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High mutational concordance between primary colorectal tumors and associated pulmonary metastases.

Corsini EM, Datar SS, Mitchell KG, Zhou N, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Blackmon SH, Loree JM, Morris VK, Antonoff MB.

J Surg Oncol. 2020 Feb 19. doi: 10.1002/jso.25871. [Epub ahead of print]


Clinical activity of programmed cell death 1 (PD-1) blockade in never, light, and heavy smokers with non-small-cell lung cancer and PD-L1 expression ≥50.

Gainor JF, Rizvi H, Jimenez Aguilar E, Skoulidis F, Yeap BY, Naidoo J, Khosrowjerdi S, Mooradian M, Lydon C, Illei P, Zhang J, Peterson R, Ricciuti B, Nishino M, Zhang J, Roth JA, Grishman J, Anderson D, Little BP, Carter BW, Arbour K, Sauter JL, Mino-Kenudson M, Heymach JV, Digumarthy S, Shaw AT, Awad MM, Hellmann MD.

Ann Oncol. 2020 Mar;31(3):404-411. doi: 10.1016/j.annonc.2019.11.015. Epub 2019 Dec 9.


Repeated Syphilis Episodes in HIV-Infected Men Who Have Sex With Men: A Multicenter Prospective Cohort Study on Risk Factors and the Potential Role of Syphilis Immunity.

Roth JA, Franzeck FC, Balakrishna S, Lautenschlager S, Thurnheer MC, Trellu LT, Cavassini M, Vernazza P, Bernasconi E, Braun D, Kouyos RD, Battegay M; Swiss HIV Cohort Study (SHCS) .

Open Forum Infect Dis. 2020 Jan 12;7(1):ofaa019. doi: 10.1093/ofid/ofaa019. eCollection 2020 Jan.


Clinical and Budget Impact of Increasing Colorectal Cancer Screening by Blood- and Stool-Based Testing.

Roth JA, deVos T, Ramsey SD.

Am Health Drug Benefits. 2019 Sep;12(5):256-262.


Surveillance After Treatment of Non-Small-Cell Lung Cancer: A Call for Multidisciplinary Standardization.

Mitchell KG, Nelson DB, Corsini EM, Correa AM, Erasmus JJ, Hofstetter WL, Mehran RJ, Roth JA, Swisher SG, Sepesi B, Walsh GL, Vaporciyan AA, Rice DC, Nguyen QN, Antonoff MB.

Innovations (Phila). 2019 Dec 26:1556984519886281. doi: 10.1177/1556984519886281. [Epub ahead of print]


Preoperative Heparin for Lung Cancer Resection Increases Risk of Reoperation for Bleeding.

Van Haren RM, Rajaram R, Correa AM, Mehran RJ, Antonoff MB, Hofstetter WL, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC, Roth JA.

Semin Thorac Cardiovasc Surg. 2019 Dec 17. pii: S1043-0679(19)30384-3. doi: 10.1053/j.semtcvs.2019.12.001. [Epub ahead of print]


From clinical specimens to human cancer preclinical models-a journey the NCI-cell line database-25 years later.

Mulshine JL, Ujhazy P, Antman M, Burgess CM, Kuzmin I, Bunn PA Jr, Johnson BE, Roth JA, Pass HI, Ross SM, Aldige CR, Wistuba II, Minna JD.

J Cell Biochem. 2019 Dec 5. doi: 10.1002/jcb.29564. [Epub ahead of print]


The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma.

Zhuo M, Guan Y, Yang X, Hong L, Wang Y, Li Z, Chen R, Abbas H, Chang L, Gong Y, Wu N, Zhong J, Chen W, Chen H, Dong Z, Zhu X, Li J, Wang Y, An T, Wu M, Wang Z, Wang J, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG, Lee JJ, Heymach JV, Wistuba II, Kalhor N, Yang L, Yi X, Futreal PA, Glisson BS, Xia X, Zhang J, Zhao J.

Clin Cancer Res. 2020 Feb 15;26(4):892-901. doi: 10.1158/1078-0432.CCR-19-0556. Epub 2019 Nov 6.


Safety and Costs of Endobronchial Ultrasound-Guided Nodal Aspiration and Mediastinoscopy.

Verdial FC, Berfield KS, Wood DE, Mulligan MS, Roth JA, Francis DO, Farjah F.

