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Items: 1 to 50 of 672

1.

Denitrification Aligns with N2 Fixation in Red Sea Corals.

Tilstra A, El-Khaled YC, Roth F, Rädecker N, Pogoreutz C, Voolstra CR, Wild C.

Sci Rep. 2019 Dec 19;9(1):19460. doi: 10.1038/s41598-019-55408-z.

2.

MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect.

Esposito D, Weile J, Shendure J, Starita LM, Papenfuss AT, Roth FP, Fowler DM, Rubin AF.

Genome Biol. 2019 Nov 4;20(1):223. doi: 10.1186/s13059-019-1845-6.

3.

Highly Combinatorial Genetic Interaction Analysis Reveals a Multi-Drug Transporter Influence Network.

Celaj A, Gebbia M, Musa L, Cote AG, Snider J, Wong V, Ko M, Fong T, Bansal P, Mellor JC, Seesankar G, Nguyen M, Zhou S, Wang L, Kishore N, Stagljar I, Suzuki Y, Yachie N, Roth FP.

Cell Syst. 2019 Oct 14. pii: S2405-4712(19)30317-5. doi: 10.1016/j.cels.2019.09.009. [Epub ahead of print]

4.

Extreme biomimetics: Preservation of molecular detail in centimeter-scale samples of biological meshes laid down by sponges.

Petrenko I, Summers AP, Simon P, Żółtowska-Aksamitowska S, Motylenko M, Schimpf C, Rafaja D, Roth F, Kummer K, Brendler E, Pokrovsky OS, Galli R, Wysokowski M, Meissner H, Niederschlag E, Joseph Y, Molodtsov S, Ereskovsky A, Sivkov V, Nekipelov S, Petrova O, Volkova O, Bertau M, Kraft M, Rogalev A, Kopani M, Jesioniowski T, Ehrlich H.

Sci Adv. 2019 Oct 4;5(10):eaax2805. doi: 10.1126/sciadv.aax2805. eCollection 2019 Oct.

5.

Multiple stressor effects on coral reef ecosystems.

Ellis JI, Jamil T, Anlauf H, Coker DJ, Curdia J, Hewitt J, Jones BH, Krokos G, Kürten B, Hariprasad D, Roth F, Carvalho S, Hoteit I.

Glob Chang Biol. 2019 Dec;25(12):4131-4146. doi: 10.1111/gcb.14819. Epub 2019 Oct 9.

PMID:
31482629
6.

Quantifying immune-based counterselection of somatic mutations.

Yang F, Kim DK, Nakagawa H, Hayashi S, Imoto S, Stein L, Roth FP.

PLoS Genet. 2019 Jul 25;15(7):e1008227. doi: 10.1371/journal.pgen.1008227. eCollection 2019 Jul.

7.

Assessing predictions on fitness effects of missense variants in calmodulin.

Zhang J, Kinch LN, Cong Q, Katsonis P, Lichtarge O, Savojardo C, Babbi G, Martelli PL, Capriotti E, Casadio R, Garg A, Pal D, Weile J, Sun S, Verby M, Roth FP, Grishin NV.

Hum Mutat. 2019 Sep;40(9):1463-1473. doi: 10.1002/humu.23857. Epub 2019 Sep 3.

PMID:
31283071
8.

Characterizing ABC-Transporter Substrate-Likeness Using a Clean-Slate Genetic Background.

Sokolov A, Ashenden S, Sahin N, Lewis R, Erdem N, Ozaltan E, Bender A, Roth FP, Cokol M.

Front Pharmacol. 2019 Apr 25;10:448. doi: 10.3389/fphar.2019.00448. eCollection 2019.

9.

Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD).

Harish P, Malerba A, Lu-Nguyen N, Forrest L, Cappellari O, Roth F, Trollet C, Popplewell L, Dickson G.

J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):1016-1026. doi: 10.1002/jcsm.12438. Epub 2019 May 7.

