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Items: 1 to 50 of 156

1.

Ranibizumab Induces Regression of Diabetic Retinopathy in Most Patients at High Risk of Progression to Proliferative Diabetic Retinopathy.

Wykoff CC, Eichenbaum DA, Roth DB, Hill L, Fung AE, Haskova Z.

Ophthalmol Retina. 2018 Oct;2(10):997-1009. doi: 10.1016/j.oret.2018.06.005. Epub 2018 Aug 1.

PMID:
31047503
2.

Impact of Baseline Characteristics on Treatment Response to Intravitreal Aflibercept Injection for Wet Age-Related Macular Degeneration.

Ho AC, Saroj N, Baker K, Vitti R, Berliner AJ, Thompson D, Roth DB.

Ophthalmol Retina. 2018 Jul;2(7):676-683. doi: 10.1016/j.oret.2017.10.017. Epub 2017 Dec 27.

PMID:
31047376
3.

CLINICAL FINDINGS IN TRIAMCINOLONE-ASSOCIATED MACULOPATHY.

Fine HF, Reshef ER, Prenner JL, Shah SP, Grossniklaus HE, Roth DB.

Retina. 2019 Apr;39(4):761-765. doi: 10.1097/IAE.0000000000002007.

PMID:
29293206
4.

Actionable mutations in canine hemangiosarcoma.

Wang G, Wu M, Maloneyhuss MA, Wojcik J, Durham AC, Mason NJ, Roth DB.

PLoS One. 2017 Nov 30;12(11):e0188667. doi: 10.1371/journal.pone.0188667. eCollection 2017.

5.

The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect.

Hewitt SL, Wong JB, Lee JH, Nishana M, Chen H, Coussens M, Arnal SM, Blumenberg LM, Roth DB, Paull TT, Skok JA.

Cell Rep. 2017 Oct 24;21(4):979-993. doi: 10.1016/j.celrep.2017.09.084.

6.

The Impact of Electronic Reading Devices on Reading Speed and Comfort in Patients with Decreased Vision.

Feng HL, Roth DB, Fine HF, Prenner JL, Modi KK, Feuer WJ.

J Ophthalmol. 2017;2017:3584706. doi: 10.1155/2017/3584706. Epub 2017 Apr 20.

7.

RELENTLESS PLACOID CHORIORETINITIS: SUCCESSFUL LONG-TERM TREATMENT WITH INTRAVITREAL TRIAMCINOLONE.

Roth DB, Ballintine S, Mantopoulos D, Prenner J, Fine HF.

Retin Cases Brief Rep. 2019 Spring;13(2):150-153. doi: 10.1097/ICB.0000000000000546.

PMID:
28198750
8.

INTRAVITREAL OCRIPLASMIN IN CLINICAL PRACTICE: Predictors of Success, Visual Outcomes, and Complications.

Feng HL, Roth DB, Hasan A, Fine HF, Wheatley HM, Prenner JL, Shah SP, Modi KK, Feuer WJ.

Retina. 2018 Jan;38(1):128-136. doi: 10.1097/IAE.0000000000001505.

PMID:
28106706
9.

Macula Society Collaborative Retrospective Study of Ocriplasmin for Symptomatic Vitreomacular Adhesion.

Lim JI, Glassman AR, Aiello LP, Chakravarthy U, Flaxel CJ, Singerman LJ, Spaide RF, Roth DB; Macula Society Ocriplasmin for Vitreomacular Traction Study Group.

Ophthalmol Retina. 2017 Sep - Oct;1(5):413-420. doi: 10.1016/j.oret.2016.10.018. Epub 2017 Apr 25.

PMID:
31047572
10.

Clinical Utility of Next-Generation Sequencing for Oncogenic Mutations in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation.

Luskin MR, Carroll M, Lieberman D, Morrissette JJD, Zhao J, Crisalli L, Roth DB, Luger SM, Porter DL, Reshef R.

Biol Blood Marrow Transplant. 2016 Nov;22(11):1961-1967. doi: 10.1016/j.bbmt.2016.07.018. Epub 2016 Jul 28.

11.

Retina Specialists Treating Diabetic Macular Edema Recommend Different Approaches for Patients Than They Would Choose for Themselves.

