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Identification of MAGUK scaffold proteins as intracellular binding partners of synaptic adhesion protein Slitrk2.

Loomis C, Stephens A, Janicot R, Baqai U, Drebushenko L, Round J.

Mol Cell Neurosci. 2020 Jan 8;103:103465. doi: 10.1016/j.mcn.2019.103465. [Epub ahead of print]


Nurse-led medicines' monitoring in care homes, implementing the Adverse Drug Reaction (ADRe) Profile improvement initiative for mental health medicines: An observational and interview study.

Jordan S, Banner T, Gabe-Walters M, Mikhail JM, Panes G, Round J, Snelgrove S, Storey M, Hughes D; Medicines’ Management Group, Swansea University.

PLoS One. 2019 Sep 11;14(9):e0220885. doi: 10.1371/journal.pone.0220885. eCollection 2019.


Hard choices: Reflections from the tomb of the unknown patient.

McCabe C, Round J.

Healthc Manage Forum. 2019 Nov;32(6):288-292. doi: 10.1177/0840470419871319. Epub 2019 Sep 10.


Continuing the conversation - Free Online Open Access Meducation (FOAM).

Barton J, Round J.

Med Teach. 2019 Sep 6:1. doi: 10.1080/0142159X.2019.1657566. [Epub ahead of print] No abstract available.


Protocol for a feasibility randomised trial of low-intensity interventions for antenatal depression: ADAGIO trial comparing interpersonal counselling with cognitive behavioural therapy.

Ingram J, Johnson D, Johnson S, O'Mahen HA, Kessler D, Taylor H, Law R, Round J, Ford J, Hopley R, Glynn J, Culpin I, Evans J.

BMJ Open. 2019 Aug 18;9(8):e032649. doi: 10.1136/bmjopen-2019-032649.


T cell-mediated regulation of the microbiota protects against obesity.

Petersen C, Bell R, Klag KA, Lee SH, Soto R, Ghazaryan A, Buhrke K, Ekiz HA, Ost KS, Boudina S, O'Connell RM, Cox JE, Villanueva CJ, Stephens WZ, Round JL.

Science. 2019 Jul 26;365(6451). pii: eaat9351. doi: 10.1126/science.aat9351.


The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling.

Brown DG, Soto R, Yandamuri S, Stone C, Dickey L, Gomes-Neto JC, Pastuzyn ED, Bell R, Petersen C, Buhrke K, Fujinami RS, O'Connell RM, Stephens WZ, Shepherd JD, Lane TE, Round JL.

Elife. 2019 Jul 16;8. pii: e47117. doi: 10.7554/eLife.47117.


Clinical and cost-effectiveness of the Ross procedure versus conventional aortic valve replacement in young adults.

Thom H, Visan AC, Keeney E, Dorobantu DM, Fudulu D, T A Sharabiani M, Round J, Stoica SC.

Open Heart. 2019 May 22;6(1):e001047. doi: 10.1136/openhrt-2019-001047. eCollection 2019. Erratum in: Open Heart. 2019 Jun 18;6(1):e001047corr1.


Does MHC heterozygosity influence microbiota form and function?

Khan MAW, Stephens WZ, Mohammed AD, Round JL, Kubinak JL.

PLoS One. 2019 May 16;14(5):e0215946. doi: 10.1371/journal.pone.0215946. eCollection 2019.


Virtual patients designed for training against medical error: Exploring the impact of decision-making on learner motivation.

Woodham LA, Round J, Stenfors T, Bujacz A, Karlgren K, Jivram T, Riklefs V, Poulton E, Poulton T.

PLoS One. 2019 Apr 23;14(4):e0215597. doi: 10.1371/journal.pone.0215597. eCollection 2019.


Expansion of the known distribution of the coastal tailed frog, Ascaphus truei, in British Columbia, Canada, using robust eDNA detection methods.

Hobbs J, Round JM, Allison MJ, Helbing CC.

PLoS One. 2019 Mar 14;14(3):e0213849. doi: 10.1371/journal.pone.0213849. eCollection 2019.


Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease.

Runtsch MC, Nelson MC, Lee SH, Voth W, Alexander M, Hu R, Wallace J, Petersen C, Panic V, Villanueva CJ, Evason KJ, Bauer KM, Mosbruger T, Boudina S, Bronner M, Round JL, Drummond MJ, O'Connell RM.

