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Items: 29


Bacteriophage Lysin CF-301, a Potent Antistaphylococcal Biofilm Agent.

Schuch R, Khan BK, Raz A, Rotolo JA, Wittekind M.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02666-16. doi: 10.1128/AAC.02666-16. Print 2017 Jul.


Targeting acid sphingomyelinase with anti-angiogenic chemotherapy.

Jacobi J, García-Barros M, Rao S, Rotolo JA, Thompson C, Mizrachi A, Feldman R, Manova K, Bielawska A, Bielawska J, Fuks Z, Kolesnick R, Haimovitz-Friedman A.

Cell Signal. 2017 Jan;29:52-61. doi: 10.1016/j.cellsig.2016.09.010. Epub 2016 Oct 1.


Correction: Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation.

Lee H, Rotolo JA, Mesicek J, Penate-Medina T, Rimner A, Liao WC, Yin X, Ragupathi G, Ehleiter D, Gulbins E, Zhai D, Reed JC, Haimovitz-Friedman A, Fuks Z, Kolesnick R.

PLoS One. 2015 Dec 30;10(12):e0146210. doi: 10.1371/journal.pone.0146210. eCollection 2015. No abstract available.


Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia.

Schuch R, Lee HM, Schneider BC, Sauve KL, Law C, Khan BK, Rotolo JA, Horiuchi Y, Couto DE, Raz A, Fischetti VA, Huang DB, Nowinski RC, Wittekind M.

J Infect Dis. 2014 May 1;209(9):1469-78. doi: 10.1093/infdis/jit637. Epub 2013 Nov 28.


Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.

Stancevic B, Varda-Bloom N, Cheng J, Fuller JD, Rotolo JA, García-Barros M, Feldman R, Rao S, Weichselbaum RR, Harats D, Haimovitz-Friedman A, Fuks Z, Sadelain M, Kolesnick R.

PLoS One. 2013 Aug 2;8(8):e69025. doi: 10.1371/journal.pone.0069025. Print 2013.


Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice.

Rotolo J, Stancevic B, Zhang J, Hua G, Fuller J, Yin X, Haimovitz-Friedman A, Kim K, Qian M, Cardó-Vila M, Fuks Z, Pasqualini R, Arap W, Kolesnick R.

J Clin Invest. 2012 May;122(5):1786-90. doi: 10.1172/JCI59920. Epub 2012 Apr 2.


Antitumor efficacy following the intracellular and interstitial release of liposomal doxorubicin.

Bandekar A, Karve S, Chang MY, Mu Q, Rotolo J, Sofou S.

Biomaterials. 2012 Jun;33(17):4345-52. doi: 10.1016/j.biomaterials.2012.02.039. Epub 2012 Mar 17.


Accelerated hematopoietic toxicity by high energy (56)Fe radiation.

Datta K, Suman S, Trani D, Doiron K, Rotolo JA, Kallakury BV, Kolesnick R, Cole MF, Fornace AJ Jr.

Int J Radiat Biol. 2012 Mar;88(3):213-22. doi: 10.3109/09553002.2012.639434. Epub 2011 Dec 12.


Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.

Lu SX, Kappel LW, Charbonneau-Allard AM, Atallah R, Holland AM, Turbide C, Hubbard VM, Rotolo JA, Smith M, Suh D, King C, Rao UK, Yim N, Bautista JL, Jenq RR, Penack O, Na IK, Liu C, Murphy G, Alpdogan O, Blumberg RS, Macian F, Holmes KV, Beauchemin N, van den Brink MR.

PLoS One. 2011;6(7):e21611. doi: 10.1371/journal.pone.0021611. Epub 2011 Jul 6.


Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation.

Lee H, Rotolo JA, Mesicek J, Penate-Medina T, Rimner A, Liao WC, Yin X, Ragupathi G, Ehleiter D, Gulbins E, Zhai D, Reed JC, Haimovitz-Friedman A, Fuks Z, Kolesnick R.

PLoS One. 2011;6(6):e19783. doi: 10.1371/journal.pone.0019783. Epub 2011 Jun 13. Erratum in: PLoS One. 2015;10(12):e0146210.


Alpha particles induce apoptosis through the sphingomyelin pathway.

Seideman JH, Stancevic B, Rotolo JA, McDevitt MR, Howell RW, Kolesnick RN, Scheinberg DA.

Radiat Res. 2011 Oct;176(4):434-46. Epub 2011 Jun 1.


Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.

Rotolo JA, Mesicek J, Maj J, Truman JP, Haimovitz-Friedman A, Kolesnick R, Fuks Z.

Cancer Res. 2010 Feb 1;70(3):957-67. doi: 10.1158/0008-5472.CAN-09-1562. Epub 2010 Jan 19.


Response: Sample size and statistical comparisons of GVHD rates in pediatric Niemann-Pick disease patients.

Kolesnick R, van den Brink M, Heller G, Rotolo JA.

