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Personalised mechanical ventilation tailored to lung morphology versus low positive end-expiratory pressure for patients with acute respiratory distress syndrome in France (the LIVE study): a multicentre, single-blind, randomised controlled trial.

Constantin JM, Jabaudon M, Lefrant JY, Jaber S, Quenot JP, Langeron O, Ferrandière M, Grelon F, Seguin P, Ichai C, Veber B, Souweine B, Uberti T, Lasocki S, Legay F, Leone M, Eisenmann N, Dahyot-Fizelier C, Dupont H, Asehnoune K, Sossou A, Chanques G, Muller L, Bazin JE, Monsel A, Borao L, Garcier JM, Rouby JJ, Pereira B, Futier E; AZUREA Network.

Lancet Respir Med. 2019 Aug 6. pii: S2213-2600(19)30138-9. doi: 10.1016/S2213-2600(19)30138-9. [Epub ahead of print]


T regulatory cells activation and distribution are modified in critically ill patients with acute respiratory distress syndrome: A prospective single-centre observational study.

Halter S, Aimade L, Barbié M, Brisson H, Rouby JJ, Langeron O, Klatzmann D, Rosenzwajg M, Monsel A.

Anaesth Crit Care Pain Med. 2019 Jul 30. pii: S2352-5568(19)30210-3. doi: 10.1016/j.accpm.2019.07.014. [Epub ahead of print]


Nebulized Antibiotics: Epithelial Lining Fluid Concentrations Overestimate Lung Tissue Concentrations.

Rouby JJ, Monsel A.

Anesthesiology. 2019 Aug;131(2):229-232. doi: 10.1097/ALN.0000000000002824. No abstract available.


Trendelenburg Position and Morbid Obesity: A Respiratory Challenge for the Anesthesiologist.

Rouby JJ, Monsel A, Lucidarme O, Constantin JM.

Anesthesiology. 2019 Jul;131(1):10-13. doi: 10.1097/ALN.0000000000002779. No abstract available.


Colour Doppler ultrasound after major cardiac surgery improves diagnostic accuracy of the pulmonary infection score in acute respiratory failure: A prospective observational study.

Dureau P, Bouglé A, Melac AT, Ait Hamou N, Arbelot C, Ben Hassen K, Charfeddine A, Deransy R, Arcile G, Rouby JJ, Granger B, Amour J.

Eur J Anaesthesiol. 2019 Sep;36(9):676-682. doi: 10.1097/EJA.0000000000001022.


Agitated saline bubble-enhanced ultrasound for the positioning of cuffed, tunneled dialysis catheters in patients with end-stage renal disease.

Passos RDH, Ribeiro M, da Conceição LFMR, Ramos JGR, Ribeiro JC, Batista PBP, Dutra MMD, Rouby JJ.

J Vasc Access. 2019 Jul;20(4):362-367. doi: 10.1177/1129729818806121. Epub 2018 Oct 25.


Training for Lung Ultrasound Score Measurement in Critically Ill Patients.

Rouby JJ, Arbelot C, Gao Y, Zhang M, Lv J, An Y, Wang C, Bin D, Barbas CSV, Dexheimer Neto FL, Prior Caltabeloti F, Lima E, Cebey A, Perbet S, Constantin JM; APECHO study group.

Am J Respir Crit Care Med. 2018 Mar 20. doi: 10.1164/rccm.201802-0227LE. [Epub ahead of print] No abstract available.


The authors reply.

Monsel A, Le Corre M, Deransy R, Langeron O, Rouby JJ.

Crit Care Med. 2018 Apr;46(4):e343. doi: 10.1097/CCM.0000000000002983. No abstract available.


Influence of diluent volume of colistimethate sodium on aerosol characteristics and pharmacokinetics in ventilator-associated pneumonia caused by MDR bacteria.

Bihan K, Zahr N, Becquemin MH, Lu X, Bertholon JF, Vezinet C, Arbelot C, Monsel A, Rouby JJ, Langeron O, Lu Q.

J Antimicrob Chemother. 2018 Jun 1;73(6):1639-1646. doi: 10.1093/jac/dky044.


Agitated Saline Bubble-Enhanced Ultrasound for Assessing Appropriate Position of Hemodialysis Central Venous Catheter in Critically Ill Patients.

da Hora Passos R, Ribeiro M, Neves J, Rosa Ramos JG, Lima Oliveira AV, Barreto Z, Ferreira R, Gomes C, Pena Batista PB, Rouby JJ.

