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Items: 24


A highly standardized and characterized human platelet lysate for efficient and reproducible expansion of human bone marrow mesenchymal stromal cells.

Viau S, Lagrange A, Chabrand L, Lorant J, Charrier M, Rouger K, Alvarez I, Eap S, Delorme B.

Cytotherapy. 2019 May 24. pii: S1465-3249(19)30457-8. doi: 10.1016/j.jcyt.2019.04.053. [Epub ahead of print]


Satellite cells fail to contribute to muscle repair but are functional in Pompe disease (glycogenosis type II).

Lagalice L, Pichon J, Gougeon E, Soussi S, Deniaud J, Ledevin M, Maurier V, Leroux I, Durand S, Ciron C, Franzoso F, Dubreil L, Larcher T, Rouger K, Colle MA.

Acta Neuropathol Commun. 2018 Oct 31;6(1):116. doi: 10.1186/s40478-018-0609-y.


Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits.

Lorant J, Larcher T, Jaulin N, Hedan B, Lardenois A, Leroux I, Dubreil L, Ledevin M, Goubin H, Moullec S, Deschamps JY, Thorin C, André C, Adjali O, Rouger K.

Cell Transplant. 2018 Jul;27(7):1096-1110. doi: 10.1177/0963689718776306. Epub 2018 Jun 5.


Human serum and platelet lysate are appropriate xeno-free alternatives for clinical-grade production of human MuStem cell batches.

Saury C, Lardenois A, Schleder C, Leroux I, Lieubeau B, David L, Charrier M, Guével L, Viau S, Delorme B, Rouger K.

Stem Cell Res Ther. 2018 May 2;9(1):128. doi: 10.1186/s13287-018-0852-y.


Skeletal Muscle Regenerative Potential of Human MuStem Cells following Transplantation into Injured Mice Muscle.

Lorant J, Saury C, Schleder C, Robriquet F, Lieubeau B, Négroni E, Leroux I, Chabrand L, Viau S, Babarit C, Ledevin M, Dubreil L, Hamel A, Magot A, Thorin C, Guevel L, Delorme B, Péréon Y, Butler-Browne G, Mouly V, Rouger K.

Mol Ther. 2018 Feb 7;26(2):618-633. doi: 10.1016/j.ymthe.2017.10.013. Epub 2017 Oct 20.


Pathogen reduction through additive-free short-wave UV light irradiation retains the optimal efficacy of human platelet lysate for the expansion of human bone marrow mesenchymal stem cells.

Viau S, Chabrand L, Eap S, Lorant J, Rouger K, Goudaliez F, Sumian C, Delorme B.

PLoS One. 2017 Aug 1;12(8):e0181406. doi: 10.1371/journal.pone.0181406. eCollection 2017.


Multi-harmonic Imaging in the Second Near-Infrared Window of Nanoparticle-Labeled Stem Cells as a Monitoring Tool in Tissue Depth.

Dubreil L, Leroux I, Ledevin M, Schleder C, Lagalice L, Lovo C, Fleurisson R, Passemard S, Kilin V, Gerber-Lemaire S, Colle MA, Bonacina L, Rouger K.

ACS Nano. 2017 Jul 25;11(7):6672-6681. doi: 10.1021/acsnano.7b00773. Epub 2017 Jun 27.


Gait characterization in golden retriever muscular dystrophy dogs using linear discriminant analysis.

Fraysse B, Barthélémy I, Qannari EM, Rouger K, Thorin C, Blot S, Le Guiner C, Chérel Y, Hogrel JY.

BMC Musculoskelet Disord. 2017 Apr 12;18(1):153. doi: 10.1186/s12891-017-1494-4.


Quantitative proteome profiling of dystrophic dog skeletal muscle reveals a stabilized muscular architecture and protection against oxidative stress after systemic delivery of MuStem cells.

Lardenois A, Jagot S, Lagarrigue M, Guével B, Ledevin M, Larcher T, Dubreil L, Pineau C, Rouger K, Guével L.

Proteomics. 2016 Jul;16(14):2028-42. doi: 10.1002/pmic.201600002.


Identification in GRMD dog muscle of critical miRNAs involved in pathophysiology and effects associated with MuStem cell transplantation.

Robriquet F, Babarit C, Larcher T, Dubreil L, Ledevin M, Goubin H, Rouger K, Guével L.

BMC Musculoskelet Disord. 2016 May 11;17:209. doi: 10.1186/s12891-016-1060-5.


Differential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell Transplantation.

Robriquet F, Lardenois A, Babarit C, Larcher T, Dubreil L, Leroux I, Zuber C, Ledevin M, Deschamps JY, Fromes Y, Cherel Y, Guevel L, Rouger K.