10.

Decomposing electronic and lattice contributions in optical pump - X-ray probe transient inner-shell absorption spectroscopy of CuO.

Mahl J, Neppl S, Roth F, Borgwardt M, Saladrigas C, Toulson B, Cooper J, Rahman T, Bluhm H, Guo J, Yang W, Huse N, Eberhardt W, Gessner O.

Faraday Discuss. 2019 Jul 11;216(0):414-433. doi: 10.1039/c8fd00236c.

PMID:
31020294
11.

CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks.

Deneault E, Faheem M, White SH, Rodrigues DC, Sun S, Wei W, Piekna A, Thompson T, Howe JL, Chalil L, Kwan V, Walker S, Pasceri P, Roth FP, Yuen RK, Singh KK, Ellis J, Scherer SW.

Elife. 2019 Feb 12;8. pii: e40092. doi: 10.7554/eLife.40092.

12.

Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy.

Malerba A, Roth F, Harish P, Dhiab J, Lu-Nguyen N, Cappellari O, Jarmin S, Mahoudeau A, Ythier V, Lainé J, Negroni E, Abgueguen E, Simonelig M, Guedat P, Mouly V, Butler-Browne G, Voisset C, Dickson G, Trollet C.

Hum Mol Genet. 2019 May 15;28(10):1694-1708. doi: 10.1093/hmg/ddz007.

PMID:
30649389
13.

A web application and service for imputing and visualizing missense variant effect maps.

Wu Y, Weile J, Cote AG, Sun S, Knapp J, Verby M, Roth FP.

Bioinformatics. 2019 Sep 1;35(17):3191-3193. doi: 10.1093/bioinformatics/btz012.

14.

Testing interventions to improve response to a National Health Service Staff Survey.

Sizmur S, Roth F.

Health Serv Manage Res. 2019 Aug;32(3):124-129. doi: 10.1177/0951484818812443. Epub 2018 Nov 14. No abstract available.

PMID:
30426775
15.

Risk factors of brucellosis seropositivity in Bactrian camels of Mongolia.

Bayasgalan C, Chultemdorj T, Roth F, Zinsstag J, Hattendorf J, Badmaa B, Argamjav B, Schelling E.

BMC Vet Res. 2018 Nov 13;14(1):342. doi: 10.1186/s12917-018-1664-0.

16.

Transverse resonance island buckets for synchrotron-radiation based electron time-of-flight spectroscopy.

Arion T, Eberhardt W, Feikes J, Gottwald A, Goslawski P, Hoehl A, Kaser H, Kolbe M, Li J, Lupulescu C, Richter M, Ries M, Roth F, Ruprecht M, Tydecks T, Wüstefeld G.

Rev Sci Instrum. 2018 Oct;89(10):103114. doi: 10.1063/1.5046923.

PMID:
30399919
17.

Coral reef degradation affects the potential for reef recovery after disturbance.

Roth F, Saalmann F, Thomson T, Coker DJ, Villalobos R, Jones BH, Wild C, Carvalho S.

Mar Environ Res. 2018 Nov;142:48-58. doi: 10.1016/j.marenvres.2018.09.022. Epub 2018 Sep 20.

18.

Influence of Luting Materials on the Retention of Cemented Implant-Supported Crowns: An In Vitro Study.

Naumova EA, Roth F, Geis B, Baulig C, Arnold WH, Piwowarczyk A.

Materials (Basel). 2018 Sep 28;11(10). pii: E1853. doi: 10.3390/ma11101853.

19.

Facile reduction of graphene oxide suspensions and films using glass wafers.

Rabchinskii MK, Dideikin AT, Kirilenko DA, Baidakova MV, Shnitov VV, Roth F, Konyakhin SV, Besedina NA, Pavlov SI, Kuricyn RA, Lebedeva NM, Brunkov PN, Vul' AY.

