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Microsatellite instability and survival after adjuvant chemotherapy among stage II and III colon cancer patients: results from a population-based study.

Elizabeth A, Jansen L, Hendrik B, Kloor M, Tagscherer K, Roth W, Boakye D, Herpel E, Grüllich C, Chang-Claude J, Brenner H, Hoffmeister M.

Ann Oncol. 2019 Jul;30 Suppl 4:iv132. doi: 10.1093/annonc/mdz154.017. Epub 2019 Dec 4. No abstract available.


Do genetic ancestry tests increase racial essentialism? Findings from a randomized controlled trial.

Roth WD, Yaylacı Ş, Jaffe K, Richardson L.

PLoS One. 2020 Jan 29;15(1):e0227399. doi: 10.1371/journal.pone.0227399. eCollection 2020.


Postmenopausal hormone replacement therapy and colorectal cancer risk by molecular subtypes and pathways.

Amitay EL, Carr PR, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Int J Cancer. 2020 Jan 14. doi: 10.1002/ijc.32868. [Epub ahead of print]


Toward an Organic Theory for the Cultural-Historical Sciences.

Roth WM.

Integr Psychol Behav Sci. 2020 Jan 15. doi: 10.1007/s12124-019-09510-6. [Epub ahead of print]


[Variation in morphology or two entities?]

Gerber TS, Paschold M, Lang H, Roth W, Straub BK.

Pathologe. 2020 Feb;41(1):70-72. doi: 10.1007/s00292-019-00740-4. German.


Young-onset gastric cancer and Epstein-Barr Virus (EBV) - a major player in the pathogenesis?

Moore A, Hikri E, Goshen-Lago T, Barkan T, Morgenstern S, Brook E, Maderer A, Roth W, Gordon N, Kashtan H, Brenner B, Moehler M, Aharon IB.

BMC Cancer. 2020 Jan 14;20(1):34. doi: 10.1186/s12885-020-6517-0.


Association of BMI and major molecular pathological markers of colorectal cancer in men and women.

Carr PR, Amitay EL, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Schneider M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Am J Clin Nutr. 2020 Jan 3. pii: nqz315. doi: 10.1093/ajcn/nqz315. [Epub ahead of print]


Prognostic and Predictive Value of Tumor-infiltrating Leukocytes and of Immune Checkpoint Molecules PD1 and PDL1 in Clear Cell Renal Cell Carcinoma.

Stenzel PJ, Schindeldecker M, Tagscherer KE, Foersch S, Herpel E, Hohenfellner M, Hatiboglu G, Alt J, Thomas C, Haferkamp A, Roth W, Macher-Goeppinger S.

Transl Oncol. 2020 Feb;13(2):336-345. doi: 10.1016/j.tranon.2019.11.002. Epub 2019 Dec 24.


Microsatellite instability and survival after adjuvant chemotherapy among stage II and III colon cancer patients: results from a population-based study.

Alwers E, Jansen L, Bläker H, Kloor M, Tagscherer KE, Roth W, Boakye D, Herpel E, Grüllich C, Chang-Claude J, Brenner H, Hoffmeister M.

Mol Oncol. 2020 Feb;14(2):363-372. doi: 10.1002/1878-0261.12611. Epub 2020 Jan 7.


Randomized clinical trial of capnometry-assisted respiratory training in veterans with posttraumatic stress disorder hyperarousal.

Jamison AL, Slightam C, Bertram F, Kim S, Roth WT.

Psychol Trauma. 2019 Dec 5. doi: 10.1037/tra0000525. [Epub ahead of print]


[Liquid biopsy in colorectal cancer : An overview of ctDNA analysis in tumour diagnostics].

Haupts A, Roth W, Hartmann N.

Pathologe. 2019 Dec;40(Suppl 3):244-251. doi: 10.1007/s00292-019-00698-3. Review. German.


DNA methylation profiling to explore colorectal tumor differences according to menopausal hormone therapy use in women.

