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Items: 1 to 50 of 369

1.

A role for the unfolded protein response stress sensor ERN1 in regulating the response to MEK inhibitors in KRAS mutant colon cancers.

Šuštić T, van Wageningen S, Bosdriesz E, Reid RJD, Dittmar J, Lieftink C, Beijersbergen RL, Wessels LFA, Rothstein R, Bernards R.

Genome Med. 2018 Nov 27;10(1):90. doi: 10.1186/s13073-018-0600-z.

2.

Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability.

Oh J, Lee SJ, Rothstein R, Symington LS.

Cell Rep. 2018 Nov 13;25(7):1681-1692.e4. doi: 10.1016/j.celrep.2018.10.030.

3.

Increased chromosomal mobility after DNA damage is controlled by interactions between the recombination machinery and the checkpoint.

Smith MJ, Bryant EE, Rothstein R.

Genes Dev. 2018 Sep 1;32(17-18):1242-1251. doi: 10.1101/gad.317966.118.

PMID:
30181361
4.

Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma.

Ronsley R, Rassekh SR, Shen Y, Lee AF, Jantzen C, Halparin J, Albert C, Hawkins DS, Amed S, Rothstein R, Mungall AJ, Dix D, Blair G, Nadel H, Jones SJM, Laskin J, Marra MA, J Deyell R.

Cold Spring Harb Mol Case Stud. 2018 Apr 2;4(2). pii: a002568. doi: 10.1101/mcs.a002568. Print 2018 Apr.

5.

ASGE EndoVators Summit: Defining the role and value of endoscopic therapies in obesity management.

ASGE EndoVators Task Force, Ryou M, McQuaid KR, Thompson CC, Edmundowicz S, Mergener K, Abu Dayyeh B, Apovian C, Burke C, Chand B, Chandraker A, Deas T, Dietz W, Dunkin B, Ernest O, Faigel D, Garber S, Hamdy O, Kaplan L, Kumar N, Kushner R, Larsen MC, Lerner H, Littenberg G, Mantzoros C, Mattar S, Moore R, Rinella M, Rothstein R, Schillinger D, Spring B, Sullivan S, Tice J, Vargo J, Wilson E, Woods K, Zundel N.

Gastrointest Endosc. 2017 Nov;86(5):757-767. doi: 10.1016/j.gie.2017.08.004. Epub 2017 Oct 12. No abstract available.

PMID:
29031371
6.

ASGE EndoVators Summit: Defining the role and value of endoscopic therapies in obesity management.

Ryou M, McQuaid KR, Thompson CC, Edmundowicz S, Mergener K, Dayyeh BA, Apovian C, Burke C, Chand B, Chandraker A, Deas T, Dietz W, Dunkin B, Ernest O, Faigel D, Garber S, Hamdy O, Kaplan L, Kumar N, Kushner R, Larsen MC, Lerner H, Littenberg G, Mantzoros C, Mattar S, Moore R, Rinella M, Rothstein R, Schillinger D, Spring B, Sullivan S, Tice J, Vargo J, Wilson E, Woods K, Zundel N.

Surg Obes Relat Dis. 2017 Nov;13(11):1805-1816. doi: 10.1016/j.soard.2017.08.024. Epub 2017 Sep 8. No abstract available.

PMID:
29030161
7.

The Consensus from the Mycobacterium avium ssp. paratuberculosis (MAP) Conference 2017.

Kuenstner JT, Naser S, Chamberlin W, Borody T, Graham DY, McNees A, Hermon-Taylor J, Hermon-Taylor A, Dow CT, Thayer W, Biesecker J, Collins MT, Sechi LA, Singh SV, Zhang P, Shafran I, Weg S, Telega G, Rothstein R, Oken H, Schimpff S, Bach H, Bull T, Grant I, Ellingson J, Dahmen H, Lipton J, Gupta S, Chaubey K, Singh M, Agarwal P, Kumar A, Misri J, Sohal J, Dhama K, Hemati Z, Davis W, Hier M, Aitken J, Pierce E, Parrish N, Goldberg N, Kali M, Bendre S, Agrawal G, Baldassano R, Linn P, Sweeney RW, Fecteau M, Hofstaedter C, Potula R, Timofeeva O, Geier S, John K, Zayanni N, Malaty HM, Kahlenborn C, Kravitz A, Bulfon A, Daskalopoulos G, Mitchell H, Neilan B, Timms V, Cossu D, Mameli G, Angermeier P, Jelic T, Goethe R, Juste RA, Kuenstner L.