Chest. 2019 Oct 9. pii: S0012-3692(19)34002-4. doi: 10.1016/j.chest.2019.09.021. [Epub ahead of print]


High incidence of urinary tract infections after photoselective laser vaporisation of the prostate: a risk factor analysis of 665 patients.

Bausch K, Motzer J, Roth JA, Dangel M, Seifert HH, Widmer AF.

World J Urol. 2019 Oct 1. doi: 10.1007/s00345-019-02969-3. [Epub ahead of print]


Contribution of specific pathogens to bloodstream infection mortality in neutropenic patients with hematologic malignancies: Results from a multicentric surveillance cohort study.

Kern WV, Roth JA, Bertz H, Götting T, Dettenkofer M, Widmer AF, Theilacker C; Hospital Infection Surveillance System for Patients with Hematologic/Oncologic Malignancies Study Group (ONKO-KISS).

Transpl Infect Dis. 2019 Dec;21(6):e13186. doi: 10.1111/tid.13186. Epub 2019 Nov 1.


Intensity modulated radiation therapy following lumpectomy in early-stage breast cancer: Patterns of use and cost consequences among Medicare beneficiaries.

Halasz LM, Patel SA, McDougall JA, Fedorenko C, Sun Q, Goulart BHL, Roth JA.

PLoS One. 2019 Sep 30;14(9):e0222904. doi: 10.1371/journal.pone.0222904. eCollection 2019.


Multidisciplinary treatment of thymic neuroendocrine tumors: surgery remains a key component.

Corsini EM, Mitchell KG, Sceusi EL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Swisher SG, Roth JA, Vaporciyan AA, Hofstetter WL, Antonoff MB.

J Thorac Dis. 2019 Aug;11(8):3391-3398. doi: 10.21037/jtd.2019.08.20.


Cost-Effectiveness Analysis of Adjuvant Neratinib Following Trastuzumab in Early-Stage HER2-Positive Breast Cancer.

Schwartz NRM, Flanagan MR, Babigumira JB, Steuten LM, Roth JA.

J Manag Care Spec Pharm. 2019 Oct;25(10):1133-1139. doi: 10.18553/jmcp.2019.25.10.1133.


Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.

Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, Samuel CE, Lin SH, Kabil NN, Wang J, Majidi M, Fang B, Roth JA, Vaporciyan AA, Wistuba II, Hung MC, Swisher SG.

Oncogene. 2020 Jan;39(4):801-813. doi: 10.1038/s41388-019-1010-4. Epub 2019 Sep 25.


Reply to Yoshioka et al.

Roth JA, Widmer AF.

Clin Infect Dis. 2019 Aug 12. pii: ciz751. doi: 10.1093/cid/ciz751. [Epub ahead of print] No abstract available.


Morbidity following salvage esophagectomy for squamous cell carcinoma: the MD Anderson experience.

Mitchell KG, Nelson DB, Corsini EM, Vaporciyan AA, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Sepesi B, Walsh GL, Bhutani MS, Maru DM, Wu CC, Nguyen QN, Ajani JA, Swisher SG, Hofstetter WL.

Dis Esophagus. 2019 Jul 17. pii: doz067. doi: 10.1093/dote/doz067. [Epub ahead of print]


Impact of health insurance status on surgical site infection incidence: A prospective cohort study.

Duggan BT, Roth JA, Dangel M, Battegay M, Widmer AF.

Infect Control Hosp Epidemiol. 2019 Sep;40(9):1063-1065. doi: 10.1017/ice.2019.195. Epub 2019 Jul 16.


Colorectal cancer mutations are associated with survival and recurrence after pulmonary metastasectomy.

Corsini EM, Mitchell KG, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Swisher SG, Roth JA, Hofstetter WL, Vaporciyan AA, Morris VK, Antonoff MB.

J Surg Oncol. 2019 Sep;120(4):729-735. doi: 10.1002/jso.25630. Epub 2019 Jul 9.


Tumor characteristics associated with engraftment of patient-derived non-small cell lung cancer xenografts in immunocompromised mice.

Chen Y, Zhang R, Wang L, Correa AM, Pataer A, Xu Y, Zhang X, Ren C, Wu S, Meng QH, Fujimoto J, Jensen VB, Antonoff MB, Hofstetter WL, Mehran RJ, Pisimisis G, Rice DC, Sepesi B, Vaporciyan AA, Walsh GL, Swisher SG, Roth JA, Heymach JV, Fang B.

