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Association of Prospective Risk for Chronic PTSD Symptoms With Low TNFα and IFNγ Concentrations in the Immediate Aftermath of Trauma Exposure.

Michopoulos V, Beurel E, Gould F, Dhabhar FS, Schultebraucks K, Galatzer-Levy I, Rothbaum BO, Ressler KJ, Nemeroff CB.

Am J Psychiatry. 2019 Jul 29:appiajp201919010039. doi: 10.1176/appi.ajp.2019.19010039. [Epub ahead of print]


Structural connectivity and risk for anhedonia after trauma: A prospective study and replication.

Fani N, Michopoulos V, van Rooij SJH, Clendinen C, Hardy RA, Jovanovic T, Rothbaum BO, Ressler KJ, Stevens JS.

J Psychiatr Res. 2019 Sep;116:34-41. doi: 10.1016/j.jpsychires.2019.05.009. Epub 2019 May 14.


Increased Skin Conductance Response in the Immediate Aftermath of Trauma Predicts PTSD Risk.

Hinrichs R, van Rooij SJ, Michopoulos V, Schultebraucks K, Winters S, Maples-Keller J, Rothbaum AO, Stevens JS, Galatzer-Levy I, Rothbaum BO, Ressler KJ, Jovanovic T.

Chronic Stress (Thousand Oaks). 2019 Jan-Dec;3. doi: 10.1177/2470547019844441. Epub 2019 Apr 24.


Using fMRI connectivity to define a treatment-resistant form of post-traumatic stress disorder.

Etkin A, Maron-Katz A, Wu W, Fonzo GA, Huemer J, Vértes PE, Patenaude B, Richiardi J, Goodkind MS, Keller CJ, Ramos-Cejudo J, Zaiko YV, Peng KK, Shpigel E, Longwell P, Toll RT, Thompson A, Zack S, Gonzalez B, Edelstein R, Chen J, Akingbade I, Weiss E, Hart R, Mann S, Durkin K, Baete SH, Boada FE, Genfi A, Autea J, Newman J, Oathes DJ, Lindley SE, Abu-Amara D, Arnow BA, Crossley N, Hallmayer J, Fossati S, Rothbaum BO, Marmar CR, Bullmore ET, O'Hara R.

Sci Transl Med. 2019 Apr 3;11(486). pii: eaal3236. doi: 10.1126/scitranslmed.aal3236.


Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients.

Jovanovic T, Duncan EJ, Kaye J, Garza K, Norrholm SD, Inslicht SS, Neylan TC, Mathew SJ, Iosifescu D, Rothbaum BO, Mayberg HS, Dunlop BW.

Psychophysiology. 2019 Feb 26:e13356. doi: 10.1111/psyp.13356. [Epub ahead of print]


Effect size matters: a key neglected indicator of comparative trial quality.

Tuerk PW, Rauch SAM, Rothbaum BO.

Lancet Psychiatry. 2019 Feb;6(2):e4. doi: 10.1016/S2215-0366(18)30505-4. No abstract available.


Elevated resting blood pressure augments autonomic imbalance in posttraumatic stress disorder.

Fonkoue IT, Norrholm SD, Marvar PJ, Li Y, Kankam ML, Rothbaum BO, Park J.

Am J Physiol Regul Integr Comp Physiol. 2018 Dec 1;315(6):R1272-R1280. doi: 10.1152/ajpregu.00173.2018. Epub 2018 Oct 10.


When translational neuroscience fails in the clinic: Dexamethasone prior to virtual reality exposure therapy increases drop-out rates.

Maples-Keller JL, Jovanovic T, Dunlop BW, Rauch S, Yasinski C, Michopoulos V, Coghlan C, Norrholm S, Rizzo AS, Ressler K, Rothbaum BO.

J Anxiety Disord. 2019 Jan;61:89-97. doi: 10.1016/j.janxdis.2018.10.006. Epub 2018 Oct 29.


Efficacy of Prolonged Exposure Therapy, Sertraline Hydrochloride, and Their Combination Among Combat Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial.

Rauch SAM, Kim HM, Powell C, Tuerk PW, Simon NM, Acierno R, Allard CB, Norman SB, Venners MR, Rothbaum BO, Stein MB, Porter K, Martis B, King AP, Liberzon I, Phan KL, Hoge CW.

