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A propensity analysis comparing definitive chemo-radiotherapy for muscle-invasive squamous cell carcinoma of the bladder vs. urothelial carcinoma of the bladder using the National Cancer Database.

Fischer-Valuck BW, Michalski JM, Contreras JA, Brenneman R, Christodouleas JP, Abraham CD, Kim EH, Arora VK, Bullock AD, Carmona R, Figenshau RS, Grubb R 3rd, Knoche EM, Pachynski RK, Picus J, Roth BJ, Sargos P, Andriole GL, Gay HA, Baumann BC.

Clin Transl Radiat Oncol. 2018 Dec 12;15:38-41. doi: 10.1016/j.ctro.2018.12.001. eCollection 2019 Feb.


[Instillation therapies for urothelial carcinoma of the upper urinary tract].

Bosshard P, Thalmann GN, Roth B.

Urologe A. 2019 Jan 16. doi: 10.1007/s00120-018-0830-0. [Epub ahead of print] Review. German.


AXIN1 in Plasma or Serum Is a Potential New Biomarker for Endometriosis.

Ek M, Roth B, Engström G, Ohlsson B.

Int J Mol Sci. 2019 Jan 7;20(1). pii: E189. doi: 10.3390/ijms20010189.


Far away from the lamppost.

Oprea TI, Jan L, Johnson GL, Roth BL, Ma'ayan A, Schürer S, Shoichet BK, Sklar LA, McManus MT.

PLoS Biol. 2018 Dec 11;16(12):e3000067. doi: 10.1371/journal.pbio.3000067. eCollection 2018 Dec.


Dietary intervention with an Okinawan-based Nordic diet in type 2 diabetes renders decreased interleukin-18 concentrations and increased neurofilament light concentrations in plasma.

Nilholm C, Roth B, Höglund P, Blennow K, Englund E, Hansson O, Zetterberg H, Ohlsson B.

Nutr Res. 2018 Dec;60:13-25. doi: 10.1016/j.nutres.2018.08.002. Epub 2018 Aug 19.


Efficacy of standard and low dose hydrochlorothiazide in the recurrence prevention of calcium nephrolithiasis (NOSTONE trial): protocol for a randomized double-blind placebo-controlled trial.

Dhayat NA, Faller N, Bonny O, Mohebbi N, Ritter A, Pellegrini L, Bedino G, Schönholzer C, Venzin RM, Hüsler C, Koneth I, Del Giorno R, Gabutti L, Amico P, Mayr M, Odermatt U, Buchkremer F, Ernandez T, Stoermann-Chopard C, Teta D, Rintelen F, Roumet M, Irincheeva I, Trelle S, Tamò L, Roth B, Vogt B, Fuster DG.

BMC Nephrol. 2018 Dec 10;19(1):349. doi: 10.1186/s12882-018-1144-6.


Optoacoustic inversion via convolution kernel reconstruction in the paraxial approximation and beyond.

Melchert O, Wollweber M, Roth B.

Photoacoustics. 2018 Nov 5;13:1-5. doi: 10.1016/j.pacs.2018.10.004. eCollection 2019 Mar.


Polymer-based diffractive optical elements for rear end automotive applications: design and fabrication process.

Khan MS, Rahlves M, Lachmayer R, Roth B.

Appl Opt. 2018 Oct 20;57(30):9106-9113. doi: 10.1364/AO.57.009106.


Evaluating the Performance of Functionalized Carbon Structures with Integrated Optical Fiber Sensors under Practical Conditions.

Bremer K, Alwis LSM, Weigand F, Kuhne M, Zheng Y, Krüger M, Helbig R, Roth B.

Sensors (Basel). 2018 Nov 14;18(11). pii: E3923. doi: 10.3390/s18113923.


Forty years of cisplatin-based chemotherapy in muscle-invasive bladder cancer: are we understanding how, who and when?

Schardt J, Roth B, Seiler R.

World J Urol. 2018 Nov 3. doi: 10.1007/s00345-018-2544-8. [Epub ahead of print]


Longer colonic transit time is associated with laxative and drug use, lifestyle factors, and symptoms of constipation.

Bohlin J, Dahlin E, Dreja J, Roth B, Ekberg O, Ohlsson B.

Acta Radiol Open. 2018 Oct 22;7(10):2058460118807232. doi: 10.1177/2058460118807232. eCollection 2018 Sep.


A simple approach for multi-targeted shRNA-mediated inducible knockdowns using Sleeping Beauty vectors.

