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Items: 1 to 50 of 144

1.

Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts.

Galinski S, Wichert SP, Rossner MJ, Wehr MC.

Sci Rep. 2018 May 25;8(1):8137. doi: 10.1038/s41598-018-26401-9.

2.

Repurposing: Der schnellere Weg vom Target zur klinisch anwendbaren Substanz.

Rossner M.

Drug Res (Stuttg). 2017 Nov;67(S 01):S16. doi: 10.1055/s-0043-116531. Epub 2017 Oct 25. German. No abstract available.

PMID:
29069679
Free Article
3.

Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice.

Wehr MC, Hinrichs W, Brzózka MM, Unterbarnscheidt T, Herholt A, Wintgens JP, Papiol S, Soto-Bernardini MC, Kravchenko M, Zhang M, Nave KA, Wichert SP, Falkai P, Zhang W, Schwab MH, Rossner MJ.

EMBO Mol Med. 2017 Oct;9(10):1448-1462. doi: 10.15252/emmm.201707691.

4.

Polygenic risk has an impact on the structural plasticity of hippocampal subfields during aerobic exercise combined with cognitive remediation in multi-episode schizophrenia.

Papiol S, Popovic D, Keeser D, Hasan A, Schneider-Axmann T, Degenhardt F, Rossner MJ, Bickeböller H, Schmitt A, Falkai P, Malchow B.

Transl Psychiatry. 2017 Jun 27;7(6):e1159. doi: 10.1038/tp.2017.131.

5.

Characterizing Dynamic Protein-Protein Interactions Using the Genetically Encoded Split Biosensor Assay Technique Split TEV.

Wintgens JP, Rossner MJ, Wehr MC.

Methods Mol Biol. 2017;1596:219-238. doi: 10.1007/978-1-4939-6940-1_14.

PMID:
28293890
6.

Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells.

Kreslavsky T, Vilagos B, Tagoh H, Poliakova DK, Schwickert TA, Wöhner M, Jaritz M, Weiss S, Taneja R, Rossner MJ, Busslinger M.

Nat Immunol. 2017 Apr;18(4):442-455. doi: 10.1038/ni.3694. Epub 2017 Feb 27.

7.

A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination.

Goebbels S, Wieser GL, Pieper A, Spitzer S, Weege B, Yan K, Edgar JM, Yagensky O, Wichert SP, Agarwal A, Karram K, Renier N, Tessier-Lavigne M, Rossner MJ, Káradóttir RT, Nave KA.

Nat Neurosci. 2017 Jan;20(1):10-15. doi: 10.1038/nn.4425. Epub 2016 Oct 24.

PMID:
27775720
8.

Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia, part III: Molecular mechanisms.

Schmitt A, Martins-de-Souza D, Akbarian S, Cassoli JS, Ehrenreich H, Fischer A, Fonteh A, Gattaz WF, Gawlik M, Gerlach M, Grünblatt E, Halene T, Hasan A, Hashimoto K, Kim YK, Kirchner SK, Kornhuber J, Kraus TFJ, Malchow B, Nascimento JM, Rossner M, Schwarz M, Steiner J, Talib L, Thibaut F, Riederer P, Falkai P; Members of the WFSBP Task Force on Biological Markers.

World J Biol Psychiatry. 2017 Aug;18(5):330-356. doi: 10.1080/15622975.2016.1224929. Epub 2016 Oct 26. Review.

PMID:
27782767
9.

Age-related myelin degradation burdens the clearance function of microglia during aging.

Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, Edinger AL, Jung S, Rossner MJ, Simons M.

Nat Neurosci. 2016 Aug;19(8):995-8. doi: 10.1038/nn.4325. Epub 2016 Jun 13.

PMID:
27294511
10.

Molecular Signatures of Psychosocial Stress and Cognition Are Modulated by Chronic Lithium Treatment.

Brzózka MM, Havemann-Reinecke U, Wichert SP, Falkai P, Rossner MJ.

Schizophr Bull. 2016 Jul;42 Suppl 1:S22-33. doi: 10.1093/schbul/sbv194. Epub 2015 Dec 28.

