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UMOD genetic variations and myeloma cast nephropathy.

Belliere J, Faguer S, Huart A, Ribes D, Chassaing N, Roussel M, Chauveau D.

Clin Kidney J. 2019 Jun 15;12(5):639-640. doi: 10.1093/ckj/sfz071. eCollection 2019 Oct. No abstract available.


Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.

Zhang L, He X, Liu X, Zhang F, Huang LF, Potter AS, Xu L, Zhou W, Zheng T, Luo Z, Berry KP, Pribnow A, Smith SM, Fuller C, Jones BV, Fouladi M, Drissi R, Yang ZJ, Gustafson WC, Remke M, Pomeroy SL, Girard EJ, Olson JM, Morrissy AS, Vladoiu MC, Zhang J, Tian W, Xin M, Taylor MD, Potter SS, Roussel MF, Weiss WA, Lu QR.

Cancer Cell. 2019 Sep 16;36(3):302-318.e7. doi: 10.1016/j.ccell.2019.07.009. Epub 2019 Aug 29.


Training program-induced skeletal muscle adaptations in two men with myotonic dystrophy type 1.

Roussel MP, Morin M, Girardin M, Fortin AM, Leone M, Mathieu J, Gagnon C, Duchesne E.

BMC Res Notes. 2019 Aug 20;12(1):526. doi: 10.1186/s13104-019-4554-z.


Women in cancer research.

Mitchell CA, Roussel MF, Walsh L, Weeraratna AT.

Nat Rev Cancer. 2019 Oct;19(10):547-552. doi: 10.1038/s41568-019-0176-y. Epub 2019 Aug 15. Review.


Is Reaction Time Slowing an Early Sign of Alzheimer's Disease? A Meta-Analysis.

Andriuta D, Diouf M, Roussel M, Godefroy O.

Dement Geriatr Cogn Disord. 2019;47(4-6):281-288. doi: 10.1159/000500348. Epub 2019 Aug 13.


MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat.

Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, Mosca R, Campos Y, Tillman H, Roussel MF, Andrew Weesner J, Ellen Fremuth L, Qiu X, Han MJ, Grosveld GC, d'Azzo A.

Nat Commun. 2019 Aug 9;10(1):3623. doi: 10.1038/s41467-019-11568-0.


Standardization of Flow Cytometric Immunophenotyping for Hematological Malignancies: The FranceFlow Group Experience.

Solly F, Angelot-Delettre F, Ticchioni M, Geneviève F, Rambaud H, Baseggio L, Plesa A, Debliquis A, Garnache-Ottou F, Roggy A, Campos L, Aanei C, Rosenthal-Allieri A, Georget MT, Lachot S, Jacob MC, Robillard N, Wuilleme S, Andre-Kerneis E, Cornet E, Salaun V, Bennami H, Lhoumeau AC, Arnoulet C, Jacqmin H, Neyman N, Latger-Cannard V, Massin F, Lainey E, Le Garff-Tavernier M, Costopoulos M, Roussel M, Mayeur-Rousse C, Eischen A, Raggeneau V, Derrieux C, Maurer M, Asnafi V, Trinquand A, Brouzes C, Lhermitte L.

Cytometry A. 2019 Sep;95(9):1008-1018. doi: 10.1002/cyto.a.23844. Epub 2019 Jul 31.


Early-stage myeloid-derived suppressor cell count: Basophil exclusion matters.

Uhel F, Azzaoui I, Le Gallou S, Fest T, Tarte K, Roussel M.

J Allergy Clin Immunol. 2019 Oct;144(4):1125-1127. doi: 10.1016/j.jaci.2019.06.027. Epub 2019 Jul 3. No abstract available.


Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway.

Genthe JR, Min J, Farmer DM, Shelat AA, Grenet JA, Lin W, Finkelstein D, Vrijens K, Chen T, Guy RK, Clements WK, Roussel MF.

ACS Chem Biol. 2019 Jul 19;14(7):1673. doi: 10.1021/acschembio.9b00488. Epub 2019 Jun 28. No abstract available.


