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Items: 1 to 50 of 263

1.

"The doctor said formula would help me": Health sector influences on use of infant formula in peri-urban Lima, Peru.

Rothstein JD, Caulfield LE, Broaddus-Shea ET, Muschelli J, Gilman RH, Winch PJ.

Soc Sci Med. 2019 Jun 7. pii: S0277-9536(19)30293-X. doi: 10.1016/j.socscimed.2019.05.029. [Epub ahead of print] No abstract available.

PMID:
31189492
2.

Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin.

Miller SJ, Philips T, Kim N, Dastgheyb R, Chen Z, Hsieh YC, Daigle JG, Datta M, Chew J, Vidensky S, Pham JT, Hughes EG, Robinson MB, Sattler R, Tomer R, Suk JS, Bergles DE, Haughey N, Pletnikov M, Hanes J, Rothstein JD.

Nat Neurosci. 2019 May;22(5):741-752. doi: 10.1038/s41593-019-0366-7. Epub 2019 Apr 1.

PMID:
30936556
3.

Household Contamination of Baby Bottles and Opportunities to Improve Bottle Hygiene in Peri-Urban Lima, Peru.

Rothstein JD, Mendoza AL, Cabrera LZ, Pachas J, Calderón M, Pajuelo MJ, Caulfield LE, Winch PJ, Gilman RH.

Am J Trop Med Hyg. 2019 Apr;100(4):988-997. doi: 10.4269/ajtmh.18-0301.

PMID:
30834885
4.

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.

Chew J, Cook C, Gendron TF, Jansen-West K, Del Rosso G, Daughrity LM, Castanedes-Casey M, Kurti A, Stankowski JN, Disney MD, Rothstein JD, Dickson DW, Fryer JD, Zhang YJ, Petrucelli L.

Mol Neurodegener. 2019 Feb 15;14(1):9. doi: 10.1186/s13024-019-0310-z.

5.

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.

Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT.

Neuron. 2019 Jan 16;101(2):349. doi: 10.1016/j.neuron.2018.12.031. No abstract available.

6.

Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model.

Miller SJ, Glatzer JC, Hsieh YC, Rothstein JD.

J Neurogenet. 2018 Dec;32(4):322-335. doi: 10.1080/01677063.2018.1513508. Epub 2018 Nov 6.

PMID:
30398075
7.

Food purchase patterns indicative of household food access insecurity, children's dietary diversity and intake, and nutritional status using a newly developed and validated tool in the Peruvian Amazon.

Ambikapathi R, Rothstein JD, Yori PP, Olortegui MP, Lee G, Kosek MN, Caulfield LE.

Food Secur. 2018;10(4):999-1011. doi: 10.1007/s12571-018-0815-2. Epub 2018 Jun 26.

8.

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease.

Eftekharzadeh B, Daigle JG, Kapinos LE, Coyne A, Schiantarelli J, Carlomagno Y, Cook C, Miller SJ, Dujardin S, Amaral AS, Grima JC, Bennett RE, Tepper K, DeTure M, Vanderburg CR, Corjuc BT, DeVos SL, Gonzalez JA, Chew J, Vidensky S, Gage FH, Mertens J, Troncoso J, Mandelkow E, Salvatella X, Lim RYH, Petrucelli L, Wegmann S, Rothstein JD, Hyman BT.

Neuron. 2018 Sep 5;99(5):925-940.e7. doi: 10.1016/j.neuron.2018.07.039. Erratum in: Neuron. 2019 Jan 16;101(2):349.

PMID:
30189209
9.

Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis.

Hoye ML, Regan MR, Jensen LA, Lake AM, Reddy LV, Vidensky S, Richard JP, Maragakis NJ, Rothstein JD, Dougherty JD, Miller TM.

Brain. 2018 Sep 1;141(9):2561-2575. doi: 10.1093/brain/awy182.

PMID:
30007309
10.

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells.

Perkins EM, Clarkson YL, Suminaite D, Lyndon AR, Tanaka K, Rothstein JD, Skehel P, Wyllie DJA, Jackson M.

Hum Mol Genet. 2018 May 8. doi: 10.1093/hmg/ddy169. [Epub ahead of print]

11.

