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Items: 1 to 50 of 75

1.

Impaired Mitochondrial Dynamics And Mitophagy In Neuronal Models Of Tuberous Sclerosis Complex.

Ebrahimi-Fakhari D, Saffari A, Wahlster L, DiNardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.

Cell Rep. 2016 Nov 15;17(8):2162. doi: 10.1016/j.celrep.2016.10.051. No abstract available.

2.

Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex.

Ebrahimi-Fakhari D, Saffari A, Wahlster L, Di Nardo A, Turner D, Lewis TL Jr, Conrad C, Rothberg JM, Lipton JO, Kölker S, Hoffmann GF, Han MJ, Polleux F, Sahin M.

Cell Rep. 2016 Oct 18;17(4):1053-1070. doi: 10.1016/j.celrep.2016.09.054. Erratum in: Cell Rep. 2016 Nov 15;17 (8):2162.

3.

Massively parallel ("next-generation") DNA sequencing.

Gould Rothberg BE, Rothberg JM.

Clin Chem. 2015 Jul;61(7):997-8. doi: 10.1373/clinchem.2014.237461. Epub 2015 Apr 28. Review. No abstract available.

4.

Acid-mediated tumor proteolysis: contribution of cysteine cathepsins.

Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF.

Neoplasia. 2013 Oct;15(10):1125-37.

5.

Radiation resistance of sequencing chips for in situ life detection.

Carr CE, Rowedder H, Lui CS, Zlatkovsky I, Papalias CW, Bolander J, Myers JW, Bustillo J, Rothberg JM, Zuber MT, Ruvkun G.

Astrobiology. 2013 Jun;13(6):560-9. doi: 10.1089/ast.2012.0923. Epub 2013 Jun 4.

PMID:
23734755
6.

Acidity generated by the tumor microenvironment drives local invasion.

Estrella V, Chen T, Lloyd M, Wojtkowiak J, Cornnell HH, Ibrahim-Hashim A, Bailey K, Balagurunathan Y, Rothberg JM, Sloane BF, Johnson J, Gatenby RA, Gillies RJ.

Cancer Res. 2013 Mar 1;73(5):1524-35. doi: 10.1158/0008-5472.CAN-12-2796. Epub 2013 Jan 3.

7.

Progress in ion torrent semiconductor chip based sequencing.

Merriman B; Ion Torrent R&D Team, Rothberg JM.

Electrophoresis. 2012 Dec;33(23):3397-417. doi: 10.1002/elps.201200424. Review. Erratum in: Electrophoresis. 2013 Feb;34(4):619.

PMID:
23208921
8.

Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments.

Wojtkowiak JW, Rothberg JM, Kumar V, Schramm KJ, Haller E, Proemsey JB, Lloyd MC, Sloane BF, Gillies RJ.

Cancer Res. 2012 Aug 15;72(16):3938-47. doi: 10.1158/0008-5472.CAN-11-3881. Epub 2012 Jun 19.

9.

3D/4D functional imaging of tumor-associated proteolysis: impact of microenvironment.

Moin K, Sameni M, Victor BC, Rothberg JM, Mattingly RR, Sloane BF.

Methods Enzymol. 2012;506:175-94. doi: 10.1016/B978-0-12-391856-7.00034-2.

10.

Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironment.

Rothberg JM, Sameni M, Moin K, Sloane BF.

Biochim Biophys Acta. 2012 Jan;1824(1):123-32. doi: 10.1016/j.bbapap.2011.07.025. Epub 2011 Aug 5. Review.

11.

Prospective genomic characterization of the German enterohemorrhagic Escherichia coli O104:H4 outbreak by rapid next generation sequencing technology.

Mellmann A, Harmsen D, Cummings CA, Zentz EB, Leopold SR, Rico A, Prior K, Szczepanowski R, Ji Y, Zhang W, McLaughlin SF, Henkhaus JK, Leopold B, Bielaszewska M, Prager R, Brzoska PM, Moore RL, Guenther S, Rothberg JM, Karch H.

PLoS One. 2011;6(7):e22751. doi: 10.1371/journal.pone.0022751. Epub 2011 Jul 20.

12.

An integrated semiconductor device enabling non-optical genome sequencing.