Kidney Int Rep. 2017 Apr 7;2(5):952-956. doi: 10.1016/j.ekir.2017.03.010. eCollection 2017 Sep. No abstract available.


Sevoflurane in Acute Respiratory Distress Syndrome: Are Lung Protection and Anesthesia Depth Influenced by Pulmonary Morphology?

Riché A, Adam N, Monsel A, Xia J, Langeron O, Rouby JJ.

Am J Respir Crit Care Med. 2018 Mar 15;197(6):830-832. doi: 10.1164/rccm.201709-1864LE. No abstract available.


Modification of Tracheal Cuff Shape and Continuous Cuff Pressure Control to Prevent Microaspiration in an Ex Vivo Pig Tracheal Two-Lung Model.

Monsel A, Le Corre M, Deransy R, Brisson H, Arbelot C, Lu Q, Golmard JL, Langeron O, Rouby JJ.

Crit Care Med. 2017 Dec;45(12):e1262-e1269. doi: 10.1097/CCM.0000000000002764.


Use of nebulized antimicrobials for the treatment of respiratory infections in invasively mechanically ventilated adults: a position paper from the European Society of Clinical Microbiology and Infectious Diseases.

Rello J, Solé-Lleonart C, Rouby JJ, Chastre J, Blot S, Poulakou G, Luyt CE, Riera J, Palmer LB, Pereira JM, Felton T, Dhanani J, Bassetti M, Welte T, Roberts JA.

Clin Microbiol Infect. 2017 Sep;23(9):629-639. doi: 10.1016/j.cmi.2017.04.011. Epub 2017 Apr 13.


Key considerations on nebulization of antimicrobial agents to mechanically ventilated patients.

Rello J, Rouby JJ, Sole-Lleonart C, Chastre J, Blot S, Luyt CE, Riera J, Vos MC, Monsel A, Dhanani J, Roberts JA.

Clin Microbiol Infect. 2017 Sep;23(9):640-646. doi: 10.1016/j.cmi.2017.03.018. Epub 2017 Mar 25.


Impact of graft preservation solutions for liver transplantation on early cytokine release and postoperative organ dysfunctions. A pilot study.

Brisson H, Arbelot C, Monsel A, Parisot C, Girard M, Savier E, Vezinet C, Lu Q, Vaillant JC, Golmard JL, Gorochov G, Langeron O, Rouby JJ; Members of the Pitié-Salpêtrière Liver Transplantation Study Group.

Clin Res Hepatol Gastroenterol. 2017 Oct;41(5):564-574. doi: 10.1016/j.clinre.2016.12.011. Epub 2017 Mar 18.


Nebulization of Antiinfective Agents in Invasively Mechanically Ventilated Adults: A Systematic Review and Meta-analysis.

Solé-Lleonart C, Rouby JJ, Blot S, Poulakou G, Chastre J, Palmer LB, Bassetti M, Luyt CE, Pereira JM, Riera J, Felton T, Dhanani J, Welte T, Garcia-Alamino JM, Roberts JA, Rello J.

Anesthesiology. 2017 May;126(5):890-908. doi: 10.1097/ALN.0000000000001570. Review.


Looking closer at acute respiratory distress syndrome: the role of advanced imaging techniques.

Bellani G, Rouby JJ, Constantin JM, Pesenti A.

Curr Opin Crit Care. 2017 Feb;23(1):30-37. doi: 10.1097/MCC.0000000000000380. Review.


In Reply.

Monsel A, Le Corre M, Brisson H, Arbelot C, Vezinet C, Fléron MH, Lu Q, Langeron O, Rouby JJ.

Anesthesiology. 2016 Nov;125(5):1076-1077. No abstract available.


Determination of Colistin and Colistimethate Levels in Human Plasma and Urine by High-Performance Liquid Chromatography-Tandem Mass Spectrometry.

Bihan K, Lu Q, Enjalbert M, Apparuit M, Langeron O, Rouby JJ, Funck-Brentano C, Zahr N.

Ther Drug Monit. 2016 Dec;38(6):796-803.


Ultrasound assessment of lung consolidation and reaeration after pleural effusion drainage in patients with Acute Respiratory Distress Syndrome: a pilot study.

Chinardet B, Brisson H, Arbelot C, Langeron O, Rouby JJ, Lu Q.

Acta Anaesthesiol Belg. 2016;67(1):29-35.


Lung ultrasonography for assessment of oxygenation response to prone position ventilation in ARDS.

