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Items: 1 to 50 of 243

1.

Profibrotic epithelial phenotype: a central role for MRTF and TAZ.

Bialik JF, Ding M, Speight P, Dan Q, Miranda MZ, Di Ciano-Oliveira C, Kofler MM, Rotstein OD, Pedersen SF, Szászi K, Kapus A.

Sci Rep. 2019 Mar 13;9(1):4323. doi: 10.1038/s41598-019-40764-7.

2.

Nuclear Factor (Erythroid-Derived 2)-Like 2 Regulates the Hepatoprotective Effects of Remote Ischemic Conditioning in Hemorrhagic Shock.

Leung CH, Caldarone CA, Guan R, Wen XY, Ailenberg M, Kapus A, Szaszi K, Rotstein OD.

Antioxid Redox Signal. 2019 May 10;30(14):1760-1773. doi: 10.1089/ars.2018.7541. Epub 2018 Dec 20.

PMID:
30403148
3.

Postoperative ERAS Interventions Have the Greatest Impact on Optimal Recovery: Experience With Implementation of ERAS Across Multiple Hospitals.

Aarts MA, Rotstein OD, Pearsall EA, Victor JC, Okrainec A, McKenzie M, McCluskey SA, Conn LG, McLeod RS; iERAS group.

Ann Surg. 2018 Jun;267(6):992-997. doi: 10.1097/SLA.0000000000002632.

PMID:
29303803
4.

Cell confluence regulates claudin-2 expression: possible role for ZO-1 and Rac.

Amoozadeh Y, Anwer S, Dan Q, Venugopal S, Shi Y, Branchard E, Liedtke E, Ailenberg M, Rotstein OD, Kapus A, Szászi K.

Am J Physiol Cell Physiol. 2018 Mar 1;314(3):C366-C378. doi: 10.1152/ajpcell.00234.2017. Epub 2017 Nov 29.

5.

Longer-Duration Antimicrobial Therapy Does Not Prevent Treatment Failure in High-Risk Patients with Complicated Intra-Abdominal Infections.

Hassinger TE, Guidry CA, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Napolitano LM, Namias N, Miller PR, Dellinger EP, Coimbra R, Cocanour CS, Banton KL, Cuschieri J, Popovsky K, Sawyer RG.

Surg Infect (Larchmt). 2017 Aug/Sep;18(6):659-663. doi: 10.1089/sur.2017.084. Epub 2017 Jun 26.

6.

Age and Its Impact on Outcomes with Intra-Abdominal Infection.

Farmer D, Tessier JM, Sanders JM, Sawyer RG, Rotstein OD, Dellinger EP, Lipsett PA, Cuschieri J, Miller P, Cook CH, Guidry CA, Askari R, Moore BJ, Duane TM.

Surg Infect (Larchmt). 2017 Feb/Mar;18(2):77-82. doi: 10.1089/sur.2016.184. Epub 2016 Dec 22.

PMID:
28005468
7.

Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection.

Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K, Namias N.

Am Surg. 2016 Sep;82(9):860-6.

PMID:
27670577
8.

Percutaneously drained intra-abdominal infections do not require longer duration of antimicrobial therapy.

Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Coimbra R, Cook CH, Duane TM, OʼNeill PJ, Rotstein OD, Namias N.

J Trauma Acute Care Surg. 2016 Jul;81(1):108-13. doi: 10.1097/TA.0000000000001019.

PMID:
26953758
9.

Patients with Complicated Intra-Abdominal Infection Presenting with Sepsis Do Not Require Longer Duration of Antimicrobial Therapy.

Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Claridge JA, Cocanour CS, Coimbra R, Cook CH, Cuschieri J, Dellinger EP, Duane TM, Evans HL, Lipsett PA, Mazuski JE, Miller PR, O'Neill PJ, Rotstein OD, Namias N.

J Am Coll Surg. 2016 Apr;222(4):440-6. doi: 10.1016/j.jamcollsurg.2015.12.050. Epub 2016 Jan 14.

PMID:
26920994
10.

Early Cholecystectomy for Acute Cholecystitis Offers the Best Outcomes at the Least Cost: A Model-Based Cost-Utility Analysis.

de Mestral C, Hoch JS, Laupacis A, Wijeysundera HC, Rotstein OD, Alali AS, Nathens AB.

J Am Coll Surg. 2016 Feb;222(2):185-94. doi: 10.1016/j.jamcollsurg.2015.10.015. Epub 2015 Nov 25.

PMID:
26705901
11.

Reply to: "Early Cholecystectomy for Acute Cholecystitis, How Early Should It Be?".

de Mestral C, Rotstein OD, Nathens AB.