Difficulties in emotion regulation and deficits in interoceptive awareness in moderate and severe obesity.

Willem C, Gandolphe MC, Roussel M, Verkindt H, Pattou F, Nandrino JL.

Eat Weight Disord. 2019 Aug;24(4):633-644. doi: 10.1007/s40519-019-00738-0. Epub 2019 Jun 26.


Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study.

Moreau P, Attal M, Hulin C, Arnulf B, Belhadj K, Benboubker L, Béné MC, Broijl A, Caillon H, Caillot D, Corre J, Delforge M, Dejoie T, Doyen C, Facon T, Sonntag C, Fontan J, Garderet L, Jie KS, Karlin L, Kuhnowski F, Lambert J, Leleu X, Lenain P, Macro M, Mathiot C, Orsini-Piocelle F, Perrot A, Stoppa AM, van de Donk NW, Wuilleme S, Zweegman S, Kolb B, Touzeau C, Roussel M, Tiab M, Marolleau JP, Meuleman N, Vekemans MC, Westerman M, Klein SK, Levin MD, Fermand JP, Escoffre-Barbe M, Eveillard JR, Garidi R, Ahmadi T, Zhuang S, Chiu C, Pei L, de Boer C, Smith E, Deraedt W, Kampfenkel T, Schecter J, Vermeulen J, Avet-Loiseau H, Sonneveld P.

Lancet. 2019 Jul 6;394(10192):29-38. doi: 10.1016/S0140-6736(19)31240-1. Epub 2019 Jun 3. Erratum in: Lancet. 2019 Jun 14;:.


Intra-Rater Reliability and Concurrent Validity of Quantified Muscle Testing for Maximal Knee Extensors Strength in Men with Myotonic Dystrophy Type 1.

Roussel MP, Hébert LJ, Duchesne E.

J Neuromuscul Dis. 2019;6(2):233-240. doi: 10.3233/JND-190388.


Correction to: What is known about the effects of exercise or training to reduce skeletal muscle impairments of patients with myotonic dystrophy type 1? A scoping review.

Roussel MP, Morin M, Gagnon C, Duchesne E.

BMC Musculoskelet Disord. 2019 May 24;20(1):244. doi: 10.1186/s12891-019-2643-8.


Picturing Polarized Myeloid Phagocytes and Regulatory Cells by Mass Cytometry.

Roussel M, Bartkowiak T, Irish JM.

Methods Mol Biol. 2019;1989:217-226. doi: 10.1007/978-1-4939-9454-0_14.


Carfilzomib Weekly plus Melphalan and Prednisone in Newly Diagnosed Transplant-Ineligible Multiple Myeloma (IFM 2012-03): A Phase I Trial.

Leleu X, Fouquet G, Richez V, Guidez S, Duhamel A, Machuron F, Karlin L, Kolb B, Tiab M, Araujo C, Meuleman N, Malfuson JV, Bourquard P, Lenain P, Roussel M, Jaccard A, Pétillon MO, Belhadj-Merzoug K, Lepeu G, Chrétien ML, Fontan J, Rodon P, Schmitt A, Offner F, Voillat L, Cereja S, Kuhnowski F, Rigaudeau S, Decaux O, Humbrecht-Kraut C, Frayfer J, Fitoussi O, Roos-Weil D, Eisenmann JC, Dorvaux V, Voog EG, Attal M, Moreau P, Avet-Loiseau H, Hulin C, Facon T.

Clin Cancer Res. 2019 Jul 15;25(14):4224-4230. doi: 10.1158/1078-0432.CCR-18-3642. Epub 2019 May 3.


A Systemic Approach to Complete the Multimodal Assessment Model of Pain.

Lvovschi VE, Roussel M, Dussart C.

Clin J Pain. 2019 Jul;35(7):644-645. doi: 10.1097/AJP.0000000000000715. No abstract available.


Myc and Loss of p53 Cooperate to Drive Formation of Choroid Plexus Carcinoma.