PLoS One. 2015 May 8;10(5):e0123336. doi: 10.1371/journal.pone.0123336. eCollection 2015.


Systemic delivery of allogenic muscle stem cells induces long-term muscle repair and clinical efficacy in duchenne muscular dystrophy dogs.

Rouger K, Larcher T, Dubreil L, Deschamps JY, Le Guiner C, Jouvion G, Delorme B, Lieubeau B, Carlus M, Fornasari B, Theret M, Orlando P, Ledevin M, Zuber C, Leroux I, Deleau S, Guigand L, Testault I, Le Rumeur E, Fiszman M, Chérel Y.

Am J Pathol. 2011 Nov;179(5):2501-18. doi: 10.1016/j.ajpath.2011.07.022. Epub 2011 Sep 13.


Fetal muscle contains different CD34+ cell subsets that distinctly differentiate into adipogenic, angiogenic and myogenic lineages.

Dupas T, Rouaud T, Rouger K, Lieubeau B, Cario-Toumaniantz C, Fontaine-Pérus J, Gardahaut MF, Auda-Boucher G.

Stem Cell Res. 2011 Nov;7(3):230-43. doi: 10.1016/j.scr.2011.06.004. Epub 2011 Jul 2.


Quantitative proteomic analysis of dystrophic dog muscle.

Guevel L, Lavoie JR, Perez-Iratxeta C, Rouger K, Dubreil L, Feron M, Talon S, Brand M, Megeney LA.

J Proteome Res. 2011 May 6;10(5):2465-78. doi: 10.1021/pr2001385. Epub 2011 Mar 29.


Aldehyde dehydrogenase activity promotes survival of human muscle precursor cells.

Jean E, Laoudj-Chenivesse D, Notarnicola C, Rouger K, Serratrice N, Bonnieu A, Gay S, Bacou F, Duret C, Carnac G.

J Cell Mol Med. 2011 Jan;15(1):119-33. doi: 10.1111/j.1582-4934.2009.00942.x.


PTEN contributes to profound PI3K/Akt signaling pathway deregulation in dystrophin-deficient dog muscle.

Feron M, Guevel L, Rouger K, Dubreil L, Arnaud MC, Ledevin M, Megeney LA, Cherel Y, Sakanyan V.

Am J Pathol. 2009 Apr;174(4):1459-70. doi: 10.2353/ajpath.2009.080460. Epub 2009 Mar 5.


Progenitor cell isolation from muscle-derived cells based on adhesion properties.

Rouger K, Fornasari B, Armengol V, Jouvion G, Leroux I, Dubreil L, Feron M, Guevel L, Cherel Y.

J Histochem Cytochem. 2007 Jun;55(6):607-18. Epub 2007 Feb 20.


Functional properties of muscle-derived cells related to morphological characteristics.

Jouvion G, Rouger K, Fornasari B, Bougras G, Leroux I, Segalen J, Cherel Y.

Histochem Cell Biol. 2006 Nov;126(5):603-16. Epub 2006 Jun 10.


Muscle satellite cell heterogeneity: in vitro and in vivo evidences for populations that fuse differently.

Rouger K, Brault M, Daval N, Leroux I, Guigand L, Lesoeur J, Fernandez B, Cherel Y.

Cell Tissue Res. 2004 Sep;317(3):319-26. Epub 2004 Aug 3.


S-protein is expressed in necrotic fibers in Duchenne muscular dystrophy and polymyositis.

Louboutin JP, Navenot JM, Rouger K, Blanchard D.

Muscle Nerve. 2003 May;27(5):575-81.


Global/temporal gene expression in diaphragm and hindlimb muscles of dystrophin-deficient (mdx) mice.

Rouger K, Le Cunff M, Steenman M, Potier MC, Gibelin N, Dechesne CA, Leger JJ.

Am J Physiol Cell Physiol. 2002 Sep;283(3):C773-84.


iNOS expression in dystrophinopathies can be reduced by somatic gene transfer of dystrophin or utrophin.

Louboutin JP, Rouger K, Tinsley JM, Halldorson J, Wilson JM.

Mol Med. 2001 May;7(5):355-64.


X-linked vacuolated myopathy : TNF-alpha and IFN-gamma expression in muscle fibers with MHC class I on sarcolemma.

Rouger K, Louboutin JP, Villanova M, Cherel Y, Fardeau M.

Am J Pathol. 2001 Feb;158(2):355-9.


X-linked vacuolated myopathy: membrane attack complex deposition on the surface membrane of injured muscle fibers is not accompanied by S-protein.

Louboutin JP, Navenot JM, Villanova M, Rouger K, Merlini L, Fardeau M.

Muscle Nerve. 1998 Jul;21(7):932-5.


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