Neumeyer S, Popanda O, Butterbach K, Edelmann D, Bläker H, Toth C, Roth W, Herpel E, Jäkel C, Schmezer P, Benner A, Burwinkel B, Hoffmeister M, Brenner H, Chang-Claude J.

Epigenomics. 2019 Dec;11(16):1765-1778. doi: 10.2217/epi-2019-0051. Epub 2019 Nov 22.


Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer.

Martin SZ, Wagner DC, Hörner N, Horst D, Lang H, Tagscherer KE, Roth W.

BMC Cancer. 2019 Nov 1;19(1):1030. doi: 10.1186/s12885-019-6270-4.


Extended Molecular Profiling Improves Stratification and Prediction of Survival After Resection of Colorectal Liver Metastases.

Lang H, Baumgart J, Heinrich S, Tripke V, Passalaqua M, Maderer A, Galle PR, Roth W, Kloth M, Moehler M.

Ann Surg. 2019 Nov;270(5):799-805. doi: 10.1097/SLA.0000000000003527.


[Status of the availability and use of next generation sequencing (NGS) in bladder cancer-a questionnaire within the uropathology working group].

Ortiz-Brüchle N, Muders M, Toma M, Esposito I, Hartmann A, Stöhr R, Reis H, Wild P, Köllermann J, Bremmer F, Leichsenring J, Stenzinger A, Merkelbach-Bruse S, Kirfel S, Perner S, Hartmann N, Roth W, Jung A, Kirchner T, Schwamborn K, Pfarr N, Dahl E, Knüchel R, Gaisa NT.

Urologe A. 2019 Sep 20. doi: 10.1007/s00120-019-01046-2. [Epub ahead of print] Review. German.


Prediction of significant prostate cancer in biopsy-naïve men: Validation of a novel risk model combining MRI and clinical parameters and comparison to an ERSPC risk calculator and PI-RADS.

Radtke JP, Giganti F, Wiesenfarth M, Stabile A, Marenco J, Orczyk C, Kasivisvanathan V, Nyarangi-Dix JN, Schütz V, Dieffenbacher S, Görtz M, Stenzinger A, Roth W, Freeman A, Punwani S, Bonekamp D, Schlemmer HP, Hohenfellner M, Emberton M, Moore CM.

PLoS One. 2019 Aug 26;14(8):e0221350. doi: 10.1371/journal.pone.0221350. eCollection 2019.


ANKRD26-RET - A novel gene fusion involving RET in papillary thyroid carcinoma.

Staubitz JI, Musholt TJ, Schad A, Springer E, Lang H, Rajalingam K, Roth W, Hartmann N.

Cancer Genet. 2019 Oct;238:10-17. doi: 10.1016/j.cancergen.2019.07.002. Epub 2019 Jul 5.


Lamin-B1 is a senescence-associated biomarker in clear-cell renal cell carcinoma.

Radspieler MM, Schindeldecker M, Stenzel P, Försch S, Tagscherer KE, Herpel E, Hohenfellner M, Hatiboglu G, Roth W, Macher-Goeppinger S.

Oncol Lett. 2019 Sep;18(3):2654-2660. doi: 10.3892/ol.2019.10593. Epub 2019 Jul 9.


A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival.

Jia M, Zhang Y, Jansen L, Walter V, Edelmann D, Gündert M, Tagscherer KE, Roth W, Bewerunge-Hudler M, Herpel E, Kloor M, Ulrich A, Burwinkel B, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

Clin Epigenetics. 2019 Jul 24;11(1):109. doi: 10.1186/s13148-019-0703-4.


External validation of molecular subtype classifications of colorectal cancer based on microsatellite instability, CIMP, BRAF and KRAS.

Alwers E, Bläker H, Walter V, Jansen L, Kloor M, Arnold A, Sieber-Frank J, Herpel E, Tagscherer KE, Roth W, Chang-Claude J, Brenner H, Hoffmeister M.

BMC Cancer. 2019 Jul 11;19(1):681. doi: 10.1186/s12885-019-5842-7.