Fink S, Zugelder L, Roth B, Brandt E, Meloche S, Izsvák Z, Bargou RC, Stühmer T.

PLoS One. 2018 Oct 19;13(10):e0205585. doi: 10.1371/journal.pone.0205585. eCollection 2018.


Characteristics of endometriosis: A case-cohort study showing elevated IgG titers against the TSH receptor (TRAb) and mental comorbidity.

Ek M, Roth B, Nilsson PM, Ohlsson B.

Eur J Obstet Gynecol Reprod Biol. 2018 Dec;231:8-14. doi: 10.1016/j.ejogrb.2018.09.034. Epub 2018 Oct 6.


1H, 13C, and 15N resonance assignments of N-acetylmuramyl-L-alanine amidase (AmiC) N-terminal domain (NTD) from Neisseria gonorrhoeae.

Young BF, Roth BM, Davies C.

Biomol NMR Assign. 2018 Oct 1. doi: 10.1007/s12104-018-9852-1. [Epub ahead of print]


Discrepancies in Kappa Opioid Agonist Binding Revealed through PET Imaging.

Placzek MS, Schroeder FA, Che T, Wey HY, Neelamegam R, Wang C, Roth BL, Hooker JM.

ACS Chem Neurosci. 2018 Oct 17. doi: 10.1021/acschemneuro.8b00293. [Epub ahead of print]


Risk factors associated with neonatal thrombocytopenia in pregnant women with immune thrombocytopenic purpura.

Rottenstreich A, Israeli N, Roth B, Elchalal U, Amsalem H, Da'as N, Rottenstreich M, Kalish Y.

J Matern Fetal Neonatal Med. 2018 Nov 4:1-7. doi: 10.1080/14767058.2018.1523891. [Epub ahead of print]


The Violence of Uncertainty - Undermining Immigrant and Refugee Health.

Grace BL, Bais R, Roth BJ.

N Engl J Med. 2018 Sep 6;379(10):904-905. doi: 10.1056/NEJMp1807424. No abstract available.


Phosphoproteomics Illuminates Opioid Actions.

Che T, Roth BL.

Biochemistry. 2018 Sep 25;57(38):5505-5506. doi: 10.1021/acs.biochem.8b00809. Epub 2018 Sep 13.


Social Workers Must Stand Up for Immigrant Rights: Strategies for Action.

Negi NJ, Roth B, Held ML, Scott J, Boyas J.

Soc Work. 2018 Oct 1;63(4):373-376. doi: 10.1093/sw/swy039. No abstract available.


Structural determinants of 5-HT2B receptor activation and biased agonism.

McCorvy JD, Wacker D, Wang S, Agegnehu B, Liu J, Lansu K, Tribo AR, Olsen RHJ, Che T, Jin J, Roth BL.

Nat Struct Mol Biol. 2018 Sep;25(9):787-796. doi: 10.1038/s41594-018-0116-7. Epub 2018 Aug 20.


The mechanical bidomain model of cardiac muscle with curving fibers.

Sharma K, Roth BJ.

Phys Biol. 2018 Sep 12;15(6):066012. doi: 10.1088/1478-3975/aadacd.


Polymer Based Whispering Gallery Mode Humidity Sensor.

Petermann AB, Hildebrandt T, Morgner U, Roth BW, Meinhardt-Wollweber M.

Sensors (Basel). 2018 Jul 22;18(7). pii: E2383. doi: 10.3390/s18072383.


Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets.

Weiss DR, Karpiak J, Huang XP, Sassano MF, Lyu J, Roth BL, Shoichet BK.

J Med Chem. 2018 Aug 9;61(15):6830-6845. doi: 10.1021/acs.jmedchem.8b00718. Epub 2018 Jul 24.


Differences in cost consciousness between physicians and nurses in German neonatal intensive care units.

Schmitz H, Martakis K, Roth B, Pfaff H, Scholten N.

Acta Paediatr. 2019 Feb;108(2):245-252. doi: 10.1111/apa.14479. Epub 2018 Jul 26.


Activation mechanisms for a universal signalling protein.

Krumm B, Roth BL.

Nature. 2018 May;557(7705):318-319. doi: 10.1038/d41586-018-04977-6. No abstract available.


Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3.

Panneer Selvam S, Roth BM, Nganga R, Kim J, Cooley MA, Helke K, Smith CD, Ogretmen B.

J Biol Chem. 2018 Jun 22;293(25):9784-9800. doi: 10.1074/jbc.RA118.003506. Epub 2018 May 10.


High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening.

Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, Hanson MA, Liu ZJ, Wang MW, Stevens RC, Shui W.

Chem Sci. 2018 Feb 20;9(12):3192-3199. doi: 10.1039/c7sc04698g. eCollection 2018 Mar 28.


Post-operative Weaning of Opioids After Ambulatory Surgery: the Importance of Physician Stewardship.

Roth B, Boateng A, Berken A, Carlyle D, Vadivelu N.

Curr Pain Headache Rep. 2018 May 3;22(6):40. doi: 10.1007/s11916-018-0694-4. Review.


Antiphospholipid antibody profile-based outcome of purely vascular and purely obstetric antiphospholipid syndrome.

Rottenstreich A, Arad A, Terespolsky H, Elchalal U, Amsalm H, Roth B, Kalish Y.

J Thromb Thrombolysis. 2018 Aug;46(2):166-173. doi: 10.1007/s11239-018-1672-8.


Long-Period Gratings in Highly Germanium-Doped, Single-Mode Optical Fibers for Sensing Applications.

Schlangen S, Bremer K, Zheng Y, Böhm S, Steinke M, Wellmann F, Neumann J, Roth B, Overmeyer L.

Sensors (Basel). 2018 Apr 27;18(5). pii: E1363. doi: 10.3390/s18051363.


Donated chemical probes for open science.

Müller S, Ackloo S, Arrowsmith CH, Bauser M, Baryza JL, Blagg J, Böttcher J, Bountra C, Brown PJ, Bunnage ME, Carter AJ, Damerell D, Dötsch V, Drewry DH, Edwards AM, Edwards J, Elkins JM, Fischer C, Frye SV, Gollner A, Grimshaw CE, IJzerman A, Hanke T, Hartung IV, Hitchcock S, Howe T, Hughes TV, Laufer S, Li VM, Liras S, Marsden BD, Matsui H, Mathias J, O'Hagan RC, Owen DR, Pande V, Rauh D, Rosenberg SH, Roth BL, Schneider NS, Scholten C, Singh Saikatendu K, Simeonov A, Takizawa M, Tse C, Thompson PR, Treiber DK, Viana AY, Wells CI, Willson TM, Zuercher WJ, Knapp S, Mueller-Fahrnow A.

Elife. 2018 Apr 20;7. pii: e34311. doi: 10.7554/eLife.34311.


Alignments of endocrine, anthropometric, and metabolic parameters in type 2 diabetes after intervention with an Okinawa-based Nordic diet.

Ohlsson B, Darwiche G, Roth B, Höglund P.

Food Nutr Res. 2018 Mar 14;62. doi: 10.29219/fnr.v62.1328. eCollection 2018.


Conference Report: Psychiatric Genomics Consortium Meeting: Pathways to Drugs, London, March 2017.

Gaspar HA, Collier DA, Geschwind DH, Lewis CM, Li Q, Roth BL, Sullivan PF, Breen G.

Biol Psychiatry. 2018 Sep 15;84(6):e49-e50. doi: 10.1016/j.biopsych.2018.01.024. Epub 2018 Feb 8. No abstract available.


Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):377. doi: 10.1038/nrd.2018.52. Epub 2018 Mar 23.


Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.

Roth BL, Gibbons S, Arunotayanun W, Huang XP, Setola V, Treble R, Iversen L.

PLoS One. 2018 Mar 22;13(3):e0194984. doi: 10.1371/journal.pone.0194984. eCollection 2018.


Exploring the differential impact of individual and organizational factors on organizational commitment of physicians and nurses.

Miedaner F, Kuntz L, Enke C, Roth B, Nitzsche A.

BMC Health Serv Res. 2018 Mar 15;18(1):180. doi: 10.1186/s12913-018-2977-1.


Great Cause-Small Effect: Undeclared Genetically Engineered Orange Petunias Harbor an Inefficient Dihydroflavonol 4-Reductase.

Haselmair-Gosch C, Miosic S, Nitarska D, Roth BL, Walliser B, Paltram R, Lucaciu RC, Eidenberger L, Rattei T, Olbricht K, Stich K, Halbwirth H.

Front Plant Sci. 2018 Feb 28;9:149. doi: 10.3389/fpls.2018.00149. eCollection 2018.


Direct-acting oral anticoagulant drug level monitoring in clinical patient management.

Rottenstreich A, Zacks N, Kleinstern G, Raccah BH, Roth B, Da'as N, Kalish Y.

J Thromb Thrombolysis. 2018 May;45(4):543-549. doi: 10.1007/s11239-018-1643-0.


