscuity of Aspergillus oryzae Catechol Oxidase.

Penttinen L, Rutanen C, Jänis J, Rouvinen J, Hakulinen N.

Chembiochem. 2018 Nov 16;19(22):2348-2352. doi: 10.1002/cbic.201800387. Epub 2018 Oct 31.

PMID:
30204291
3.

A new crystal form of Aspergillus oryzae catechol oxidase and evaluation of copper site structures in coupled binuclear copper enzymes.

Penttinen L, Rutanen C, Saloheimo M, Kruus K, Rouvinen J, Hakulinen N.

PLoS One. 2018 May 1;13(5):e0196691. doi: 10.1371/journal.pone.0196691. eCollection 2018.

4.

The crystal structure of D-xylonate dehydratase reveals functional features of enzymes from the Ilv/ED dehydratase family.

Rahman MM, Andberg M, Koivula A, Rouvinen J, Hakulinen N.

Sci Rep. 2018 Jan 16;8(1):865. doi: 10.1038/s41598-018-19192-6.

5.

Insights into the roles of non-catalytic residues in the active site of a GH10 xylanase with activity on cellulose.

Chu Y, Tu T, Penttinen L, Xue X, Wang X, Yi Z, Gong L, Rouvinen J, Luo H, Hakulinen N, Yao B, Su X.

J Biol Chem. 2017 Nov 24;292(47):19315-19327. doi: 10.1074/jbc.M117.807768. Epub 2017 Oct 3.

6.

The Crystal Structure of a Bacterial l-Arabinonate Dehydratase Contains a [2Fe-2S] Cluster.

Rahman MM, Andberg M, Thangaraj SK, Parkkinen T, Penttilä M, Jänis J, Koivula A, Rouvinen J, Hakulinen N.

ACS Chem Biol. 2017 Jul 21;12(7):1919-1927. doi: 10.1021/acschembio.7b00304. Epub 2017 Jun 13.

PMID:
28574691
7.

Identification of Small Molecule Compounds for Pharmacological Chaperone Therapy of Aspartylglucosaminuria.

Banning A, Gülec C, Rouvinen J, Gray SJ, Tikkanen R.

Sci Rep. 2016 Nov 23;6:37583. doi: 10.1038/srep37583.

8.

Crystallization and X-ray diffraction analysis of an L-arabinonate dehydratase from Rhizobium leguminosarum bv. trifolii and a D-xylonate dehydratase from Caulobacter crescentus.

Rahman MM, Andberg M, Koivula A, Rouvinen J, Hakulinen N.

Acta Crystallogr F Struct Biol Commun. 2016 Aug;72(Pt 8):604-8. doi: 10.1107/S2053230X16010311. Epub 2016 Jul 13.

9.

Structural and functional features of the NAD(P) dependent Gfo/Idh/MocA protein family oxidoreductases.

Taberman H, Parkkinen T, Rouvinen J.

Protein Sci. 2016 Apr;25(4):778-86. doi: 10.1002/pro.2877. Epub 2016 Feb 1. Review.

10.

Structure and function of Caulobacter crescentus aldose-aldose oxidoreductase.

Taberman H, Andberg M, Koivula A, Hakulinen N, Penttilä M, Rouvinen J, Parkkinen T.

Biochem J. 2015 Dec 15;472(3):297-307. doi: 10.1042/BJ20150681. Epub 2015 Oct 5.

PMID:
26438878
11.

Dimerization of lipocalin allergens.

Niemi MH, Rytkönen-Nissinen M, Miettinen I, Jänis J, Virtanen T, Rouvinen J.

Sci Rep. 2015 Sep 8;5:13841. doi: 10.1038/srep13841.

12.

Three-dimensional structures of laccases.

Hakulinen N, Rouvinen J.

Cell Mol Life Sci. 2015 Mar;72(5):857-68. doi: 10.1007/s00018-014-1827-5. Epub 2015 Jan 14. Review.

PMID:
25586561
13.

Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk.

Vaarala O, Vuorela A, Partinen M, Baumann M, Freitag TL, Meri S, Saavalainen P, Jauhiainen M, Soliymani R, Kirjavainen T, Olsen P, Saarenpää-Heikkilä O, Rouvinen J, Roivainen M, Nohynek H, Jokinen J, Julkunen I, Kilpi T.

