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Items: 19


Early complement genes are associated with visual system degeneration in multiple sclerosis.

Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De Jager PL, Calabresi PA.

Brain. 2019 Jul 9. pii: awz188. doi: 10.1093/brain/awz188. [Epub ahead of print]


The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry.

Billings CG, Lewis R, Hurdman JA, Condliffe R, Elliot CA, Thompson AAR, Smith IA, Austin M, Armstrong IJ, Hamilton N, Charalampopoulos A, Sabroe I, Swift AJ, Rothman AM, Wild JM, Lawrie A, Waterhouse JC, Kiely DG.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019848649. doi: 10.1177/2045894019848649.


Interleukin-1 beta inhibition with canakinumab and reducing lung cancer-subset analysis of the canakinumab anti-inflammatory thrombosis outcome study trial (CANTOS).

Crossman D, Rothman AMK.

J Thorac Dis. 2018 Sep;10(Suppl 26):S3084-S3087. doi: 10.21037/jtd.2018.07.50. No abstract available.


The impact of patient choice on survival in chronic thromboembolic pulmonary hypertension.

Quadery SR, Swift AJ, Billings CG, Thompson AAR, Elliot CA, Hurdman J, Charalampopoulos A, Sabroe I, Armstrong IJ, Hamilton N, Sephton P, Garrad S, Pepke-Zaba J, Jenkins DP, Screaton N, Rothman AM, Lawrie A, Cleveland T, Thomas S, Rajaram S, Hill C, Davies C, Johns CS, Wild JM, Condliffe R, Kiely DG.

Eur Respir J. 2018 Sep 16;52(3). pii: 1800589. doi: 10.1183/13993003.00589-2018. Print 2018 Sep.


Embedding Autism Spectrum Disorder Diagnosis Within the Medical Home: Decreasing Wait Times Through Streamlined Assessment.

Hine JF, Herrington CG, Rothman AM, Mace RL, Patterson BL, Carlson KL, Warren ZE.

J Autism Dev Disord. 2018 Aug;48(8):2846-2853. doi: 10.1007/s10803-018-3548-3.


Canakinumab for Atherosclerotic Disease.

Rothman AM, Morton AC, Crossman DC; MRC-ILA Heart investigators.

N Engl J Med. 2018 Jan 11;378(2):197-8. doi: 10.1056/NEJMc1714635. No abstract available.


Incremental shuttle walk test distance and autonomic dysfunction predict survival in pulmonary arterial hypertension.

Billings CG, Hurdman JA, Condliffe R, Elliot CA, Smith IA, Austin M, Armstrong IJ, Hamilton N, Charalampopoulos A, Sabroe I, Swift AJ, Rothman AM, Wild JM, Lawrie A, Waterhouse JC, Kiely DG.

J Heart Lung Transplant. 2017 Aug;36(8):871-879. doi: 10.1016/j.healun.2017.04.008. Epub 2017 Apr 24.


miRNA-140-5p: new avenue for pulmonary arterial hypertension drug development?

Rothman AM, Rowlands DJ, Lawrie A.

Epigenomics. 2016 Oct;8(10):1311-1313. Epub 2016 Sep 7. No abstract available.


MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.

Rothman AM, Arnold ND, Pickworth JA, Iremonger J, Ciuclan L, Allen RM, Guth-Gundel S, Southwood M, Morrell NW, Thomas M, Francis SE, Rowlands DJ, Lawrie A.

J Clin Invest. 2016 Jul 1;126(7):2495-508. doi: 10.1172/JCI83361. Epub 2016 May 23.


Response to Letter Regarding Article, "Hemodynamic, Functional, and Clinical Responses to Pulmonary Artery Denervation in Patients With Pulmonary Arterial Hypertension of Different Causes: Phase II Results From the Pulmonary Artery Denervation-1 Study".

Chen SL, Zhang H, Xie DJ, Zhang J, Zhou L, Rothman AM, Stone GW.

Circ Cardiovasc Interv. 2016 Jan;9(1):e003463. doi: 10.1161/CIRCINTERVENTIONS.115.003463. No abstract available.


Pulmonary Artery Denervation Attenuates Pulmonary Arterial Remodeling in Dogs With Pulmonary Arterial Hypertension Induced by Dehydrogenized Monocrotaline.

Zhou L, Zhang J, Jiang XM, Xie DJ, Wang JS, Li L, Li B, Wang ZM, Rothman AMK, Lawrie A, Chen SL.

JACC Cardiovasc Interv. 2015 Dec 28;8(15):2013-2023. doi: 10.1016/j.jcin.2015.09.015.


Hemodynamic, functional, and clinical responses to pulmonary artery denervation in patients with pulmonary arterial hypertension of different causes: phase II results from the Pulmonary Artery Denervation-1 study.

Chen SL, Zhang H, Xie DJ, Zhang J, Zhou L, Rothman AM, Stone GW.

Circ Cardiovasc Interv. 2015 Nov;8(11):e002837. doi: 10.1161/CIRCINTERVENTIONS.115.002837.


Pulmonary artery denervation reduces pulmonary artery pressure and induces histological changes in an acute porcine model of pulmonary hypertension.

Rothman AM, Arnold ND, Chang W, Watson O, Swift AJ, Condliffe R, Elliot CA, Kiely DG, Suvarna SK, Gunn J, Lawrie A.

Circ Cardiovasc Interv. 2015 Nov;8(11):e002569. doi: 10.1161/CIRCINTERVENTIONS.115.002569.


The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study.

Morton AC, Rothman AM, Greenwood JP, Gunn J, Chase A, Clarke B, Hall AS, Fox K, Foley C, Banya W, Wang D, Flather MD, Crossman DC.

Eur Heart J. 2015 Feb 7;36(6):377-84. doi: 10.1093/eurheartj/ehu272. Epub 2014 Jul 30.


MicroRNA in pulmonary vascular disease.

Rothman AM, Chico TJ, Lawrie A.

Prog Mol Biol Transl Sci. 2014;124:43-63. doi: 10.1016/B978-0-12-386930-2.00003-3. Review.


Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling.

Watson O, Novodvorsky P, Gray C, Rothman AM, Lawrie A, Crossman DC, Haase A, McMahon K, Gering M, Van Eeden FJ, Chico TJ.

Cardiovasc Res. 2013 Nov 1;100(2):252-61. doi: 10.1093/cvr/cvt170. Epub 2013 Jul 30.


Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers.

Thiel KW, Hernandez LI, Dassie JP, Thiel WH, Liu X, Stockdale KR, Rothman AM, Hernandez FJ, McNamara JO 2nd, Giangrande PH.

Nucleic Acids Res. 2012 Jul;40(13):6319-37. doi: 10.1093/nar/gks294. Epub 2012 Mar 30.


Intracellular retention of mutant retinoschisin is the pathological mechanism underlying X-linked retinoschisis.

Wang T, Waters CT, Rothman AM, Jakins TJ, Römisch K, Trump D.

Hum Mol Genet. 2002 Nov 15;11(24):3097-105.


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