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Items: 1 to 50 of 115

1.

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S.

Immunity. 2018 Dec 18;49(6):1062-1076.e6. doi: 10.1016/j.immuni.2018.09.018. Epub 2018 Nov 13.

2.

Characterization of a chimeric chemokine as a specific ligand for ACKR3.

Ameti R, Melgrati S, Radice E, Cameroni E, Hub E, Thelen S, Rot A, Thelen M.

J Leukoc Biol. 2018 Aug;104(2):391-400. doi: 10.1002/JLB.2MA1217-509R. Epub 2018 Mar 30.

3.

Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.

Duchene J, Novitzky-Basso I, Thiriot A, Casanova-Acebes M, Bianchini M, Etheridge SL, Hub E, Nitz K, Artinger K, Eller K, Caamaño J, Rülicke T, Moss P, Megens RTA, von Andrian UH, Hidalgo A, Weber C, Rot A.

Nat Immunol. 2017 Jul;18(7):753-761. doi: 10.1038/ni.3763. Epub 2017 May 29.

4.

Differential DARC/ACKR1 expression distinguishes venular from non-venular endothelial cells in murine tissues.

Thiriot A, Perdomo C, Cheng G, Novitzky-Basso I, McArdle S, Kishimoto JK, Barreiro O, Mazo I, Triboulet R, Ley K, Rot A, von Andrian UH.

BMC Biol. 2017 May 19;15(1):45. doi: 10.1186/s12915-017-0381-7.

5.

Human liver sinusoidal endothelial cells promote intracellular crawling of lymphocytes during recruitment: A new step in migration.

Patten DA, Wilson GK, Bailey D, Shaw RK, Jalkanen S, Salmi M, Rot A, Weston CJ, Adams DH, Shetty S.

Hepatology. 2017 Jan;65(1):294-309. doi: 10.1002/hep.28879. Epub 2016 Nov 25.

6.

Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL.

Cordeiro OG, Chypre M, Brouard N, Rauber S, Alloush F, Romera-Hernandez M, Bénézech C, Li Z, Eckly A, Coles MC, Rot A, Yagita H, Léon C, Ludewig B, Cupedo T, Lanza F, Mueller CG.

PLoS One. 2016 Mar 24;11(3):e0151848. doi: 10.1371/journal.pone.0151848. eCollection 2016.

7.

MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis.

Alampour-Rajabi S, El Bounkari O, Rot A, Müller-Newen G, Bachelerie F, Gawaz M, Weber C, Schober A, Bernhagen J.

FASEB J. 2015 Nov;29(11):4497-511. doi: 10.1096/fj.15-273904. Epub 2015 Jul 2.

PMID:
26139098
8.

An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15.

Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S, Thelen M.

Br J Pharmacol. 2015 Aug;172(16):3945-9. doi: 10.1111/bph.13182. Epub 2015 Jun 26. Review.

9.

CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice.

Lucas B, White AJ, Ulvmar MH, Nibbs RJ, Sitnik KM, Agace WW, Jenkinson WE, Anderson G, Rot A.

Eur J Immunol. 2015 Feb;45(2):574-83. doi: 10.1002/eji.201445015. Epub 2015 Jan 16.

10.

Efficacy of the entomopathogenic fungus Metarhizium brunneum in controlling the tick Rhipicephalus annulatus under field conditions.

Samish M, Rot A, Ment D, Barel S, Glazer I, Gindin G.

Vet Parasitol. 2014 Dec 15;206(3-4):258-66.

PMID:
25468024
11.

The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer.

Ward ST, Li KK, Hepburn E, Weston CJ, Curbishley SM, Reynolds GM, Hejmadi RK, Bicknell R, Eksteen B, Ismail T, Rot A, Adams DH.

Br J Cancer. 2015 Jan 20;112(2):319-28. doi: 10.1038/bjc.2014.572. Epub 2014 Nov 18.

12.

The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes.

Ulvmar MH, Werth K, Braun A, Kelay P, Hub E, Eller K, Chan L, Lucas B, Novitzky-Basso I, Nakamura K, Rülicke T, Nibbs RJ, Worbs T, Förster R, Rot A.