Miller CG, Budoff G, Jeng-Miller KW, Fine HF, Roth DB, Prenner JL.

Ophthalmic Surg Lasers Imaging Retina. 2016 Jun 1;47(6):544-54. doi: 10.3928/23258160-20160601-06.

PMID:
27327284
12.

Building a Robust Tumor Profiling Program: Synergy between Next-Generation Sequencing and Targeted Single-Gene Testing.

Hiemenz MC, Kadauke S, Lieberman DB, Roth DB, Zhao J, Watt CD, Daber RD, Morrissette JJ.

PLoS One. 2016 Apr 4;11(4):e0152851. doi: 10.1371/journal.pone.0152851. eCollection 2016.

13.

Post-Marketing Survey of Adverse Events Following Ocriplasmin.

Shah SP, Jeng-Miller KW, Fine HF, Wheatley HM, Roth DB, Prenner JL.

Ophthalmic Surg Lasers Imaging Retina. 2016 Feb;47(2):156-60. doi: 10.3928/23258160-20160126-09.

PMID:
26878449
14.

RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair.

Lescale C, Abramowski V, Bedora-Faure M, Murigneux V, Vera G, Roth DB, Revy P, de Villartay JP, Deriano L.

Nat Commun. 2016 Feb 2;7:10529. doi: 10.1038/ncomms10529.

15.

Using "residual" FNA rinse and body fluid specimens for next-generation sequencing: An institutional experience.

Wei S, Lieberman D, Morrissette JJ, Baloch ZW, Roth DB, McGrath C.

Cancer Cytopathol. 2016 May;124(5):324-9. doi: 10.1002/cncy.21666. Epub 2015 Dec 18.

16.

Vitrectomy After ocriplasmin for VitreOmacular adhesion Or Macular hole (VAVOOM) study.

Greven MA, Garg S, Chiu B, Shah SP, Wolfe J, Fine HF, Roth DB, Robinson J, Mong J, Hsu J, Regillo C, Ho A, Haller JA.

Br J Ophthalmol. 2016 Sep;100(9):1211-5. doi: 10.1136/bjophthalmol-2015-307701. Epub 2015 Dec 9.

PMID:
26659344
17.

Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus.

Mijušković M, Chou YF, Gigi V, Lindsay CR, Shestova O, Lewis SM, Roth DB.

Cell Rep. 2015 Sep 22;12(11):1842-52. doi: 10.1016/j.celrep.2015.08.034. Epub 2015 Sep 10.

18.

Two or more dexamethasone intravitreal implants in treatment-naïve patients with macular edema due to retinal vein occlusion: subgroup analysis of a retrospective chart review study.

Dugel PU, Capone A Jr, Singer MA, Dreyer RF, Dodwell DG, Roth DB, Shi R, Walt JG, Scott LC, Hollander DA; SHASTA Study Group.

BMC Ophthalmol. 2015 Sep 4;15:118. doi: 10.1186/s12886-015-0106-z.

19.

V(D)J Recombination: Mechanism, Errors, and Fidelity.

Roth DB.

Microbiol Spectr. 2014 Dec;2(6). doi: 10.1128/microbiolspec.MDNA3-0041-2014. Review.

20.

Two or more dexamethasone intravitreal implants as monotherapy or in combination therapy for macular edema in retinal vein occlusion: subgroup analysis of a retrospective chart review study.

Singer MA, Capone A Jr, Dugel PU, Dreyer RF, Dodwell DG, Roth DB, Shi R, Walt JG, Scott LC, Hollander DA; SHASTA Study Group.

BMC Ophthalmol. 2015 Apr 1;15:33. doi: 10.1186/s12886-015-0018-y.

21.

Frequency and characteristics of intraocular inflammation after aflibercept injection.

Fine HF, Roth DB, Shah SP, Haque T, Wheatley HM.

Retina. 2015 Apr;35(4):681-6. doi: 10.1097/IAE.0000000000000398.

PMID:
25394166
22.

Acute exudative polymorphous vitelliform maculopathy in a young man: a case report.

Modi KK, Roth DB, Green SN.

