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Items: 36

1.

PD-1 of Sigmodon hispidus: Gene identification, characterization and preliminary evaluation of expression in inactivated RSV vaccine-induced enhanced respiratory disease.

Muralidharan A, Larocque L, Russell M, Creskey M, Li C, Chen W, Van Domselaar G, Cao J, Cyr T, Rosu-Myles M, Wang L, Li X.

Sci Rep. 2019 Aug 12;9(1):11638. doi: 10.1038/s41598-019-48225-x.

2.

Chitosan alters inactivated respiratory syncytial virus vaccine elicited immune responses without affecting lung histopathology in mice.

Muralidharan A, Russell MS, Larocque L, Gravel C, Sauvé S, Chen Z, Li C, Chen W, Cyr T, Rosu-Myles M, Wang L, Li X.

Vaccine. 2019 Jul 9;37(30):4031-4039. doi: 10.1016/j.vaccine.2019.06.003. Epub 2019 Jun 8.

PMID:
31186190
3.

Unveiling Integrated Functional Pathways Leading to Enhanced Respiratory Disease Associated With Inactivated Respiratory Syncytial Viral Vaccine.

Russell MS, Creskey M, Muralidharan A, Li C, Gao J, Chen W, Larocque L, Lavoie JR, Farnsworth A, Rosu-Myles M, Hashem AM, Yauk CL, Cao J, Van Domselaar G, Cyr T, Li X.

Front Immunol. 2019 Mar 29;10:597. doi: 10.3389/fimmu.2019.00597. eCollection 2019.

4.

Targeting CD40 enhances antibody- and CD8-mediated protection against respiratory syncytial virus infection.

Muralidharan A, Russell M, Larocque L, Gravel C, Li C, Chen W, Cyr T, Lavoie JR, Farnsworth A, Rosu-Myles M, Wang L, Li X.

Sci Rep. 2018 Nov 9;8(1):16648. doi: 10.1038/s41598-018-34999-z.

5.

Bone marrow mesenchymal stem/stromal cells from risk-stratified acute myeloid leukemia patients are anti-inflammatory in in vivo preclinical models of hematopoietic reconstitution and severe colitis.

de la Guardia RD, Lopez-Millan B, Roca-Ho H, Bueno C, Gutiérrez-Agüera F, Fuster JL, Anguita E, Zanetti SR, Vives S, Nomdedeu J, Sackstein R, Lavoie J, Gónzalez-Rey E, Delgado M, Rosu-Myles M, Menendez P.

Haematologica. 2019 Feb;104(2):e54-e58. doi: 10.3324/haematol.2018.196568. Epub 2018 Sep 20. No abstract available.

6.

Micro-RNA Profiling of Exosomes from Marrow-Derived Mesenchymal Stromal Cells in Patients with Acute Myeloid Leukemia: Implications in Leukemogenesis.

Barrera-Ramirez J, Lavoie JR, Maganti HB, Stanford WL, Ito C, Sabloff M, Brand M, Rosu-Myles M, Le Y, Allan DS.

Stem Cell Rev Rep. 2017 Dec;13(6):817-825. doi: 10.1007/s12015-017-9762-0.

7.

Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes.

Diaz de la Guardia R, Lopez-Millan B, Lavoie JR, Bueno C, Castaño J, Gómez-Casares M, Vives S, Palomo L, Juan M, Delgado J, Blanco ML, Nomdedeu J, Chaparro A, Fuster JL, Anguita E, Rosu-Myles M, Menéndez P.

Stem Cell Reports. 2017 Jun 6;8(6):1573-1586. doi: 10.1016/j.stemcr.2017.04.019. Epub 2017 May 18.

8.

Therapeutic effect of the immunomodulatory drug lenalidomide, but not pomalidomide, in experimental models of rheumatoid arthritis and inflammatory bowel disease.

Lopez-Millan B, Diaz de la Guardia R, Roca-Ho H, García-Herrero CM, Lavoie JR, Rosu-Myles M, Gonzalez-Rey E, O'Valle F, Criado G, Delgado M, Menendez P.

Exp Mol Med. 2017 Feb 3;49(2):e290. doi: 10.1038/emm.2016.143.

9.

Brief Report: Elastin Microfibril Interface 1 and Integrin-Linked Protein Kinase Are Novel Markers of Islet Regenerative Function in Human Multipotent Mesenchymal Stromal Cells.

Lavoie JR, Creskey MM, Muradia G, Bell GI, Sherman SE, Gao J, Stewart DJ, Cyr TD, Hess DA, Rosu-Myles M.