Stress Granule Assembly Disrupts Nucleocytoplasmic Transport.

Zhang K, Daigle JG, Cunningham KM, Coyne AN, Ruan K, Grima JC, Bowen KE, Wadhwa H, Yang P, Rigo F, Taylor JP, Gitler AD, Rothstein JD, Lloyd TE.

Cell. 2018 May 3;173(4):958-971.e17. doi: 10.1016/j.cell.2018.03.025. Epub 2018 Apr 5.

12.

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Shankaracharya, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A; ITALSGEN Consortium, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L; Genomic Translation for ALS Care (GTAC) Consortium, Moreno CAM, Kamalakaran S, Goldstein DB; ALS Sequencing Consortium, Gitler AD, Harris T, Myers RM; NYGC ALS Consortium, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC; Answer ALS Foundation, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E; Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J; SLAGEN Consortium, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C; French ALS Consortium, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A; Project MinE ALS Sequencing Consortium, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH Jr, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chiò A, Shaw CE, Traynor BJ, Landers JE.

Neuron. 2018 Mar 21;97(6):1268-1283.e6. doi: 10.1016/j.neuron.2018.02.027.

13.

Edaravone: A new drug approved for ALS.

Rothstein JD.

Cell. 2017 Nov 2;171(4):725. doi: 10.1016/j.cell.2017.10.011.

14.

Oligodendroglia: metabolic supporters of neurons.

Philips T, Rothstein JD.

J Clin Invest. 2017 Sep 1;127(9):3271-3280. doi: 10.1172/JCI90610. Epub 2017 Sep 1. Review.

15.

3D Printer Generated Tissue iMolds for Cleared Tissue Using Single- and Multi-Photon Microscopy for Deep Tissue Evaluation.

Miller SJ, Rothstein JD.

Biol Proced Online. 2017 Jul 5;19:7. doi: 10.1186/s12575-017-0057-2. eCollection 2017.

16.

Neurodegenerative disease: Two-for-one on potential therapies.

Zhang K, Rothstein JD.

Nature. 2017 Apr 20;544(7650):302-303. doi: 10.1038/nature21911. Epub 2017 Apr 12. No abstract available.

PMID:
28405020
17.

Mutant Huntingtin Disrupts the Nuclear Pore Complex.

Grima JC, Daigle JG, Arbez N, Cunningham KC, Zhang K, Ochaba J, Geater C, Morozko E, Stocksdale J, Glatzer JC, Pham JT, Ahmed I, Peng Q, Wadhwa H, Pletnikova O, Troncoso JC, Duan W, Snyder SH, Ranum LPW, Thompson LM, Lloyd TE, Ross CA, Rothstein JD.

Neuron. 2017 Apr 5;94(1):93-107.e6. doi: 10.1016/j.neuron.2017.03.023.

18.

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis.

Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, Tabassian LJ, Lee CW, Yue M, Tong J, Song Y, Castanedes-Casey M, Rousseau L, Phillips V, Dickson DW, Rademakers R, Fryer JD, Rush BK, Pedraza O, Caputo AM, Desaro P, Palmucci C, Robertson A, Heckman MG, Diehl NN, Wiggs E, Tierney M, Braun L, Farren J, Lacomis D, Ladha S, Fournier CN, McCluskey LF, Elman LB, Toledo JB, McBride JD, Tiloca C, Morelli C, Poletti B, Solca F, Prelle A, Wuu J, Jockel-Balsarotti J, Rigo F, Ambrose C, Datta A, Yang W, Raitcheva D, Antognetti G, McCampbell A, Van Swieten JC, Miller BL, Boxer AL, Brown RH, Bowser R, Miller TM, Trojanowski JQ, Grossman M, Berry JD, Hu WT, Ratti A, Traynor BJ, Disney MD, Benatar M, Silani V, Glass JD, Floeter MK, Rothstein JD, Boylan KB, Petrucelli L.

Sci Transl Med. 2017 Mar 29;9(383). pii: eaai7866. doi: 10.1126/scitranslmed.aai7866.

19.

Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST.