Wang J, Merino DM, Light N, Murphy BL, Wang YD, Guo X, Hodges AP, Chau LQ, Liu KW, Dhall G, Asgharzadeh S, Kiehna EN, Shirey RJ, Janda KD, Taylor MD, Malkin D, Ellison DW, VandenBerg SR, Eberhart CG, Sears RC, Roussel MF, Gilbertson RJ, Wechsler-Reya RJ.

Cancer Res. 2019 May 1;79(9):2208-2219. doi: 10.1158/0008-5472.CAN-18-2565. Epub 2019 Mar 18.


[Multiple myeloma treatment].

Talbot A, Royer B, Roussel M.

Rev Prat. 2018 Sep;68(7):787-791. French.


What is known about the effects of exercise or training to reduce skeletal muscle impairments of patients with myotonic dystrophy type 1? A scoping review.

Roussel MP, Morin M, Gagnon C, Duchesne E.

BMC Musculoskelet Disord. 2019 Mar 5;20(1):101. doi: 10.1186/s12891-019-2458-7. Review. Erratum in: BMC Musculoskelet Disord. 2019 May 24;20(1):244.


Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates.

Cassetta L, Baekkevold ES, Brandau S, Bujko A, Cassatella MA, Dorhoi A, Krieg C, Lin A, Loré K, Marini O, Pollard JW, Roussel M, Scapini P, Umansky V, Adema GJ.

Cancer Immunol Immunother. 2019 Apr;68(4):687-697. doi: 10.1007/s00262-019-02302-2. Epub 2019 Jan 25. Review.


Systematic Review and Meta-Analysis of Prevalence in Post-Stroke Neurocognitive Disorders in Hospital-Based Studies.

Barbay M, Diouf M, Roussel M, Godefroy O; GRECOGVASC study group.

Dement Geriatr Cogn Disord. 2018;46(5-6):322-334. doi: 10.1159/000492920. Epub 2018 Nov 30.


Temporal metabolic partitioning of the yeast and protist cellular networks: the cell is a global scale-invariant (fractal or self-similar) multioscillator.

Lloyd D, Murray DB, Aon MA, Cortassa S, Roussel MR, Beckmann M, Poole RK.

J Biomed Opt. 2018 Dec;24(5):1-17. doi: 10.1117/1.JBO.24.5.051404.


A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.

Rodriguez-Blanco J, Li B, Long J, Shen C, Yang F, Orton D, Collins S, Kasahara N, Ayad NG, McCrea HJ, Roussel MF, Weiss WA, Capobianco AJ, Robbins DJ.

Clin Cancer Res. 2019 Feb 15;25(4):1379-1388. doi: 10.1158/1078-0432.CCR-18-1319. Epub 2018 Nov 28.


Multicenter validation of the flow measurement of classical monocyte fraction for chronic myelomonocytic leukemia diagnosis.

Tarfi S, Harrivel V, Dumezy F, Guy J, Roussel M, Mimoun A, Fenaux P, Chapuis N, Solary E, Selimoglu-Buet D, Wagner-Ballon O; Groupe Francophone des Myélodysplasies (GFM).

Blood Cancer J. 2018 Nov 14;8(11):114. doi: 10.1038/s41408-018-0146-8.


Dysexecutive disorders and their diagnosis: A position paper.

Godefroy O, Martinaud O, Narme P, Joseph PA, Mosca C, Lhommée E, Meulemans T, Czernecki V, Bertola C, Labauge P, Verny M, Bellmann A, Azouvi P, Bindschaedler C, Bretault E, Boutoleau-Bretonniere C, Robert P, Lenoir H, Krier M, Roussel M; GREFEX study group.

Cortex. 2018 Dec;109:322-335. doi: 10.1016/j.cortex.2018.09.026. Epub 2018 Oct 17. Review.


Reference Values for WBC Differential by Hematoflow Analysis.

Magierowicz M, Lechevalier N, Freynet N, Pastoret C, Badaoui B, Ly-Sunnaram B, Fest T, Lacombe F, Wagner-Ballon O, Roussel M.

Am J Clin Pathol. 2019 Feb 4;151(3):324-327. doi: 10.1093/ajcp/aqy147.


Preclinical Modeling of Image-Guided Craniospinal Irradiation for Very-High-Risk Medulloblastoma.