Stem Cells. 2016 Aug;34(8):2249-55. doi: 10.1002/stem.2385. Epub 2016 May 19.

10.

Adipogenic Mesenchymal Stromal Cells from Bone Marrow and Their Hematopoietic Supportive Role: Towards Understanding the Permissive Marrow Microenvironment in Acute Myeloid Leukemia.

Le Y, Fraineau S, Chandran P, Sabloff M, Brand M, Lavoie JR, Gagne R, Rosu-Myles M, Yauk CL, Richardson RB, Allan DS.

Stem Cell Rev Rep. 2016 Apr;12(2):235-44. doi: 10.1007/s12015-015-9639-z.

PMID:
26649729
11.

Regulatory Oversight of Cell and Gene Therapy Products in Canada.

Ridgway A, Agbanyo F, Wang J, Rosu-Myles M.

Adv Exp Med Biol. 2015;871:49-71. doi: 10.1007/978-3-319-18618-4_3. Review.

PMID:
26374212
12.

Comparison of orthogonal chromatographic and lectin-affinity microarray methods for glycan profiling of a therapeutic monoclonal antibody.

Cook MC, Kaldas SJ, Muradia G, Rosu-Myles M, Kunkel JP.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 1;997:162-78. doi: 10.1016/j.jchromb.2015.05.035. Epub 2015 Jun 9.

PMID:
26114652
13.

Mesenchymal stromal cells from patients with acute myeloid leukemia have altered capacity to expand differentiated hematopoietic progenitors.

Chandran P, Le Y, Li Y, Sabloff M, Mehic J, Rosu-Myles M, Allan DS.

Leuk Res. 2015 Apr;39(4):486-93. doi: 10.1016/j.leukres.2015.01.013. Epub 2015 Feb 2.

PMID:
25703353
14.

Human bone marrow stromal cells lose immunosuppressive and anti-inflammatory properties upon oncogenic transformation.

Rodriguez R, Rosu-Myles M, Aráuzo-Bravo M, Horrillo A, Pan Q, Gonzalez-Rey E, Delgado M, Menendez P.

Stem Cell Reports. 2014 Oct 14;3(4):606-19. doi: 10.1016/j.stemcr.2014.08.005. Epub 2014 Sep 11.

15.

CD40 ligand preferentially modulates immune response and enhances protection against influenza virus.

Hashem AM, Gravel C, Chen Z, Yi Y, Tocchi M, Jaentschke B, Fan X, Li C, Rosu-Myles M, Pereboev A, He R, Wang J, Li X.

J Immunol. 2014 Jul 15;193(2):722-34. doi: 10.4049/jimmunol.1300093. Epub 2014 Jun 13.

16.

Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease.

Bueno C, Roldan M, Anguita E, Romero-Moya D, Martín-Antonio B, Rosu-Myles M, del Cañizo C, Campos F, García R, Gómez-Casares M, Fuster JL, Jurado M, Delgado M, Menendez P.

Haematologica. 2014 Jul;99(7):1168-75. doi: 10.3324/haematol.2014.103580. Epub 2014 Apr 11.

17.

Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells.

Rubio R, Abarrategi A, Garcia-Castro J, Martinez-Cruzado L, Suarez C, Tornin J, Santos L, Astudillo A, Colmenero I, Mulero F, Rosu-Myles M, Menendez P, Rodriguez R.

Stem Cells. 2014 May;32(5):1136-48. doi: 10.1002/stem.1647.

18.

Expression of FUS-CHOP fusion protein in immortalized/transformed human mesenchymal stem cells drives mixoid liposarcoma formation.

Rodriguez R, Tornin J, Suarez C, Astudillo A, Rubio R, Yauk C, Williams A, Rosu-Myles M, Funes JM, Boshoff C, Menendez P.

Stem Cells. 2013 Oct;31(10):2061-72. doi: 10.1002/stem.1472.

19.

Uncovering the secretes of mesenchymal stem cells.

Lavoie JR, Rosu-Myles M.

Biochimie. 2013 Dec;95(12):2212-21. doi: 10.1016/j.biochi.2013.06.017. Epub 2013 Jun 28. Review.

PMID:
23810910
20.

The role of tumor suppressor p15Ink4b in the regulation of hematopoietic progenitor cell fate.

Humeniuk R, Rosu-Myles M, Fares J, Koller R, Bies J, Wolff L.

Blood Cancer J. 2013 Jan;3(1):e99. doi: 10.1038/bcj.2012.44. Epub 2013 Jan 4.

21.

The globoseries glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo.

Rosu-Myles M, McCully J, Fair J, Mehic J, Menendez P, Rodriguez R, Westwood C.