Perkins EM, Suminaite D, Clarkson YL, Lee SK, Lyndon AR, Rothstein JD, Wyllie DJ, Tanaka K, Jackson M.

Hum Mol Genet. 2016 Oct 15;25(20):4448-4461. doi: 10.1093/hmg/ddw274.

20.

c9orf72 Disease-Related Foci Are Each Composed of One Mutant Expanded Repeat RNA.

Liu J, Hu J, Ludlow AT, Pham JT, Shay JW, Rothstein JD, Corey DR.

Cell Chem Biol. 2017 Feb 16;24(2):141-148. doi: 10.1016/j.chembiol.2016.12.018. Epub 2017 Jan 26.

21.

Qualitative Assessment of the Feasibility, Usability, and Acceptability of a Mobile Client Data App for Community-Based Maternal, Neonatal, and Child Care in Rural Ghana.

Rothstein JD, Jennings L, Moorthy A, Yang F, Gee L, Romano K, Hutchful D, Labrique AB, LeFevre AE.

Int J Telemed Appl. 2016;2016:2515420. doi: 10.1155/2016/2515420. Epub 2016 Dec 14.

22.

Astroglial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model.

Miller SJ, Zhang PW, Glatzer J, Rothstein JD.

J Neurogenet. 2017 Mar - Jun;31(1-2):37-48. doi: 10.1080/01677063.2016.1260128. Epub 2016 Dec 25.

PMID:
28019127
23.

Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.

Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, Wong PC, Monteiro MJ.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7580-E7589. Epub 2016 Nov 9.

24.

The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons.

Ehmsen JT, Liu Y, Wang Y, Paladugu N, Johnson AE, Rothstein JD, du Lac S, Mattson MP, Höke A.

Sci Rep. 2016 Oct 19;6:35592. doi: 10.1038/srep35592.

25.

Astroglia in Thick Tissue with Super Resolution and Cellular Reconstruction.

Miller SJ, Rothstein JD.

PLoS One. 2016 Aug 5;11(8):e0160391. doi: 10.1371/journal.pone.0160391. eCollection 2016.

26.

C9ORF72-ALS/FTD: Transgenic Mice Make a Come-BAC.

Hayes LR, Rothstein JD.

Neuron. 2016 May 4;90(3):427-31. doi: 10.1016/j.neuron.2016.04.026. Review.

27.

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease.

Haeusler AR, Donnelly CJ, Rothstein JD.

Nat Rev Neurosci. 2016 Jun;17(6):383-95. doi: 10.1038/nrn.2016.38. Epub 2016 May 6. Review.

PMID:
27150398
28.

Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD.

Zhang K, Grima JC, Rothstein JD, Lloyd TE.

Nucleus. 2016 Apr 25;7(2):132-7. doi: 10.1080/19491034.2016.1172152. Epub 2016 Apr 26. Review.

29.

C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins.

Zhang YJ, Gendron TF, Grima JC, Sasaguri H, Jansen-West K, Xu YF, Katzman RB, Gass J, Murray ME, Shinohara M, Lin WL, Garrett A, Stankowski JN, Daughrity L, Tong J, Perkerson EA, Yue M, Chew J, Castanedes-Casey M, Kurti A, Wang ZS, Liesinger AM, Baker JD, Jiang J, Lagier-Tourenne C, Edbauer D, Cleveland DW, Rademakers R, Boylan KB, Bu G, Link CD, Dickey CA, Rothstein JD, Dickson DW, Fryer JD, Petrucelli L.

Nat Neurosci. 2016 May;19(5):668-677. doi: 10.1038/nn.4272. Epub 2016 Mar 21.

30.

Stereotyped spatial patterns of functional synaptic connectivity in the cerebellar cortex.

Valera AM, Binda F, Pawlowski SA, Dupont JL, Casella JF, Rothstein JD, Poulain B, Isope P.

Elife. 2016 Mar 16;5. pii: e09862. doi: 10.7554/eLife.09862.

31.

The transcription factor Pax6 contributes to the induction of GLT-1 expression in astrocytes through an interaction with a distal enhancer element.

Ghosh M, Lane M, Krizman E, Sattler R, Rothstein JD, Robinson MB.