Retin Cases Brief Rep. 2014 Summer;8(3):200-4. doi: 10.1097/ICB.0000000000000042.

PMID:
25372438
23.

RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of 'alternative NHEJ'.

Gigi V, Lewis S, Shestova O, Mijušković M, Deriano L, Meng W, Luning Prak ET, Roth DB.

Nucleic Acids Res. 2014 Jun;42(10):6352-64. doi: 10.1093/nar/gku295. Epub 2014 Apr 20.

24.

An unbiased method for detection of genome-wide off-target effects in cell lines treated with zinc finger nucleases.

Lindsay CR, Roth DB.

Methods Mol Biol. 2014;1114:353-69. doi: 10.1007/978-1-62703-761-7_23.

PMID:
24557915
25.

Modernizing the nonhomologous end-joining repertoire: alternative and classical NHEJ share the stage.

Deriano L, Roth DB.

Annu Rev Genet. 2013;47:433-55. doi: 10.1146/annurev-genet-110711-155540. Epub 2013 Sep 11. Review.

26.

RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.

Coussens MA, Wendland RL, Deriano L, Lindsay CR, Arnal SM, Roth DB.

Cell Rep. 2013 Sep 12;4(5):870-8. doi: 10.1016/j.celrep.2013.07.041. Epub 2013 Aug 29.

27.

The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage.

Chaumeil J, Micsinai M, Ntziachristos P, Roth DB, Aifantis I, Kluger Y, Deriano L, Skok JA.

Nat Commun. 2013;4:2231. doi: 10.1038/ncomms3231.

28.

Efficacy and safety of two or more dexamethasone intravitreal implant injections for treatment of macular edema related to retinal vein occlusion (Shasta study).

Capone A Jr, Singer MA, Dodwell DG, Dreyer RF, Oh KT, Roth DB, Walt JG, Scott LC, Hollander DA.

Retina. 2014 Feb;34(2):342-51. doi: 10.1097/IAE.0b013e318297f842.

PMID:
23846381
29.

Retrobulbar gas after macular hole surgery: a case report.

Roth DB, Ballintine SD.

Retin Cases Brief Rep. 2013 Summer;7(3):188-92. doi: 10.1097/ICB.0b013e31827cee14.

PMID:
25391102
30.

Incidence of choroidal neovascularization in the fellow eye in the comparison of age-related macular degeneration treatments trials.

Maguire MG, Daniel E, Shah AR, Grunwald JE, Hagstrom SA, Avery RL, Huang J, Martin RW, Roth DB, Castellarin AA, Bakri SJ, Fine SL, Martin DF; Comparison of Age-Related Macular Degeneration Treatments Trials (CATT Research Group).

Ophthalmology. 2013 Oct;120(10):2035-41. doi: 10.1016/j.ophtha.2013.03.017. Epub 2013 May 22.

31.

A streamlined method for detecting structural variants in cancer genomes by short read paired-end sequencing.

Mijušković M, Brown SM, Tang Z, Lindsay CR, Efstathiadis E, Deriano L, Roth DB.

PLoS One. 2012;7(10):e48314. doi: 10.1371/journal.pone.0048314. Epub 2012 Oct 29.

32.

The 1-year results of CLEAR-IT 2, a phase 2 study of vascular endothelial growth factor trap-eye dosed as-needed after 12-week fixed dosing.

Heier JS, Boyer D, Nguyen QD, Marcus D, Roth DB, Yancopoulos G, Stahl N, Ingerman A, Vitti R, Berliner AJ, Yang K, Brown DM; CLEAR-IT 2 Investigators.

Ophthalmology. 2011 Jun;118(6):1098-106. doi: 10.1016/j.ophtha.2011.03.020. Erratum in: Ophthalmology. 2011 Sep;118(9):1700.

PMID:
21640258
33.

The RAG2 C terminus suppresses genomic instability and lymphomagenesis.

Deriano L, Chaumeil J, Coussens M, Multani A, Chou Y, Alekseyenko AV, Chang S, Skok JA, Roth DB.

Nature. 2011 Mar 3;471(7336):119-23. doi: 10.1038/nature09755.

34.

Publication rates of registered clinical trials in macular degeneration.