PLoS Genet. 2019 Feb 15;15(2):e1007970. doi: 10.1371/journal.pgen.1007970. eCollection 2019 Feb.


Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.

Gogokhia L, Buhrke K, Bell R, Hoffman B, Brown DG, Hanke-Gogokhia C, Ajami NJ, Wong MC, Ghazaryan A, Valentine JF, Porter N, Martens E, O'Connell R, Jacob V, Scherl E, Crawford C, Stephens WZ, Casjens SR, Longman RS, Round JL.

Cell Host Microbe. 2019 Feb 13;25(2):285-299.e8. doi: 10.1016/j.chom.2019.01.008.


MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers.

Ekiz HA, Huffaker TB, Grossmann AH, Stephens WZ, Williams MA, Round JL, O'Connell RM.

JCI Insight. 2019 Mar 21;4(6). pii: 126543. doi: 10.1172/jci.insight.126543. eCollection 2019 Mar 21.


Fiber Puts Lactobacillus to SLEep.

Chiaro TR, Round JL.

Cell Host Microbe. 2019 Jan 9;25(1):3-5. doi: 10.1016/j.chom.2018.12.012.


Evaluation of Gene Bioindicators in the Liver and Caudal Fin of Juvenile Pacific Coho Salmon in Response to Low Sulfur Marine Diesel Seawater-Accommodated Fraction Exposure.

Imbery JJ, Buday C, Miliano RC, Shang D, Round JM, Kwok H, Van Aggelen G, Helbing CC.

Environ Sci Technol. 2019 Feb 5;53(3):1627-1638. doi: 10.1021/acs.est.8b05429. Epub 2019 Jan 18.


Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT.

Kessler D, Burns A, Tallon D, Lewis G, MacNeill S, Round J, Hollingworth W, Chew-Graham C, Anderson I, Campbell J, Dickens C, Macleod U, Gilbody S, Davies S, Peters TJ, Wiles N.

Health Technol Assess. 2018 Nov;22(63):1-136. doi: 10.3310/hta22630.


Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).

Kessler DS, MacNeill SJ, Tallon D, Lewis G, Peters TJ, Hollingworth W, Round J, Burns A, Chew-Graham CA, Anderson IM, Shepherd T, Campbell J, Dickens CM, Carter M, Jenkinson C, Macleod U, Gibson H, Davies S, Wiles NJ.

BMJ. 2018 Oct 31;363:k4218. doi: 10.1136/bmj.k4218. Erratum in: BMJ. 2018 Nov 15;363:k4691.


Nurse-led medicines' monitoring in care homes study protocol: a process evaluation of the impact and sustainability of the adverse drug reaction (ADRe) profile for mental health medicines.

Jordan S, Banner T, Gabe-Walters M, Mikhail JM, Round J, Snelgrove S, Storey M, Wilson D, Hughes D; Medicines Management Group.

BMJ Open. 2018 Sep 28;8(9):e023377. doi: 10.1136/bmjopen-2018-023377.


Gut microbiota: a new way to take your vitamins.

Gomes-Neto JC, Round JL.

Nat Rev Gastroenterol Hepatol. 2018 Sep;15(9):521-522. doi: 10.1038/s41575-018-0044-3. No abstract available.


Communication Between the Microbiota and Mammalian Immunity.

Ost KS, Round JL.

Annu Rev Microbiol. 2018 Sep 8;72:399-422. doi: 10.1146/annurev-micro-090817-062307. Epub 2018 Jun 21. Review.


Remote physiological monitoring in an austere environment: a future for battlefield care provision?

Smyth MJ, Round JA, Mellor AJ.

J R Army Med Corps. 2018 Nov;164(6):410-413. doi: 10.1136/jramc-2017-000905. Epub 2018 May 14.


Commensal regulation of T cell survival through Erdr1.

Weis AM, Soto R, Round JL.

Gut Microbes. 2018;9(5):458-464. doi: 10.1080/19490976.2018.1441662. Epub 2018 Apr 11. Review.


Once Bitten Twice Shy: Thinking Carefully Before Adopting the EQ-5D-5L.

Round J.

Pharmacoeconomics. 2018 Jun;36(6):641-643. doi: 10.1007/s40273-018-0636-3. No abstract available.


Statistical Alchemy: Conceptual Validity and Mapping to Generate Health State Utility Values.