11.

OSO paradigm--A rapid behavioral screening method for acute psychosocial stress reactivity in mice.

Brzózka MM, Unterbarnscheidt T, Schwab MH, Rossner MJ.

Neuroscience. 2016 Feb 9;314:1-11. doi: 10.1016/j.neuroscience.2015.11.043. Epub 2015 Nov 25.

PMID:
26628400
12.

Split protein biosensor assays in molecular pharmacological studies.

Wehr MC, Rossner MJ.

Drug Discov Today. 2016 Mar;21(3):415-29. doi: 10.1016/j.drudis.2015.11.004. Epub 2015 Nov 21. Review.

PMID:
26610415
13.

Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.

Fleck D, Voss M, Brankatschk B, Giudici C, Hampel H, Schwenk B, Edbauer D, Fukumori A, Steiner H, Kremmer E, Haug-Kröper M, Rossner MJ, Fluhrer R, Willem M, Haass C.

J Biol Chem. 2016 Jan 1;291(1):318-33. doi: 10.1074/jbc.M115.697995. Epub 2015 Nov 16.

14.

Cell type- and brain region-resolved mouse brain proteome.

Sharma K, Schmitt S, Bergner CG, Tyanova S, Kannaiyan N, Manrique-Hoyos N, Kongi K, Cantuti L, Hanisch UK, Philips MA, Rossner MJ, Mann M, Simons M.

Nat Neurosci. 2015 Dec;18(12):1819-31. doi: 10.1038/nn.4160. Epub 2015 Nov 2.

PMID:
26523646
15.

Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53.

Herold S, Kumar P, Wichert SP, Kretzschmar B, Bähr M, Rossner MJ, Hein K.

PLoS One. 2015 Oct 1;10(10):e0138852. doi: 10.1371/journal.pone.0138852. eCollection 2015.

16.

Tcf4 transgenic female mice display delayed adaptation in an auditory latent inhibition paradigm.

Brzózka MM, Rossner MJ, de Hoz L.

Eur Arch Psychiatry Clin Neurosci. 2016 Sep;266(6):505-12. doi: 10.1007/s00406-015-0643-8. Epub 2015 Sep 24.

PMID:
26404636
17.

Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex.

Shahmoradi A, Radyushkin K, Rossner MJ.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3582-9. doi: 10.1073/pnas.1423989112. Epub 2015 Jun 22.

18.

Kraepelin revisited: schizophrenia from degeneration to failed regeneration.

Falkai P, Rossner MJ, Schulze TG, Hasan A, Brzózka MM, Malchow B, Honer WG, Schmitt A.

Mol Psychiatry. 2015 Jun;20(6):671-6. doi: 10.1038/mp.2015.35. Epub 2015 Mar 31. Review.

PMID:
25824303
19.

Monitoring G protein-coupled receptor activation using the protein fragment complementation technique split TEV.

Wehr MC, Galinski S, Rossner MJ.

Methods Mol Biol. 2015;1272:107-18. doi: 10.1007/978-1-4939-2336-6_8.

PMID:
25563180
20.

Mice lacking the circadian modulators SHARP1 and SHARP2 display altered sleep and mixed state endophenotypes of psychiatric disorders.

Baier PC, Brzózka MM, Shahmoradi A, Reinecke L, Kroos C, Wichert SP, Oster H, Wehr MC, Taneja R, Hirrlinger J, Rossner MJ.

PLoS One. 2014 Oct 23;9(10):e110310. doi: 10.1371/journal.pone.0110310. eCollection 2014.

21.

Data calibration and reduction allows to visualize behavioural profiles of psychosocial influences in mice towards clinical domains.

Badowska DM, Brzózka MM, Chowdhury A, Malzahn D, Rossner MJ.

Eur Arch Psychiatry Clin Neurosci. 2015 Sep;265(6):483-96. doi: 10.1007/s00406-014-0532-6. Epub 2014 Sep 19.

PMID:
25236183
22.

Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.