Prenner JL, Driscoll SJ, Fine HF, Salz DA, Roth DB.

Retina. 2011 Feb;31(2):401-4. doi: 10.1097/IAE.0b013e3181eef2ad.

PMID:
21221049
35.
36.

Non-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways.

Arnal SM, Holub AJ, Salus SS, Roth DB.

Nucleic Acids Res. 2010 May;38(9):2944-54. doi: 10.1093/nar/gkp1252. Epub 2010 Feb 4.

37.

Intravitreal triamcinolone acetonide preceding photodynamic therapy for exudative age-related macular degeneration.

Roth DB, Kulkarni KM, Walsman S, Modi A.

Ophthalmic Surg Lasers Imaging. 2009 Sep-Oct;40(5):467-71. doi: 10.3928/15428877-20090901-05.

PMID:
19772270
38.

Recent insights into the formation of RAG-induced chromosomal translocations.

Brandt VL, Roth DB.

Adv Exp Med Biol. 2009;650:32-45. Review.

PMID:
19731799
39.

Base flipping in V(D)J recombination: insights into the mechanism of hairpin formation, the 12/23 rule, and the coordination of double-strand breaks.

Bischerour J, Lu C, Roth DB, Chalmers R.

Mol Cell Biol. 2009 Nov;29(21):5889-99. doi: 10.1128/MCB.00187-09. Epub 2009 Aug 31.

40.

Systemic adverse events after bevacizumab.

Roth DB, King A, Weiss M, Klein D.

Ophthalmology. 2009 Jun;116(6):1226.e1. doi: 10.1016/j.ophtha.2009.02.011. No abstract available.

PMID:
19486800
41.

Roles for NBS1 in alternative nonhomologous end-joining of V(D)J recombination intermediates.

Deriano L, Stracker TH, Baker A, Petrini JH, Roth DB.

Mol Cell. 2009 Apr 10;34(1):13-25. doi: 10.1016/j.molcel.2009.03.009.

42.

Macular ischemia associated with imatinib mesylate therapy for chronic myeloid leukemia.

Roth DB, Akbari S, Rothstein A.

Retin Cases Brief Rep. 2009 Spring;3(2):161-4. doi: 10.1097/ICB.0b013e318177f9d7.

PMID:
25391063
43.

Long-term incidence and timing of intraocular hypertension after intravitreal triamcinolone acetonide injection.

Roth DB, Verma V, Realini T, Prenner JL, Feuer WJ, Fechtner RD.

Ophthalmology. 2009 Mar;116(3):455-60. doi: 10.1016/j.ophtha.2008.10.002. Epub 2009 Jan 20.

PMID:
19157561
44.

Intravitreal triamcinolone acetonide injections in the treatment of retinal vein occlusions.

Roth DB, Cukras C, Radhakrishnan R, Feuer WJ, Yarian DL, Green SN, Wheatley HM, Prenner J.

Ophthalmic Surg Lasers Imaging. 2008 Nov-Dec;39(6):446-54.

PMID:
19065973
45.

Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability.

Stracker TH, Williams BR, Deriano L, Theunissen JW, Adelman CA, Roth DB, Petrini JH.

Mol Cell Biol. 2009 Jan;29(2):503-14. doi: 10.1128/MCB.01354-08. Epub 2008 Nov 17.

47.

Distinguishing between infectious and noninfectious endophthalmitis after intravitreal triamcinolone injection.

Roth DB, Flynn HW Jr.

Am J Ophthalmol. 2008 Sep;146(3):346-347. doi: 10.1016/j.ajo.2008.04.037. No abstract available.

PMID:
18724979
48.

Incidence of noninfectious endophthalmitis after intravitreal injection of preservative-free triamcinolone acetonide.

Roth DB, Prenner JL, Krajnyk O.

Retin Cases Brief Rep. 2008 Summer;2(3):247-9. doi: 10.1097/ICB.0b013e3181658cd5.

PMID:
25390101
49.

Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition.

Lu CP, Posey JE, Roth DB.

Nucleic Acids Res. 2008 May;36(9):2864-73. doi: 10.1093/nar/gkn128. Epub 2008 Mar 29.

50.

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