Front Public Health. 2017 Sep 27;5:208. doi: 10.3389/fpubh.2017.00208. eCollection 2017.

8.

CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.

Billon P, Bryant EE, Joseph SA, Nambiar TS, Hayward SB, Rothstein R, Ciccia A.

Mol Cell. 2017 Sep 21;67(6):1068-1079.e4. doi: 10.1016/j.molcel.2017.08.008. Epub 2017 Sep 7.

9.

Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage.

Miné-Hattab J, Recamier V, Izeddin I, Rothstein R, Darzacq X.

Mol Biol Cell. 2017 Aug 9. pii: mbc.E17-05-0317. doi: 10.1091/mbc.E17-05-0317. [Epub ahead of print]

10.

Radiofrequency ablation for the treatment of weight regain after Roux-en-Y gastric bypass surgery.

Abrams JA, Komanduri S, Shaheen NJ, Wang Z, Rothstein RI.

Gastrointest Endosc. 2018 Jan;87(1):275-279.e2. doi: 10.1016/j.gie.2017.06.030. Epub 2017 Jul 13.

PMID:
28713063
11.

Subsquamous intestinal metaplasia is common in treatment-naïve Barrett's esophagus.

Bartel MJ, Srivastava A, Gordon S, Rothstein RI, Pohl H.

Gastrointest Endosc. 2018 Jan;87(1):67-74. doi: 10.1016/j.gie.2017.06.024. Epub 2017 Jul 4.

PMID:
28687439
12.

Poetry in motion: Increased chromosomal mobility after DNA damage.

Smith MJ, Rothstein R.

DNA Repair (Amst). 2017 Aug;56:102-108. doi: 10.1016/j.dnarep.2017.06.012. Epub 2017 Jun 9. Review.

13.

Bariatric and Metabolic Endoscopy.

Rothstein RI.

Gastrointest Endosc Clin N Am. 2017 Apr;27(2):xv-xvi. doi: 10.1016/j.giec.2017.01.006. No abstract available.

PMID:
28292413
14.

Selected Endoscopic Gastric Devices for Obesity.

Sampath K, Rothstein RI.

Gastrointest Endosc Clin N Am. 2017 Apr;27(2):267-275. doi: 10.1016/j.giec.2017.01.005. Review.

PMID:
28292405
15.

Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies.

Rios-Doria J, Harper J, Rothstein R, Wetzel L, Chesebrough J, Marrero A, Chen C, Strout P, Mulgrew K, McGlinchey K, Fleming R, Bezabeh B, Meekin J, Stewart D, Kennedy M, Martin P, Buchanan A, Dimasi N, Michelotti E, Hollingsworth R.

Cancer Res. 2017 May 15;77(10):2686-2698. doi: 10.1158/0008-5472.CAN-16-2854. Epub 2017 Mar 10.

16.

Chemoprevention of colorectal cancer in inflammatory bowel disease.

Ehrlich AC, Patel S, Meillier A, Rothstein RD, Friedenberg FK.

Expert Rev Anticancer Ther. 2017 Mar;17(3):247-255. doi: 10.1080/14737140.2017.1283987. Epub 2017 Feb 1. Review.

PMID:
28095263
17.

Targeting CD73 in the tumor microenvironment with MEDI9447.

Hay CM, Sult E, Huang Q, Mulgrew K, Fuhrmann SR, McGlinchey KA, Hammond SA, Rothstein R, Rios-Doria J, Poon E, Holoweckyj N, Durham NM, Leow CC, Diedrich G, Damschroder M, Herbst R, Hollingsworth RE, Sachsenmeier KF.

Oncoimmunology. 2016 Jul 11;5(8):e1208875. doi: 10.1080/2162402X.2016.1208875. eCollection 2016 Aug.

18.

A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells.

Reid RJ, Du X, Sunjevaric I, Rayannavar V, Dittmar J, Bryant E, Maurer M, Rothstein R.

Genetics. 2016 Oct;204(2):807-819. Epub 2016 Aug 24.

19.