Sci Rep. 2018 Sep 20;8(1):14154. doi: 10.1038/s41598-018-32488-x.

20.

Modeling the impact of drug interactions on therapeutic selectivity.

Weinstein ZB, Kuru N, Kiriakov S, Palmer AC, Khalil AS, Clemons PA, Zaman MH, Roth FP, Cokol M.

Nat Commun. 2018 Aug 27;9(1):3452. doi: 10.1038/s41467-018-05954-3.

21.

Synaptic entrainment of ectopic action potential generation in hippocampal pyramidal neurons.

Thome C, Roth FC, Obermayer J, Yanez A, Draguhn A, Egorov AV.

J Physiol. 2018 Nov;596(21):5237-5249. doi: 10.1113/JP276720. Epub 2018 Sep 19.

22.

Multiplexed assays of variant effects contribute to a growing genotype-phenotype atlas.

Weile J, Roth FP.

Hum Genet. 2018 Sep;137(9):665-678. doi: 10.1007/s00439-018-1916-x. Epub 2018 Aug 2. Review.

23.

A prospective randomized comparison of the minimally invasive direct anterior and the transgluteal approach for primary total hip arthroplasty.

Reichert JC, von Rottkay E, Roth F, Renz T, Hausmann J, Kranz J, Rackwitz L, Nöth U, Rudert M.

BMC Musculoskelet Disord. 2018 Jul 19;19(1):241. doi: 10.1186/s12891-018-2133-4.

24.

The Impact of Oncogenic EGFRvIII on the Proteome of Extracellular Vesicles Released from Glioblastoma Cells.

Choi D, Montermini L, Kim DK, Meehan B, Roth FP, Rak J.

Mol Cell Proteomics. 2018 Oct;17(10):1948-1964. doi: 10.1074/mcp.RA118.000644. Epub 2018 Jul 13.

25.

Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion genetics.

Díaz-Mejía JJ, Celaj A, Mellor JC, Coté A, Balint A, Ho B, Bansal P, Shaeri F, Gebbia M, Weile J, Verby M, Karkhanina A, Zhang Y, Wong C, Rich J, Prendergast D, Gupta G, Öztürk S, Durocher D, Brown GW, Roth FP.

Mol Syst Biol. 2018 May 28;14(5):e7985. doi: 10.15252/msb.20177985.

26.

Complementary Tuning of Na+ and K+ Channel Gating Underlies Fast and Energy-Efficient Action Potentials in GABAergic Interneuron Axons.

Hu H, Roth FC, Vandael D, Jonas P.

Neuron. 2018 Apr 4;98(1):156-165.e6. doi: 10.1016/j.neuron.2018.02.024.

27.

On the Electronic Structure of Cu Chlorophyllin and Its Breakdown Products: A Carbon K-Edge X-ray Absorption Spectroscopy Study.

Witte K, Mantouvalou I, Sánchez-de-Armas R, Lokstein H, Lebendig-Kuhla J, Jonas A, Roth F, Kanngießer B, Stiel H.

J Phys Chem B. 2018 Feb 15;122(6):1846-1851. doi: 10.1021/acs.jpcb.7b12108. Epub 2018 Feb 1.

PMID:
29350531
28.

A framework for exhaustively mapping functional missense variants.

Weile J, Sun S, Cote AG, Knapp J, Verby M, Mellor JC, Wu Y, Pons C, Wong C, van Lieshout N, Yang F, Tasan M, Tan G, Yang S, Fowler DM, Nussbaum R, Bloom JD, Vidal M, Hill DE, Aloy P, Roth FP.

Mol Syst Biol. 2017 Dec 21;13(12):957. doi: 10.15252/msb.20177908.

29.

Challenges to uptake of cancer education resources by rural Aboriginal Health Workers: the Cancer Healing Messages flipchart experience.

Bierbaum M, Plueckhahn T, Roth F, McNamara C, Ramsey I, Corsini N.