Haddam M, Zieleskiewicz L, Perbet S, Baldovini A, Guervilly C, Arbelot C, Noel A, Vigne C, Hammad E, Antonini F, Lehingue S, Peytel E, Lu Q, Bouhemad B, Golmard JL, Langeron O, Martin C, Muller L, Rouby JJ, Constantin JM, Papazian L, Leone M; CAR’Echo Collaborative Network; AzuRea Collaborative Network.

Intensive Care Med. 2016 Oct;42(10):1546-1556. doi: 10.1007/s00134-016-4411-7. Epub 2016 Jun 20.


Lung ultrasound: a useful tool in the weaning process?

Caltabeloti FP, Rouby JJ.

Rev Bras Ter Intensiva. 2016 Jan-Mar;28(1):5-7. doi: 10.5935/0103-507X.20160002. English, Portuguese. No abstract available.


Elevated Plasma Levels of sRAGE Are Associated With Nonfocal CT-Based Lung Imaging in Patients With ARDS: A Prospective Multicenter Study.

Mrozek S, Jabaudon M, Jaber S, Paugam-Burtz C, Lefrant JY, Rouby JJ, Asehnoune K, Allaouchiche B, Baldesi O, Leone M, Lu Q, Bazin JE, Roszyk L, Sapin V, Futier E, Pereira B, Constantin JM; Azurea network.

Chest. 2016 Nov;150(5):998-1007. doi: 10.1016/j.chest.2016.03.016. Epub 2016 Mar 23.


Intratracheal Administration of Antimicrobial Agents in Mechanically Ventilated Adults: An International Survey on Delivery Practices and Safety.

Solé-Lleonart C, Rouby JJ, Chastre J, Poulakou G, Palmer LB, Blot S, Felton T, Bassetti M, Luyt CE, Pereira JM, Riera J, Welte T, Roberts JA, Rello J.

Respir Care. 2016 Aug;61(8):1008-14. doi: 10.4187/respcare.04519. Epub 2016 Mar 8.


Tapered-cuff Endotracheal Tube Does Not Prevent Early Postoperative Pneumonia Compared with Spherical-cuff Endotracheal Tube after Major Vascular Surgery: A Randomized Controlled Trial.

Monsel A, Lu Q, Le Corre M, Brisson H, Arbelot C, Vezinet C, Fléron MH, Ibanez-Estève C, Zerimech F, Balduyck M, Dexheimer F, Wang C, Langeron O, Rouby JJ, Bodin L, Deransy R, Garçon P, Douiri H, Khalifa I, Pons A, Gu WJ, Koskas F, Gaudric J; TETRIS Study Group.

Anesthesiology. 2016 May;124(5):1041-52. doi: 10.1097/ALN.0000000000001053.


Global survey on nebulization of antimicrobial agents in mechanically ventilated patients: a call for international guidelines.

Solé-Lleonart C, Roberts JA, Chastre J, Poulakou G, Palmer LB, Blot S, Felton T, Bassetti M, Luyt CE, Pereira JM, Riera J, Welte T, Qiu H, Rouby JJ, Rello J; ESGCIP Investigators.

Clin Microbiol Infect. 2016 Apr;22(4):359-364. doi: 10.1016/j.cmi.2015.12.016. Epub 2015 Dec 23.


Could the DiversiLab® semi-automated repetitive-sequence-based PCR be an acceptable technique for typing isolates of Pseudomonas aeruginosa? An answer from our experience and a review of the literature.

Brossier F, Micaelo M, Luyt CE, Lu Q, Chastre J, Arbelot C, Trouillet JL, Combes A, Rouby JJ, Jarlier V, Aubry A.

Can J Microbiol. 2015 Dec;61(12):903-12. doi: 10.1139/cjm-2015-0372. Epub 2015 Sep 10.


Therapeutic Effects of Human Mesenchymal Stem Cell-derived Microvesicles in Severe Pneumonia in Mice.

Monsel A, Zhu YG, Gennai S, Hao Q, Hu S, Rouby JJ, Rosenzwajg M, Matthay MA, Lee JW.

Am J Respir Crit Care Med. 2015 Aug 1;192(3):324-36. doi: 10.1164/rccm.201410-1765OC.


First experience of liver transplantation with type 2 donation after cardiac death in France.

Savier E, Dondero F, Vibert E, Eyraud D, Brisson H, Riou B, Fieux F, Naili-Kortaia S, Castaing D, Rouby JJ, Langeron O, Dokmak S, Hannoun L, Vaillant JC; Donation After Cardiac Death Study Group.