PLoS One. 2014 Dec 15;9(12):e114361. doi: 10.1371/journal.pone.0114361. eCollection 2014.

14.

Structure and function of a decarboxylating Agrobacterium tumefaciens keto-deoxy-d-galactarate dehydratase.

Taberman H, Andberg M, Parkkinen T, Jänis J, Penttilä M, Hakulinen N, Koivula A, Rouvinen J.

Biochemistry. 2014 Dec 30;53(51):8052-60. doi: 10.1021/bi501290k. Epub 2014 Dec 18.

PMID:
25454257
15.

Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.

Niemi MH, Rytkönen-Nissinen M, Jänis J, Virtanen T, Rouvinen J.

Mol Immunol. 2014 Sep;61(1):7-15. doi: 10.1016/j.molimm.2014.04.003. Epub 2014 May 21.

PMID:
24859823
16.

Purification, crystallization and preliminary X-ray diffraction analysis of a novel keto-deoxy-D-galactarate (KDG) dehydratase from Agrobacterium tumefaciens.

Taberman H, Andberg M, Parkkinen T, Richard P, Hakulinen N, Koivula A, Rouvinen J.

Acta Crystallogr F Struct Biol Commun. 2014 Jan;70(Pt 1):49-52. doi: 10.1107/S2053230X13031361. Epub 2013 Dec 24.

17.

The crystal structure of an extracellular catechol oxidase from the ascomycete fungus Aspergillus oryzae.

Hakulinen N, Gasparetti C, Kaljunen H, Kruus K, Rouvinen J.

J Biol Inorg Chem. 2013 Dec;18(8):917-29. doi: 10.1007/s00775-013-1038-9. Epub 2013 Sep 17.

PMID:
24043469
18.

The crystal structure of acidic β-galactosidase from Aspergillus oryzae.

Maksimainen MM, Lampio A, Mertanen M, Turunen O, Rouvinen J.

Int J Biol Macromol. 2013 Sep;60:109-15. doi: 10.1016/j.ijbiomac.2013.05.003. Epub 2013 May 17.

PMID:
23688418
19.

Structural analysis, enzymatic characterization, and catalytic mechanisms of β-galactosidase from Bacillus circulans sp. alkalophilus.

Maksimainen M, Paavilainen S, Hakulinen N, Rouvinen J.

FEBS J. 2012 May;279(10):1788-98. doi: 10.1111/j.1742-4658.2012.08555.x. Epub 2012 Mar 28.

20.

Amphiphilic nanotubes in the crystal structure of a biosurfactant protein hydrophobin HFBII.

Kallio JM, Rouvinen J.

Chem Commun (Camb). 2011 Sep 21;47(35):9843-5. doi: 10.1039/c1cc13139g. Epub 2011 Aug 2.

PMID:
21808803
21.

Crystal structure of uronate dehydrogenase from Agrobacterium tumefaciens.

Parkkinen T, Boer H, Jänis J, Andberg M, Penttilä M, Koivula A, Rouvinen J.

J Biol Chem. 2011 Aug 5;286(31):27294-300. doi: 10.1074/jbc.M111.254854. Epub 2011 Jun 15.

22.

Crystallization and preliminary X-ray analysis of Aspergillus oryzae catechol oxidase.

Kaljunen H, Gasparetti C, Kruus K, Rouvinen J, Hakulinen N.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jun 1;67(Pt 6):672-4. doi: 10.1107/S1744309111010141. Epub 2011 May 25.

23.

Crystal structure of an ascomycete fungal laccase from Thielavia arenaria--common structural features of asco-laccases.

Kallio JP, Gasparetti C, Andberg M, Boer H, Koivula A, Kruus K, Rouvinen J, Hakulinen N.

FEBS J. 2011 Jul;278(13):2283-95. doi: 10.1111/j.1742-4658.2011.08146.x. Epub 2011 May 25.

24.

Probing the dioxygen route in Melanocarpus albomyces laccase with pressurized xenon gas.

Kallio JP, Rouvinen J, Kruus K, Hakulinen N.

Biochemistry. 2011 May 31;50(21):4396-8. doi: 10.1021/bi200486b. Epub 2011 May 5.

PMID:
21524088
25.

The testosterone binding mechanism of an antibody derived from a naïve human scFv library.

Niemi MH, Takkinen K, Amundsen LK, Söderlund H, Rouvinen J, Höyhtyä M.