J Neurochem. 2016 Jan;136(2):262-75. doi: 10.1111/jnc.13406. Epub 2015 Nov 24.

32.

Rodent Models of Amyotrophic Lateral Sclerosis.

Philips T, Rothstein JD.

Curr Protoc Pharmacol. 2015 Jun 1;69:5.67.1-21. doi: 10.1002/0471141755.ph0567s69. Review.

33.

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.

Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, Daley EL, Miller SJ, Cunningham KM, Vidensky S, Gupta S, Thomas MA, Hong I, Chiu SL, Huganir RL, Ostrow LW, Matunis MJ, Wang J, Sattler R, Lloyd TE, Rothstein JD.

Nature. 2015 Sep 3;525(7567):56-61. doi: 10.1038/nature14973. Epub 2015 Aug 26.

34.

Process Evaluation of a Comprehensive Supermarket Intervention in a Low-Income Baltimore Community.

Lee RM, Rothstein JD, Gergen J, Zachary DA, Smith JC, Palmer AM, Gittelsohn J, Surkan PJ.

Health Promot Pract. 2015 Nov;16(6):849-58. doi: 10.1177/1524839915599359. Epub 2015 Aug 21.

PMID:
26296352
35.

Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast-derived iPS cells using zinc-finger nuclease technology.

Zhang PW, Haidet-Phillips AM, Pham JT, Lee Y, Huo Y, Tienari PJ, Maragakis NJ, Sattler R, Rothstein JD.

Glia. 2016 Jan;64(1):63-75. doi: 10.1002/glia.22903. Epub 2015 Aug 21.

36.

Determinants of Caregivers' Use and Adoption of Household Water Chlorination: A Qualitative Study with Peri-Urban Communities in the Peruvian Amazon.

Rothstein JD, Leontsini E, Olortegui MP, Yori PP, Surkan PJ, Kosek M.

Am J Trop Med Hyg. 2015 Sep;93(3):626-635. doi: 10.4269/ajtmh.14-0654. Epub 2015 Jul 14.

37.

A comprehensive library of familial human amyotrophic lateral sclerosis induced pluripotent stem cells.

Li Y, Balasubramanian U, Cohen D, Zhang PW, Mosmiller E, Sattler R, Maragakis NJ, Rothstein JD.

PLoS One. 2015 Mar 11;10(3):e0118266. doi: 10.1371/journal.pone.0118266. eCollection 2015.

38.

Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study.

Al-Sarraj S, King A, Cleveland M, Pradat PF, Corse A, Rothstein JD, Leigh PN, Abila B, Bates S, Wurthner J, Meininger V.

Acta Neuropathol Commun. 2014 Dec 14;2:165. doi: 10.1186/s40478-014-0165-z.

39.

Deficiency in monocarboxylate transporter 1 (MCT1) in mice delays regeneration of peripheral nerves following sciatic nerve crush.

Morrison BM, Tsingalia A, Vidensky S, Lee Y, Jin L, Farah MH, Lengacher S, Magistretti PJ, Pellerin L, Rothstein JD.

Exp Neurol. 2015 Jan;263:325-38. doi: 10.1016/j.expneurol.2014.10.018. Epub 2014 Oct 29.

40.

Transplanted glial restricted precursor cells improve neurobehavioral and neuropathological outcomes in a mouse model of neonatal white matter injury despite limited cell survival.

Porambo M, Phillips AW, Marx J, Ternes K, Arauz E, Pletnikov M, Wilson MA, Rothstein JD, Johnston MV, Fatemi A.

Glia. 2015 Mar;63(3):452-65. doi: 10.1002/glia.22764. Epub 2014 Nov 6.

41.

Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial.

Cudkowicz ME, Titus S, Kearney M, Yu H, Sherman A, Schoenfeld D, Hayden D, Shui A, Brooks B, Conwit R, Felsenstein D, Greenblatt DJ, Keroack M, Kissel JT, Miller R, Rosenfeld J, Rothstein JD, Simpson E, Tolkoff-Rubin N, Zinman L, Shefner JM; Ceftriaxone Study Investigators.