Smith SMC, Bianski BM, Orr BA, Harknett G, Onar-Thomas A, Gilbertson RJ, Merchant TE, Roussel MF, Tinkle CL.

Int J Radiat Oncol Biol Phys. 2019 Mar 1;103(3):728-737. doi: 10.1016/j.ijrobp.2018.10.015. Epub 2018 Oct 23.


Myeloma MRD by deep sequencing from circulating tumor DNA does not correlate with results obtained in the bone marrow.

Mazzotti C, Buisson L, Maheo S, Perrot A, Chretien ML, Leleu X, Hulin C, Manier S, Hébraud B, Roussel M, Do Souto L, Attal M, Avet-Loiseau H, Corre J.

Blood Adv. 2018 Nov 13;2(21):2811-2813. doi: 10.1182/bloodadvances.2018025197. No abstract available.


Neuroimaging Determinants of Poststroke Cognitive Performance.

Puy L, Barbay M, Roussel M, Canaple S, Lamy C, Arnoux A, Leclercq C, Mas JL, Tasseel-Ponche S, Constans JM, Godefroy O; GRECogVASC Study Group.

Stroke. 2018 Nov;49(11):2666-2673. doi: 10.1161/STROKEAHA.118.021981.


Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma.

Desmots F, Roussel M, Pangault C, Llamas-Gutierrez F, Pastoret C, Guiheneuf E, Le Priol J, Camara-Clayette V, Caron G, Henry C, Belaud-Rotureau MA, Godmer P, Lamy T, Jardin F, Tarte K, Ribrag V, Fest T.

Clin Cancer Res. 2019 Jan 15;25(2):735-746. doi: 10.1158/1078-0432.CCR-18-1153. Epub 2018 Oct 22.


Who should undergo a comprehensive cognitive assessment after a stroke? A cognitive risk score.

Godefroy O, Yaïche H, Taillia H, Bompaire F, Nédélec-Ciceri C, Bonnin C, Varvat J, Vincent-Grangette F, Diouf M, Mas JL, Canaple S, Lamy C, Arnoux A, Leclercq C, Tasseel-Ponche S, Roussel M, Barbay M; GRECogVASC Study Group.

Neurology. 2018 Nov 20;91(21):e1979-e1987. doi: 10.1212/WNL.0000000000006544. Epub 2018 Oct 17.


A mathematical model of the biochemical network underlying left-right asymmetry establishment in mammals.

Roussel CJ, Roussel MR.

Biosystems. 2018 Nov;173:281-297. doi: 10.1016/j.biosystems.2018.10.003. Epub 2018 Oct 4.


Pomalidomide, cyclophosphamide, and dexamethasone for relapsed multiple myeloma.

Garderet L, Kuhnowski F, Berge B, Roussel M, Escoffre-Barbe M, Lafon I, Facon T, Leleu X, Karlin L, Perrot A, Moreau P, Marit G, Stoppa AM, Royer B, Chaleteix C, Tiab M, Araujo C, Lenain P, Macro M, Voog E, Benboubker L, Allangba O, Jourdan E, Orsini-Piocelle F, Brechignac S, Eveillard JR, Belhadj K, Wetterwald M, Pegourie B, Jaccard A, Eisenmann JC, Glaisner S, Mohty M, Hulin C, Loiseau HA, Mathiot C, Attal M.

Blood. 2018 Dec 13;132(24):2555-2563. doi: 10.1182/blood-2018-07-863829. Epub 2018 Oct 3.


Tacrolimus diffusion across the peripheral mononuclear blood cell membrane: impact of drug transporters.

Tron C, Allard M, Petitcollin A, Ferrand-Sorre MJ, Verdier MC, Querzerho-Raguideau J, Blanchet B, Le Priol J, Roussel M, Deugnier Y, Bellissant E, Lemaitre F.

Fundam Clin Pharmacol. 2019 Feb;33(1):113-121. doi: 10.1111/fcp.12412. Epub 2018 Oct 14.


Cognitive Impairments and Dysexecutive Behavioral Disorders in Chronic Kidney Disease.