Rural Remote Health. 2017 Dec;17(4):4199. doi: 10.22605/RRH4199. Epub 2017 Dec 19.

30.

CRISPR/Cas9 System as a Valuable Genome Editing Tool for Wine Yeasts with Application to Decrease Urea Production.

Vigentini I, Gebbia M, Belotti A, Foschino R, Roth FP.

Front Microbiol. 2017 Nov 9;8:2194. doi: 10.3389/fmicb.2017.02194. eCollection 2017.

31.

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Wu CC, Hou S, Orr BA, Kuo BR, Youn YH, Ong T, Roth F, Eberhart CG, Robinson GW, Solecki DJ, Taketo MM, Gilbertson RJ, Roussel MF, Han YG.

Dev Cell. 2017 Dec 18;43(6):673-688.e5. doi: 10.1016/j.devcel.2017.10.011. Epub 2017 Nov 2.

32.

DALYs, dollars and dogs: how best to analyse the economics of controlling zoonoses.

Shaw APM, Rushton J, Roth F, Torgerson PR.

Rev Sci Tech. 2017 Apr;36(1):147-161. doi: 10.20506/rst.36.1.2618. Review.

33.

Variant Interpretation: Functional Assays to the Rescue.

Starita LM, Ahituv N, Dunham MJ, Kitzman JO, Roth FP, Seelig G, Shendure J, Fowler DM.

Am J Hum Genet. 2017 Sep 7;101(3):315-325. doi: 10.1016/j.ajhg.2017.07.014.

34.

Assessing predictions of fitness effects of missense mutations in SUMO-conjugating enzyme UBE2I.

Zhang J, Kinch LN, Cong Q, Weile J, Sun S, Cote AG, Roth FP, Grishin NV.

Hum Mutat. 2017 Sep;38(9):1051-1063. doi: 10.1002/humu.23293.

35.

Quantitative analysis of protein interaction network dynamics in yeast.

Celaj A, Schlecht U, Smith JD, Xu W, Suresh S, Miranda M, Aparicio AM, Proctor M, Davis RW, Roth FP, St Onge RP.

Mol Syst Biol. 2017 Jul 13;13(7):934. doi: 10.15252/msb.20177532.

36.

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target.

Jo M, Chung AY, Yachie N, Seo M, Jeon H, Nam Y, Seo Y, Kim E, Zhong Q, Vidal M, Park HC, Roth FP, Suk K.

Genome Res. 2017 Sep;27(9):1487-1500. doi: 10.1101/gr.211649.116. Epub 2017 Jun 8.

37.

The Impact of Lens Opacity on SD-OCT Retinal Nerve Fiber Layer and Bruch's Membrane Opening Measurements Using the Anatomical Positioning System (APS).

Mauschitz MM, Roth F, Holz FG, Breteler MMB, Finger RP.

Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2804-2809. doi: 10.1167/iovs.17-21675. Erratum in: Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10 ):4248.

PMID:
28564701
38.

Platelet-Rich Fibrin Conduits as an Alternative to Nerve Autografts for Peripheral Nerve Repair.

Roth F, Fernandes M, Valente SG, Santos JBG, Furukawa RB, Fernandes CH, Leite VM, Faloppa F.

J Reconstr Microsurg. 2017 Oct;33(8):549-556. doi: 10.1055/s-0037-1603355. Epub 2017 May 22. No abstract available.

PMID:
28561191
39.

Identifying pathogenicity of human variants via paralog-based yeast complementation.

Yang F, Sun S, Tan G, Costanzo M, Hill DE, Vidal M, Andrews BJ, Boone C, Roth FP.

PLoS Genet. 2017 May 25;13(5):e1006779. doi: 10.1371/journal.pgen.1006779. eCollection 2017 May.

40.

Systematic identification of phosphorylation-mediated protein interaction switches.