Lancet Neurol. 2014 Nov;13(11):1083-1091. doi: 10.1016/S1474-4422(14)70222-4. Epub 2014 Oct 5.

42.

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS.

Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, Cudkowicz ME, Boeve BF, Dickson D, Floeter MK, Traynor BJ, Morelli C, Ratti A, Silani V, Rademakers R, Brown RH, Rothstein JD, Boylan KB, Petrucelli L, Disney MD.

Neuron. 2014 Oct 1;84(1):239. doi: 10.1016/j.neuron.2014.09.019. Epub 2014 Oct 1. No abstract available.

43.

Preclinical models: needed in translation? A Pro/Con debate.

Philips T, Rothstein JD, Pouladi MA.

Mov Disord. 2014 Sep 15;29(11):1391-6. doi: 10.1002/mds.26010. Review.

PMID:
25216370
44.

Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.

Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, Cudkowicz ME, Boeve BF, Dickson D, Floeter MK, Traynor BJ, Morelli C, Ratti A, Silani V, Rademakers R, Brown RH, Rothstein JD, Boylan KB, Petrucelli L, Disney MD.

Neuron. 2014 Sep 3;83(5):1043-50. doi: 10.1016/j.neuron.2014.07.041. Epub 2014 Aug 14. Erratum in: Neuron. 2014 Oct 1;84(1):239.

45.

Advances in treating amyotrophic lateral sclerosis: insights from pathophysiological studies.

Vucic S, Rothstein JD, Kiernan MC.

Trends Neurosci. 2014 Aug;37(8):433-42. doi: 10.1016/j.tins.2014.05.006. Epub 2014 Jun 11. Review.

PMID:
24927875
46.

Glial cells in amyotrophic lateral sclerosis.

Philips T, Rothstein JD.

Exp Neurol. 2014 Dec;262 Pt B:111-20. doi: 10.1016/j.expneurol.2014.05.015. Epub 2014 May 22. Review.

47.

Safety, pharmacokinetic, and functional effects of the nogo-a monoclonal antibody in amyotrophic lateral sclerosis: a randomized, first-in-human clinical trial.

Meininger V, Pradat PF, Corse A, Al-Sarraj S, Rix Brooks B, Caress JB, Cudkowicz M, Kolb SJ, Lange D, Leigh PN, Meyer T, Milleri S, Morrison KE, Orrell RW, Peters G, Rothstein JD, Shefner J, Lavrov A, Williams N, Overend P, Price J, Bates S, Bullman J, Krull D, Berges A, Abila B, Meno-Tetang G, Wurthner J.

PLoS One. 2014 May 19;9(5):e97803. doi: 10.1371/journal.pone.0097803. eCollection 2014.

48.

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis.

Johnson JO, Pioro EP, Boehringer A, Chia R, Feit H, Renton AE, Pliner HA, Abramzon Y, Marangi G, Winborn BJ, Gibbs JR, Nalls MA, Morgan S, Shoai M, Hardy J, Pittman A, Orrell RW, Malaspina A, Sidle KC, Fratta P, Harms MB, Baloh RH, Pestronk A, Weihl CC, Rogaeva E, Zinman L, Drory VE, Borghero G, Mora G, Calvo A, Rothstein JD; ITALSGEN, Drepper C, Sendtner M, Singleton AB, Taylor JP, Cookson MR, Restagno G, Sabatelli M, Bowser R, Chiò A, Traynor BJ.

Nat Neurosci. 2014 May;17(5):664-666. doi: 10.1038/nn.3688. Epub 2014 Mar 30.

49.

C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

Haeusler AR, Donnelly CJ, Periz G, Simko EA, Shaw PG, Kim MS, Maragakis NJ, Troncoso JC, Pandey A, Sattler R, Rothstein JD, Wang J.

Nature. 2014 Mar 13;507(7491):195-200. doi: 10.1038/nature13124. Epub 2014 Mar 5.

50.

Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models.

Yohay K, Tyler B, Weaver KD, Pardo AC, Gincel D, Blakeley J, Brem H, Rothstein JD.

J Neurosurg. 2014 Apr;120(4):854-63. doi: 10.3171/2013.12.JNS13641. Epub 2014 Jan 31.

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