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Items: 11

1.

An Outward-facing Aromatic Amino Acid is Crucial for Signalling Between the Membrane Spanning and Nucleotide Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1).

Weigl KE, Conseil G, Rothnie AJ, Arama M, Tsfadia Y, Cole SPC.

Mol Pharmacol. 2018 Jul 5. pii: mol.118.112615. doi: 10.1124/mol.118.112615. [Epub ahead of print]

2.

An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles.

Hall SCL, Tognoloni C, Charlton J, Bragginton ÉC, Rothnie AJ, Sridhar P, Wheatley M, Knowles TJ, Arnold T, Edler KJ, Dafforn TR.

Nanoscale. 2018 Jun 7;10(22):10609-10619. doi: 10.1039/c8nr01322e.

3.

Successful outpatient parenteral antibiotic therapy delivery via telemedicine.

Tan SJ, Ingram PR, Rothnie AJ, Whitmore TJ, Robinson JO, Hatch JB, Italiano CM, Heath CH.

J Antimicrob Chemother. 2017 Oct 1;72(10):2898-2901. doi: 10.1093/jac/dkx203.

PMID:
29091189
4.

Structure and function of membrane proteins encapsulated in a polymer-bound lipid bilayer.

Pollock NL, Lee SC, Patel JH, Gulamhussein AA, Rothnie AJ.

Biochim Biophys Acta. 2018 Apr;1860(4):809-817. doi: 10.1016/j.bbamem.2017.08.012. Epub 2017 Sep 1. Review.

PMID:
28865797
5.

Membrane protein extraction and purification using styrene-maleic acid (SMA) copolymer: effect of variations in polymer structure.

Morrison KA, Akram A, Mathews A, Khan ZA, Patel JH, Zhou C, Hardy DJ, Moore-Kelly C, Patel R, Odiba V, Knowles TJ, Javed MU, Chmel NP, Dafforn TR, Rothnie AJ.

Biochem J. 2016 Dec 1;473(23):4349-4360. Epub 2016 Sep 30.

PMID:
27694389
6.

Detergent-Free Membrane Protein Purification.

Rothnie AJ.

Methods Mol Biol. 2016;1432:261-7. doi: 10.1007/978-1-4939-3637-3_16.

PMID:
27485341
7.

Overcoming bottlenecks in the membrane protein structural biology pipeline.

Hardy D, Bill RM, Jawhari A, Rothnie AJ.

Biochem Soc Trans. 2016 Jun 15;44(3):838-44. doi: 10.1042/BST20160049. Review.

PMID:
27284049
8.

Encapsulated membrane proteins: A simplified system for molecular simulation.

Lee SC, Khalid S, Pollock NL, Knowles TJ, Edler K, Rothnie AJ, R T Thomas O, Dafforn TR.

Biochim Biophys Acta. 2016 Oct;1858(10):2549-2557. doi: 10.1016/j.bbamem.2016.02.039. Epub 2016 Mar 3. Review.

9.

The synthesis of recombinant membrane proteins in yeast for structural studies.

Routledge SJ, Mikaliunaite L, Patel A, Clare M, Cartwright SP, Bawa Z, Wilks MD, Low F, Hardy D, Rothnie AJ, Bill RM.

Methods. 2016 Feb 15;95:26-37. doi: 10.1016/j.ymeth.2015.09.027. Epub 2015 Sep 30. Review.

10.

Detergent-free purification of ABC (ATP-binding-cassette) transporters.

Gulati S, Jamshad M, Knowles TJ, Morrison KA, Downing R, Cant N, Collins R, Koenderink JB, Ford RC, Overduin M, Kerr ID, Dafforn TR, Rothnie AJ.

Biochem J. 2014 Jul 15;461(2):269-78. doi: 10.1042/BJ20131477.

PMID:
24758594
11.

Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).

Conseil G, Rothnie AJ, Deeley RG, Cole SP.

Mol Pharmacol. 2009 Feb;75(2):397-406. doi: 10.1124/mol.108.052860. Epub 2008 Nov 17.

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