Round J, Hawton A.

Pharmacoecon Open. 2017 Dec;1(4):233-239. doi: 10.1007/s41669-017-0027-2.


Causal effects of the microbiota on immune-mediated diseases.

Round JL, Palm NW.

Sci Immunol. 2018 Feb 9;3(20). pii: eaao1603. doi: 10.1126/sciimmunol.aao1603. Review.


Variations in diet cause alterations in microbiota and metabolites that follow changes in disease severity in a multiple sclerosis model.

Libbey JE, Sanchez JM, Doty DJ, Sim JT, Cusick MF, Cox JE, Fischer KF, Round JL, Fujinami RS.

Benef Microbes. 2018 Apr 25;9(3):495-513. doi: 10.3920/BM2017.0116. Epub 2018 Jan 30.


IL-10 Deficiency Reveals a Role for TLR2-Dependent Bystander Activation of T Cells in Lyme Arthritis.

Whiteside SK, Snook JP, Ma Y, Sonderegger FL, Fisher C, Petersen C, Zachary JF, Round JL, Williams MA, Weis JJ.

J Immunol. 2018 Feb 15;200(4):1457-1470. doi: 10.4049/jimmunol.1701248. Epub 2018 Jan 12.


Global lessons: developing military trauma care and lessons for civilian practice.

Woolley T, Round JA, Ingram M.

Br J Anaesth. 2017 Dec 1;119(suppl_1):i135-i142. doi: 10.1093/bja/aex382. Review.


Cirrhosis with ascites in the last year of life: a nationwide analysis of factors shaping costs, health-care use, and place of death in England.

Hudson B, Round J, Georgeson B, Pring A, Forbes K, McCune CA, Verne J.

Lancet Gastroenterol Hepatol. 2018 Feb;3(2):95-103. doi: 10.1016/S2468-1253(17)30362-X. Epub 2017 Nov 15. Erratum in: Lancet Gastroenterol Hepatol. 2019 Feb;4(2):e1.


The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA.

Hammond SA, Warren RL, Vandervalk BP, Kucuk E, Khan H, Gibb EA, Pandoh P, Kirk H, Zhao Y, Jones M, Mungall AJ, Coope R, Pleasance S, Moore RA, Holt RA, Round JM, Ohora S, Walle BV, Veldhoen N, Helbing CC, Birol I.

Nat Commun. 2017 Nov 10;8(1):1433. doi: 10.1038/s41467-017-01316-7.


Friends in Low Places: Intestinal Commensals Limit Colitis through Molecular Mimicry.

Brown DG, Round JL.

Cell. 2017 Oct 19;171(3):503-505. doi: 10.1016/j.cell.2017.09.053.


Lancet Commission: Stem cells and regenerative medicine.

Cossu G, Birchall M, Brown T, De Coppi P, Culme-Seymour E, Gibbon S, Hitchcock J, Mason C, Montgomery J, Morris S, Muntoni F, Napier D, Owji N, Prasad A, Round J, Saprai P, Stilgoe J, Thrasher A, Wilson J.

Lancet. 2018 Mar 3;391(10123):883-910. doi: 10.1016/S0140-6736(17)31366-1. Epub 2017 Oct 4. Review. No abstract available. Erratum in: Lancet. 2018 Mar 10;391(10124):e8.


Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli.

Alexander M, Ramstead AG, Bauer KM, Lee SH, Runtsch MC, Wallace J, Huffaker TB, Larsen DK, Tolmachova T, Seabra MC, Round JL, Ward DM, O'Connell RM.

J Immunol. 2017 Nov 15;199(10):3559-3570. doi: 10.4049/jimmunol.1700904. Epub 2017 Oct 4.


Identifying frailty in primary care.

Hamilton W, Round J.

BMJ. 2017 Sep 27;358:j4478. doi: 10.1136/bmj.j4478. No abstract available.


Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.

Huffaker TB, Lee SH, Tang WW, Wallace JA, Alexander M, Runtsch MC, Larsen DK, Thompson J, Ramstead AG, Voth WP, Hu R, Round JL, Williams MA, O'Connell RM.

J Biol Chem. 2017 Nov 10;292(45):18530-18541. doi: 10.1074/jbc.M117.808121. Epub 2017 Sep 14.


A Fatty Acyl Coenzyme A Reductase Promotes Wax Ester Accumulation in Rhodococcus jostii RHA1.