JAMA Psychiatry. 2019 Feb 1;76(2):117-126. doi: 10.1001/jamapsychiatry.2018.3412.


Nausea in the peri-traumatic period is associated with prospective risk for PTSD symptom development.

Michopoulos V, Maples-Keller J, Roger EI, Beaudoin FL, Sumner JA, Rothbaum BO, Hudak L, Gillespie CF, Kronish IM, McLean SA, Ressler KJ.

Neuropsychopharmacology. 2019 Mar;44(4):668-673. doi: 10.1038/s41386-018-0276-5. Epub 2018 Nov 21.


Treating PTSD: A Review of Evidence-Based Psychotherapy Interventions.

Watkins LE, Sprang KR, Rothbaum BO.

Front Behav Neurosci. 2018 Nov 2;12:258. doi: 10.3389/fnbeh.2018.00258. eCollection 2018.


DNA methylation levels are associated with CRF1 receptor antagonist treatment outcome in women with post-traumatic stress disorder.

Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB.

Clin Epigenetics. 2018 Nov 3;10(1):136. doi: 10.1186/s13148-018-0569-x.


Elevated resting blood pressure augments autonomic imbalance in posttraumatic stress disorder.

Fonkoue IT, Norrholm SD, Marvar PJ, Li Y, Kankam ML, Rothbaum BO, Park J.

Am J Physiol Regul Integr Comp Physiol. 2018 Dec 1;315(6):R1272-R1280. doi: 10.1152/ajpregu.00173.2018. Epub 2018 Oct 10.


Dire Need for New and Improved Therapies for PTSD: Response to Markowitz.

Stein MB, Rothbaum BO.

Am J Psychiatry. 2018 Oct 1;175(10):1022-1023. doi: 10.1176/appi.ajp.2018.18070773r. No abstract available.


Recent advances in virtual reality therapy for anxiety and related disorders: Introduction to the special issue.

Powers MB, Rothbaum BO.

J Anxiety Disord. 2019 Jan;61:1-2. doi: 10.1016/j.janxdis.2018.08.007. Epub 2018 Aug 23. No abstract available.


Temporal Stability of Cognitive Functioning and Functional Capacity in Women with Posttraumatic Stress Disorder.

Gould F, Dunlop BW, Rosenthal JB, Iosifescu DV, Mathew SJ, Neylan TC, Rothbaum BO, Nemeroff CB, Harvey PD.

Arch Clin Neuropsychol. 2019 Jun 1;34(4):539-547. doi: 10.1093/arclin/acy064.


In session extinction and outcome in Virtual Reality Exposure Therapy for PTSD.

Rauch SAM, Koola C, Post L, Yasinski C, Norrholm SD, Black K, Rothbaum BO.

Behav Res Ther. 2018 Oct;109:1-9. doi: 10.1016/j.brat.2018.07.003. Epub 2018 Jul 20.


You can do that?!: Feasibility of virtual reality exposure therapy in the treatment of PTSD due to military sexual trauma.

Loucks L, Yasinski C, Norrholm SD, Maples-Keller J, Post L, Zwiebach L, Fiorillo D, Goodlin M, Jovanovic T, Rizzo AA, Rothbaum BO.

J Anxiety Disord. 2019 Jan;61:55-63. doi: 10.1016/j.janxdis.2018.06.004. Epub 2018 Jun 18.


Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) and R(-) MDMA on actigraphy-based daytime activity and sleep parameters in rhesus monkeys.

Berro LF, Shields H, Odabas-Geldiay M, Rothbaum BO, Andersen ML, Howell LL.

Exp Clin Psychopharmacol. 2018 Aug;26(4):410-420. doi: 10.1037/pha0000196. Epub 2018 Jun 25.


Does virtual reality increase emotional engagement during exposure for PTSD? Subjective distress during prolonged and virtual reality exposure therapy.

Reger GM, Smolenski D, Norr A, Katz A, Buck B, Rothbaum BO.

J Anxiety Disord. 2019 Jan;61:75-81. doi: 10.1016/j.janxdis.2018.06.001. Epub 2018 Jun 8.


175 Years of Progress in PTSD Therapeutics: Learning From the Past.

Stein MB, Rothbaum BO.

Am J Psychiatry. 2018 Jun 1;175(6):508-516. doi: 10.1176/appi.ajp.2017.17080955. Review.