Liver Transpl. 2015 May;21(5):631-43. doi: 10.1002/lt.24107.


Early fluid loading in acute respiratory distress syndrome with septic shock deteriorates lung aeration without impairing arterial oxygenation: a lung ultrasound observational study.

Caltabeloti F, Monsel A, Arbelot C, Brisson H, Lu Q, Gu WJ, Zhou GJ, Auler JO, Rouby JJ.

Crit Care. 2014 May 6;18(3):R91. doi: 10.1186/cc13859.


Assessment of panobacumab as adjunctive immunotherapy for the treatment of nosocomial Pseudomonas aeruginosa pneumonia.

Que YA, Lazar H, Wolff M, François B, Laterre PF, Mercier E, Garbino J, Pagani JL, Revelly JP, Mus E, Perez A, Tamm M, Rouby JJ, Lu Q, Chastre J, Eggimann P.

Eur J Clin Microbiol Infect Dis. 2014 Oct;33(10):1861-7. doi: 10.1007/s10096-014-2156-1. Epub 2014 May 24.


Ischaemic colitis: indications, extent, and results of standardized emergency surgery.

Moszkowicz D, Trésallet C, Mariani A, Lefevre JH, Godiris-Petit G, Noullet S, Rouby JJ, Menegaux F.

Dig Liver Dis. 2014 Jun;46(6):505-11. doi: 10.1016/j.dld.2014.02.013. Epub 2014 Mar 18.


Pseudomonas aeruginosa serotypes in nosocomial pneumonia: prevalence and clinical outcomes.

Lu Q, Eggimann P, Luyt CE, Wolff M, Tamm M, François B, Mercier E, Garbino J, Laterre PF, Koch H, Gafner V, Rudolf MP, Mus E, Perez A, Lazar H, Chastre J, Rouby JJ.

Crit Care. 2014 Jan 15;18(1):R17. doi: 10.1186/cc13697.


Imipenem, meropenem, or doripenem to treat patients with Pseudomonas aeruginosa ventilator-associated pneumonia.

Luyt CE, Aubry A, Lu Q, Micaelo M, Bréchot N, Brossier F, Brisson H, Rouby JJ, Trouillet JL, Combes A, Jarlier V, Chastre J.

Antimicrob Agents Chemother. 2014;58(3):1372-80. doi: 10.1128/AAC.02109-13. Epub 2013 Dec 16.


Doppler study of the effects of inhaled nitric oxide and intravenous almitrine on regional pulmonary blood flows in patients with acute lung injury.

Bouhemad B, Barbry T, Soummer A, Lu Q, Rouby JJ.

Minerva Anestesiol. 2014 May;80(5):517-25. Epub 2013 Dec 4.


Cardiac compression of lung lower lobes after coronary artery bypass graft with cardiopulmonary bypass.

Neves FH, Carmona MJ, Auler JO Jr, Rodrigues RR, Rouby JJ, Malbouisson LM.

PLoS One. 2013 Nov 11;8(11):e78643. doi: 10.1371/journal.pone.0078643. eCollection 2013.


[Support for the families of multi-trauma patients in intensive care].

Kacer S, Rouby JJ, Thomas M.

Soins. 2013 Sep;(778):41-2. French.


Plasma levels of sRAGE, loss of aeration and weaning failure in ICU patients: a prospective observational multicenter study.

Jabaudon M, Perbet S, Pereira B, Soummer A, Roszyk L, Guérin R, Futier E, Lu Q, Bazin JE, Sapin V, Rouby JJ, Constantin JM.

PLoS One. 2013 May 27;8(5):e64083. doi: 10.1371/journal.pone.0064083. Print 2013.


Measurement of alveolar recruitment at the bedside: the beginning of a new era in respiratory monitoring?

Rouby JJ, Arbelot C, Brisson H, Lu Q, Bouhemad B.

Respir Care. 2013 Mar;58(3):539-42. doi: 10.4187/respcare.02363. No abstract available.


Automated sedation outperforms manual administration of propofol and remifentanil in critically ill patients with deep sedation: a randomized phase II trial.

Le Guen M, Liu N, Bourgeois E, Chazot T, Sessler DI, Rouby JJ, Fischler M.

Intensive Care Med. 2013 Mar;39(3):454-62. doi: 10.1007/s00134-012-2762-2. Epub 2012 Dec 6.


Aerosolized antibiotics for ventilator-associated pneumonia: lessons from experimental studies.