J Mol Recognit. 2011 Mar-Apr;24(2):209-19. doi: 10.1002/jmr.1039.

PMID:
21360611
26.

Crystal structures of Trichoderma reesei β-galactosidase reveal conformational changes in the active site.

Maksimainen M, Hakulinen N, Kallio JM, Timoharju T, Turunen O, Rouvinen J.

J Struct Biol. 2011 Apr;174(1):156-63. doi: 10.1016/j.jsb.2010.11.024. Epub 2010 Dec 3.

PMID:
21130883
27.

A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection.

Niemi MH, Turunen L, Pulli T, Nevanen TK, Höyhtyä M, Söderlund H, Rouvinen J, Takkinen K.

J Mol Biol. 2010 Jul 23;400(4):803-14. doi: 10.1016/j.jmb.2010.05.048. Epub 2010 May 26.

PMID:
20630472
28.

Transient dimers of allergens.

Rouvinen J, Jänis J, Laukkanen ML, Jylhä S, Niemi M, Päivinen T, Mäkinen-Kiljunen S, Haahtela T, Söderlund H, Takkinen K.

PLoS One. 2010 Feb 5;5(2):e9037. doi: 10.1371/journal.pone.0009037.

29.

Essential role of the C-terminus in Melanocarpus albomyces laccase for enzyme production, catalytic properties and structure.

Andberg M, Hakulinen N, Auer S, Saloheimo M, Koivula A, Rouvinen J, Kruus K.

FEBS J. 2009 Nov;276(21):6285-300. doi: 10.1111/j.1742-4658.2009.07336.x. Epub 2009 Sep 24.

30.

Preliminary X-ray analysis of twinned crystals of sarcosine dimethylglycine methyltransferase from Halorhodospira halochoris.

Kallio JP, Jänis J, Nyyssölä A, Hakulinen N, Rouvinen J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt 8):805-8. doi: 10.1107/S1744309109026232. Epub 2009 Jul 30.

31.

Crystallization and preliminary diffraction analysis of a beta-galactosidase from Trichoderma reesei.

Maksimainen M, Timoharju T, Kallio JM, Hakulinen N, Turunen O, Rouvinen J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1;65(Pt 8):767-9. doi: 10.1107/S1744309109023926. Epub 2009 Jul 25.

32.

Structure-function studies of a Melanocarpus albomyces laccase suggest a pathway for oxidation of phenolic compounds.

Kallio JP, Auer S, Jänis J, Andberg M, Kruus K, Rouvinen J, Koivula A, Hakulinen N.

J Mol Biol. 2009 Oct 2;392(4):895-909. doi: 10.1016/j.jmb.2009.06.053. Epub 2009 Jun 27.

PMID:
19563811
33.

The contribution of polystyrene nanospheres towards the crystallization of proteins.

Kallio JM, Hakulinen N, Kallio JP, Niemi MH, Kärkkäinen S, Rouvinen J.

PLoS One. 2009;4(1):e4198. doi: 10.1371/journal.pone.0004198. Epub 2009 Jan 15.

34.

Crystal structures of Melanocarpus albomyces cellobiohydrolase Cel7B in complex with cello-oligomers show high flexibility in the substrate binding.

Parkkinen T, Koivula A, Vehmaanperä J, Rouvinen J.

Protein Sci. 2008 Aug;17(8):1383-94. doi: 10.1110/ps.034488.108. Epub 2008 May 21.

35.

Characterization of the pH-dependent dissociation of a multimeric metalloprotein Streptomyces rubiginosus xylose isomerase by ESI FT-ICR mass spectrometry.

Jänis J, Pasanen S, Rouvinen J, Vainiotalo P.

J Mass Spectrom. 2008 Oct;43(10):1376-80. doi: 10.1002/jms.1413.

PMID:
18416431
36.

A near atomic resolution structure of a Melanocarpus albomyces laccase.

Hakulinen N, Andberg M, Kallio J, Koivula A, Kruus K, Rouvinen J.

J Struct Biol. 2008 Apr;162(1):29-39. doi: 10.1016/j.jsb.2007.12.003. Epub 2007 Dec 28.

PMID:
18249560
37.

Characterization and crystallization of a recombinant IgE Fab fragment in complex with the bovine beta-lactoglobulin allergen.