Blood. 2010 Jan 14;115(2):436. doi: 10.1182/blood-2009-10-246561. No abstract available.


Cytolytic T cells induce ceramide-rich platforms in target cell membranes to initiate graft-versus-host disease.

Rotolo JA, Stancevic B, Lu SX, Zhang J, Suh D, King CG, Kappel LW, Murphy GF, Liu C, Fuks Z, van den Brink MR, Kolesnick R.

Blood. 2009 Oct 22;114(17):3693-706. doi: 10.1182/blood-2008-11-191148. Epub 2009 Aug 7.


The use of pH-triggered leaky heterogeneities on rigid lipid bilayers to improve intracellular trafficking and therapeutic potential of targeted liposomal immunochemotherapy.

Karve S, Alaouie A, Zhou Y, Rotolo J, Sofou S.

Biomaterials. 2009 Oct;30(30):6055-64. doi: 10.1016/j.biomaterials.2009.07.038. Epub 2009 Aug 7.


Timing of lethality from gastrointestinal syndrome in mice revisited.

Rotolo JA, Kolesnick R, Fuks Z.

Int J Radiat Oncol Biol Phys. 2009 Jan 1;73(1):6-8. doi: 10.1016/j.ijrobp.2008.09.009. No abstract available.


Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa.

Rotolo JA, Maj JG, Feldman R, Ren D, Haimovitz-Friedman A, Cordon-Cardo C, Cheng EH, Kolesnick R, Fuks Z.

Int J Radiat Oncol Biol Phys. 2008 Mar 1;70(3):804-15. doi: 10.1016/j.ijrobp.2007.11.043. Epub 2008 Jan 11.


Caspase-dependent and -independent activation of acid sphingomyelinase signaling.

Rotolo JA, Zhang J, Donepudi M, Lee H, Fuks Z, Kolesnick R.

J Biol Chem. 2005 Jul 15;280(28):26425-34. Epub 2005 Apr 22.


A partial allelotyping of urothelial carcinoma of bladder in the Chinese.

Zhang J, Zheng S, Gao Y, Rotolo JA, Xiao Z, Li C, Cheng S.

Carcinogenesis. 2004 Mar;25(3):343-7. Epub 2003 Nov 6.


Insulin-like growth factor-I enhances lymphoid and myeloid reconstitution after allogeneic bone marrow transplantation.

Alpdogan O, Muriglan SJ, Kappel BJ, Doubrovina E, Schmaltz C, Schiro R, Eng JM, Greenberg AS, Willis LM, Rotolo JA, O'Reilly RJ, van den Brink MR.

Transplantation. 2003 Jun 27;75(12):1977-83.


T cells require TRAIL for optimal graft-versus-tumor activity.

Schmaltz C, Alpdogan O, Kappel BJ, Muriglan SJ, Rotolo JA, Ongchin J, Willis LM, Greenberg AS, Eng JM, Crawford JM, Murphy GF, Yagita H, Walczak H, Peschon JJ, van den Brink MR.

Nat Med. 2002 Dec;8(12):1433-7. Epub 2002 Nov 11.


Donor T cell-derived TNF is required for graft-versus-host disease and graft-versus-tumor activity after bone marrow transplantation.

Schmaltz C, Alpdogan O, Muriglan SJ, Kappel BJ, Rotolo JA, Ricchetti ET, Greenberg AS, Willis LM, Murphy GF, Crawford JM, van den Brink MR.

Blood. 2003 Mar 15;101(6):2440-5. Epub 2002 Nov 7.


Administration of interleukin-7 after allogeneic bone marrow transplantation improves immune reconstitution without aggravating graft-versus-host disease.

Alpdogan O, Schmaltz C, Muriglan SJ, Kappel BJ, Perales MA, Rotolo JA, Halm JA, Rich BE, van den Brink MR.

Blood. 2001 Oct 1;98(7):2256-65.


Crohn's disease presenting with Fournier's gangrene and enterovesical fistula.

Brings HA, Matthews R, Brinkman J, Rotolo J.

Am Surg. 1997 May;63(5):401-5.


Refractory epididymitis and ejaculatory duct obstruction.

Rotolo JE.

J Urol. 1995 Nov;154(5):1863-4. No abstract available.


Penile cancer: curable with early detection.

Rotolo JE, Lynch JH.

Hosp Pract (Off Ed). 1991 Jun 15;26(6):131-8. Review.


New approaches in the treatment of renal calculi.

O'Brien WM, Rotolo JE, Pahira JJ.

Am Fam Physician. 1987 Nov;36(5):181-94. Review.


Spontaneous splenic rupture in infectious mononucleosis.

Rotolo JE.

Am J Emerg Med. 1987 Sep;5(5):383-5.


Renal cell carcinoma.

Rotolo JE, O'Brien WM, Lynch JH.

Hosp Pract (Off Ed). 1987 Feb 15;22(2):59-61, 64-7. No abstract available.


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