Ann Surg. 2016 Apr;263(4):e59. doi: 10.1097/SLA.0000000000001206. No abstract available.

PMID:
26692075
12.

Modified triple-layer peritoneal-aponeurotic transposition: A new strategy to close the "open abdomen".

Rezende-Neto JB, Angarita FA, Rizoli SB, Rotstein OD.

J Trauma Acute Care Surg. 2015 Oct;79(4):694-7. doi: 10.1097/TA.0000000000000817. No abstract available.

PMID:
26402547
13.

Sphingosine-1-Phosphate Signaling Regulates Myogenic Responsiveness in Human Resistance Arteries.

Hui S, Levy AS, Slack DL, Burnstein MJ, Errett L, Bonneau D, Latter D, Rotstein OD, Bolz SS, Lidington D, Voigtlaender-Bolz J.

PLoS One. 2015 Sep 14;10(9):e0138142. doi: 10.1371/journal.pone.0138142. eCollection 2015.

14.

Trial of short-course antimicrobial therapy for intraabdominal infection.

Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K; STOP-IT Trial Investigators.

N Engl J Med. 2015 May 21;372(21):1996-2005. doi: 10.1056/NEJMoa1411162. Erratum in: N Engl J Med. 2018 Jan 25;:null.

15.

Oxidative Stress Increases Surface Toll-Like Receptor 4 Expression in Murine Macrophages Via Ceramide Generation.

Tawadros PS, Powers KA, Ailenberg M, Birch SE, Marshall JC, Szaszi K, Kapus A, Rotstein OD.

Shock. 2015 Aug;44(2):157-65. doi: 10.1097/SHK.0000000000000392.

PMID:
25944793
16.

Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation.

Ailenberg M, Di Ciano-Oliveira C, Szaszi K, Dan Q, Rozycki M, Kapus A, Rotstein OD.

Br J Pharmacol. 2015 Aug;172(15):3748-63. doi: 10.1111/bph.13162. Epub 2015 May 15.

17.

Dr. Bernard Langer - inductee into the Canadian Medical Hall of Fame.

Greig PD, Rotstein OD.

Can J Surg. 2015 Apr;58(2):80-2.

18.

Inequity to the utilization of bariatric surgery: a systematic review and meta-analysis.

Bhogal SK, Reddigan JI, Rotstein OD, Cohen A, Glockler D, Tricco AC, Smylie JK, Glazer SA, Pennington J, Conn LG, Jackson TD.

Obes Surg. 2015 May;25(5):888-99. doi: 10.1007/s11695-015-1595-9. Review.

PMID:
25726318
19.

Circulating cytokines in predicting development of severe acute pancreatitis.

Rotstein OD.

Crit Care. 2014 Oct 20;18(5):575. doi: 10.1186/s13054-014-0575-0.

21.

Cancer patient experience with navigation service in an urban hospital setting: a qualitative study.

Gotlib Conn L, Hammond Mobilio M, Rotstein OD, Blacker S.

Eur J Cancer Care (Engl). 2016 Jan;25(1):132-40. doi: 10.1111/ecc.12247. Epub 2014 Oct 8.

PMID:
25295379
22.

Remote Ischemic Conditioning Prevents Lung and Liver Injury After Hemorrhagic Shock/Resuscitation: Potential Role of a Humoral Plasma Factor.

Leung CH, Caldarone CA, Wang F, Venkateswaran S, Ailenberg M, Vadasz B, Wen XY, Rotstein OD.

Ann Surg. 2015 Jun;261(6):1215-25. doi: 10.1097/SLA.0000000000000877.

PMID:
25185480
23.

Activated neutrophils induce epithelial cell apoptosis through oxidant-dependent tyrosine dephosphorylation of caspase-8.

Jia SH, Parodo J, Charbonney E, Tsang JLY, Jia SY, Rotstein OD, Kapus A, Marshall JC.

Am J Pathol. 2014 Apr;184(4):1030-1040. doi: 10.1016/j.ajpath.2013.12.031. Epub 2014 Feb 28.

24.

Neuroanatomical correlates of laparoscopic surgery training.

Bahrami P, Graham SJ, Grantcharov TP, Cusimano MD, Rotstein OD, Mansur A, Schweizer TA.

Surg Endosc. 2014 Jul;28(7):2189-98. doi: 10.1007/s00464-014-3452-7. Epub 2014 Feb 26.

PMID:
24570013
25.

Health inequity in access to bariatric surgery: a protocol for a systematic review.

Jackson TD, Zhang R, Glockler D, Pennington J, Reddigan JI, Rotstein OD, Smylie J, Perrier L, Conn LG.