Abundance of Enterobacteriaceae in the colon mucosa in diverticular disease.

Linninge C, Roth B, Erlanson-Albertsson C, Molin G, Toth E, Ohlsson B.

World J Gastrointest Pathophysiol. 2018 Feb 15;9(1):18-27. doi: 10.4291/wjgp.v9.i1.18.


Unexplored therapeutic opportunities in the human genome.

Oprea TI, Bologa CG, Brunak S, Campbell A, Gan GN, Gaulton A, Gomez SM, Guha R, Hersey A, Holmes J, Jadhav A, Jensen LJ, Johnson GL, Karlson A, Leach AR, Ma'ayan A, Malovannaya A, Mani S, Mathias SL, McManus MT, Meehan TF, von Mering C, Muthas D, Nguyen DT, Overington JP, Papadatos G, Qin J, Reich C, Roth BL, Schürer SC, Simeonov A, Sklar LA, Southall N, Tomita S, Tudose I, Ursu O, Vidovic D, Waller A, Westergaard D, Yang JJ, Zahoránszky-Köhalmi G.

Nat Rev Drug Discov. 2018 May;17(5):317-332. doi: 10.1038/nrd.2018.14. Epub 2018 Mar 23. Review. Erratum in: Nat Rev Drug Discov. 2018 Mar 23;:.


An Accurate Diagnostic Pathway Helps to Correctly Distinguish Between the Possible Causes of Acute Scrotum.

Roth B, Giannakis I, Ricklin ME, Thalmann GN, Exadaktylos AK.

Oman Med J. 2018 Jan;33(1):55-60. doi: 10.5001/omj.2018.10.


Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone.

Wang S, Che T, Levit A, Shoichet BK, Wacker D, Roth BL.

Nature. 2018 Mar 8;555(7695):269-273. doi: 10.1038/nature25758. Epub 2018 Jan 24.


The Structure of the Biofilm-controlling Response Regulator BfmR from Acinetobacter baumannii Reveals Details of Its DNA-binding Mechanism.

Draughn GL, Milton ME, Feldmann EA, Bobay BG, Roth BM, Olson AL, Thompson RJ, Actis LA, Davies C, Cavanagh J.

J Mol Biol. 2018 Mar 16;430(6):806-821. doi: 10.1016/j.jmb.2018.02.002. Epub 2018 Feb 10.


Assessment of the Prosthetic Replacement of Ocular Surface Ecosystem (PROSE) scleral lens on visual acuity for corneal irregularity and ocular surface disease.

Parra AS, Roth BM, Nguyen TM, Wang L, Pflugfelder SC, Al-Mohtaseb Z.

Ocul Surf. 2018 Apr;16(2):254-258. doi: 10.1016/j.jtos.2018.01.003. Epub 2018 Feb 6.


5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology.

Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, Wacker D, Han GW, Cheng J, Katritch V, Jensen AA, Hanson MA, Zhao S, Gloriam DE, Roth BL, Stevens RC, Liu ZJ.

Cell. 2018 Feb 8;172(4):719-730.e14. doi: 10.1016/j.cell.2018.01.001. Epub 2018 Feb 1.


Differences Between Snakebites with Concomitant Use of Alcohol or Drugs and Single Snakebites.

Schulte J, Kleinschmidt KC, Domanski K, Smith EA, Haynes A, Roth B.

South Med J. 2018 Feb;111(2):113-117. doi: 10.14423/SMJ.0000000000000760.


Quality of Life Outcomes for Cabozantinib Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma: METEOR Phase III Randomized Trial.

Cella D, Escudier B, Tannir NM, Powles T, Donskov F, Peltola K, Schmidinger M, Heng DYC, Mainwaring PN, Hammers HJ, Lee JL, Roth BJ, Marteau F, Williams P, Baer J, Mangeshkar M, Scheffold C, Hutson TE, Pal S, Motzer RJ, Choueiri TK.

J Clin Oncol. 2018 Mar 10;36(8):757-764. doi: 10.1200/JCO.2017.75.2170. Epub 2018 Jan 29.


Volume, size, professionals' specialization and nutrition management of NICUs and their association with treatment quality in VLBW infants.

Miedaner F, Langhammer K, Enke C, Göpel W, Kribs A, Nitzsche A, Riedel R, Woopen C, Kuntz L, Roth B.

J Perinatol. 2018 Apr;38(4):402-410. doi: 10.1038/s41372-017-0036-0. Epub 2018 Jan 25.


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