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Mediator complex subunit Med12 regulates cardiac jelly development and AV valve formation in zebrafish.

Segert J, Schneider I, Berger IM, Rottbauer W, Just S.

Prog Biophys Mol Biol. 2018 Jul 20. pii: S0079-6107(18)30023-3. doi: 10.1016/j.pbiomolbio.2018.07.010. [Epub ahead of print]


Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo.

Kustermann M, Manta L, Paone C, Kustermann J, Lausser L, Wiesner C, Eichinger L, Clemen CS, Schröder R, Kestler HA, Sandri M, Rottbauer W, Just S.

Autophagy. 2018 Jul 16. doi: 10.1080/15548627.2018.1491491. [Epub ahead of print]


Comparing Cardiac Magnetic Resonance-Guided Versus Angiography-Guided Treatment of Patients With Stable Coronary Artery Disease: Results From a Prospective Randomized Controlled Trial.

Buckert D, Witzel S, Steinacker JM, Rottbauer W, Bernhardt P.

JACC Cardiovasc Imaging. 2018 Jul;11(7):987-996. doi: 10.1016/j.jcmg.2018.05.007.


Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation.

Vernikouskaya I, Rottbauer W, Seeger J, Gonska B, Wöhrle J, Rasche V.

J Vis Exp. 2018 Jun 3;(136). doi: 10.3791/57858.


Genetics of Cardiovascular Disease: Fishing for Causality.

Paone C, Diofano F, Park DD, Rottbauer W, Just S.

Front Cardiovasc Med. 2018 Jun 1;5:60. doi: 10.3389/fcvm.2018.00060. eCollection 2018. Review.


Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish.

Pott A, Bock S, Berger IM, Frese K, Dahme T, Keßler M, Rinné S, Decher N, Just S, Rottbauer W.

J Mol Cell Cardiol. 2018 Jul;120:42-52. doi: 10.1016/j.yjmcc.2018.05.005. Epub 2018 May 8.


A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations.

Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W.

Neuromuscul Disord. 2018 Jun;28(6):521-531. doi: 10.1016/j.nmd.2018.03.001. Epub 2018 Mar 15.


Antithrombotic therapy in patients with non-valvular atrial fibrillation undergoing percutaneous coronary intervention: should we change our practice after the PIONEER AF-PCI and RE-DUAL PCI trials?

Duerschmied D, Brachmann J, Darius H, Frey N, Katus HA, Rottbauer W, Schäfer A, Thiele H, Bode C, Zeymer U.

Clin Res Cardiol. 2018 Jul;107(7):533-538. doi: 10.1007/s00392-018-1242-2. Epub 2018 Apr 20.


Predictors of early scaffold thrombosis: results from the multicenter prospective German-Austrian ABSORB RegIstRy.

Wöhrle J, Nef HM, Naber C, Achenbach S, Riemer T, Mehilli J, Münzel T, Schneider S, Markovic S, Seeger J, Rottbauer W, Pfannebecker T, Richardt G, Zahn R, Gori T, Kastner J, Schmermund A, Hamm CW; GABI-R Study Group.

Coron Artery Dis. 2018 Aug;29(5):389-396. doi: 10.1097/MCA.0000000000000618.


Rumpel-Leede Sign After Coronary Angiography.

Rattka M, Rottbauer W.

Dtsch Arztebl Int. 2018 Feb 9;115(6):82. doi: 10.3238/arztebl.2018.0082. No abstract available.


Patient-specific registration of 3D CT angiography (CTA) with X-ray fluoroscopy for image fusion during transcatheter aortic valve implantation (TAVI) increases performance of the procedure.

Vernikouskaya I, Rottbauer W, Seeger J, Gonska B, Rasche V, Wöhrle J.

Clin Res Cardiol. 2018 Jun;107(6):507-516. doi: 10.1007/s00392-018-1212-8. Epub 2018 Feb 16.


Time-to-isolation guided titration of freeze duration in 3rd generation short-tip cryoballoon pulmonary vein isolation - Comparable clinical outcome and shorter procedure duration.

Pott A, Kraft C, Stephan T, Petscher K, Rottbauer W, Dahme T.

Int J Cardiol. 2018 Mar 15;255:80-84. doi: 10.1016/j.ijcard.2017.11.039.


Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response.

Paone C, Rudeck S, Etard C, Strähle U, Rottbauer W, Just S.

Biochem Biophys Res Commun. 2018 Feb 5;496(2):339-345. doi: 10.1016/j.bbrc.2018.01.060. Epub 2018 Jan 10.


Author's reply.

Gonska B, Seeger J, Rottbauer W, Wöhrle J.