Niemi M, Jänis J, Jylhä S, Kallio JM, Hakulinen N, Laukkanen ML, Takkinen K, Rouvinen J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jan 1;64(Pt 1):25-8. Epub 2007 Dec 20.

38.

Animal-derived lipocalin allergens exhibit immunoglobulin E cross-reactivity.

Saarelainen S, Rytkönen-Nissinen M, Rouvinen J, Taivainen A, Auriola S, Kauppinen A, Kinnunen T, Virtanen T.

Clin Exp Allergy. 2008 Feb;38(2):374-81. Epub 2007 Dec 7.

PMID:
18070162
39.

Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen.

Niemi M, Jylhä S, Laukkanen ML, Söderlund H, Mäkinen-Kiljunen S, Kallio JM, Hakulinen N, Haahtela T, Takkinen K, Rouvinen J.

Structure. 2007 Nov;15(11):1413-21.

40.

Irreversible thermal denaturation of Trichoderma reesei endo-1,4-beta-xylanase II and its three disulfide mutants characterized by differential scanning calorimetry.

Jänis J, Rouvinen J, Vainiotalo P, Turunen O, Shnyrov VL.

Int J Biol Macromol. 2008 Jan 1;42(1):75-80. Epub 2007 Sep 29.

PMID:
17988729
41.

Molecular dynamics studies on the thermostability of family 11 xylanases.

Purmonen M, Valjakka J, Takkinen K, Laitinen T, Rouvinen J.

Protein Eng Des Sel. 2007 Nov;20(11):551-9. Epub 2007 Oct 30.

PMID:
17977846
42.

Preliminary X-ray analysis of cellobiohydrolase Cel7B from Melanocarpus albomyces.

Parkkinen T, Koivula A, Vehmaanperä J, Rouvinen J.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Sep 1;63(Pt 9):754-7. Epub 2007 Aug 25.

43.

Crystal structures of hydrophobin HFBII in the presence of detergent implicate the formation of fibrils and monolayer films.

Kallio JM, Linder MB, Rouvinen J.

J Biol Chem. 2007 Sep 28;282(39):28733-9. Epub 2007 Jul 18.

44.

Determination of steady-state kinetic parameters for a xylanase-catalyzed hydrolysis of neutral underivatized xylooligosaccharides by mass spectrometry.

Jänis J, Pulkkinen P, Rouvinen J, Vainiotalo P.

Anal Biochem. 2007 Jun 15;365(2):165-73. Epub 2007 Apr 2.

PMID:
17475200
45.

A crystallographic and spectroscopic study on the effect of X-ray radiation on the crystal structure of Melanocarpus albomyces laccase.

Hakulinen N, Kruus K, Koivula A, Rouvinen J.

Biochem Biophys Res Commun. 2006 Dec 1;350(4):929-34. Epub 2006 Oct 5.

PMID:
17045575
46.

Two crystal structures of Trichoderma reesei hydrophobin HFBI--the structure of a protein amphiphile with and without detergent interaction.

Hakanpää J, Szilvay GR, Kaljunen H, Maksimainen M, Linder M, Rouvinen J.

Protein Sci. 2006 Sep;15(9):2129-40. Epub 2006 Aug 1.

47.

Structure-based stability engineering of the mouse IgG1 Fab fragment by modifying constant domains.

Teerinen T, Valjakka J, Rouvinen J, Takkinen K.

J Mol Biol. 2006 Aug 25;361(4):687-97. Epub 2006 Jul 28.

PMID:
16876195
48.

Hydrophobin HFBII in detail: ultrahigh-resolution structure at 0.75 A.

Hakanpää J, Linder M, Popov A, Schmidt A, Rouvinen J.

Acta Crystallogr D Biol Crystallogr. 2006 Apr;62(Pt 4):356-67. Epub 2006 Mar 18.

PMID:
16552136
49.

Crystal structures of an enantioselective fab-fragment in free and complex forms.

Parkkinen T, Nevanen TK, Koivula A, Rouvinen J.

J Mol Biol. 2006 Mar 24;357(2):471-80. Epub 2006 Jan 3.

PMID:
16427081
50.

Determination of thioxylo-oligosaccharide binding to family 11 xylanases using electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry and X-ray crystallography.

Jänis J, Hakanpää J, Hakulinen N, Ibatullin FM, Hoxha A, Derrick PJ, Rouvinen J, Vainiotalo P.

FEBS J. 2005 May;272(9):2317-33.

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