Nat Immunol. 2014 Jul;15(7):623-30. doi: 10.1038/ni.2889. Epub 2014 May 11.

PMID:
24813163
13.

DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation.

Minten C, Alt C, Gentner M, Frei E, Deutsch U, Lyck R, Schaeren-Wiemers N, Rot A, Engelhardt B.

Brain. 2014 May;137(Pt 5):1454-69. doi: 10.1093/brain/awu045. Epub 2014 Mar 12.

14.

New nomenclature for atypical chemokine receptors.

Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S, Thelen M.

Nat Immunol. 2014 Mar;15(3):207-8. doi: 10.1038/ni.2812. No abstract available.

PMID:
24549061
15.

International Union of Basic and Clinical Pharmacology. [corrected]. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors.

Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH, Locati M, Luster AD, Mantovani A, Matsushima K, Murphy PM, Nibbs R, Nomiyama H, Power CA, Proudfoot AE, Rosenkilde MM, Rot A, Sozzani S, Thelen M, Yoshie O, Zlotnik A.

Pharmacol Rev. 2013 Nov 11;66(1):1-79. doi: 10.1124/pr.113.007724. Print 2014. Review. Erratum in: Pharmacol Rev. 2014 Apr;66(2):467.

16.

Microarray analyses demonstrate the involvement of type I interferons in psoriasiform pathology development in D6-deficient mice.

Baldwin HM, Pallas K, King V, Jamieson T, McKimmie CS, Nibbs RJ, Carballido JM, Jaritz M, Rot A, Graham GJ.

J Biol Chem. 2013 Dec 20;288(51):36473-83. doi: 10.1074/jbc.M113.491563. Epub 2013 Nov 5.

17.

Cuticular fatty acid profile analysis of three Rhipicephalus tick species (Acari: Ixodidae).

Shimshoni JA, Erster O, Rot A, Cuneah O, Soback S, Shkap V.

Exp Appl Acarol. 2013 Dec;61(4):481-9. doi: 10.1007/s10493-013-9713-7. Epub 2013 Jun 26.

PMID:
23801037
18.

Cell-autonomous regulation of neutrophil migration by the D6 chemokine decoy receptor.

Rot A, McKimmie C, Burt CL, Pallas KJ, Jamieson T, Pruenster M, Horuk R, Nibbs RJB, Graham GJ.

J Immunol. 2013 Jun 15;190(12):6450-6456. doi: 10.4049/jimmunol.1201429. Epub 2013 May 13.

19.

A chemokine self-presentation mechanism involving formation of endothelial surface microstructures.

Whittall C, Kehoe O, King S, Rot A, Patterson A, Middleton J.

J Immunol. 2013 Feb 15;190(4):1725-36. doi: 10.4049/jimmunol.1200867. Epub 2013 Jan 16.

20.

On-host control of the brown dog tick Rhipicephalus sanguineus Latreille (Acari: Ixodidae) by Metarhizium brunneum (Hypocreales: Clavicipitaceae).

Rot A, Gindin G, Ment D, Mishoutchenko A, Glazer I, Samish M.

Vet Parasitol. 2013 Mar 31;193(1-3):229-37. doi: 10.1016/j.vetpar.2012.11.020. Epub 2012 Nov 21.

PMID:
23267821
21.

CD8 T cells induce T-bet-dependent migration toward CXCR3 ligands by differentiated B cells produced during responses to alum-protein vaccines.

Serre K, Cunningham AF, Coughlan RE, Lino AC, Rot A, Hub E, Moser K, Manz R, Ferraro A, Bird R, Toellner KM, Demengeot J, MacLennan IC, Mohr E.

Blood. 2012 Nov 29;120(23):4552-9. doi: 10.1182/blood-2012-03-417733. Epub 2012 Oct 11.

PMID:
23065152
22.

Duffy antigen receptor for chemokines and its involvement in patterning and control of inflammatory chemokines.

Novitzky-Basso I, Rot A.