Lymphocytic Esophagitis in Nonachalasia Primary Esophageal Motility Disorders: Improved Criteria, Prevalence, Strength of Association, and Natural History.

Putra J, Muller KE, Hussain ZH, Parker S, Gabbard S, Brickley EB, Lacy BE, Rothstein R, Lisovsky M.

Am J Surg Pathol. 2016 Dec;40(12):1679-1685.

20.

Hydrothermal duodenal mucosal resurfacing: a novel procedural therapy for metabolic disease.

Galvao Neto M, Rodriguez L, Becerra P, Mani S, Rothstein R.

VideoGIE. 2016 Aug 11;1(1):10-11. doi: 10.1016/j.vgie.2016.07.011. eCollection 2016 Sep. No abstract available.

21.

Measurement of Fractional Exhaled Nitric Oxide as a Marker of Disease Activity in Inflammatory Bowel Disease.

Ikonomi E, Rothstein RD, Ehrlich AC, Friedenberg FK.

J Gastroenterol Pancreatol Liver Disord. 2016;3(1). doi: 10.15226/2374-815X/3/1/00146. Epub 2016 Jan 27.

22.

Quality of optical diagnosis of diminutive polyps and associated factors.

Pohl H, Bensen SP, Toor A, Gordon SR, Levy LC, Anderson PB, Anderson JC, Rothstein RI, Robertson DJ.

Endoscopy. 2016 Sep;48(9):817-22. doi: 10.1055/s-0042-108432. Epub 2016 Jun 8.

PMID:
27275860
23.

Endoscopic Devices for Obesity.

Sampath K, Dinani AM, Rothstein RI.

Curr Obes Rep. 2016 Jun;5(2):251-61. doi: 10.1007/s13679-016-0217-8. Review.

PMID:
27115879
24.

Recombination-Mediated Telomere Maintenance in Saccharomyces cerevisiae Is Not Dependent on the Shu Complex.

van Mourik PM, de Jong J, Agpalo D, Claussin C, Rothstein R, Chang M.

PLoS One. 2016 Mar 14;11(3):e0151314. doi: 10.1371/journal.pone.0151314. eCollection 2016.

25.

A Potent HER3 Monoclonal Antibody That Blocks Both Ligand-Dependent and -Independent Activities: Differential Impacts of PTEN Status on Tumor Response.

Xiao Z, Carrasco RA, Schifferli K, Kinneer K, Tammali R, Chen H, Rothstein R, Wetzel L, Yang C, Chowdhury P, Tsui P, Steiner P, Jallal B, Herbst R, Hollingsworth RE, Tice DA.

Mol Cancer Ther. 2016 Apr;15(4):689-701. doi: 10.1158/1535-7163.MCT-15-0555. Epub 2016 Feb 15.

26.

Drug eluting biliary stents to decrease stent failure rates: A review of the literature.

Shatzel J, Kim J, Sampath K, Syed S, Saad J, Hussain ZH, Mody K, Pipas JM, Gordon S, Gardner T, Rothstein RI.

World J Gastrointest Endosc. 2016 Jan 25;8(2):77-85. doi: 10.4253/wjge.v8.i2.77. Review.

27.

Predictors Of Treatment Failure After Radiofrequency Ablation For Intramucosal Adenocarcinoma in Barrett Esophagus: A Multi-institutional Retrospective Cohort Study.

Agoston AT, Strauss AC, Dulai PS, Hagen CE, Muzikansky A, Fudman DI, Abrams JA, Forcione DG, Jajoo K, Saltzman JR, Odze RD, Lauwers GY, Gordon SR, Lightdale CJ, Rothstein RI, Srivastava A.

Am J Surg Pathol. 2016 Apr;40(4):554-62. doi: 10.1097/PAS.0000000000000566.

PMID:
26645729
28.

A Trial of Calcium and Vitamin D for the Prevention of Colorectal Adenomas.

Baron JA, Barry EL, Mott LA, Rees JR, Sandler RS, Snover DC, Bostick RM, Ivanova A, Cole BF, Ahnen DJ, Beck GJ, Bresalier RS, Burke CA, Church TR, Cruz-Correa M, Figueiredo JC, Goodman M, Kim AS, Robertson DJ, Rothstein R, Shaukat A, Seabrook ME, Summers RW.