Rothberg JM, Hinz W, Rearick TM, Schultz J, Mileski W, Davey M, Leamon JH, Johnson K, Milgrew MJ, Edwards M, Hoon J, Simons JF, Marran D, Myers JW, Davidson JF, Branting A, Nobile JR, Puc BP, Light D, Clark TA, Huber M, Branciforte JT, Stoner IB, Cawley SE, Lyons M, Fu Y, Homer N, Sedova M, Miao X, Reed B, Sabina J, Feierstein E, Schorn M, Alanjary M, Dimalanta E, Dressman D, Kasinskas R, Sokolsky T, Fidanza JA, Namsaraev E, McKernan KJ, Williams A, Roth GT, Bustillo J.

Nature. 2011 Jul 20;475(7356):348-52. doi: 10.1038/nature10242.

PMID:
21776081
13.

Droplet microfluidic technology for single-cell high-throughput screening.

Brouzes E, Medkova M, Savenelli N, Marran D, Twardowski M, Hutchison JB, Rothberg JM, Link DR, Perrimon N, Samuels ML.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14195-200. doi: 10.1073/pnas.0903542106. Epub 2009 Jul 15.

14.

High-throughput quantitative polymerase chain reaction in picoliter droplets.

Kiss MM, Ortoleva-Donnelly L, Beer NR, Warner J, Bailey CG, Colston BW, Rothberg JM, Link DR, Leamon JH.

Anal Chem. 2008 Dec 1;80(23):8975-81.

15.

Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment-naive patients significantly impact treatment outcomes.

Simen BB, Simons JF, Hullsiek KH, Novak RM, Macarthur RD, Baxter JD, Huang C, Lubeski C, Turenchalk GS, Braverman MS, Desany B, Rothberg JM, Egholm M, Kozal MJ; Terry Beirn Community Programs for Clinical Research on AIDS.

J Infect Dis. 2009 Mar 1;199(5):693-701. doi: 10.1086/596736.

PMID:
19210162
16.

The development and impact of 454 sequencing.

Rothberg JM, Leamon JH.

Nat Biotechnol. 2008 Oct;26(10):1117-24. doi: 10.1038/nbt1485.

PMID:
18846085
17.

A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing.

Green RE, Malaspinas AS, Krause J, Briggs AW, Johnson PL, Uhler C, Meyer M, Good JM, Maricic T, Stenzel U, Prüfer K, Siebauer M, Burbano HA, Ronan M, Rothberg JM, Egholm M, Rudan P, Brajković D, Kućan Z, Gusić I, Wikström M, Laakkonen L, Kelso J, Slatkin M, Pääbo S.

Cell. 2008 Aug 8;134(3):416-26. doi: 10.1016/j.cell.2008.06.021.

18.

The complete genome of an individual by massively parallel DNA sequencing.

Wheeler DA, Srinivasan M, Egholm M, Shen Y, Chen L, McGuire A, He W, Chen YJ, Makhijani V, Roth GT, Gomes X, Tartaro K, Niazi F, Turcotte CL, Irzyk GP, Lupski JR, Chinault C, Song XZ, Liu Y, Yuan Y, Nazareth L, Qin X, Muzny DM, Margulies M, Weinstock GM, Gibbs RA, Rothberg JM.

Nature. 2008 Apr 17;452(7189):872-6. doi: 10.1038/nature06884.

PMID:
18421352
19.

Cramming more sequencing reactions onto microreactor chips.

Leamon JH, Rothberg JM.

Chem Rev. 2007 Aug;107(8):3367-76. Epub 2007 Jul 10. Review. No abstract available.

PMID:
17622174
20.

Analysis of one million base pairs of Neanderthal DNA.

Green RE, Krause J, Ptak SE, Briggs AW, Ronan MT, Simons JF, Du L, Egholm M, Rothberg JM, Paunovic M, Pääbo S.

Nature. 2006 Nov 16;444(7117):330-6.

PMID:
17108958
21.

Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA.

Stiller M, Green RE, Ronan M, Simons JF, Du L, He W, Egholm M, Rothberg JM, Keates SG, Ovodov ND, Antipina EE, Baryshnikov GF, Kuzmin YV, Vasilevski AA, Wuenschell GE, Termini J, Hofreiter M, Jaenicke-Després V, Pääbo S.

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13578-84. Epub 2006 Aug 25. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14977.

22.

Assessment of whole genome amplification-induced bias through high-throughput, massively parallel whole genome sequencing.

Pinard R, de Winter A, Sarkis GJ, Gerstein MB, Tartaro KR, Plant RN, Egholm M, Rothberg JM, Leamon JH.

BMC Genomics. 2006 Aug 23;7:216.

23.

Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors.