Stem Cells Dev. 2013 May 1;22(9):1387-97. doi: 10.1089/scd.2012.0547. Epub 2013 Jan 18.

PMID:
23330736
22.

The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development.

Rubio R, Gutierrez-Aranda I, Sáez-Castillo AI, Labarga A, Rosu-Myles M, Gonzalez-Garcia S, Toribio ML, Menendez P, Rodriguez R.

Oncogene. 2013 Oct 10;32(41):4970-80. doi: 10.1038/onc.2012.507. Epub 2012 Dec 10.

PMID:
23222711
23.

Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells.

Rosu-Myles M, She YM, Fair J, Muradia G, Mehic J, Menendez P, Prasad SS, Cyr TD.

PLoS One. 2012;7(6):e38954. doi: 10.1371/journal.pone.0038954. Epub 2012 Jun 13.

24.

Subcutaneous immunization with recombinant adenovirus expressing influenza A nucleoprotein protects mice against lethal viral challenge.

Hashem A, Jaentschke B, Gravel C, Tocchi M, Doyle T, Rosu-Myles M, He R, Li X.

Hum Vaccin Immunother. 2012 Apr;8(4):425-30. doi: 10.4161/hv.19109. Epub 2012 Feb 28.

PMID:
22370512
25.

Quantification of protein isoforms in mesenchymal stem cells by reductive dimethylation of lysines in intact proteins.

She YM, Rosu-Myles M, Walrond L, Cyr TD.

Proteomics. 2012 Feb;12(3):369-79. doi: 10.1002/pmic.201100308. Epub 2012 Jan 13.

26.

The mouse mammary microenvironment redirects mesoderm-derived bone marrow cells to a mammary epithelial progenitor cell fate.

Boulanger CA, Bruno RD, Rosu-Myles M, Smith GH.

Stem Cells Dev. 2012 Apr 10;21(6):948-54. doi: 10.1089/scd.2011.0148. Epub 2011 Jul 18.

27.

Non-multipotent stroma inhibit the proliferation and differentiation of mesenchymal stromal cells in vitro.

Rosu-Myles M, Fair J, Pearce N, Mehic J.

Cytotherapy. 2010 Oct;12(6):818-30. doi: 10.3109/14653249.2010.501785.

PMID:
20662608
28.

Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia.

Bies J, Sramko M, Fares J, Rosu-Myles M, Zhang S, Koller R, Wolff L.

Blood. 2010 Aug 12;116(6):979-87. doi: 10.1182/blood-2009-08-238360. Epub 2010 May 10.

29.

p15Ink4b: dual function in myelopoiesis and inactivation in myeloid disease.

Rosu-Myles M, Wolff L.

Blood Cells Mol Dis. 2008 May-Jun;40(3):406-9. Epub 2007 Oct 29. Review.

PMID:
18029205
30.

Loss of the tumor suppressor p15Ink4b enhances myeloid progenitor formation from common myeloid progenitors.

Rosu-Myles M, Taylor BJ, Wolff L.

Exp Hematol. 2007 Mar;35(3):394-406.

PMID:
17309820
31.

A unique population of bone marrow cells migrates to skeletal muscle via hepatocyte growth factor/c-met axis.

Rosu-Myles M, Stewart E, Trowbridge J, Ito CY, Zandstra P, Bhatia M.

J Cell Sci. 2005 Oct 1;118(Pt 19):4343-52. Epub 2005 Sep 6.

32.
33.

Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor.

Hess DA, Levac KD, Karanu FN, Rosu-Myles M, White MJ, Gallacher L, Murdoch B, Keeney M, Ottowski P, Foley R, Chin-Yee I, Bhatia M.

Blood. 2002 Aug 1;100(3):869-78.

34.

The human hematopoietic stem cell compartment is heterogeneous for CXCR4 expression.

Rosu-Myles M, Gallacher L, Murdoch B, Hess DA, Keeney M, Kelvin D, Dale L, Ferguson SS, Wu D, Fellows F, Bhatia M.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14626-31.

35.

Characterization of chemokine receptors expressed in primitive blood cells during human hematopoietic ontogeny.

Rosu-Myles M, Khandaker M, Wu DM, Keeney M, Foley SR, Howson-Jan K, Yee IC, Fellows F, Kelvin D, Bhatia M.

Stem Cells. 2000;18(5):374-81.

36.

Rational design of a more stable yeast iso-1-cytochrome c.

Lett CM, Rosu-Myles MD, Frey HE, Guillemette JG.

Biochim Biophys Acta. 1999 Jun 15;1432(1):40-8.

PMID:
10366726

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