Front Immunol. 2012 Aug 17;3:266. doi: 10.3389/fimmu.2012.00266. eCollection 2012.

23.

Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis.

Singh MD, King V, Baldwin H, Burden D, Thorrat A, Holmes S, McInnes IB, Nicoll R, Shams K, Pallas K, Jamieson T, Lee KM, Carballido JM, Rot A, Graham GJ.

Am J Pathol. 2012 Oct;181(4):1158-64. doi: 10.1016/j.ajpath.2012.06.042. Epub 2012 Aug 4.

24.

The biochemistry and biology of the atypical chemokine receptors.

Graham GJ, Locati M, Mantovani A, Rot A, Thelen M.

Immunol Lett. 2012 Jul 30;145(1-2):30-8. doi: 10.1016/j.imlet.2012.04.004. Review.

PMID:
22698181
25.

Recovery of partially occluded objects by applying compressive Fresnel holography.

Rivenson Y, Rot A, Balber S, Stern A, Rosen J.

Opt Lett. 2012 May 15;37(10):1757-9. doi: 10.1364/OL.37.001757.

PMID:
22627561
26.

Resistant ticks inhibit Metarhizium infection prior to haemocoel invasion by reducing fungal viability on the cuticle surface.

Ment D, Churchill AC, Gindin G, Belausov E, Glazer I, Rehner SA, Rot A, Donzelli BG, Samish M.

Environ Microbiol. 2012 Jun;14(6):1570-83. doi: 10.1111/j.1462-2920.2012.02747.x. Epub 2012 Apr 17.

PMID:
22507442
27.

High-affinity IgE receptors on dendritic cells exacerbate Th2-dependent inflammation.

Sallmann E, Reininger B, Brandt S, Duschek N, Hoflehner E, Garner-Spitzer E, Platzer B, Dehlink E, Hammer M, Holcmann M, Oettgen HC, Wiedermann U, Sibilia M, Fiebiger E, Rot A, Maurer D.

J Immunol. 2011 Jul 1;187(1):164-71. doi: 10.4049/jimmunol.1003392. Epub 2011 May 27.

28.

Atypical chemokine receptors.

Ulvmar MH, Hub E, Rot A.

Exp Cell Res. 2011 Mar 10;317(5):556-68. doi: 10.1016/j.yexcr.2011.01.012. Epub 2011 Jan 25. Review.

29.

Novel technique for quantifying adhesion of Metarhizium anisopliae conidia to the tick cuticle.

Ment D, Gindin G, Rot A, Soroker V, Glazer I, Barel S, Samish M.

Appl Environ Microbiol. 2010 Jun;76(11):3521-8. doi: 10.1128/AEM.02596-09. Epub 2010 Apr 2.

30.

CXCR7 functions as a scavenger for CXCL12 and CXCL11.

Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes HG, Rot A, Thelen M.

PLoS One. 2010 Feb 11;5(2):e9175. doi: 10.1371/journal.pone.0009175.

31.

Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients.

Madigan J, Freeman DJ, Menzies F, Forrow S, Nelson SM, Young A, Sharkey A, Moffett A, Graham GJ, Greer IA, Rot A, Nibbs RJ.

J Immunol. 2010 Mar 15;184(6):3202-12. doi: 10.4049/jimmunol.0902118. Epub 2010 Feb 10.

32.

Chemokine patterning by glycosaminoglycans and interceptors.

Rot A.

Front Biosci (Landmark Ed). 2010 Jan 1;15:645-60. Review.

PMID:
20036838
33.

Metarhizium anisopliae conidial responses to lipids from tick cuticle and tick mammalian host surface.

Ment D, Gindin G, Soroker V, Glazer I, Rot A, Samish M.

J Invertebr Pathol. 2010 Feb;103(2):132-9. doi: 10.1016/j.jip.2009.12.010. Epub 2009 Dec 29.

PMID:
20036669
34.

CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells.

Eller K, Weber T, Pruenster M, Wolf AM, Mayer G, Rosenkranz AR, Rot A.