Hsia HE, Kumar R, Luca R, Takeda M, Courchet J, Nakashima J, Wu S, Goebbels S, An W, Eickholt BJ, Polleux F, Rotin D, Wu H, Rossner MJ, Bagni C, Rhee JS, Brose N, Kawabe H.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13205-10. doi: 10.1073/pnas.1400737111. Epub 2014 Aug 25.

23.

Dysregulated expression of neuregulin-1 by cortical pyramidal neurons disrupts synaptic plasticity.

Agarwal A, Zhang M, Trembak-Duff I, Unterbarnscheidt T, Radyushkin K, Dibaj P, Martins de Souza D, Boretius S, Brzózka MM, Steffens H, Berning S, Teng Z, Gummert MN, Tantra M, Guest PC, Willig KI, Frahm J, Hell SW, Bahn S, Rossner MJ, Nave KA, Ehrenreich H, Zhang W, Schwab MH.

Cell Rep. 2014 Aug 21;8(4):1130-45. doi: 10.1016/j.celrep.2014.07.026. Epub 2014 Aug 14.

24.

Thy1.2 driven expression of transgenic His₆-SUMO2 in the brain of mice alters a restricted set of genes.

Rossner MJ, Tirard M.

Brain Res. 2014 Aug 5;1575:1-11. doi: 10.1016/j.brainres.2014.05.036. Epub 2014 Jun 2.

PMID:
24887641
25.

Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model.

Prukop T, Epplen DB, Nientiedt T, Wichert SP, Fledrich R, Stassart RM, Rossner MJ, Edgar JM, Werner HB, Nave KA, Sereda MW.

Am J Hum Genet. 2014 Apr 3;94(4):533-46. doi: 10.1016/j.ajhg.2014.03.001. Epub 2014 Mar 27.

26.

Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective.

Quednow BB, Brzózka MM, Rossner MJ.

Cell Mol Life Sci. 2014 Aug;71(15):2815-35. doi: 10.1007/s00018-013-1553-4. Epub 2014 Jan 12. Review.

PMID:
24413739
27.

Nanoscopy of filamentous actin in cortical dendrites of a living mouse.

Willig KI, Steffens H, Gregor C, Herholt A, Rossner MJ, Hell SW.

Biophys J. 2014 Jan 7;106(1):L01-3. doi: 10.1016/j.bpj.2013.11.1119.

28.

Sharp-1 regulates TGF-β signaling and skeletal muscle regeneration.

Acharjee S, Chung TK, Gopinadhan S, Shankar SR, Wang Y, Li L, Vercherat C, Gulbagci NT, Rossner M, Taneja R.

J Cell Sci. 2014 Feb 1;127(Pt 3):599-608. doi: 10.1242/jcs.136648. Epub 2013 Dec 19.

29.

Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination.

Syed YA, Baer A, Hofer MP, González GA, Rundle J, Myrta S, Huang JK, Zhao C, Rossner MJ, Trotter MW, Lubec G, Franklin RJ, Kotter MR.

EMBO Mol Med. 2013 Dec;5(12):1918-34. doi: 10.1002/emmm.201303123. Epub 2013 Oct 21.

30.

The multispecific thyroid hormone transporter OATP1C1 mediates cell-specific sulforhodamine 101-labeling of hippocampal astrocytes.

Schnell C, Shahmoradi A, Wichert SP, Mayerl S, Hagos Y, Heuer H, Rossner MJ, Hülsmann S.

Brain Struct Funct. 2015 Jan;220(1):193-203. doi: 10.1007/s00429-013-0645-0. Epub 2013 Oct 16.

31.

New mandates? No problem for The Rockefeller University Press.

Rossner M.

J Cell Biol. 2013 Apr 1;201(1):7-9. doi: 10.1083/jcb.201303016. Epub 2013 Mar 8. No abstract available.

32.

New mandates? No problem for The Rockefeller University Press.

Rossner M.

J Gen Physiol. 2013 Apr;141(4):397-9. doi: 10.1085/jgp.201310987. Epub 2013 Mar 8.

33.

New mandates? No problem for The Rockefeller University Press.

Rossner M.