Thomas RK, Greulich H, Yuza Y, Lee JC, Tengs T, Feng W, Chen TH, Nickerson E, Simons J, Egholm M, Rothberg JM, Sellers WR, Meyerson ML.

Cold Spring Harb Symp Quant Biol. 2005;70:73-81.

PMID:
16869740
24.

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing.

Thomas RK, Nickerson E, Simons JF, Jänne PA, Tengs T, Yuza Y, Garraway LA, LaFramboise T, Lee JC, Shah K, O'Neill K, Sasaki H, Lindeman N, Wong KK, Borras AM, Gutmann EJ, Dragnev KH, DeBiasi R, Chen TH, Glatt KA, Greulich H, Desany B, Lubeski CK, Brockman W, Alvarez P, Hutchison SK, Leamon JH, Ronan MT, Turenchalk GS, Egholm M, Sellers WR, Rothberg JM, Meyerson M.

Nat Med. 2006 Jul;12(7):852-5. Epub 2006 Jun 25. Erratum in: Nat Med. 2006 Oct;12(10):1220.

PMID:
16799556
25.

Overview: methods and applications for droplet compartmentalization of biology.

Leamon JH, Link DR, Egholm M, Rothberg JM.

Nat Methods. 2006 Jul;3(7):541-3.

PMID:
16791212
26.

Genome sequencing in microfabricated high-density picolitre reactors.

Margulies M, Egholm M, Altman WE, Attiya S, Bader JS, Bemben LA, Berka J, Braverman MS, Chen YJ, Chen Z, Dewell SB, Du L, Fierro JM, Gomes XV, Godwin BC, He W, Helgesen S, Ho CH, Irzyk GP, Jando SC, Alenquer ML, Jarvie TP, Jirage KB, Kim JB, Knight JR, Lanza JR, Leamon JH, Lefkowitz SM, Lei M, Li J, Lohman KL, Lu H, Makhijani VB, McDade KE, McKenna MP, Myers EW, Nickerson E, Nobile JR, Plant R, Puc BP, Ronan MT, Roth GT, Sarkis GJ, Simons JF, Simpson JW, Srinivasan M, Tartaro KR, Tomasz A, Vogt KA, Volkmer GA, Wang SH, Wang Y, Weiner MP, Yu P, Begley RF, Rothberg JM.

Nature. 2005 Sep 15;437(7057):376-80. Epub 2005 Jul 31. Erratum in: Nature. 2006 May 4;441(7089):120. Ho, Chun He [corrected to Ho, Chun Heen].

27.

A quantitative genomic expression analysis platform for multiplexed in vitro prediction of drug action.

Gunther EC, Stone DJ, Rothberg JM, Gerwien RW.

Pharmacogenomics J. 2005;5(2):126-34.

PMID:
15724147
28.

Gaining confidence in high-throughput protein interaction networks.

Bader JS, Chaudhuri A, Rothberg JM, Chant J.

Nat Biotechnol. 2004 Jan;22(1):78-85. Epub 2003 Dec 14.

PMID:
14704708
29.

A massively parallel PicoTiterPlate based platform for discrete picoliter-scale polymerase chain reactions.

Leamon JH, Lee WL, Tartaro KR, Lanza JR, Sarkis GJ, deWinter AD, Berka J, Weiner M, Rothberg JM, Lohman KL.

Electrophoresis. 2003 Nov;24(21):3769-77. Erratum in: Electrophoresis. 2004 Apr;25(7-8):1176.

PMID:
14613204
30.

A protein interaction map of Drosophila melanogaster.

Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, Li Y, Hao YL, Ooi CE, Godwin B, Vitols E, Vijayadamodar G, Pochart P, Machineni H, Welsh M, Kong Y, Zerhusen B, Malcolm R, Varrone Z, Collis A, Minto M, Burgess S, McDaniel L, Stimpson E, Spriggs F, Williams J, Neurath K, Ioime N, Agee M, Voss E, Furtak K, Renzulli R, Aanensen N, Carrolla S, Bickelhaupt E, Lazovatsky Y, DaSilva A, Zhong J, Stanyon CA, Finley RL Jr, White KP, Braverman M, Jarvie T, Gold S, Leach M, Knight J, Shimkets RA, McKenna MP, Chant J, Rothberg JM.

Science. 2003 Dec 5;302(5651):1727-36. Epub 2003 Nov 6.

31.

Suicidal admissions in the United States military.

Ritchie EC, Keppler WC, Rothberg JM.

Mil Med. 2003 Mar;168(3):177-81.

PMID:
12685680
32.