Round J, Roccor R, Li SN, Eltis LD.

Appl Environ Microbiol. 2017 Sep 29;83(20). pii: e00902-17. doi: 10.1128/AEM.00902-17. Print 2017 Oct 15.


Exploring the relationship between frequent internet use and health and social care resource use in a community-based cohort of older adults: an observational study in primary care.

Clarke CS, Round J, Morris S, Kharicha K, Ford J, Manthorpe J, Iliffe S, Goodman C, Walters K.

BMJ Open. 2017 Jul 21;7(7):e015839. doi: 10.1136/bmjopen-2017-015839.


A Few Good Commensals: Gut Microbes Use IFN-γ to Fight Salmonella.

Ost KS, Round JL.

Immunity. 2017 Jun 20;46(6):977-979. doi: 10.1016/j.immuni.2017.06.010.


Incorporating equity in economic evaluations: a multi-attribute equity state approach.

Round J, Paulden M.

Eur J Health Econ. 2018 May;19(4):489-498. doi: 10.1007/s10198-017-0897-3. Epub 2017 Jun 1.


Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor.

Soto R, Petersen C, Novis CL, Kubinak JL, Bell R, Stephens WZ, Lane TE, Fujinami RS, Bosque A, O'Connell RM, Round JL.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5497-5502. doi: 10.1073/pnas.1619336114. Epub 2017 May 9.


miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.

Wallace JA, Kagele DA, Eiring AM, Kim CN, Hu R, Runtsch MC, Alexander M, Huffaker TB, Lee SH, Patel AB, Mosbruger TL, Voth WP, Rao DS, Miles RR, Round JL, Deininger MW, O'Connell RM.

Blood. 2017 Jun 8;129(23):3074-3086. doi: 10.1182/blood-2016-09-740209. Epub 2017 Apr 21.


Promoting independence, health and well-being for older people: a feasibility study of computer-aided health and social risk appraisal system in primary care.

Walters K, Kharicha K, Goodman C, Handley M, Manthorpe J, Cattan M, Morris S, Clarke CS, Round J, Iliffe S.

BMC Fam Pract. 2017 Mar 24;18(1):47. doi: 10.1186/s12875-017-0620-6.


Addressing the double-burden of diabetes and tuberculosis: lessons from Kyrgyzstan.

Skordis-Worrall J, Round J, Arnold M, Abdraimova A, Akkazieva B, Beran D.

Global Health. 2017 Mar 15;13(1):16. doi: 10.1186/s12992-017-0239-3.


A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice.

Chiaro TR, Soto R, Zac Stephens W, Kubinak JL, Petersen C, Gogokhia L, Bell R, Delgado JC, Cox J, Voth W, Brown J, Stillman DJ, O'Connell RM, Tebo AE, Round JL.

Sci Transl Med. 2017 Mar 8;9(380). pii: eaaf9044. doi: 10.1126/scitranslmed.aaf9044. Erratum in: Sci Transl Med. 2017 May 3;9(388):.


Enhanced delignification of steam-pretreated poplar by a bacterial laccase.

Singh R, Hu J, Regner MR, Round JW, Ralph J, Saddler JN, Eltis LD.

Sci Rep. 2017 Feb 7;7:42121. doi: 10.1038/srep42121.


Military Anaesthesia in contingencies: what skill sets are required and how will we prepare our trainees?

Mercer SJ, Jones CL, Round J, Parkhouse D.

J R Army Med Corps. 2017 Aug;163(4):226-232. doi: 10.1136/jramc-2016-000722. Epub 2017 Feb 3.


Dual colorimetric and fluorogenic probes for visualizing tyrosine phosphatase activity.

Biswas S, McCullough BS, Ma ES, LaJoie D, Russell CW, Garrett Brown D, Round JL, Ullman KS, Mulvey MA, Barrios AM.

Chem Commun (Camb). 2017 Feb 14;53(14):2233-2236. doi: 10.1039/c6cc09204g.


Vocal Cord Palsy in Children With Cancer: A 10-Year Analysis of UK Pediatric Intensive Care Admissions.

Capsomidis A, Hall A, Daya H, Round J, Lancaster D, Bate J.

J Pediatr Hematol Oncol. 2017 May;39(4):293-295. doi: 10.1097/MPH.0000000000000772.


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