Betts MJ, Wichmann O, Utz M, Andre T, Petsalaki E, Minguez P, Parca L, Roth FP, Gavin AC, Bork P, Russell RB.

PLoS Comput Biol. 2017 Mar 27;13(3):e1005462. doi: 10.1371/journal.pcbi.1005462. eCollection 2017 Mar.

41.

A common class of transcripts with 5'-intron depletion, distinct early coding sequence features, and N1-methyladenosine modification.

Cenik C, Chua HN, Singh G, Akef A, Snyder MP, Palazzo AF, Moore MJ, Roth FP.

RNA. 2017 Mar;23(3):270-283. doi: 10.1261/rna.059105.116. Epub 2016 Dec 19.

42.

Exploring genetic suppression interactions on a global scale.

van Leeuwen J, Pons C, Mellor JC, Yamaguchi TN, Friesen H, Koschwanez J, Ušaj MM, Pechlaner M, Takar M, Ušaj M, VanderSluis B, Andrusiak K, Bansal P, Baryshnikova A, Boone CE, Cao J, Cote A, Gebbia M, Horecka G, Horecka I, Kuzmin E, Legro N, Liang W, van Lieshout N, McNee M, San Luis BJ, Shaeri F, Shuteriqi E, Sun S, Yang L, Youn JY, Yuen M, Costanzo M, Gingras AC, Aloy P, Oostenbrink C, Murray A, Graham TR, Myers CL, Andrews BJ, Roth FP, Boone C.

Science. 2016 Nov 4;354(6312). pii: aag0839.

43.

Taking Exception to Human Eugenics.

Roth FP, Wakeley J.

Genetics. 2016 Oct;204(2):821-823. No abstract available.

44.

Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.

Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, Sanglard D, Andes D, Nislow C, Coccetti P, Gingras AC, Heitman J, Gunatilaka AA, Cowen LE.

Nat Chem Biol. 2016 Oct;12(10):867-75. doi: 10.1038/nchembio.2165. Epub 2016 Aug 29.

45.

Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.

Klein P, Oloko M, Roth F, Montel V, Malerba A, Jarmin S, Gidaro T, Popplewell L, Perie S, Lacau St Guily J, de la Grange P, Antoniou MN, Dickson G, Butler-Browne G, Bastide B, Mouly V, Trollet C.

Nucleic Acids Res. 2016 Dec 15;44(22):10929-10945. Epub 2016 Aug 9.

46.

Downstream effects of hippocampal sharp wave ripple oscillations on medial entorhinal cortex layer V neurons in vitro.

Roth FC, Beyer KM, Both M, Draguhn A, Egorov AV.

Hippocampus. 2016 Dec;26(12):1493-1508. doi: 10.1002/hipo.22623. Epub 2016 Aug 18.

PMID:
27479916
47.

Irradiation-induced degradation of PTB7 investigated by valence band and S 2p photoelectron spectroscopy.

Darlatt E, Muhsin B, Roesch R, Lupulescu C, Roth F, Kolbe M, Gottwald A, Hoppe H, Richter M.

Nanotechnology. 2016 Aug 12;27(32):324005. doi: 10.1088/0957-4484/27/32/324005. Epub 2016 Jul 1.

PMID:
27363480
48.

An inter-species protein-protein interaction network across vast evolutionary distance.

Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M.

Mol Syst Biol. 2016 Apr 22;12(4):865. doi: 10.15252/msb.20156484.

49.

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP.

Mol Syst Biol. 2016 Apr 22;12(4):863. doi: 10.15252/msb.20156660.

50.

Impacts of a high-discharge submarine sewage outfall on water quality in the coastal zone of Salvador (Bahia, Brazil).

Roth F, Lessa GC, Wild C, Kikuchi RK, Naumann MS.

Mar Pollut Bull. 2016 May 15;106(1-2):43-8. doi: 10.1016/j.marpolbul.2016.03.048. Epub 2016 Mar 30.

PMID:
27038882

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