Cancer. 2019 Nov 1;125(21):3738-3748. doi: 10.1002/cncr.32366. Epub 2019 Jul 9.


Glutathione reductase (GSR) gene deletion and chromosome 8 aneuploidy in primary lung cancers detected by fluorescence in situ hybridization.

Baity M, Wang L, Correa AM, Zhang X, Zhang R, Pataer A, Wu S, Meng QH, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Zhao M, Gu J, Fang B.

Am J Cancer Res. 2019 Jun 1;9(6):1201-1211. eCollection 2019.


Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer.

Mitchell KG, Parra ER, Nelson DB, Zhang J, Wistuba II, Fujimoto J, Roth JA, Antonoff MB; MD Anderson Lung Cancer Immune Microenvironment Working Group.

J Thorac Cardiovasc Surg. 2019 Sep;158(3):911-919.e6. doi: 10.1016/j.jtcvs.2019.04.084. Epub 2019 May 17.


Early versus late onset bloodstream infection during neutropenia after high-dose chemotherapy for hematologic malignancy.

Widmer AF, Kern WV, Roth JA, Dettenkofer M, Goetting T, Bertz H, Theilacker C; Hospital Infection Surveillance System for Patients with Hematologic/Oncologic Malignancies Study Group (ONKO-KISS).

Infection. 2019 Oct;47(5):837-845. doi: 10.1007/s15010-019-01327-0. Epub 2019 Jun 11.


An Improved Patient-Derived Xenograft Humanized Mouse Model for Evaluation of Lung Cancer Immune Responses.

Meraz IM, Majidi M, Meng F, Shao R, Ha MJ, Neri S, Fang B, Lin SH, Tinkey PT, Shpall EJ, Morris J, Roth JA.

Cancer Immunol Res. 2019 Aug;7(8):1267-1279. doi: 10.1158/2326-6066.CIR-18-0874. Epub 2019 Jun 11.


Defining the role of adjuvant radiotherapy for malignant pleural mesothelioma: a propensity-matched landmark analysis of the National Cancer Database.

Nelson DB, Rice DC, Mitchell KG, Tsao AS, Vaporciyan AA, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Gomez DR, Mehran RJ, Sepesi B.

J Thorac Dis. 2019 Apr;11(4):1269-1278. doi: 10.21037/jtd.2019.04.27.


Mediastinal Nodal Involvement After Neoadjuvant Chemoradiation for Siewert II/III Adenocarcinoma.

Mitchell KG, Ikoma N, Nelson DB, Maru DM, Erasmus JJ, Weston BR, Vaporciyan AA, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Swisher SG, Sepesi B, Walsh GL, Correa AM, Das P, Blum MA, Badgwell BD, Hofstetter WL.

Ann Thorac Surg. 2019 Sep;108(3):845-851. doi: 10.1016/j.athoracsur.2019.04.024. Epub 2019 May 15.


Robotic-Assisted Lobectomy for Non-Small Cell Lung Cancer: A Comprehensive Institutional Experience.

Nelson DB, Mehran RJ, Mitchell KG, Rajaram R, Correa AM, Bassett RL Jr, Antonoff MB, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Walsh GL, Vaporciyan AA, Rice DC.

Ann Thorac Surg. 2019 Aug;108(2):370-376. doi: 10.1016/j.athoracsur.2019.03.051. Epub 2019 Apr 18.


Should endoscopic mucosal resection be attempted for cT2N0 esophageal cancer?

Nelson DB, Mitchell KG, Weston BR, Betancourt S, Maru D, Rice DC, Mehran RJ, Sepesi B, Antonoff MB, Walsh GL, Swisher SG, Roth JA, Vaporciyan AA, Blum M, Hofstetter WL.

Dis Esophagus. 2019 Dec 13;32(10):1-6. doi: 10.1093/dote/doz016.


Single-dose versus 3-day cotrimoxazole prophylaxis in transurethral resection or greenlight laser vaporisation of the prostate: study protocol for a multicentre randomised placebo controlled non-inferiority trial (CITrUS trial).

Speich B, Bausch K, Roth JA, Hemkens LG, Ewald H, Vogt DR, Bruni N, Deuster S, Seifert HH, Widmer AF.

Trials. 2019 Feb 19;20(1):142. doi: 10.1186/s13063-019-3237-3.


PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer.

Negrao MV, Lam VK, Reuben A, Rubin ML, Landry LL, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG, Gibbons DL, Wistuba II, Papadimitrakopoulou V, Glisson BS, Blumenschein GR Jr, Lee JJ, Heymach JV, Zhang J.

J Thorac Oncol. 2019 Jun;14(6):1021-1031. doi: 10.1016/j.jtho.2019.02.008. Epub 2019 Feb 16.


Occult stage IIIA-N2 patients have excellent overall survival with initial surgery.

Kim MP, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Erasmus JJ, Swisher SG.

J Thorac Dis. 2018 Dec;10(12):6670-6676. doi: 10.21037/jtd.2018.10.94.


Medical diagnoses showed low relatedness in an explorative mutual information analysis of 190,837 inpatient cases.

Roth JA, Sakoparnig T, Neubauer S, Kuenzel-Pawlik E, Gerber M, Widmer AF, Hug BL; PATREC Study Group.

J Clin Epidemiol. 2019 May;109:42-50. doi: 10.1016/j.jclinepi.2019.01.003. Epub 2019 Jan 11.


Surgical margins and risk of local recurrence after wedge resection of colorectal pulmonary metastases.

Nelson DB, Tayob N, Mitchell KG, Correa AM, Hofstetter WL, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Antonoff MB, Roth JA, Rice DC, Vauthey JN, Mehran RJ.

J Thorac Cardiovasc Surg. 2019 Apr;157(4):1648-1655. doi: 10.1016/j.jtcvs.2018.10.156. Epub 2018 Nov 26.


Ground Glass Lesions on Chest Imaging: Evaluation of Reported Incidence in Cancer Patients Using Natural Language Processing.

Van Haren RM, Correa AM, Sepesi B, Rice DC, Hofstetter WL, Mehran RJ, Vaporciyan AA, Walsh GL, Roth JA, Swisher SG, Antonoff MB.

Ann Thorac Surg. 2019 Mar;107(3):936-940. doi: 10.1016/j.athoracsur.2018.09.016. Epub 2018 Oct 26.


Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer.

Pu X, Zhang R, Wang L, Chen Y, Xu Y, Pataer A, Meraz IM, Zhang X, Wu S, Wu L, Su D, Mao W, Heymach JV, Roth JA, Swisher SG, Fang B.

J Transl Med. 2018 Nov 26;16(1):328. doi: 10.1186/s12967-018-1704-3.


A 5-microRNA signature identified from serum microRNA profiling predicts survival in patients with advanced stage non-small cell lung cancer.

Zhang Y, Roth JA, Yu H, Ye Y, Xie K, Zhao H, Chang DW, Huang M, Li H, Qu J, Wu X.

Carcinogenesis. 2019 Jul 4;40(5):643-650. doi: 10.1093/carcin/bgy132.


Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis.

Yan X, Zhang X, Wang L, Zhang R, Pu X, Wu S, Li L, Tong P, Wang J, Meng QH, Jensen VB, Girard L, Minna JD, Roth JA, Swisher SG, Heymach JV, Fang B.

Cancer Res. 2019 Jan 1;79(1):125-132. doi: 10.1158/0008-5472.CAN-18-1938. Epub 2018 Nov 6.


Introduction to Machine Learning in Digital Healthcare Epidemiology.

Roth JA, Battegay M, Juchler F, Vogt JE, Widmer AF.

Infect Control Hosp Epidemiol. 2018 Dec;39(12):1457-1462. doi: 10.1017/ice.2018.265. Epub 2018 Nov 5. Review.


Local Consolidation Therapy (LCT) After First Line Tyrosine Kinase Inhibitor (TKI) for Patients With EGFR Mutant Metastatic Non-small-cell Lung Cancer (NSCLC).

Elamin YY, Gomez DR, Antonoff MB, Robichaux JP, Tran H, Shorter MK, Bohac JM, Negrao MV, Le X, Rinsurogkawong W, Lewis J, Lacerda L, Roarty EB, Swisher SG, Roth JA, Zhang J, Papadimitrakopoulou V, Heymach JV.

Clin Lung Cancer. 2019 Jan;20(1):43-47. doi: 10.1016/j.cllc.2018.09.015. Epub 2018 Sep 24.


Frequent Door Openings During Cardiac Surgery Are Associated With Increased Risk for Surgical Site Infection: A Prospective Observational Study.