Puy L, Bugnicourt JM, Liabeuf S, Desjardins L, Roussel M, Diouf M, Chillon JM, Choukroun G, Massy ZA, Godefroy O.

J Neuropsychiatry Clin Neurosci. 2018 Fall;30(4):310-317. doi: 10.1176/appi.neuropsych.18030047. Epub 2018 Jul 26.


Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.

Pajtler KW, Wen J, Sill M, Lin T, Orisme W, Tang B, Hübner JM, Ramaswamy V, Jia S, Dalton JD, Haupfear K, Rogers HA, Punchihewa C, Lee R, Easton J, Wu G, Ritzmann TA, Chapman R, Chavez L, Boop FA, Klimo P, Sabin ND, Ogg R, Mack SC, Freibaum BD, Kim HJ, Witt H, Jones DTW, Vo B, Gajjar A, Pounds S, Onar-Thomas A, Roussel MF, Zhang J, Taylor JP, Merchant TE, Grundy R, Tatevossian RG, Taylor MD, Pfister SM, Korshunov A, Kool M, Ellison DW.

Acta Neuropathol. 2018 Aug;136(2):211-226. doi: 10.1007/s00401-018-1877-0. Epub 2018 Jun 16.


Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF.

Sci Rep. 2018 Jun 7;8(1):8733. doi: 10.1038/s41598-018-24956-1.


A predictive model for risk of early grade ≥ 3 infection in patients with multiple myeloma not eligible for transplant: analysis of the FIRST trial.

Dumontet C, Hulin C, Dimopoulos MA, Belch A, Dispenzieri A, Ludwig H, Rodon P, Van Droogenbroeck J, Qiu L, Cavo M, Van de Velde A, Lahuerta JJ, Allangba O, Lee JH, Boyle E, Perrot A, Moreau P, Manier S, Attal M, Roussel M, Mohty M, Mary JY, Civet A, Costa B, Tinel A, Gaston-Mathé Y, Facon T.

Leukemia. 2018 Jun;32(6):1404-1413. doi: 10.1038/s41375-018-0133-x. Epub 2018 Apr 26.


The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma.

Ganguly D, Fan M, Yang CH, Zbytek B, Finkelstein D, Roussel MF, Pfeffer LM.

Oncotarget. 2018 Apr 24;9(31):22095-22112. doi: 10.18632/oncotarget.25188. eCollection 2018 Apr 24.


Multicentric Standardized Flow Cytometry Routine Assessment of Patients With Sepsis to Predict Clinical Worsening.

Daix T, Guerin E, Tavernier E, Mercier E, Gissot V, Hérault O, Mira JP, Dumas F, Chapuis N, Guitton C, Béné MC, Quenot JP, Tissier C, Guy J, Piton G, Roggy A, Muller G, Legac É, de Prost N, Khellaf M, Wagner-Ballon O, Coudroy R, Dindinaud E, Uhel F, Roussel M, Lafon T, Jeannet R, Vargas F, Fleureau C, Roux M, Allou K, Vignon P, Feuillard J, François B; Septiflux Trial Group.

Chest. 2018 Sep;154(3):617-627. doi: 10.1016/j.chest.2018.03.058. Epub 2018 Apr 26.


Development and validation of a sensitive LC MS/MS method for the measurement of the checkpoint kinase 1 inhibitor prexasertib and its application in a cerebral microdialysis study.

Zhong B, Maharaj A, Davis A, Roussel MF, Stewart CF.

J Pharm Biomed Anal. 2018 Jul 15;156:97-103. doi: 10.1016/j.jpba.2018.04.018. Epub 2018 Apr 17.


Differentiating between Alzheimer's Disease and Vascular Cognitive Impairment: Is the "Memory Versus Executive Function" Contrast Still Relevant?

Andriuta D, Roussel M, Barbay M, Despretz-Wannepain S, Godefroy O; Godefroy and GRECogVASC study group.

J Alzheimers Dis. 2018;63(2):625-633. doi: 10.3233/JAD-171097.