J Cardiol. 2018 Jun;71(6):598. doi: 10.1016/j.jjcc.2017.12.003. Epub 2018 Jan 6. No abstract available.


Percutaneous mitral valve repair with the MitraClip NT™ system in a patient presenting with prolonged cardiogenic shock.

Buckert D, Markovic S, Kunze M, Wöhrle J, Rottbauer W, Walcher D.

Clin Case Rep. 2017 Sep 23;5(11):1807-1810. doi: 10.1002/ccr3.930. eCollection 2017 Nov.


Transfemoral aortic valve implantation is more successful with the Edwards Sapien 3 compared with the Edwards XT for the treatment of symptomatic severe aortic stenosis.

Gonska B, Seeger J, Junker A, Rodewald C, Trepte U, Scharnbeck D, Rottbauer W, Wöhrle J.

Arch Cardiovasc Dis. 2017 Nov 8. pii: S1875-2136(17)30187-0. doi: 10.1016/j.acvd.2017.05.012. [Epub ahead of print]


Myocardial strain characteristics and outcomes after transcatheter aortic valve replacement.

Buckert D, Tibi R, Cieslik M, Radermacher M, Qu YY, Rasche V, Bernhardt P, Hombach V, Rottbauer W, Wöhrle J.

Cardiol J. 2018;25(2):203-212. doi: 10.5603/CJ.a2017.0121. Epub 2017 Oct 24.


Cardiac Findings in Amyotrophic Lateral Sclerosis: A Magnetic Resonance Imaging Study.

Rosenbohm A, Schmid B, Buckert D, Rottbauer W, Kassubek J, Ludolph AC, Bernhardt P.

Front Neurol. 2017 Sep 27;8:479. doi: 10.3389/fneur.2017.00479. eCollection 2017.


Predictors of permanent pacemaker implantation after transfemoral aortic valve implantation with the Lotus valve.

Keßler M, Gonska B, Seeger J, Rottbauer W, Wöhrle J.

Am Heart J. 2017 Oct;192:57-63. doi: 10.1016/j.ahj.2017.07.011. Epub 2017 Jul 19.


Image-guidance for transcatheter aortic valve implantation (TAVI) and cerebral embolic protection.

Vernikouskaya I, Rottbauer W, Gonska B, Rodewald C, Seeger J, Rasche V, Wöhrle J.

Int J Cardiol. 2017 Dec 15;249:90-95. doi: 10.1016/j.ijcard.2017.09.158. Epub 2017 Sep 18.


Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement Significantly Reduces Death and Stroke Compared With Unprotected Procedures.

Seeger J, Gonska B, Otto M, Rottbauer W, Wöhrle J.

JACC Cardiovasc Interv. 2017 Nov 27;10(22):2297-2303. doi: 10.1016/j.jcin.2017.06.037. Epub 2017 Sep 13.


Validation of a New System Using Tracheal Body Sound and Movement Data for Automated Apnea-Hypopnea Index Estimation.

Kalkbrenner C, Eichenlaub M, Rüdiger S, Kropf-Sanchen C, Brucher R, Rottbauer W.

J Clin Sleep Med. 2017 Oct 15;13(10):1123-1130. doi: 10.5664/jcsm.6752.


Apnea and heart rate detection from tracheal body sounds for the diagnosis of sleep-related breathing disorders.

Kalkbrenner C, Eichenlaub M, Rüdiger S, Kropf-Sanchen C, Rottbauer W, Brucher R.

Med Biol Eng Comput. 2018 Apr;56(4):671-681. doi: 10.1007/s11517-017-1706-y. Epub 2017 Aug 29.


Longitudinal strain assessed by cardiac magnetic resonance correlates to hemodynamic findings in patients with severe aortic stenosis and predicts positive remodeling after transcatheter aortic valve replacement.

Buckert D, Cieslik M, Tibi R, Radermacher M, Rasche V, Bernhardt P, Hombach V, Rottbauer W, Wöhrle J.

Clin Res Cardiol. 2018 Jan;107(1):20-29. doi: 10.1007/s00392-017-1153-7. Epub 2017 Aug 14.


Screening for infectious diseases among asylum seekers newly arrived in Germany in 2015: a systematic single-centre analysis.

Kortas AZ, Polenz J, von Hayek J, Rüdiger S, Rottbauer W, Storr U, Wibmer T.

Public Health. 2017 Dec;153:1-8. doi: 10.1016/j.puhe.2017.07.011. Epub 2017 Aug 8.


Magnetic resonance Adenosine perfusion imaging as Gatekeeper of invasive coronary intervention (MAGnet): study protocol for a randomized controlled trial.