The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

Tchernev VT, Mansfield TA, Giot L, Kumar AM, Nandabalan K, Li Y, Mishra VS, Detter JC, Rothberg JM, Wallace MR, Southwick FS, Kingsmore SF.

Mol Med. 2002 Jan;8(1):56-64.

33.

The characterization of PPAR alpha ligand drug action in an in vivo model by comprehensive differential gene expression profiling.

Gould Rothberg BE, Sundseth SS, DiPippo VA, Brown PJ, Winegar DA, Gottshalk WK, Shenoy SG, Rothberg JM.

Funct Integr Genomics. 2001 Sep;1(5):294-304.

PMID:
11793248
34.

PDGF-D, a new protease-activated growth factor.

LaRochelle WJ, Jeffers M, McDonald WF, Chillakuru RA, Giese NA, Lokker NA, Sullivan C, Boldog FL, Yang M, Vernet C, Burgess CE, Fernandes E, Deegler LL, Rittman B, Shimkets J, Shimkets RA, Rothberg JM, Lichenstein HS.

Nat Cell Biol. 2001 May;3(5):517-21.

PMID:
11331882
35.

Implications of oncogenomics for cancer research and clinical oncology.

Herrmann JL, Rastelli L, Burgess CE, Fernandez EE, Rothberg BE, Rothberg JM, Shimkets RA.

Cancer J. 2001 Jan-Feb;7(1):40-51. Review.

PMID:
11269647
36.

Suicide statistics.

Rothberg JM.

Suicide Life Threat Behav. 1999 Autumn;29(3):286. No abstract available.

PMID:
10712159
37.

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae.

Uetz P, Giot L, Cagney G, Mansfield TA, Judson RS, Knight JR, Lockshon D, Narayan V, Srinivasan M, Pochart P, Qureshi-Emili A, Li Y, Godwin B, Conover D, Kalbfleisch T, Vijayadamodar G, Yang M, Johnston M, Fields S, Rothberg JM.

Nature. 2000 Feb 10;403(6770):623-7.

PMID:
10688190
38.

A transmission imaging spectrograph and microfabricated channel system for DNA analysis.

Simpson JW, Ruiz-Martinez MC, Mulhern GT, Berka J, Latimer DR, Ball JA, Rothberg JM, Went GT.

Electrophoresis. 2000 Jan;21(1):135-49.

PMID:
10634480
39.

Differential transport of DNA by a rectified Brownian motion device.

Hammond RW, Bader JS, Henck SA, Deem MW, McDermott GA, Bustillo JM, Rothberg JM.

Electrophoresis. 2000 Jan;21(1):74-80.

PMID:
10634472
40.

DNA transport by a micromachined Brownian ratchet device.

Bader JS, Hammond RW, Henck SA, Deem MW, McDermott GA, Bustillo JM, Simpson JW, Mulhern GT, Rothberg JM.

Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13165-9.

41.

Gene expression analysis by transcript profiling coupled to a gene database query.

Shimkets RA, Lowe DG, Tai JT, Sehl P, Jin H, Yang R, Predki PF, Rothberg BE, Murtha MT, Roth ME, Shenoy SG, Windemuth A, Simpson JW, Simons JF, Daley MP, Gold SA, McKenna MP, Hillan K, Went GT, Rothberg JM.

Nat Biotechnol. 1999 Aug;17(8):798-803.

PMID:
10429247
42.

The Army psychological autopsy: then and now.

Rothberg JM.

Mil Med. 1998 Jun;163(6):427-33.

PMID:
9640042
43.

Phase II trial of recombinant human interleukin-2 and interferon-alpha-2a: implications for the treatment of patients with metastatic melanoma.

Eton O, Talpaz M, Lee KH, Rothberg JM, Brell JM, Benjamin RS.

Cancer. 1996 Mar 1;77(5):893-9.

PMID:
8608480
44.
45.
47.

Compliance with consultations in a military psychiatry clinic.

Koshes RJ, Rothberg JM.

Mil Med. 1994 Apr;159(4):310-3.

PMID:
20058427
48.

Desert Shield deployment and social problems on a U.S. Army combat support post.

Rothberg JM, Koshes RJ, Shanahan J, Christman K.

Mil Med. 1994 Mar;159(3):246-8.

PMID:
8041475
49.

Witnessed suicides.

McDowell CP, Rothberg JM, Koshes RJ.

Suicide Life Threat Behav. 1994 Fall;24(3):213-23.

PMID:
7825194

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