J Exp Med. 2013 Apr 8;210(4):643-5. doi: 10.1084/jem.20130457. Epub 2013 Mar 8.

34.

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila.

Wehr MC, Holder MV, Gailite I, Saunders RE, Maile TM, Ciirdaeva E, Instrell R, Jiang M, Howell M, Rossner MJ, Tapon N.

Nat Cell Biol. 2013 Jan;15(1):61-71.

35.

Tissue-specific interaction of Per1/2 and Dec2 in the regulation of fibroblast circadian rhythms.

Tsang AH, Sánchez-Moreno C, Bode B, Rossner MJ, Garaulet M, Oster H.

J Biol Rhythms. 2012 Dec;27(6):478-89. doi: 10.1177/0748730412462838.

PMID:
23223373
36.

Common variant at 16p11.2 conferring risk of psychosis.

Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen T, Ingason A, Pirinen M, Strengman E; GROUP, Hougaard DM, Orntoft T, Didriksen M, Hollegaard MV, Nordentoft M, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Etain B, Bellivier F, Méary A, Schürhoff F, Szoke A, Ribolsi M, Magni V, Siracusano A, Sperling S, Rossner M, Christiansen C, Kiemeney LA, Franke B, van den Berg LH, Veldink J, Curran S, Bolton P, Poot M, Staal W, Rehnstrom K, Kilpinen H, Freitag CM, Meyer J, Magnusson P, Saemundsen E, Martsenkovsky I, Bikshaieva I, Martsenkovska I, Vashchenko O, Raleva M, Paketchieva K, Stefanovski B, Durmishi N, Pejovic Milovancevic M, Lecic Tosevski D, Silagadze T, Naneishvili N, Mikeladze N, Surguladze S, Vincent JB, Farmer A, Mitchell PB, Wright A, Schofield PR, Fullerton JM, Montgomery GW, Martin NG, Rubino IA, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Terenius L, Jönsson EG, Bakker S, van Os J, Jablensky A, Leboyer M, Bramon E, Powell J, Murray R, Corvin A, Gill M, Morris D, O'Neill FA, Kendler K, Riley B; Wellcome Trust Case Control Consortium 2, Craddock N, Owen MJ, O'Donovan MC, Thorsteinsdottir U, Kong A, Ehrenreich H, Carracedo A, Golimbet V, Andreassen OA, Børglum AD, Mors O, Mortensen PB, Werge T, Ophoff RA, Nöthen MM, Rietschel M, Cichon S, Ruggeri M, Tosato S, Palotie A, St Clair D, Rujescu D, Collier DA, Stefansson H, Stefansson K.

Mol Psychiatry. 2014 Jan;19(1):108-14. doi: 10.1038/mp.2012.157. Epub 2012 Nov 20.

37.

Communication of scientific information: is it time to reassess?

Rifai N, Sack J, Keller MA, Acharya A, Bourne PE, Rossner M, Wills S.

Clin Chem. 2013 Apr;59(4):604-11. doi: 10.1373/clinchem.2012.194738. Epub 2012 Nov 16. No abstract available.

38.

Deficits in trace fear memory in a mouse model of the schizophrenia risk gene TCF4.

Brzózka MM, Rossner MJ.

Behav Brain Res. 2013 Jan 15;237:348-56. doi: 10.1016/j.bbr.2012.10.001. Epub 2012 Oct 13.

PMID:
23069005
39.

Digital Imaging and Communications in Medicine (DICOM) as standard in digital pathology.

Kalinski T, Zwönitzer R, Roßner M, Hofmann H, Roessner A, Guenther T.

Histopathology. 2012 Jul;61(1):132-4. doi: 10.1111/j.1365-2559.2012.04243.x. Epub 2012 May 2. No abstract available.

PMID:
22551421
40.

Involvement of doublecortin-expressing cells in the arcuate nucleus in body weight regulation.

Werner L, Müller-Fielitz H, Ritzal M, Werner T, Rossner M, Schwaninger M.

Endocrinology. 2012 Jun;153(6):2655-64. doi: 10.1210/en.2011-1760. Epub 2012 Apr 4.