Buckert D, Witzel S, Cieslik M, Tibi R, Rottbauer W, Bernhardt P.

Trials. 2017 Jul 28;18(1):358. doi: 10.1186/s13063-017-2101-6.


Angiographic and clinical outcomes after recanalization of coronary chronic total occlusions with the Orsiro sirolimus-eluting stent compared with the resolute zotarolimus-eluting stent.

Markovic S, Lützner M, Dragomir S, Rottbauer W, Wöhrle J.

Coron Artery Dis. 2017 Aug;28(5):376-380. doi: 10.1097/MCA.0000000000000470.


New generation devices for transfemoral transcatheter aortic valve replacement are superior compared with last generation devices with respect to VARC-2 outcome.

Seeger J, Gonska B, Rottbauer W, Wöhrle J.

Cardiovasc Interv Ther. 2018 Jul;33(3):247-255. doi: 10.1007/s12928-017-0477-6. Epub 2017 Jun 22.


Long-term clinical results of bioresorbable absorb scaffolds using the PSP-technique in patients with and without diabetes.

Markovic S, Kugler C, Rottbauer W, Wöhrle J.

J Interv Cardiol. 2017 Aug;30(4):325-330. doi: 10.1111/joic.12392. Epub 2017 Jun 1.


Outcome With the Repositionable and Retrievable Boston Scientific Lotus Valve Compared With the Balloon-Expandable Edwards Sapien 3 Valve in Patients Undergoing Transfemoral Aortic Valve Replacement.

Seeger J, Gonska B, Rottbauer W, Wöhrle J.

Circ Cardiovasc Interv. 2017 Jun;10(6). pii: e004670. doi: 10.1161/CIRCINTERVENTIONS.116.004670.


First experience with the Watchman FLX occluder for percutaneous left atrial appendage closure.

Seeger J, Birkemeyer R, Rottbauer W, Wöhrle J.

Cardiovasc Revasc Med. 2017 Oct - Nov;18(7):512-516. doi: 10.1016/j.carrev.2017.04.018. Epub 2017 Apr 29.


Reply: Apixaban in Patients With Atrial Fibrillation After Transfemoral Aortic Valve Replacement.

Seeger J, Rottbauer W, Wöhrle J.

JACC Cardiovasc Interv. 2017 May 8;10(9):965-966. doi: 10.1016/j.jcin.2017.02.034. No abstract available.


Percutaneous Mitral Valve Repair With the MitraClip in Primary Compared With Secondary Mitral Valve Regurgitation Using the Mitral Valve Academic Research Consortium Criteria.

Seeger J, Müller P, Gonska B, Scharnbeck D, Markovic S, Walcher D, Rottbauer W, Wöhrle J.

J Invasive Cardiol. 2017 Apr;29(4):145-150.


Cardiac magnetic resonance imaging derived quantification of myocardial ischemia and scar improves risk stratification and patient management in stable coronary artery disease.

Buckert D, Cieslik M, Tibi R, Radermacher M, Rottbauer W, Bernhardt P.

Cardiol J. 2017;24(3):293-304. doi: 10.5603/CJ.a2017.0036. Epub 2017 Mar 29.


Assessment of Longitudinal Reproducibility of Mice LV Function Parameters at 11.7 T Derived from Self-Gated CINE MRI.

Zuo Z, Subgang A, Abaei A, Rottbauer W, Stiller D, Ma G, Rasche V.

Biomed Res Int. 2017;2017:8392952. doi: 10.1155/2017/8392952. Epub 2017 Feb 22.


Predictors for permanent pacemaker implantation in patients undergoing transfemoral aortic valve implantation with the Edwards Sapien 3 valve.

Gonska B, Seeger J, Keßler M, von Keil A, Rottbauer W, Wöhrle J.

Clin Res Cardiol. 2017 Aug;106(8):590-597. doi: 10.1007/s00392-017-1093-2. Epub 2017 Mar 10.


T2-prepared segmented 3D-gradient-echo for fast T2-weighted high-resolution three-dimensional imaging of the carotid artery wall at 3T: a feasibility study.

Zhu J, Bornstedt A, Merkle N, Liu N, Rottbauer W, Ma G, Rasche V.

Biomed Eng Online. 2016 Dec 28;15(Suppl 2):165. doi: 10.1186/s12938-016-0276-9.


Apixaban in Patients With Atrial Fibrillation After Transfemoral Aortic Valve Replacement.

Seeger J, Gonska B, Rodewald C, Rottbauer W, Wöhrle J.

