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Items: 14

1.

Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo.

Rothchild AC, Olson GS, Nemeth J, Amon LM, Mai D, Gold ES, Diercks AH, Aderem A.

Sci Immunol. 2019 Jul 26;4(37). pii: eaaw6693. doi: 10.1126/sciimmunol.aaw6693.

PMID:
31350281
2.

Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation.

Peterson EJ, Bailo R, Rothchild AC, Arrieta-Ortiz ML, Kaur A, Pan M, Mai D, Abidi AA, Cooper C, Aderem A, Bhatt A, Baliga NS.

Mol Syst Biol. 2019 Mar 4;15(3):e8584. doi: 10.15252/msb.20188584.

3.

Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection.

Rothchild AC, Stowell B, Goyal G, Nunes-Alves C, Yang Q, Papavinasasundaram K, Sassetti CM, Dranoff G, Chen X, Lee J, Behar SM.

MBio. 2017 Oct 24;8(5). pii: e01514-17. doi: 10.1128/mBio.01514-17.

4.

MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis.

Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181. Epub 2016 Sep 28.

5.

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.

Nunes-Alves C, Booty MG, Carpenter SM, Rothchild AC, Martin CJ, Desjardins D, Steblenko K, Kløverpris HN, Madansein R, Ramsuran D, Leslie A, Correia-Neves M, Behar SM.

PLoS Pathog. 2015 May 6;11(5):e1004849. doi: 10.1371/journal.ppat.1004849. eCollection 2015 May. Erratum in: PLoS Pathog. 2015 Sep;11(9):e1005144.

6.

In search of a new paradigm for protective immunity to TB.

Nunes-Alves C, Booty MG, Carpenter SM, Jayaraman P, Rothchild AC, Behar SM.

Nat Rev Microbiol. 2014 Apr;12(4):289-99. doi: 10.1038/nrmicro3230. Epub 2014 Mar 3. Review.

7.

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.

Rothchild AC, Jayaraman P, Nunes-Alves C, Behar SM.

PLoS Pathog. 2014 Jan;10(1):e1003805. doi: 10.1371/journal.ppat.1003805. Epub 2014 Jan 2.

8.

Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing.

Zhang YJ, Reddy MC, Ioerger TR, Rothchild AC, Dartois V, Schuster BM, Trauner A, Wallis D, Galaviz S, Huttenhower C, Sacchettini JC, Behar SM, Rubin EJ.

Cell. 2013 Dec 5;155(6):1296-308. doi: 10.1016/j.cell.2013.10.045.

9.

EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity.

Garces A, Atmakuri K, Chase MR, Woodworth JS, Krastins B, Rothchild AC, Ramsdell TL, Lopez MF, Behar SM, Sarracino DA, Fortune SM.

PLoS Pathog. 2010 Jun 24;6(6):e1000957. doi: 10.1371/journal.ppat.1000957.

10.

Persistent low-level viremia in HIV-1 elite controllers and relationship to immunologic parameters.

Pereyra F, Palmer S, Miura T, Block BL, Wiegand A, Rothchild AC, Baker B, Rosenberg R, Cutrell E, Seaman MS, Coffin JM, Walker BD.

J Infect Dis. 2009 Sep 15;200(6):984-90. doi: 10.1086/605446.

11.

Differential neutralization of human immunodeficiency virus (HIV) replication in autologous CD4 T cells by HIV-specific cytotoxic T lymphocytes.

Chen H, Piechocka-Trocha A, Miura T, Brockman MA, Julg BD, Baker BM, Rothchild AC, Block BL, Schneidewind A, Koibuchi T, Pereyra F, Allen TM, Walker BD.

J Virol. 2009 Apr;83(7):3138-49. doi: 10.1128/JVI.02073-08. Epub 2009 Jan 21.

12.

HLA-B57/B*5801 human immunodeficiency virus type 1 elite controllers select for rare gag variants associated with reduced viral replication capacity and strong cytotoxic T-lymphocyte [corrected] recognition.

Miura T, Brockman MA, Schneidewind A, Lobritz M, Pereyra F, Rathod A, Block BL, Brumme ZL, Brumme CJ, Baker B, Rothchild AC, Li B, Trocha A, Cutrell E, Frahm N, Brander C, Toth I, Arts EJ, Allen TM, Walker BD.

J Virol. 2009 Mar;83(6):2743-55. doi: 10.1128/JVI.02265-08. Epub 2008 Dec 30. Erratum in: J Virol. 2009 Jun;83(11):5961.

13.

Elite control of HIV infection: implications for vaccine design.

Baker BM, Block BL, Rothchild AC, Walker BD.

Expert Opin Biol Ther. 2009 Jan;9(1):55-69. doi: 10.1517/14712590802571928 . Review.

14.

Genetic characterization of human immunodeficiency virus type 1 in elite controllers: lack of gross genetic defects or common amino acid changes.

Miura T, Brockman MA, Brumme CJ, Brumme ZL, Carlson JM, Pereyra F, Trocha A, Addo MM, Block BL, Rothchild AC, Baker BM, Flynn T, Schneidewind A, Li B, Wang YE, Heckerman D, Allen TM, Walker BD.

J Virol. 2008 Sep;82(17):8422-30. doi: 10.1128/JVI.00535-08. Epub 2008 Jun 18.

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