J Am Soc Nephrol. 2010 Jan;21(1):42-52. doi: 10.1681/ASN.2009020133. Epub 2009 Nov 16.

35.

Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines.

Vielhauer V, Allam R, Lindenmeyer MT, Cohen CD, Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ, Anders HJ, Pruenster M, Rot A, Schlöndorff D, Segerer S.

Am J Pathol. 2009 Jul;175(1):119-31. doi: 10.2353/ajpath.2009.080590. Epub 2009 Jun 4.

36.
37.

Chapter 9 the duffy antigen receptor for chemokines.

Rot A, Horuk R.

Methods Enzymol. 2009;461:191-206. doi: 10.1016/S0076-6879(09)05409-3.

PMID:
19480920
38.

1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype.

Széles L, Keresztes G, Töröcsik D, Balajthy Z, Krenács L, Póliska S, Steinmeyer A, Zuegel U, Pruenster M, Rot A, Nagy L.

J Immunol. 2009 Feb 15;182(4):2074-83. doi: 10.4049/jimmunol.0803345.

39.

The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity.

Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ, Segerer S, Nibbs RJ, Rot A.

Nat Immunol. 2009 Jan;10(1):101-8. doi: 10.1038/ni.1675. Epub 2008 Dec 7. Erratum in: Nat Immunol. 2009 Feb;10(2):223.

40.

Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1.

McKimmie CS, Fraser AR, Hansell C, Gutiérrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M, Carreno P, Pruenster M, Chu CC, Lombardi G, Halsey C, McInnes IB, Liew FY, Nibbs RJ, Graham GJ.

J Immunol. 2008 Dec 1;181(11):8171-81.

41.

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.

Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T, Voshol H, Meingassner JG, Mao X, Werner G, Rot A, Carballido JM.

Nat Immunol. 2008 Nov;9(11):1261-9. doi: 10.1038/ni.1657. Epub 2008 Sep 28.

PMID:
18820681
42.

Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1.

McKimmie CS, Fraser AR, Hansell C, Gutiérrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M, Carreno P, Pruenster M, Chu CC, Lombardi G, Halsey C, McInnes IB, Liew FY, Nibbs RJ, Graham GJ.

J Immunol. 2008 Sep 1;181(5):3353-63. Erratum in: J Immunol. 2008 Dec 1;181(11):8170. Corrected and republished in: J Immunol. 2008 Dec 1;181(11):8171-81.

43.

Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: comparison with human.

Chamberlain G, Wright K, Rot A, Ashton B, Middleton J.

PLoS One. 2008 Aug 13;3(8):e2934. doi: 10.1371/journal.pone.0002934.

44.

CCR7 and its ligands: balancing immunity and tolerance.

Förster R, Davalos-Misslitz AC, Rot A.

Nat Rev Immunol. 2008 May;8(5):362-71. doi: 10.1038/nri2297. Review.

PMID:
18379575
45.

Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response.

Koehn J, Huesken D, Jaritz M, Rot A, Zurini M, Dwertmann A, Beutler B, Korthäuer U.

Hum Immunol. 2007 Nov;68(11):871-8. Epub 2007 Sep 24.

PMID:
18082565
46.

Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients.

Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D.

J Immunol. 2007 Sep 15;179(6):4272-82.

47.

Chemokines at large: in-vivo mechanisms of their transport, presentation and clearance.

Colditz IG, Schneider MA, Pruenster M, Rot A.

Thromb Haemost. 2007 May;97(5):688-93. Review.

PMID:
17479178
48.

CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells.

Schneider MA, Meingassner JG, Lipp M, Moore HD, Rot A.

J Exp Med. 2007 Apr 16;204(4):735-45. Epub 2007 Mar 19.

49.

Throwing light on DARC.

Pruenster M, Rot A.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1005-8. Review.

PMID:
17073738
50.

IL-12 instructs skin homing of human Th2 cells.

Biedermann T, Lametschwandtner G, Tangemann K, Kund J, Hinteregger S, Carballido-Perrig N, Rot A, Schwärzler C, Carballido JM.

J Immunol. 2006 Sep 15;177(6):3763-70.

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