Psychotherapy for PTSD: An evidence-based guide to a theranostic approach to treatment.

Goodnight JRM, Ragsdale KA, Rauch SAM, Rothbaum BO.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jan 10;88:418-426. doi: 10.1016/j.pnpbp.2018.05.006. Epub 2018 May 18. Review.


Virtual reality exposure versus prolonged exposure for PTSD: Which treatment for whom?

Norr AM, Smolenski DJ, Katz AC, Rizzo AA, Rothbaum BO, Difede J, Koenen-Woods P, Reger MA, Reger GM.

Depress Anxiety. 2018 Jun;35(6):523-529. doi: 10.1002/da.22751. Epub 2018 May 7.


Acute effects of device-guided slow breathing on sympathetic nerve activity and baroreflex sensitivity in posttraumatic stress disorder.

Fonkoue IT, Marvar PJ, Norrholm SD, Kankam ML, Li Y, DaCosta D, Rothbaum BO, Park J.

Am J Physiol Heart Circ Physiol. 2018 Jul 1;315(1):H141-H149. doi: 10.1152/ajpheart.00098.2018. Epub 2018 Apr 13.


Narratives in the Immediate Aftermath of Traumatic Injury: Markers of Ongoing Depressive and Posttraumatic Stress Disorder Symptoms.

Booker JA, Graci ME, Hudak LA, Jovanovic T, Rothbaum BO, Ressler KJ, Fivush R, Stevens J.

J Trauma Stress. 2018 Apr;31(2):273-285. doi: 10.1002/jts.22271. Epub 2018 Apr 6.


Designing a Resilience Program for Critical Care Nurses.

Mealer M, Hodapp R, Conrad D, Dimidjian S, Rothbaum BO, Moss M.

AACN Adv Crit Care. 2017 Winter;28(4):359-365. doi: 10.4037/aacnacc2017252.


The Role of the Hippocampus in Predicting Future Posttraumatic Stress Disorder Symptoms in Recently Traumatized Civilians.

van Rooij SJH, Stevens JS, Ely TD, Hinrichs R, Michopoulos V, Winters SJ, Ogbonmwan YE, Shin J, Nugent NR, Hudak LA, Rothbaum BO, Ressler KJ, Jovanovic T.

Biol Psychiatry. 2018 Jul 15;84(2):106-115. doi: 10.1016/j.biopsych.2017.09.005. Epub 2017 Sep 20.


Integrating biological treatment mechanisms into randomized clinical trials: Design of PROGrESS (PROlonGed ExpoSure and Sertraline Trial).

Rauch SAM, Simon NM, Kim HM, Acierno R, King AP, Norman SB, Venners MR, Porter K, Phan KL, Tuerk PW, Allard C, Liberzon I, Rothbaum BO, Martis B, Stein MB, Hoge CW.

Contemp Clin Trials. 2018 Jan;64:128-138. doi: 10.1016/j.cct.2017.10.013. Epub 2017 Oct 29.


Psychological and psychobiological responses to immediate early intervention in the emergency department: Case report of one-session exposure therapy for the prevention of PTSD.

Post LM, Michopoulos V, Stevens JS, Reddy R, Maples JL, Morgan JR, Rothbaum AO, Jovanovic T, Ressler KJ, Rothbaum BO.

Pract Innov (Wash D C). 2017;2(2):55-65. doi: 10.1037/pri0000043. Epub 2017 Apr 3.


Coping strategies as mediators in relation to resilience and posttraumatic stress disorder.

Thompson NJ, Fiorillo D, Rothbaum BO, Ressler KJ, Michopoulos V.

J Affect Disord. 2018 Jan 1;225:153-159. doi: 10.1016/j.jad.2017.08.049. Epub 2017 Aug 16.


Using experimental methodologies to assess posttraumatic stress.

Jovanovic T, Rauch SA, Rothbaum AO, Rothbaum BO.

Curr Opin Psychol. 2017 Apr;14:23-28. doi: 10.1016/j.copsyc.2016.10.001. Epub 2016 Oct 19. Review.


Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder.

Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS.

Biol Psychiatry. 2017 Dec 15;82(12):866-874. doi: 10.1016/j.biopsych.2017.06.024. Epub 2017 Jul 4.


Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3,4-methylenedioxymethamphetamine (MDMA).