Roth JA, Juchler F, Dangel M, Eckstein FS, Battegay M, Widmer AF.

Clin Infect Dis. 2019 Jul 2;69(2):290-294. doi: 10.1093/cid/ciy879.


Validation of the 12-gene Predictive Signature for Adjuvant Chemotherapy Response in Lung Cancer.

Xie Y, Lu W, Wang S, Tang X, Tang H, Zhou Y, Moran C, Behrens C, Roth JA, Zhou Q, Johnson DH, Swisher SG, Heymach JV, Papadimitrakopoulou VA, Xiao G, Minna JD, Wistuba II.

Clin Cancer Res. 2019 Jan 1;25(1):150-157. doi: 10.1158/1078-0432.CCR-17-2543. Epub 2018 Oct 4.


Cost-effectiveness of axicabtagene ciloleucel for adult patients with relapsed or refractory large B-cell lymphoma in the United States.

Roth JA, Sullivan SD, Lin VW, Bansal A, Purdum AG, Navale L, Cheng P, Ramsey SD.

J Med Econ. 2018 Dec;21(12):1238-1245. doi: 10.1080/13696998.2018.1529674. Epub 2018 Oct 16. Erratum in: J Med Econ. 2018 Dec;21(12):1255.


Comment on "The domestic cat antibody responseto FHV-1 increases with age".

Roth JA.

Vet Immunol Immunopathol. 2018 Sep;203:65. doi: 10.1016/j.vetimm.2018.08.007. Epub 2018 Aug 20. No abstract available.


Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC.

Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, Hicks JK, Lovinger KL, Roarty E, Rinsurongkawong W, Tang M, Sun H, Elamin Y, Lacerda LC, Lewis J, Roth JA, Swisher SG, Lee JJ, William WN Jr, Glisson BS, Zhang J, Papadimitrakopoulou VA, Gray JE, Heymach JV.

Clin Cancer Res. 2018 Dec 15;24(24):6195-6203. doi: 10.1158/1078-0432.CCR-18-1542. Epub 2018 Sep 18.


Secondary use of routine data in hospitals: description of a scalable analytical platform based on a business intelligence system.

Roth JA, Goebel N, Sakoparnig T, Neubauer S, Kuenzel-Pawlik E, Gerber M, Widmer AF, Abshagen C, Padiyath R, Hug BL; PATREC Study Group .

JAMIA Open. 2018 Sep 20;1(2):172-177. doi: 10.1093/jamiaopen/ooy039. eCollection 2018 Oct.


Plea for Standardized Reporting and Justification of Propensity Score Methods.

Roth JA, Juchler F, Widmer AF, Battegay M.

Clin Infect Dis. 2019 Feb 1;68(4):710-711. doi: 10.1093/cid/ciy700. No abstract available.


Costs versus earnings in colon surgery and coronary artery bypass grafting under a prospective payment system: Sufficient financial incentives to reduce surgical site infections?

Juchler F, Roth JA, Schweiger A, Dangel M, Gugliotta M, Battegay M, Eckstein FS, Kettelhack C, Abshagen C, Hug BL, Boyce JM, Widmer AF.

Infect Control Hosp Epidemiol. 2018 Oct;39(10):1246-1249. doi: 10.1017/ice.2018.179. Epub 2018 Aug 22.


Perioperative Outcomes for Stage I Non-Small Cell Lung Cancer: Differences Between Men and Women.

Nelson DB, Lapid DJ, Mitchell KG, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Antonoff MB.

Ann Thorac Surg. 2018 Nov;106(5):1499-1503. doi: 10.1016/j.athoracsur.2018.06.070. Epub 2018 Aug 15.


Predictors of survival after resection of primary sarcomas of the chest wall-A large, single-institution series.

Shewale JB, Mitchell KG, Nelson DB, Conley AP, Rice DC, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Mehran RJ, Vaporciyan AA, Weissferdt A, Sepesi B.

J Surg Oncol. 2018 Sep;118(3):518-524. doi: 10.1002/jso.25162. Epub 2018 Aug 15.


A qualitative study exploring patient motivations for screening for lung cancer.

Roth JA, Carter-Harris L, Brandzel S, Buist DSM, Wernli KJ.

PLoS One. 2018 Jul 5;13(7):e0196758. doi: 10.1371/journal.pone.0196758. eCollection 2018.

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