PMID:
22492306
41.

Structural synaptic elements are differentially regulated in superior temporal cortex of schizophrenia patients.

Schmitt A, Leonardi-Essmann F, Durrenberger PF, Wichert SP, Spanagel R, Arzberger T, Kretzschmar H, Zink M, Herrera-Marschitz M, Reynolds R, Rossner MJ, Falkai P, Gebicke-Haerter PJ.

Eur Arch Psychiatry Clin Neurosci. 2012 Oct;262(7):565-77. doi: 10.1007/s00406-012-0306-y. Epub 2012 Mar 23.

42.

Virtual dermatohistopathology at http://www.pathowiki.org.

Roßner M, Roßner F, Zwönitzer R, Hofmann H, Sterry W, Kalinski T.

J Dtsch Dermatol Ges. 2012 Apr;10(4):245-50. doi: 10.1111/j.1610-0387.2012.07813.x. Review. English, German.

PMID:
22435687
43.

Regulation of the EGF transcriptional response by endocytic sorting.

Brankatschk B, Wichert SP, Johnson SD, Schaad O, Rossner MJ, Gruenberg J.

Sci Signal. 2012 Mar 13;5(215):ra21. doi: 10.1126/scisignal.2002351.

44.

[Pathowiki. A free expert database for pathology].

Rossner M, Rossner F, Zwönitzer R, Süss T, Hofmann H, Roessner A, Kalinski T.

Pathologe. 2012 Mar;33(2):124-8. doi: 10.1007/s00292-011-1550-z. German.

PMID:
22315102
45.

Integrated measurement of split TEV and cis-regulatory assays using EXT encoded reporter libraries.

Botvinik A, Rossner MJ.

Methods Mol Biol. 2012;812:309-23. doi: 10.1007/978-1-61779-455-1_19.

PMID:
22218869
46.

Genetic interaction of Per1 and Dec1/2 in the regulation of circadian locomotor activity.

Bode B, Shahmoradi A, Taneja R, Rossner MJ, Oster H.

J Biol Rhythms. 2011 Dec;26(6):530-40. doi: 10.1177/0748730411419782. Erratum in: J Biol Rhythms. 2012 Apr;27(2):180. Taneja, Reshma [added].

PMID:
22215611
47.

A rat model of Charcot-Marie-Tooth disease 1A recapitulates disease variability and supplies biomarkers of axonal loss in patients.

Fledrich R, Schlotter-Weigel B, Schnizer TJ, Wichert SP, Stassart RM, Meyer zu Hörste G, Klink A, Weiss BG, Haag U, Walter MC, Rautenstrauss B, Paulus W, Rossner MJ, Sereda MW.

Brain. 2012 Jan;135(Pt 1):72-87. doi: 10.1093/brain/awr322. Epub 2011 Dec 20.

PMID:
22189569
48.

Advanced light-entrained activity onsets and restored free-running suprachiasmatic nucleus circadian rhythms in per2/dec mutant mice.

Bode B, Taneja R, Rossner MJ, Oster H.

Chronobiol Int. 2011 Nov;28(9):737-50. doi: 10.3109/07420528.2011.607374. Erratum in: Chronobiol Int. 2012 Apr;29(3):377. Taneja, Reshma [added].

PMID:
22080784
49.

Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.

Velanac V, Unterbarnscheidt T, Hinrichs W, Gummert MN, Fischer TM, Rossner MJ, Trimarco A, Brivio V, Taveggia C, Willem M, Haass C, Möbius W, Nave KA, Schwab MH.

Glia. 2012 Feb;60(2):203-17. doi: 10.1002/glia.21255. Epub 2011 Nov 2.

50.

Treasures from the attic: transparencies digitally remastered and used for web-based pathology training and education.

Kalinski T, Zwönitzer R, Rossner M, Jonczyk-Weber T, Hofmann H, Roessner A, Guenther T.

Histopathology. 2011 Dec;59(6):1263-6. doi: 10.1111/j.1365-2559.2011.03972.x. Epub 2011 Oct 4. No abstract available.

PMID:
21973314

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