In Vitro Entero-Capillary Barrier Exhibits Altered Inflammatory and Exosomal Communication Pattern after Exposure to Silica Nanoparticles.

Kasper JY, Hermanns MI, Kraegeloh A, Roth W, Kirkpatrick CJ, Unger RE.

Int J Mol Sci. 2019 Jul 5;20(13). pii: E3301. doi: 10.3390/ijms20133301.


History and Future of Nucleic Acid Amplification Technology Blood Donor Testing.

Roth WK.

Transfus Med Hemother. 2019 Apr;46(2):67-75. doi: 10.1159/000496749. Epub 2019 Feb 5. Review.


PD-L1 Expression and Immune Cell Infiltration in Gastroenteropancreatic (GEP) and Non-GEP Neuroendocrine Neoplasms With High Proliferative Activity.

Ferrata M, Schad A, Zimmer S, Musholt TJ, Bahr K, Kuenzel J, Becker S, Springer E, Roth W, Weber MM, Fottner C.

Front Oncol. 2019 May 7;9:343. doi: 10.3389/fonc.2019.00343. eCollection 2019.


Perilipin 1 Expression Differentiates Liposarcoma from Other Types of Soft Tissue Sarcoma.

Straub BK, Witzel HR, Pawella LM, Renner M, Eiteneuer E, Hashani M, Schirmacher P, Roth W, Mechtersheimer G.

Am J Pathol. 2019 Aug;189(8):1547-1558. doi: 10.1016/j.ajpath.2019.04.017. Epub 2019 May 22.


Effects of psychosocial and physical stress on lactate and anxiety levels.

Hermann R, Lay D, Wahl P, Roth WT, Petrowski K.

Stress. 2019 Nov;22(6):664-669. doi: 10.1080/10253890.2019.1610743. Epub 2019 May 7.


[Lymphadenectomy in oncological visceral surgery-Part 1 : Hepatobiliary tumors and pancreatic cancer].

Bartsch F, Heinrich S, Roth W, Lang H.

Chirurg. 2019 May;90(5):423-438. doi: 10.1007/s00104-019-0956-7. Review. German.


Relationship between EGFR expression and subcellular localization with cancer development and clinical outcome.

Yan G, Saeed MEM, Foersch S, Schneider J, Roth W, Efferth T.

Oncotarget. 2019 Mar 8;10(20):1918-1931. doi: 10.18632/oncotarget.26727. eCollection 2019 Mar 8.


Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer.

Neumeyer S, Popanda O, Edelmann D, Butterbach K, Toth C, Roth W, Bläker H, Jiang R, Herpel E, Jäkel C, Schmezer P, Jansen L, Alwers E, Benner A, Burwinkel B, Hoffmeister M, Brenner H, Chang-Claude J.

Epigenetics. 2019 May;14(5):477-493. doi: 10.1080/15592294.2019.1595998. Epub 2019 Mar 30.


Consensus Guidelines on the Use of Superficial Radiation Therapy for Treating Nonmelanoma Skin Cancers and Keloids.

Nestor MS, Berman B, Goldberg D, Cognetta AB Jr, Gold M, Roth W, Cockerell CJ, Glick B.

J Clin Aesthet Dermatol. 2019 Feb;12(2):12-18. Epub 2019 Feb 1.


Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma.

Quaas A, Heydt C, Waldschmidt D, Alakus H, Zander T, Goeser T, Kasper P, Bruns C, Brunn A, Roth W, Hartmann N, Bunck A, Schmidt M, Buettner R, Merkelbach-Bruse S.

BMC Gastroenterol. 2019 Feb 4;19(1):21. doi: 10.1186/s12876-019-0942-z.


DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells.

Even I, Reidenbach S, Schlechter T, Berns N, Herold R, Roth W, Krunic D, Riechmann V, Hofmann I.

FEBS J. 2019 Feb;286(4):803-820. doi: 10.1111/febs.14755. Epub 2019 Feb 7.