JACC Cardiovasc Interv. 2017 Jan 9;10(1):66-74. doi: 10.1016/j.jcin.2016.10.023.


Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish.

Just S, Raphel L, Berger IM, Bühler A, Keßler M, Rottbauer W.

PLoS One. 2016 Dec 1;11(12):e0167306. doi: 10.1371/journal.pone.0167306. eCollection 2016.


Bioresorbable scaffolds compared with everolimus-eluting stents for the treatment of chronic coronary total occlusion: clinical and angiographic results of a matched paired comparison.

Kugler C, Markovic S, Rottbauer W, Wöhrle J.

Coron Artery Dis. 2017 Mar;28(2):120-125. doi: 10.1097/MCA.0000000000000449.


Transfemoral valve-in-valve implantation for degenerated bioprosthetic aortic valves using the new balloon-expandable Edwards Sapien 3 valve.

Gonska B, Seeger J, Rodewald C, Scharnbeck D, Rottbauer W, Wöhrle J.

Catheter Cardiovasc Interv. 2016 Oct;88(4):636-643. doi: 10.1002/ccd.26565. Epub 2016 May 3.


Left ventricular ejection fraction and presence of myocardial necrosis assessed by cardiac magnetic resonance imaging correctly risk stratify patients with stable coronary artery disease: a multi-center all-comers trial.

Buckert D, Kelle S, Buss S, Korosoglou G, Gebker R, Birkemeyer R, Rottbauer W, Katus H, Pieske B, Bernhardt P.

Clin Res Cardiol. 2017 Mar;106(3):219-229. doi: 10.1007/s00392-016-1042-5. Epub 2016 Oct 13.


Clinical outcome of 2nd generation cryoballoon pulmonary vein isolation in patients over 75 years of age.

Pott A, Messemer M, Petscher K, Iturbe-Orbe M, Bothner C, Rottbauer W, Dahme T.

J Cardiol. 2017 Jan;69(1):24-29. doi: 10.1016/j.jjcc.2016.07.020. Epub 2016 Sep 17.


The balloon-expandable Edwards Sapien 3 valve is superior to the self-expanding Medtronic CoreValve in patients with severe aortic stenosis undergoing transfemoral aortic valve implantation.

Gonska B, Seeger J, Baarts J, Rodewald C, Scharnbeck D, Rottbauer W, Wöhrle J.

J Cardiol. 2017 Jun;69(6):877-882. doi: 10.1016/j.jjcc.2016.08.008. Epub 2016 Sep 7.


Impact of suture mediated femoral access site closure with the Prostar XL compared to the ProGlide system on outcome in transfemoral aortic valve implantation.

Seeger J, Gonska B, Rodewald C, Rottbauer W, Wöhrle J.

Int J Cardiol. 2016 Nov 15;223:564-567. doi: 10.1016/j.ijcard.2016.08.193. Epub 2016 Aug 17.


Transfemoral aortic valve implantation with the repositionable Lotus valve for treatment of patients with symptomatic severe aortic stenosis: results from a single-centre experience.

Wöhrle J, Gonska B, Rodewald C, Seeger J, Scharnbeck D, Rottbauer W.

EuroIntervention. 2016 Aug 20;12(6):760-7. doi: 10.4244/EIJV12I6A124.


Increased rate of observed real-time pulmonary vein isolation with third-generation short-tip cryoballoon.

Pott A, Petscher K, Messemer M, Rottbauer W, Dahme T.

J Interv Card Electrophysiol. 2016 Dec;47(3):333-339. Epub 2016 Jul 23.


The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation.

Just S, Hirth S, Berger IM, Fishman MC, Rottbauer W.

Biochem Biophys Res Commun. 2016 Sep 2;477(4):581-588. doi: 10.1016/j.bbrc.2016.06.088. Epub 2016 Jun 22.


A compact unc45b-promoter drives muscle-specific expression in zebrafish and mouse.

Rudeck S, Etard C, Khan MM, Rottbauer W, Rudolf R, Strähle U, Just S.

Genesis. 2016 Aug;54(8):431-8. doi: 10.1002/dvg.22953. Epub 2016 Jul 9.


Bioresorbable polymer sirolimus-eluting coronary stent compared with permanent polymer everolimus-eluting coronary stent implantation for treatment of small vessel coronary artery disease: CENTURY II trial.

Wöhrle J, Markovic S, Rottbauer W, Muramatsu T, Kadota K, Vázquez-González N, Odenstedt J, Serra A, Antoniucci D, Varenne O, Saito S, Wijns W.

EuroIntervention. 2016 Jun 12;12(2):e167-74. doi: 10.4244/EIJV12I2A30.

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