N Engl J Med. 2015 Oct 15;373(16):1519-30. doi: 10.1056/NEJMoa1500409.

29.

Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.

Rios-Doria J, Durham N, Wetzel L, Rothstein R, Chesebrough J, Holoweckyj N, Zhao W, Leow CC, Hollingsworth R.

Neoplasia. 2015 Aug;17(8):661-70. doi: 10.1016/j.neo.2015.08.004.

30.

Lymphocytic Esophagitis With CD4 T-cell-predominant Intraepithelial Lymphocytes and Primary Esophageal Motility Abnormalities: A Potential Novel Clinicopathologic Entity.

Xue Y, Suriawinata A, Liu X, Li Z, Gabbard S, Rothstein R, Lacy B, Lisovsky M.

Am J Surg Pathol. 2015 Nov;39(11):1558-67. doi: 10.1097/PAS.0000000000000493.

PMID:
26379147
31.

Incidence of Esophageal Adenocarcinoma and Causes of Mortality After Radiofrequency Ablation of Barrett's Esophagus.

Wolf WA, Pasricha S, Cotton C, Li N, Triadafilopoulos G, Muthusamy VR, Chmielewski GW, Corbett FS, Camara DS, Lightdale CJ, Wolfsen H, Chang KJ, Overholt BF, Pruitt RE, Ertan A, Komanduri S, Infantolino A, Rothstein RI, Shaheen NJ.

Gastroenterology. 2015 Dec;149(7):1752-1761.e1. doi: 10.1053/j.gastro.2015.08.048. Epub 2015 Aug 29.

32.

Multifocal Synchronous Granular Cell Tumors of the Gastrointestinal Tract.

Lipkin-Moore Z, Thomas RM, Rothstein RD.

ACG Case Rep J. 2014 Jul 8;1(4):193-5. doi: 10.14309/crj.2014.49. eCollection 2014 Jul.

33.

Cap-assisted colonoscopy and detection of Adenomatous Polyps (CAP) study: a randomized trial.

Pohl H, Bensen SP, Toor A, Gordon SR, Levy LC, Berk B, Anderson PB, Anderson JC, Rothstein RI, MacKenzie TA, Robertson DJ.

Endoscopy. 2015 Oct;47(10):891-7. doi: 10.1055/s-0034-1392261. Epub 2015 Jun 30.

PMID:
26126162
34.

A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways.

Rios-Doria J, Sabol D, Chesebrough J, Stewart D, Xu L, Tammali R, Cheng L, Du Q, Schifferli K, Rothstein R, Leow CC, Heidbrink-Thompson J, Jin X, Gao C, Friedman J, Wilkinson B, Damschroder M, Pierce AJ, Hollingsworth RE, Tice DA, Michelotti EF.

Mol Cancer Ther. 2015 Jul;14(7):1637-49. doi: 10.1158/1535-7163.MCT-14-1040. Epub 2015 May 6.

35.

Sex and race and/or ethnicity differences in patients undergoing radiofrequency ablation for Barrett's esophagus: results from the U.S. RFA Registry.

Pasricha S, Li N, Bulsiewicz WJ, Rothstein RI, Infantolino A, Ertan A, Camara DS, Dellon ES, Triadafilopoulos G, Lightdale CJ, Madanick RD, Lyday WD, Muthusamy RV, Overholt BF, Shaheen NJ.

Gastrointest Endosc. 2015 Aug;82(2):276-84. doi: 10.1016/j.gie.2015.01.015. Epub 2015 Apr 1.

36.

Cell biology of mitotic recombination.

Lisby M, Rothstein R.

Cold Spring Harb Perspect Biol. 2015 Mar 2;7(3):a016535. doi: 10.1101/cshperspect.a016535. Review.

37.

Mechanisms and regulation of mitotic recombination in Saccharomyces cerevisiae.

Symington LS, Rothstein R, Lisby M.

Genetics. 2014 Nov;198(3):795-835. doi: 10.1534/genetics.114.166140. Review.

38.

Radiofrequency ablation for Barrett's-associated intramucosal carcinoma: a multi-center follow-up study.

Strauss AC, Agoston AT, Dulai PS, Srivastava A, Rothstein RI.