Rouby JJ, Bouhemad B, Monsel A, Brisson H, Arbelot C, Lu Q; Nebulized Antibiotics Study Group.

Anesthesiology. 2012 Dec;117(6):1364-80. doi: 10.1097/ALN.0b013e3182755d7a. Review.


Effects of positive end-expiratory pressure titration and recruitment maneuver on lung inflammation and hyperinflation in experimental acid aspiration-induced lung injury.

Ambrosio AM, Luo R, Fantoni DT, Gutierres C, Lu Q, Gu WJ, Otsuki DA, Malbouisson LM, Auler JO Jr, Rouby JJ; Experimental ARDS Study Group.

Anesthesiology. 2012 Dec;117(6):1322-34. doi: 10.1097/ALN.0b013e31827542aa.


Efficacy of high-dose nebulized colistin in ventilator-associated pneumonia caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii.

Lu Q, Luo R, Bodin L, Yang J, Zahr N, Aubry A, Golmard JL, Rouby JJ; Nebulized Antibiotics Study Group.

Anesthesiology. 2012 Dec;117(6):1335-47. doi: 10.1097/ALN.0b013e31827515de.


Self-perception of knowledge and confidence in performing basic life support among medical students.

Freund Y, Duchateau FX, Baker EC, Goulet H, Carreira S, Schmidt M, Riou B, Rouby JJ, Duguet A.

Eur J Emerg Med. 2013 Jun;20(3):193-6. doi: 10.1097/MEJ.0b013e328355fd59.


Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*.

Soummer A, Perbet S, Brisson H, Arbelot C, Constantin JM, Lu Q, Rouby JJ; Lung Ultrasound Study Group.

Crit Care Med. 2012 Jul;40(7):2064-72. doi: 10.1097/CCM.0b013e31824e68ae.


International evidence-based recommendations for point-of-care lung ultrasound.

Volpicelli G, Elbarbary M, Blaivas M, Lichtenstein DA, Mathis G, Kirkpatrick AW, Melniker L, Gargani L, Noble VE, Via G, Dean A, Tsung JW, Soldati G, Copetti R, Bouhemad B, Reissig A, Agricola E, Rouby JJ, Arbelot C, Liteplo A, Sargsyan A, Silva F, Hoppmann R, Breitkreutz R, Seibel A, Neri L, Storti E, Petrovic T; International Liaison Committee on Lung Ultrasound (ILC-LUS) for International Consensus Conference on Lung Ultrasound (ICC-LUS).

Intensive Care Med. 2012 Apr;38(4):577-91. doi: 10.1007/s00134-012-2513-4. Epub 2012 Mar 6. Review.


Accuracy and precision of end-expiratory lung-volume measurements by automated nitrogen washout/washin technique in patients with acute respiratory distress syndrome.

Dellamonica J, Lerolle N, Sargentini C, Beduneau G, Di Marco F, Mercat A, Richard JC, Diehl JL, Mancebo J, Rouby JJ, Lu Q, Bernardin G, Brochard L.

Crit Care. 2011;15(6):R294. doi: 10.1186/cc10587. Epub 2011 Dec 7.


Extracorporeal membrane oxygenation as a bridge to liver transplantation for acute respiratory distress syndrome-induced life-threatening hypoxaemia aggravated by hepatopulmonary syndrome.

Monsel A, Mal H, Brisson H, Luo R, Eyraud D, Vézinet C, Do CH, Lu Q, Vaillant JC, Hannoun L, Houssel P, Durand F, Rouby JJ.

Crit Care. 2011;15(5):R234. doi: 10.1186/cc10476. Epub 2011 Sep 29.


Multidrug-resistant Acinetobacter baumannii infections in three returning travelers evacuated from Algeria, Thailand, and Turkey after hospitalization in local intensive care units.

Hussenet C, Jauréguiberry S, Robert J, Rouby JJ, Bricaire F, Caumes E.

J Travel Med. 2011 Sep-Oct;18(5):358-60. doi: 10.1111/j.1708-8305.2011.00546.x. Epub 2011 Aug 8.


PEEP-induced changes in lung volume in acute respiratory distress syndrome. Two methods to estimate alveolar recruitment.

Dellamonica J, Lerolle N, Sargentini C, Beduneau G, Di Marco F, Mercat A, Richard JC, Diehl JL, Mancebo J, Rouby JJ, Lu Q, Bernardin G, Brochard L.

Intensive Care Med. 2011 Oct;37(10):1595-604. doi: 10.1007/s00134-011-2333-y. Epub 2011 Aug 25.


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