Prevalence of Poststroke Neurocognitive Disorders Using National Institute of Neurological Disorders and Stroke-Canadian Stroke Network, VASCOG Criteria (Vascular Behavioral and Cognitive Disorders), and Optimized Criteria of Cognitive Deficit.

Barbay M, Taillia H, Nédélec-Ciceri C, Bompaire F, Bonnin C, Varvat J, Grangette F, Diouf M, Wiener E, Mas JL, Roussel M, Godefroy O; GRECOG-VASC Study Group.

Stroke. 2018 May;49(5):1141-1147. doi: 10.1161/STROKEAHA.117.018889. Epub 2018 Apr 11.


Linking influenza epidemic onsets to covariates at different scales using a dynamical model.

Roussel M, Pontier D, Cohen JM, Lina B, Fouchet D.

PeerJ. 2018 Mar 8;6:e4440. doi: 10.7717/peerj.4440. eCollection 2018.


Distinct Contributions of Mesencephalic Locomotor Region Nuclei to Locomotor Control in the Freely Behaving Mouse.

Josset N, Roussel M, Lemieux M, Lafrance-Zoubga D, Rastqar A, Bretzner F.

Curr Biol. 2018 Mar 19;28(6):884-901.e3. doi: 10.1016/j.cub.2018.02.007. Epub 2018 Mar 8.


CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss.

Teitz T, Fang J, Goktug AN, Bonga JD, Diao S, Hazlitt RA, Iconaru L, Morfouace M, Currier D, Zhou Y, Umans RA, Taylor MR, Cheng C, Min J, Freeman B, Peng J, Roussel MF, Kriwacki R, Guy RK, Chen T, Zuo J.

J Exp Med. 2018 Apr 2;215(4):1187-1203. doi: 10.1084/jem.20172246. Epub 2018 Mar 7.


IGHV segment utilization in immunoglobulin gene rearrangement differentiates patients with anti-myelin-associated glycoprotein neuropathy from others immunoglobulin M-gammopathies.

Allain JS, Thonier F, Pihan M, Boulland ML, de Guibert S, Launay V, Doncker AV, Ganard M, Aliouat A, Pangault C, Houot R, De Tayrac M, Lamy T, Roussel M, Fest T, Decaux O, Pastoret C.

Haematologica. 2018 May;103(5):e207-e210. doi: 10.3324/haematol.2017.177444. Epub 2018 Jan 25. No abstract available.


A new genetically engineered mouse model of choroid plexus carcinoma.

El Nagar S, Zindy F, Moens C, Martin L, Plassard D, Roussel MF, Lamonerie T, Billon N.

Biochem Biophys Res Commun. 2018 Feb 5;496(2):568-574. doi: 10.1016/j.bbrc.2017.11.192. Epub 2018 Jan 12.


Salvage therapy post pomalidomide-based regimen in relapsed/refractory myeloma.

Fouquet G, Karlin L, Macro M, Caillot D, Roussel M, Arnulf B, Pegourie B, Petillon MO, Mathiot C, Hulin C, Kolb B, Stoppa AM, Brechiniac S, Rodon P, Dib M, Tiab M, Richez V, Araujo C, Wetterwald M, Garderet L, Royer B, Perrot A, Benboubker L, Decaux O, Escoffre-Barbe M, Fermand JP, Moreau P, Avet-Loiseau H, Attal M, Facon T, Leleu X.

Ann Hematol. 2018 May;97(5):831-837. doi: 10.1007/s00277-018-3236-6. Epub 2018 Jan 12.


Establishing a Preclinical Multidisciplinary Board for Brain Tumors.

Nimmervoll BV, Boulos N, Bianski B, Dapper J, DeCuypere M, Shelat A, Terranova S, Terhune HE, Gajjar A, Patel YT, Freeman BB, Onar-Thomas A, Stewart CF, Roussel MF, Guy RK, Merchant TE, Calabrese C, Wright KD, Gilbertson RJ.

Clin Cancer Res. 2018 Apr 1;24(7):1654-1666. doi: 10.1158/1078-0432.CCR-17-2168. Epub 2018 Jan 4.

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