Surg Endosc. 2014 Dec;28(12):3366-72. doi: 10.1007/s00464-014-3629-0.

PMID:
24950726
39.

Durability and predictors of successful radiofrequency ablation for Barrett's esophagus.

Pasricha S, Bulsiewicz WJ, Hathorn KE, Komanduri S, Muthusamy VR, Rothstein RI, Wolfsen HC, Lightdale CJ, Overholt BF, Camara DS, Dellon ES, Lyday WD, Ertan A, Chmielewski GW, Shaheen NJ.

Clin Gastroenterol Hepatol. 2014 Nov;12(11):1840-7.e1. doi: 10.1016/j.cgh.2014.04.034. Epub 2014 May 9.

40.

Transoral mucosal excision sutured gastroplasty: a pilot study for GERD and obesity with two-year follow-up.

Legner A, Altorjay A, Juhasz A, Stadlhuber R, Reich V, Hunt B, Rothstein R, Filipi C.

Surg Innov. 2014 Oct;21(5):456-63. doi: 10.1177/1553350613508228. Epub 2014 Mar 12.

41.

Transplantation of mucosa from stomach to esophagus to prevent stricture after circumferential endoscopic submucosal dissection of early squamous cell.

Hochberger J, Koehler P, Wedi E, Gluer S, Rothstein RI, Niemann H, Hilfiker A, Gonzalez S, Kruse E.

Gastroenterology. 2014 Apr;146(4):906-9. doi: 10.1053/j.gastro.2014.01.063. Epub 2014 Feb 8. No abstract available.

PMID:
24512802
42.

The PCNA interaction protein box sequence in Rad54 is an integral part of its ATPase domain and is required for efficient DNA repair and recombination.

Burgess RC, Sebesta M, Sisakova A, Marini VP, Lisby M, Damborsky J, Klein H, Rothstein R, Krejci L.

PLoS One. 2013 Dec 20;8(12):e82630. doi: 10.1371/journal.pone.0082630. eCollection 2013. Erratum in: PLoS One. 2014;9(6):e101095.

43.

Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme.

Fu Q, Chow J, Bernstein KA, Makharashvili N, Arora S, Lee CF, Person MD, Rothstein R, Paull TT.

Mol Cell Biol. 2014 Mar;34(5):778-93. doi: 10.1128/MCB.00963-13. Epub 2013 Dec 16. Erratum in: Mol Cell Biol. 2014 Nov 15;34(22):4213.

44.

Repair of strand breaks by homologous recombination.

Jasin M, Rothstein R.

Cold Spring Harb Perspect Biol. 2013 Nov 1;5(11):a012740. doi: 10.1101/cshperspect.a012740. Review.

45.

Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.

Bernstein KA, Mimitou EP, Mihalevic MJ, Chen H, Sunjaveric I, Symington LS, Rothstein R.

Genetics. 2013 Dec;195(4):1241-51. doi: 10.1534/genetics.113.157370. Epub 2013 Oct 4.

46.

Linaclotide: a novel compound for the treatment of irritable bowel syndrome with constipation.

Rothstein RD, Friedenberg FK.

Expert Opin Pharmacother. 2013 Oct;14(15):2125-32. doi: 10.1517/14656566.2013.833605. Epub 2013 Sep 5. Review.

PMID:
24007408
47.

DNA in motion during double-strand break repair.

Miné-Hattab J, Rothstein R.

Trends Cell Biol. 2013 Nov;23(11):529-36. doi: 10.1016/j.tcb.2013.05.006. Epub 2013 Jul 15. Review.

48.

Response.

Dulai PS, Gordon SR, Rothstein RI.

Gastrointest Endosc. 2013 Jul;78(1):191. doi: 10.1016/j.gie.2013.02.025. No abstract available.

PMID:
23820416
49.

The Shu complex regulates Rad52 localization during rDNA repair.

Bernstein KA, Juanchich A, Sunjevaric I, Rothstein R.

DNA Repair (Amst). 2013 Sep;12(9):786-90. doi: 10.1016/j.dnarep.2013.05.003. Epub 2013 Jun 19.

50.

Transgastric-assisted endoscopic fundoplication.

Spaniolas K, Rothstein RI, Trus TL.

Case Rep Med. 2013;2013:280628. doi: 10.1155/2013/280628. Epub 2013 May 13.

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