[Hepatocellular carcinoma in an inflammatory adenoma with β-catenin mutation in a patient with hepatocellular adenomatosis due to germline mutation in HNF1α].

Ridder DA, Duret D, Wörns MA, Schotten S, Heinrich S, Kloth M, Springer E, Roth W, Straub BK.

Z Gastroenterol. 2019 Jan;57(1):46-51. doi: 10.1055/a-0821-7154. Epub 2019 Jan 14. German.


Bayesian Neural Networks with Weight Sharing Using Dirichlet Processes.

Roth W, Pernkopf F.

IEEE Trans Pattern Anal Mach Intell. 2020 Jan;42(1):246-252. doi: 10.1109/TPAMI.2018.2884905. Epub 2018 Dec 6.


The ASAMET trial: a randomized, phase II, double-blind, placebo-controlled, multicenter, 2 × 2 factorial biomarker study of tertiary prevention with low-dose aspirin and metformin in stage I-III colorectal cancer patients.

Petrera M, Paleari L, Clavarezza M, Puntoni M, Caviglia S, Briata IM, Oppezzi M, Mislej EM, Stabuc B, Gnant M, Bachleitner-Hofmann T, Roth W, Scherer D, Haefeli WE, Ulrich CM, DeCensi A.

BMC Cancer. 2018 Dec 4;18(1):1210. doi: 10.1186/s12885-018-5126-7.


Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification.

Castven D, Becker D, Czauderna C, Wilhelm D, Andersen JB, Strand S, Hartmann M, Heilmann-Heimbach S, Roth W, Hartmann N, Straub BK, Mahn FL, Franck S, Pereira S, Haupts A, Vogel A, Wörns MA, Weinmann A, Heinrich S, Lang H, Thorgeirsson SS, Galle PR, Marquardt JU.

Int J Cancer. 2019 Jun 1;144(11):2782-2794. doi: 10.1002/ijc.32026. Epub 2018 Dec 14.


Combined Clinical Parameters and Multiparametric Magnetic Resonance Imaging for the Prediction of Extraprostatic Disease-A Risk Model for Patient-tailored Risk Stratification When Planning Radical Prostatectomy.

Nyarangi-Dix J, Wiesenfarth M, Bonekamp D, Hitthaler B, Schütz V, Dieffenbacher S, Mueller-Wolf M, Roth W, Stenzinger A, Duensing S, Roethke M, Teber D, Schlemmer HP, Hohenfellner M, Radtke JP.

Eur Urol Focus. 2018 Nov 23. pii: S2405-4569(18)30336-5. doi: 10.1016/j.euf.2018.11.004. [Epub ahead of print]


Novel rearrangements involving the RET gene in papillary thyroid carcinoma.

Staubitz JI, Schad A, Springer E, Rajalingam K, Lang H, Roth W, Hartmann N, Musholt TJ.

Cancer Genet. 2019 Jan;230:13-20. doi: 10.1016/j.cancergen.2018.11.002. Epub 2018 Nov 13.


Correlation between genomic index lesions and mpMRI and 68Ga-PSMA-PET/CT imaging features in primary prostate cancer.

Kesch C, Radtke JP, Wintsche A, Wiesenfarth M, Luttje M, Gasch C, Dieffenbacher S, Pecqueux C, Teber D, Hatiboglu G, Nyarangi-Dix J, Simpfendörfer T, Schönberg G, Dimitrakopoulou-Strauss A, Freitag M, Duensing A, Grüllich C, Jäger D, Götz M, Grabe N, Schweiger MR, Pahernik S, Perner S, Herpel E, Roth W, Wieczorek K, Maier-Hein K, Debus J, Haberkorn U, Giesel F, Galle J, Hadaschik B, Schlemmer HP, Hohenfellner M, Bonekamp D, Sültmann H, Duensing S.

Sci Rep. 2018 Nov 12;8(1):16708. doi: 10.1038/s41598-018-35058-3.


Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes.