Young MB, Norrholm SD, Khoury LM, Jovanovic T, Rauch SAM, Reiff CM, Dunlop BW, Rothbaum BO, Howell LL.

Psychopharmacology (Berl). 2017 Oct;234(19):2883-2895. doi: 10.1007/s00213-017-4684-8. Epub 2017 Jul 24.


PTSD Psychotherapy Outcome Predicted by Brain Activation During Emotional Reactivity and Regulation.

Fonzo GA, Goodkind MS, Oathes DJ, Zaiko YV, Harvey M, Peng KK, Weiss ME, Thompson AL, Zack SE, Lindley SE, Arnow BA, Jo B, Gross JJ, Rothbaum BO, Etkin A.

Am J Psychiatry. 2017 Dec 1;174(12):1163-1174. doi: 10.1176/appi.ajp.2017.16091072. Epub 2017 Jul 18.


Selective Effects of Psychotherapy on Frontopolar Cortical Function in PTSD.

Fonzo GA, Goodkind MS, Oathes DJ, Zaiko YV, Harvey M, Peng KK, Weiss ME, Thompson AL, Zack SE, Mills-Finnerty CE, Rosenberg BM, Edelstein R, Wright RN, Kole CA, Lindley SE, Arnow BA, Jo B, Gross JJ, Rothbaum BO, Etkin A.

Am J Psychiatry. 2017 Dec 1;174(12):1175-1184. doi: 10.1176/appi.ajp.2017.16091073. Epub 2017 Jul 18.


Dexamethasone facilitates fear extinction and safety discrimination in PTSD: A placebo-controlled, double-blind study.

Michopoulos V, Norrholm SD, Stevens JS, Glover EM, Rothbaum BO, Gillespie CF, Schwartz AC, Ressler KJ, Jovanovic T.

Psychoneuroendocrinology. 2017 Sep;83:65-71. doi: 10.1016/j.psyneuen.2017.05.023. Epub 2017 May 31.


Virtual Reality-Enhanced Extinction of Phobias and Post-Traumatic Stress.

Maples-Keller JL, Yasinski C, Manjin N, Rothbaum BO.

Neurotherapeutics. 2017 Jul;14(3):554-563. doi: 10.1007/s13311-017-0534-y. Review.


Baroreflex dysfunction and augmented sympathetic nerve responses during mental stress in veterans with post-traumatic stress disorder.

Park J, Marvar PJ, Liao P, Kankam ML, Norrholm SD, Downey RM, McCullough SA, Le NA, Rothbaum BO.

J Physiol. 2017 Jul 15;595(14):4893-4908. doi: 10.1113/JP274269. Epub 2017 Jun 14.


The Use of Virtual Reality Technology in the Treatment of Anxiety and Other Psychiatric Disorders.

Maples-Keller JL, Bunnell BE, Kim SJ, Rothbaum BO.

Harv Rev Psychiatry. 2017 May/Jun;25(3):103-113. doi: 10.1097/HRP.0000000000000138. Review.


Targeting memory reconsolidation to prevent the return of fear in patients with fear of flying.

Maples-Keller JL, Price M, Jovanovic T, Norrholm SD, Odenat L, Post L, Zwiebach L, Breazeale K, Gross R, Kim SJ, Rothbaum BO.

Depress Anxiety. 2017 Jul;34(7):610-620. doi: 10.1002/da.22626. Epub 2017 Apr 5.


Investigating Relationships Between PTSD Symptom Clusters Within Virtual Reality Exposure Therapy for OEF/OIF Veterans.

Maples-Keller JL, Price M, Rauch S, Gerardi M, Rothbaum BO.

Behav Ther. 2017 Mar;48(2):147-155. doi: 10.1016/j.beth.2016.02.011. Epub 2016 Mar 4.


Mobile assessment of heightened skin conductance in posttraumatic stress disorder.

Hinrichs R, Michopoulos V, Winters S, Rothbaum AO, Rothbaum BO, Ressler KJ, Jovanovic T.

Depress Anxiety. 2017 Jun;34(6):502-507. doi: 10.1002/da.22610. Epub 2017 Feb 21.


D-Cycloserine Augmentation of Exposure-Based Cognitive Behavior Therapy for Anxiety, Obsessive-Compulsive, and Posttraumatic Stress Disorders: A Systematic Review and Meta-analysis of Individual Participant Data.