Syst Rev. 2014 Feb 21;3:15. doi: 10.1186/2046-4053-3-15.

26.

Abdominal catastrophes in the intensive care unit setting.

Rezende-Neto JB, Rotstein OD.

Crit Care Clin. 2013 Oct;29(4):1017-44. doi: 10.1016/j.ccc.2013.06.005. Epub 2013 Aug 16. Review.

PMID:
24094389
27.

Comparative operative outcomes of early and delayed cholecystectomy for acute cholecystitis: a population-based propensity score analysis.

de Mestral C, Rotstein OD, Laupacis A, Hoch JS, Zagorski B, Alali AS, Nathens AB.

Ann Surg. 2014 Jan;259(1):10-5. doi: 10.1097/SLA.0b013e3182a5cf36.

PMID:
23979286
28.

Does the size of the stitch length affect surgical site infection?

McLeod RS, Brenneman FD, Rotstein OD, Bhanot P; Members of the Evidence-Based Reviews in Surgery Group.

J Am Coll Surg. 2013 Sep;217(3):556-9. doi: 10.1016/j.jamcollsurg.2013.06.004. No abstract available.

PMID:
23969115
29.

Normothermic acellular ex vivo liver perfusion reduces liver and bile duct injury of pig livers retrieved after cardiac death.

Boehnert MU, Yeung JC, Bazerbachi F, Knaak JM, Selzner N, McGilvray ID, Rotstein OD, Adeyi OA, Kandel SM, Rogalla P, Yip PM, Levy GA, Keshavjee S, Grant DR, Selzner M.

Am J Transplant. 2013 Jun;13(6):1441-9. doi: 10.1111/ajt.12224. Epub 2013 May 13.

30.

Early cholecystectomy for acute cholecystitis: a population-based retrospective cohort study of variation in practice.

de Mestral C, Laupacis A, Rotstein OD, Hoch JS, Haas B, Gomez D, Zagorski B, Nathens AB.

CMAJ Open. 2013 May 16;1(2):E62-7. doi: 10.9778/cmajo.20130001. eCollection 2013 May.

31.

Source control review in clinical trials of anti-infective agents in complicated intra-abdominal infections.

Solomkin JS, Ristagno RL, Das AF, Cone JB, Wilson SE, Rotstein OD, Murphy BS, Severin KS, Bruss JB.

Clin Infect Dis. 2013 Jun;56(12):1765-73. doi: 10.1093/cid/cit128. Epub 2013 Mar 5. Review.

PMID:
23463643
32.

Cholecystostomy: a bridge to hospital discharge but not delayed cholecystectomy.

de Mestral C, Gomez D, Haas B, Zagorski B, Rotstein OD, Nathens AB.

J Trauma Acute Care Surg. 2013 Jan;74(1):175-9; discussion 179-80. doi: 10.1097/TA.0b013e31827890e1.

PMID:
23271093
33.

A population-based analysis of the clinical course of 10,304 patients with acute cholecystitis, discharged without cholecystectomy.

de Mestral C, Rotstein OD, Laupacis A, Hoch JS, Zagorski B, Nathens AB.

J Trauma Acute Care Surg. 2013 Jan;74(1):26-30; discussion 30-1. doi: 10.1097/TA.0b013e3182788e4d.

PMID:
23271073
34.

Enhanced recovery after vascular surgery: protocol for a systematic review.

Gotlib Conn L, Rotstein OD, Greco E, Tricco AC, Perrier L, Soobiah C, Moloney T.

Syst Rev. 2012 Nov 2;1:52. doi: 10.1186/2046-4053-1-52.

35.

FGL2/fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice.

Selzner N, Liu H, Boehnert MU, Adeyi OA, Shalev I, Bartczak AM, Xue-Zhong M, Manuel J, Rotstein OD, McGilvray ID, Grant DR, Phillips MJ, Levy GA, Selzner M.

J Hepatol. 2012 Jan;56(1):153-9. doi: 10.1016/j.jhep.2011.05.033. Epub 2011 Jul 12.

PMID:
21756857
36.

Video. "No scar" small bowel resection in a survival porcine model using transcolonic NOTES(®) and transabdominal approach.

Dubcenco E, Grantcharov T, Eng FC, Streutker CJ, Baxter NN, Rotstein OD, Baker JP.

Surg Endosc. 2011 Mar;25(3):930-4. doi: 10.1007/s00464-010-1156-1. Epub 2010 Oct 7.

PMID:
20927551
37.

Altered inhibitory κBα expression in LPS-stimulated alveolar macrophages following resuscitated hemorrhagic shock.