Amitay EL, Carr PR, Jansen L, Walter V, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.

J Natl Cancer Inst. 2019 May 1;111(5):475-483. doi: 10.1093/jnci/djy170.


[Digital pathology in immuno-oncology-current opportunities and challenges : Overview of the analysis of immune cell infiltrates using whole slide imaging].

Grabe N, Roth W, Foersch S.

Pathologe. 2018 Nov;39(6):539-545. doi: 10.1007/s00292-018-0540-9. Review. German.


[Prognostic significance of immune cell infiltrates in tumor pathology].

Wagner DC, Roth W.

Pathologe. 2018 Nov;39(6):532-538. doi: 10.1007/s00292-018-0541-8. Review. German.



Roth W.

Pathologe. 2018 Nov;39(6):491. doi: 10.1007/s00292-018-0533-8. German. No abstract available.


Early myoclonus following anoxic brain injury.

Reynolds AS, Rohaut B, Holmes MG, Robinson D, Roth W, Velazquez A, Couch CK, Presciutti A, Brodie D, Moitra VK, Rabbani LE, Agarwal S, Park S, Roh DJ, Claassen J.

Neurol Clin Pract. 2018 Jun;8(3):249-256. doi: 10.1212/CPJ.0000000000000466. Review.


Motivation to Participate in PTSD Research.

Roth WT, Hofmann SG.

JAMA. 2018 Jun 19;319(23):2439-2440. doi: 10.1001/jama.2018.4326. No abstract available.


Distinct Activities of Glycolytic Enzymes Identify Chronic Lymphocytic Leukemia Patients with a more Aggressive Course and Resistance to Chemo-Immunotherapy.

Gdynia G, Robak T, Kopitz J, Heller A, Grekova S, Duglova K, Laukemper G, Heinzel-Gutenbrunner M, Gutenbrunner C, Roth W, Ho AD, Schirmacher P, Schmitt M, Dreger P, Sellner L.

EBioMedicine. 2018 Jun;32:125-133. doi: 10.1016/j.ebiom.2018.05.030. Epub 2018 Jun 5.


Therapy susceptible germline-related BRCA 1-mutation in a case of metastasized mixed adeno-neuroendocrine carcinoma (MANEC) of the small bowel.

Quaas A, Waldschmidt D, Alakus H, Zander T, Heydt C, Goeser T, Daheim M, Kasper P, Plum P, Bruns C, Brunn A, Roth W, Hartmann N, Bunck A, Schmidt M, Göbel H, Tharun L, Buettner R, Merkelbach-Bruse S.

BMC Gastroenterol. 2018 May 31;18(1):75. doi: 10.1186/s12876-018-0803-1.


Iron-Based Metal-Organic Frameworks as a Theranostic Carrier for Local Tuberculosis Therapy.

Wyszogrodzka G, Dorożyński P, Gil B, Roth WJ, Strzempek M, Marszałek B, Węglarz WP, Menaszek E, Strzempek W, Kulinowski P.

Pharm Res. 2018 May 18;35(7):144. doi: 10.1007/s11095-018-2425-2.


Particles of vaterite, a metastable CaCO3 polymorph, exhibit high biocompatibility for human osteoblasts and endothelial cells and may serve as a biomaterial for rapid bone regeneration.

Schröder R, Besch L, Pohlit H, Panthöfer M, Roth W, Frey H, Tremel W, Unger RE.

J Tissue Eng Regen Med. 2018 Jul;12(7):1754-1768. doi: 10.1002/term.2703. Epub 2018 Jun 10.


Widespread expression of perilipin 5 in normal human tissues and in diseases is restricted to distinct lipid droplet subpopulations.

Hashani M, Witzel HR, Pawella LM, Lehmann-Koch J, Schumacher J, Mechtersheimer G, Schnölzer M, Schirmacher P, Roth W, Straub BK.

Cell Tissue Res. 2018 Oct;374(1):121-136. doi: 10.1007/s00441-018-2845-7. Epub 2018 May 11.


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