Mataix-Cols D, Fernández de la Cruz L, Monzani B, Rosenfield D, Andersson E, Pérez-Vigil A, Frumento P, de Kleine RA, Difede J, Dunlop BW, Farrell LJ, Geller D, Gerardi M, Guastella AJ, Hofmann SG, Hendriks GJ, Kushner MG, Lee FS, Lenze EJ, Levinson CA, McConnell H, Otto MW, Plag J, Pollack MH, Ressler KJ, Rodebaugh TL, Rothbaum BO, Scheeringa MS, Siewert-Siegmund A, Smits JAJ, Storch EA, Ströhle A, Tart CD, Tolin DF, van Minnen A, Waters AM, Weems CF, Wilhelm S, Wyka K, Davis M, Rück C; the DCS Anxiety Consortium, Altemus M, Anderson P, Cukor J, Finck C, Geffken GR, Golfels F, Goodman WK, Gutner C, Heyman I, Jovanovic T, Lewin AB, McNamara JP, Murphy TK, Norrholm S, Thuras P.

JAMA Psychiatry. 2017 May 1;74(5):501-510. doi: 10.1001/jamapsychiatry.2016.3955. Review. Erratum in: JAMA Psychiatry. 2017 May 1;74(5):542.


Amygdala Reactivity and Anterior Cingulate Habituation Predict Posttraumatic Stress Disorder Symptom Maintenance After Acute Civilian Trauma.

Stevens JS, Kim YJ, Galatzer-Levy IR, Reddy R, Ely TD, Nemeroff CB, Hudak LA, Jovanovic T, Rothbaum BO, Ressler KJ.

Biol Psychiatry. 2017 Jun 15;81(12):1023-1029. doi: 10.1016/j.biopsych.2016.11.015. Epub 2016 Dec 23.


Side Effects to Antidepressant Treatment in Patients With Depression and Comorbid Panic Disorder.

Shankman SA, Gorka SM, Katz AC, Klein DN, Markowitz JC, Arnow BA, Manber R, Rothbaum BO, Thase ME, Schatzberg AF, Keller MB, Trivedi MH, Kocsis JH.

J Clin Psychiatry. 2017 Apr;78(4):433-440. doi: 10.4088/JCP.15m10370.


Randomized controlled trial of prolonged exposure using imaginal exposure vs. virtual reality exposure in active duty soldiers with deployment-related posttraumatic stress disorder (PTSD).

Reger GM, Koenen-Woods P, Zetocha K, Smolenski DJ, Holloway KM, Rothbaum BO, Difede J, Rizzo AA, Edwards-Stewart A, Skopp NA, Mishkind M, Reger MA, Gahm GA.

J Consult Clin Psychol. 2016 Nov;84(11):946-959. doi: 10.1037/ccp0000134. Epub 2016 Sep 8.


Change in patients' interpersonal impacts as a mediator of the alliance-outcome association in treatment for chronic depression.

Constantino MJ, Laws HB, Coyne AE, Greenberg RP, Klein DN, Manber R, Rothbaum BO, Arnow BA.

J Consult Clin Psychol. 2016 Dec;84(12):1135-1144. Epub 2016 Oct 17.


Unintended Consequences of Changing the Definition of Posttraumatic Stress Disorder in DSM-5: Critique and Call for Action.

Hoge CW, Yehuda R, Castro CA, McFarlane AC, Vermetten E, Jetly R, Koenen KC, Greenberg N, Shalev AY, Rauch SA, Marmar CR, Rothbaum BO.

JAMA Psychiatry. 2016 Jul 1;73(7):750-2. doi: 10.1001/jamapsychiatry.2016.0647. No abstract available.


Treatment Options for Veterans With Posttraumatic Stress Disorder.

Rothbaum BO.

JAMA Psychiatry. 2016 Jul 1;73(7):756. doi: 10.1001/jamapsychiatry.2016.0563. No abstract available.


Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy.

Norrholm SD, Jovanovic T, Gerardi M, Breazeale KG, Price M, Davis M, Duncan E, Ressler KJ, Bradley B, Rizzo A, Tuerk PW, Rothbaum BO.

Behav Res Ther. 2016 Jul;82:28-37. doi: 10.1016/j.brat.2016.05.002. Epub 2016 May 7.

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