Papia G, Fan J, Kapus A, Szaszi K, Marshall JC, Tawadros P, Ailenberg M, Rotstein OD.

Shock. 2011 Feb;35(2):171-7. doi: 10.1097/SHK.0b013e3181f21d2d.

PMID:
20661182
38.

Bone matrix proteins and extracellular acidification: potential co-regulators of osteoclast morphology.

Gramoun A, Goto T, Nordström T, Rotstein OD, Grinstein S, Heersche JN, Manolson MF.

J Cell Biochem. 2010 Oct 1;111(2):350-61. doi: 10.1002/jcb.22705.

PMID:
20506338
39.

Remote ischemic preconditioning by hindlimb occlusion prevents liver ischemic/reperfusion injury: the role of High Mobility Group-Box 1.

Wang F, Birch SE, He R, Tawadros P, Szaszi K, Kapus A, Rotstein OD.

Ann Surg. 2010 Feb;251(2):292-9. doi: 10.1097/SLA.0b013e3181bfda8c.

PMID:
19858701
40.

GEF-H1 mediates tumor necrosis factor-alpha-induced Rho activation and myosin phosphorylation: role in the regulation of tubular paracellular permeability.

Kakiashvili E, Speight P, Waheed F, Seth R, Lodyga M, Tanimura S, Kohno M, Rotstein OD, Kapus A, Szászi K.

J Biol Chem. 2009 Apr 24;284(17):11454-66. doi: 10.1074/jbc.M805933200. Epub 2009 Mar 3.

41.

Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response.

Thirone AC, Speight P, Zulys M, Rotstein OD, Szászi K, Pedersen SF, Kapus A.

Am J Physiol Cell Physiol. 2009 Mar;296(3):C463-75. doi: 10.1152/ajpcell.00467.2008. Epub 2008 Dec 24.

42.

Hypertonic saline resuscitation from hemorrhagic shock does not impair the neutrophil response to intraabdominal infection.

Papia G, Burrows LL, Sinnadurai S, Marshall JC, Tawadros PS, Kapus A, Rotstein OD.

Surgery. 2008 Nov;144(5):814-21. doi: 10.1016/j.surg.2008.07.008. Epub 2008 Sep 14.

PMID:
19081025
43.

The development of a novel intracolonic occlusion balloon for transcolonic natural orifice transluminal endoscopic surgery: description of the technique and early experience in a porcine model (with videos).

Dubcenco E, Grantcharov T, Streutker CJ, Rotstein OD, Baxter NN, Jeejeebhoy KN, Baker JP.

Gastrointest Endosc. 2008 Oct;68(4):760-6. doi: 10.1016/j.gie.2008.05.019.

PMID:
18926184
44.

A graduate student oath.

Davis KD, Seeman MV, Chapman J, Rotstein OD.

Science. 2008 Jun 20;320(5883):1587-8. doi: 10.1126/science.320.5883.1587b. No abstract available.

PMID:
18566266
45.

Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor.

Sebe A, Masszi A, Zulys M, Yeung T, Speight P, Rotstein OD, Nakano H, Mucsi I, Szászi K, Kapus A.

FEBS Lett. 2008 Jan 23;582(2):291-8. Epub 2007 Dec 27.

46.

Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8.

Jia SH, Parodo J, Kapus A, Rotstein OD, Marshall JC.

J Biol Chem. 2008 Feb 29;283(9):5402-13. Epub 2007 Dec 17.

47.

Stilbazulenyl nitrone decreases oxidative stress and reduces lung injury after hemorrhagic shock/resuscitation and LPS.

Tawadros PS, Powers KA, Yang I, Becker DA, Ginsberg MD, Szaszi K, Kapus A, Rotstein OD.

Antioxid Redox Signal. 2007 Nov;9(11):1971-7.

PMID:
17715998
48.

Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway.

Fan L, Sebe A, Péterfi Z, Masszi A, Thirone AC, Rotstein OD, Nakano H, McCulloch CA, Szászi K, Mucsi I, Kapus A.

Mol Biol Cell. 2007 Mar;18(3):1083-97. Epub 2007 Jan 10.

49.

Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages.

Powers KA, Szászi K, Khadaroo RG, Tawadros PS, Marshall JC, Kapus A, Rotstein OD.

J Exp Med. 2006 Aug 7;203(8):1951-61. Epub 2006 Jul 17.

50.

Glutathione depletion of stimulator cells inhibits responder T-cell immunogenicity in vitro and prolongs allograft survival in vivo.

McKenna GJ, Kim PT, Mui AL, Ong CJ, Rotstein OD, Warnock GL, Chung SW.

Am J Surg. 2006 May;191(5):588-92.

PMID:
16647342

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